DK2598514T3 - Proteinoprensning - Google Patents

Proteinoprensning Download PDF

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Publication number
DK2598514T3
DK2598514T3 DK11736364.8T DK11736364T DK2598514T3 DK 2598514 T3 DK2598514 T3 DK 2598514T3 DK 11736364 T DK11736364 T DK 11736364T DK 2598514 T3 DK2598514 T3 DK 2598514T3
Authority
DK
Denmark
Prior art keywords
protein purification
purification
protein
Prior art date
Application number
DK11736364.8T
Other languages
English (en)
Inventor
Mariangela Spitali
Jonathan Symmons
Richard Whitcombe
Mark Robert Pearce-Higgins
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Application granted granted Critical
Publication of DK2598514T3 publication Critical patent/DK2598514T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/306—Extraction; Separation; Purification by precipitation by crystallization
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
DK11736364.8T 2010-07-27 2011-07-26 Proteinoprensning DK2598514T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1012603.5A GB201012603D0 (en) 2010-07-27 2010-07-27 Protein purification
PCT/EP2011/062837 WO2012013682A2 (en) 2010-07-27 2011-07-26 Protein purification

Publications (1)

Publication Number Publication Date
DK2598514T3 true DK2598514T3 (da) 2020-11-16

Family

ID=42752872

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11736364.8T DK2598514T3 (da) 2010-07-27 2011-07-26 Proteinoprensning

Country Status (23)

Country Link
US (4) US9309280B2 (da)
EP (2) EP3747893A1 (da)
JP (1) JP5893622B2 (da)
KR (1) KR101921767B1 (da)
CN (2) CN107793477A (da)
AU (1) AU2011284896B2 (da)
BR (1) BR112013000623B1 (da)
CA (1) CA2805132C (da)
CY (1) CY1123619T1 (da)
DK (1) DK2598514T3 (da)
ES (1) ES2834967T3 (da)
GB (1) GB201012603D0 (da)
HK (1) HK1246330A1 (da)
HU (1) HUE052159T2 (da)
IL (1) IL223931A (da)
LT (1) LT2598514T (da)
PL (1) PL2598514T3 (da)
PT (1) PT2598514T (da)
RS (1) RS61095B1 (da)
SG (2) SG186957A1 (da)
SI (1) SI2598514T1 (da)
SM (1) SMT202000644T1 (da)
WO (1) WO2012013682A2 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201012603D0 (en) * 2010-07-27 2010-09-08 Ucb Pharma Sa Protein purification
SG11201404991YA (en) 2012-02-23 2014-09-26 Stage Cell Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
DK2864346T3 (da) * 2012-06-21 2019-02-04 Synthon Biopharmaceuticals Bv Fremgangsmåde til oprensning af et antistof.
WO2014110246A1 (en) * 2013-01-09 2014-07-17 Shire Human Genetic Therapies, Inc. Methods for purification of arylsulfatase a
US9914770B2 (en) 2013-04-30 2018-03-13 Intas Pharmaceuticals Ltd Cloning, expression and purification method for the preparation of ranibizumab
US9951101B2 (en) 2013-12-12 2018-04-24 Emd Millipore Corporation Protein separations using an acrylamide containing filter
ES3046837T3 (en) 2014-12-22 2025-12-02 UCB Biopharma SRL Method of protein manufacture
IL282614B2 (en) 2015-02-06 2024-02-01 Cell Idx Inc Antigen-conjugated immune reagents
RU2761555C2 (ru) 2015-10-22 2021-12-09 Джуно Терапьютикс Гмбх Способы, наборы, средства и устройства для трансдукции
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
GB201602938D0 (en) 2016-02-19 2016-04-06 Ucb Biopharma Sprl Protein purification
WO2018017606A1 (en) * 2016-07-18 2018-01-25 Cell Idx, Inc. Antigen-coupled hybridization reagents
EP3824906A1 (en) 2016-12-21 2021-05-26 Amgen Inc. Anti-tnf alpha antibody formulations
AU2018260380B2 (en) 2017-04-27 2025-02-13 Juno Therapeutics Gmbh Oligomeric particle reagents and methods of use thereof
US10717023B1 (en) * 2017-10-11 2020-07-21 Roddy Kevin Stafford Method for continuous purification
CN110241012B (zh) * 2018-03-09 2022-11-01 嘉和生物药业有限公司 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用
WO2020089343A1 (en) 2018-10-31 2020-05-07 Juno Therapeutics Gmbh Methods for selection and stimulation of cells and apparatus for same
WO2021176311A1 (en) * 2020-03-05 2021-09-10 Lupin Limited An improved purification process for ranibizumab
CA3236213A1 (en) 2021-10-27 2023-05-04 Eugene ZURLO Compositions and methods for isolating proteins
AU2023281650A1 (en) 2022-05-30 2024-10-17 Hanall Biopharma Co., Ltd. Anti-fcrn antibody or antigen binding fragment thereof with improved stability

