DK222186A - Fremgangsmaade til fremstilling af en fast form til oral anvendelsebaseret paa nifedipin med reguleret frigoerelse af aktivstoffet - Google Patents

Fremgangsmaade til fremstilling af en fast form til oral anvendelsebaseret paa nifedipin med reguleret frigoerelse af aktivstoffet Download PDF

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Publication number
DK222186A
DK222186A DK222186A DK222186A DK222186A DK 222186 A DK222186 A DK 222186A DK 222186 A DK222186 A DK 222186A DK 222186 A DK222186 A DK 222186A DK 222186 A DK222186 A DK 222186A
Authority
DK
Denmark
Prior art keywords
active substance
oral use
nifedipine
preparing
procedure
Prior art date
Application number
DK222186A
Other languages
English (en)
Other versions
DK222186D0 (da
DK172710B1 (da
Inventor
Vittorio Giudice
Vittorino Ravelli
Original Assignee
Pharmatec Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Pharmatec Spa filed Critical Pharmatec Spa
Publication of DK222186A publication Critical patent/DK222186A/da
Publication of DK222186D0 publication Critical patent/DK222186D0/da
Application granted granted Critical
Publication of DK172710B1 publication Critical patent/DK172710B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Cosmetics (AREA)
  • Electroplating And Plating Baths Therefor (AREA)
  • Surgical Instruments (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Steering Control In Accordance With Driving Conditions (AREA)
DK198602221A 1984-09-14 1986-05-13 Fremgangsmåde til fremstilling af en fast form til oral anvendelse baseret på nifedipin med reguleret frigørelse af aktivst DK172710B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT2267884 1984-09-14
IT22678/84A IT1178511B (it) 1984-09-14 1984-09-14 Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio
PCT/EP1985/000481 WO1986001717A1 (en) 1984-09-14 1985-09-04 Controlled release nifedipine preparation
EP8500481 1985-09-04

Publications (3)

Publication Number Publication Date
DK222186A true DK222186A (da) 1986-05-13
DK222186D0 DK222186D0 (da) 1986-05-13
DK172710B1 DK172710B1 (da) 1999-06-07

Family

ID=11199169

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198602221A DK172710B1 (da) 1984-09-14 1986-05-13 Fremgangsmåde til fremstilling af en fast form til oral anvendelse baseret på nifedipin med reguleret frigørelse af aktivst

Country Status (16)

Country Link
EP (1) EP0226588B1 (da)
JP (1) JPS62500660A (da)
AT (1) ATE61733T1 (da)
AU (1) AU588258B2 (da)
CA (1) CA1253079A (da)
DE (1) DE3582251D1 (da)
DK (1) DK172710B1 (da)
ES (1) ES8702137A1 (da)
FI (1) FI87991C (da)
IE (1) IE58490B1 (da)
IT (1) IT1178511B (da)
NO (1) NO171887C (da)
PT (1) PT81113B (da)
WO (1) WO1986001717A1 (da)
YU (1) YU45988B (da)
ZA (1) ZA856862B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1187751B (it) * 1985-10-15 1987-12-23 Eurand Spa Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute
SE8601624D0 (sv) * 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
DK173505B1 (da) * 1987-02-20 2001-01-15 Pharmatec Internat S R L Fremgangsmåde til fremstilling af en diltiazempellet med langsom afgivelse og anvendelse af således fremstillede pelleter t
GB8722306D0 (en) * 1987-09-22 1987-10-28 Aps Research Ltd Sustained-release formulation
GB8903328D0 (en) * 1989-02-14 1989-04-05 Ethical Pharma Ltd Nifedipine-containing pharmaceutical compositions and process for the preparation thereof
HU203041B (en) * 1989-03-14 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5122384A (en) * 1989-05-05 1992-06-16 Kv Pharmaceutical Company Oral once-per-day organic nitrate formulation which does not induce tolerance
GB9200607D0 (en) * 1992-01-13 1992-03-11 Ethical Pharma Ltd Pharmaceutical compositions containing nifedipine and process for the preparation thereof
WO1994005262A1 (en) * 1992-09-10 1994-03-17 F.H. Faulding & Co. Limited Sustained release matrix composition
US7060293B1 (en) 1994-05-25 2006-06-13 Purdue Pharma Powder-layered oral dosage forms
US6077533A (en) * 1994-05-25 2000-06-20 Purdue Pharma L.P. Powder-layered oral dosage forms
ES2168351T3 (es) * 1994-12-29 2002-06-16 Shire Deutschland Gmbh & Co Kg Preparaciones farmaceuticas que contienen nifedipina y procedimiento para su preparacion.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2453642A1 (fr) * 1979-04-12 1980-11-07 Sanofi Sa Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotoxine
DE3033919A1 (de) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
DE3433239A1 (de) * 1984-09-11 1986-03-20 Bayer Ag, 5090 Leverkusen Feste arzneizubereitung enthaltend nitrendipin und verfahren zu ihrer herstellung
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation

Also Published As

Publication number Publication date
DE3582251D1 (de) 1991-04-25
PT81113A (en) 1985-10-01
JPS62500660A (ja) 1987-03-19
NO171887C (no) 1993-05-19
PT81113B (pt) 1987-10-20
FI87991C (fi) 1993-03-25
NO861845L (no) 1986-05-07
AU4959485A (en) 1986-04-08
YU143985A (en) 1987-10-31
CA1253079A (en) 1989-04-25
IT1178511B (it) 1987-09-09
NO171887B (no) 1993-02-08
ES8702137A1 (es) 1987-01-16
YU45988B (sh) 1992-12-21
AU588258B2 (en) 1989-09-14
IE58490B1 (en) 1993-09-22
IT8422678A1 (it) 1986-03-14
IT8422678A0 (it) 1984-09-14
ES547707A0 (es) 1987-01-16
FI87991B (fi) 1992-12-15
ATE61733T1 (de) 1991-04-15
JPH0417932B2 (da) 1992-03-26
DK222186D0 (da) 1986-05-13
FI871116A7 (fi) 1987-03-13
DK172710B1 (da) 1999-06-07
ZA856862B (en) 1986-05-28
FI871116A0 (fi) 1987-03-13
EP0226588A1 (en) 1987-07-01
WO1986001717A1 (en) 1986-03-27
IE852262L (en) 1986-03-14
EP0226588B1 (en) 1991-03-20

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired