DK2231166T3 - Fedtsyrer med medium kædelængde, salte og triglycerider i kombination med gemcitabin til behandling af pankreascancer - Google Patents

Fedtsyrer med medium kædelængde, salte og triglycerider i kombination med gemcitabin til behandling af pankreascancer

Info

Publication number
DK2231166T3
DK2231166T3 DK08862479.6T DK08862479T DK2231166T3 DK 2231166 T3 DK2231166 T3 DK 2231166T3 DK 08862479 T DK08862479 T DK 08862479T DK 2231166 T3 DK2231166 T3 DK 2231166T3
Authority
DK
Denmark
Prior art keywords
gemcitabine
triglycerides
salts
treatment
medium
Prior art date
Application number
DK08862479.6T
Other languages
English (en)
Inventor
Lyne Gagnon
Lilianne Geerts
Christopher Penney
Original Assignee
Prometic Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prometic Biosciences Inc filed Critical Prometic Biosciences Inc
Application granted granted Critical
Publication of DK2231166T3 publication Critical patent/DK2231166T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK08862479.6T 2007-12-19 2008-12-18 Fedtsyrer med medium kædelængde, salte og triglycerider i kombination med gemcitabin til behandling af pankreascancer DK2231166T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US812907P 2007-12-19 2007-12-19
PCT/CA2008/002190 WO2009076761A1 (en) 2007-12-19 2008-12-18 Medium-chain length fatty acids, salts and triglycerides in combination with gemcitabine for treatment of pancreatic cancer

Publications (1)

Publication Number Publication Date
DK2231166T3 true DK2231166T3 (da) 2013-06-24

Family

ID=40795145

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08862479.6T DK2231166T3 (da) 2007-12-19 2008-12-18 Fedtsyrer med medium kædelængde, salte og triglycerider i kombination med gemcitabin til behandling af pankreascancer

Country Status (15)

Country Link
US (1) US8946190B2 (da)
EP (1) EP2231166B1 (da)
JP (1) JP5473937B2 (da)
KR (1) KR101603351B1 (da)
CN (1) CN101903028B (da)
AU (1) AU2008338204B2 (da)
BR (1) BRPI0821395A2 (da)
CA (1) CA2708679C (da)
DK (1) DK2231166T3 (da)
ES (1) ES2414617T3 (da)
MX (1) MX2010006867A (da)
NZ (1) NZ586249A (da)
PT (1) PT2231166E (da)
TW (1) TWI448290B (da)
WO (1) WO2009076761A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA022445B1 (ru) 2009-05-04 2016-01-29 Прометик Байосайенсиз Инк. Замещенные ароматические соединения, композиции на их основе и их фармацевтические применения
CN105997967B (zh) * 2010-10-27 2019-08-23 普罗米蒂克医药Smt有限公司 用于治疗癌症的化合物和组合物
CN102617679B (zh) * 2012-03-13 2014-11-26 北京大学 一种共轭亚油酸与吉西他滨连接的前体药物制备方法及其应用
WO2014126969A1 (en) 2013-02-12 2014-08-21 Bend Research, Inc. Solid dispersions of low-water solubility actives
US9737538B2 (en) 2013-02-12 2017-08-22 Bend Research, Inc. Solid dispersions of low-water solubility actives
MX377728B (es) 2013-02-28 2025-03-11 Pronova Biopharma Norge As Composición que comprende un compuesto lípido, un triglicerido y un tensioactivo, y métodos de uso de la misma.
WO2015116782A1 (en) 2014-01-29 2015-08-06 Board Of Regents, The University Of Texas System Nucleobase analogue derivatives and their applications
SG11202103011YA (en) 2018-10-11 2021-04-29 Basf As Aromatic compounds and pharmaceutical uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE168557T1 (de) * 1989-03-13 1998-08-15 Cellegy Pharma Inc Topische zubereitungen enthaltend aliphatische amine zur behandlung von hautkrankheiten
US6340705B1 (en) * 1999-09-10 2002-01-22 Monsanto Technology, Llc Use of α-linolenic acid metabolites for treatment or prevention of cancer
JP5026655B2 (ja) * 2001-04-18 2012-09-12 プロメティック、バイオサイエンシーズ、インコーポレーテッド 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体
EP1427366A2 (en) * 2001-08-29 2004-06-16 UMD, Inc. Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy
US20060012880A1 (en) * 2002-05-02 2006-01-19 Law Benjamin P Optical device with refractive and diffractive properties
ATE419846T1 (de) * 2003-02-07 2009-01-15 Prometic Biosciences Inc Fettsäuren mittlerer kettenlänge, glyceride und analoga als stimulatoren der erythropoiese
ES2264886B1 (es) * 2005-05-12 2008-02-01 Proyecto Empresarial Brudy, S.L. Utilizacion de acido docosahexaenoico para el tratamiento de enfermedades tumorales.

Also Published As

Publication number Publication date
TW200934494A (en) 2009-08-16
WO2009076761A1 (en) 2009-06-25
CN101903028A (zh) 2010-12-01
KR101603351B1 (ko) 2016-03-14
TWI448290B (zh) 2014-08-11
CA2708679A1 (en) 2009-06-25
US8946190B2 (en) 2015-02-03
EP2231166A4 (en) 2012-02-22
JP5473937B2 (ja) 2014-04-16
KR20100101134A (ko) 2010-09-16
HK1151244A1 (en) 2012-01-27
AU2008338204B2 (en) 2015-03-05
EP2231166A1 (en) 2010-09-29
US20100273731A1 (en) 2010-10-28
EP2231166B1 (en) 2013-03-20
ES2414617T3 (es) 2013-07-22
PT2231166E (pt) 2013-06-17
CN101903028B (zh) 2013-06-05
AU2008338204A1 (en) 2009-06-25
NZ586249A (en) 2012-05-25
BRPI0821395A2 (pt) 2015-06-16
CA2708679C (en) 2016-11-15
MX2010006867A (es) 2010-08-31
JP2011506492A (ja) 2011-03-03

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