DK2260873T3 - Pcylering af proteiner - Google Patents
Pcylering af proteinerInfo
- Publication number
- DK2260873T3 DK2260873T3 DK09162203.5T DK09162203T DK2260873T3 DK 2260873 T3 DK2260873 T3 DK 2260873T3 DK 09162203 T DK09162203 T DK 09162203T DK 2260873 T3 DK2260873 T3 DK 2260873T3
- Authority
- DK
- Denmark
- Prior art keywords
- pcyling
- proteins
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/548—Phosphates or phosphonates, e.g. bone-seeking
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09162203.5A EP2260873B1 (en) | 2009-06-08 | 2009-06-08 | Pcylation of proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2260873T3 true DK2260873T3 (da) | 2019-09-16 |
Family
ID=41011846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09162203.5T DK2260873T3 (da) | 2009-06-08 | 2009-06-08 | Pcylering af proteiner |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP2260873B1 (da) |
| DK (1) | DK2260873T3 (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1988910B1 (en) * | 2006-02-28 | 2017-12-06 | Kodiak Sciences Inc. | Acryloyloxyethylphosphorylcholine containing polymer conjugates and their preparation |
| WO2011075185A1 (en) | 2009-12-18 | 2011-06-23 | Oligasis | Targeted drug phosphorylcholine polymer conjugates |
| ES2742216T3 (es) * | 2010-04-15 | 2020-02-13 | Kodiak Sciences Inc | Polímeros que contienen zwitteriones de alto peso molecular |
| CN105102485B (zh) * | 2013-02-05 | 2019-04-19 | 特普塞拉公司 | 磷酸胆碱缀合物及其用途 |
| US10046021B2 (en) | 2013-02-05 | 2018-08-14 | Tpcera Ltd. | Phosphorylcholine conjugates and uses thereof |
| WO2015035342A2 (en) | 2013-09-08 | 2015-03-12 | Oligasis Llc | Factor viii zwitterionic polymer conjugates |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| WO2016059377A1 (en) | 2014-10-14 | 2016-04-21 | Polytherics Limited | Process for the conjugation of a peptide or protein with a reagent comprising a leaving group including a portion of peg |
| KR20210013299A (ko) | 2014-10-17 | 2021-02-03 | 코디악 사이언시스 인코포레이티드 | 부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트 |
| CN107530445B (zh) | 2014-11-26 | 2021-01-05 | 加利福尼亚大学董事会 | 用于蛋白质递送的隐形纳米胶囊 |
| KR20250057128A (ko) | 2015-12-30 | 2025-04-28 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| WO2017178828A1 (en) | 2016-04-14 | 2017-10-19 | Polytherics Limited | Conjugates and conjugating reagents comprising a linker that includes at least two (-ch2-ch2-0-) units in a ring |
| GB201608936D0 (en) | 2016-05-20 | 2016-07-06 | Polytherics Ltd | Novel conjugates and novel conjugating reagents |
| US12071476B2 (en) | 2018-03-02 | 2024-08-27 | Kodiak Sciences Inc. | IL-6 antibodies and fusion constructs and conjugates thereof |
| AU2020364071A1 (en) | 2019-10-10 | 2022-05-26 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| WO2022255479A1 (ja) * | 2021-06-04 | 2022-12-08 | タグシクス・バイオ株式会社 | 中分子化合物の血中動態改善のための中分子化合物コンジュゲート体およびその製造方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US6071980A (en) | 1997-08-27 | 2000-06-06 | E. I. Du Pont De Nemours And Company | Atom transfer radical polymerization |
| AUPP337298A0 (en) | 1998-05-07 | 1998-05-28 | University Of Melbourne, The | Process for microgel preparation |
| JP4593786B2 (ja) | 1998-09-29 | 2010-12-08 | チバ ホールディング インコーポレーテッド | Ｎ→ｏ末端基を含むポリマーの製造方法 |
| JP5049452B2 (ja) | 2000-10-06 | 2012-10-17 | バイオコンパティブルズ ユーケー リミテッド | 両性イオン重合体 |
| US8048408B2 (en) | 2002-01-16 | 2011-11-01 | Biocompatibles Uk Limited | Polymer conjugates |
| AU2003217009A1 (en) | 2002-03-07 | 2003-09-16 | Biocompatibles Uk Limited | Compositions of polymers |
| GB0301014D0 (en) | 2003-01-16 | 2003-02-19 | Biocompatibles Ltd | Conjugation reactions |
| EP1988910B1 (en) * | 2006-02-28 | 2017-12-06 | Kodiak Sciences Inc. | Acryloyloxyethylphosphorylcholine containing polymer conjugates and their preparation |
| WO2008098930A1 (en) | 2007-02-14 | 2008-08-21 | Biocompatibes Uk Limited | Derivatisation of biological molecules |
-
2009
- 2009-06-08 DK DK09162203.5T patent/DK2260873T3/da active
- 2009-06-08 EP EP09162203.5A patent/EP2260873B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2260873A1 (en) | 2010-12-15 |
| EP2260873B1 (en) | 2019-07-24 |
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