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
US5655866A (en) 1995-03-20 1997-08-12 Bellanca; Joseph V. Method of folding a signature for use in bookbinding
ES2293661T3 (es) 1996-11-27 2008-03-16 Genentech, Inc. Purificacion por afinidad de polipeptido en una matriz de proteinas a.
CN1283228A (zh) * 1997-12-24 2001-02-07 武田药品工业株式会社 多肽、其生产方法及应用
ATE370961T1 (de) * 1998-05-06 2007-09-15 Genentech Inc Reinigung von antikörpern durch ionenaustauschchromatographie
GB0013810D0 (en) 2000-06-06 2000-07-26 Celltech Chiroscience Ltd Biological products
SI1501369T1 (sl) * 2002-04-26 2015-10-30 Genentech, Inc. Neafinitetno čiščenje proteinov
PT1543038T (pt) 2002-09-11 2017-07-07 Genentech Inc Purificação de proteína
GB0224082D0 (en) * 2002-10-16 2002-11-27 Celltech R&D Ltd Biological products
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
BRPI0608584B8 (pt) * 2005-03-11 2021-05-25 Wyeth Corp métodos de recuperar um produto purificado
US20100190210A1 (en) * 2006-03-20 2010-07-29 Medarex, Inc. Protein Purification
CN102391358B (zh) * 2006-04-05 2016-08-10 艾伯维生物技术有限公司 抗体纯化
US20080000431A1 (en) 2006-06-29 2008-01-03 Stephen Longo Dog leash assembly
HUE024877T2 (en) 2007-10-30 2016-02-29 Genentech Inc Antibody purification by cation exchange chromatography
WO2009135656A1 (en) * 2008-05-06 2009-11-12 Lonza Biologics Plc. A method for the purification of antibodies using displacement chromatography
CN102257004A (zh) * 2008-10-20 2011-11-23 雅培制药有限公司 与il-12结合的抗体及其纯化方法
CN104974251A (zh) * 2008-10-20 2015-10-14 Abbvie公司 在抗体纯化过程中的病毒灭活
GB201012603D0 (en) * 2010-07-27 2010-09-08 Ucb Pharma Sa Protein purification

Also Published As

Publication number Publication date
ES2834967T3 (es) 2021-06-21
IL223931A (en) 2017-10-31
SMT202000644T1 (it) 2021-01-05
LT2598514T (lt) 2020-12-28
CA2805132C (en) 2020-01-14
CY1123619T1 (el) 2022-03-24
EP2598514A2 (en) 2013-06-05
US9309280B2 (en) 2016-04-12
BR112013000623A2 (pt) 2016-05-24
CA2805132A1 (en) 2012-02-02
SG10201802316VA (en) 2018-04-27
RS61095B1 (sr) 2020-12-31
GB201012603D0 (en) 2010-09-08
WO2012013682A2 (en) 2012-02-02
US20190135909A1 (en) 2019-05-09
KR20130131307A (ko) 2013-12-03
AU2011284896A1 (en) 2013-01-24
US10189897B2 (en) 2019-01-29
JP5893622B2 (ja) 2016-03-23
US11339214B2 (en) 2022-05-24
WO2012013682A3 (en) 2012-05-18
PL2598514T3 (pl) 2021-03-08
CN107793477A (zh) 2018-03-13
SG186957A1 (en) 2013-02-28
HK1246330A1 (zh) 2018-09-07
AU2011284896B2 (en) 2016-06-16
US20160108119A1 (en) 2016-04-21
EP2598514B1 (en) 2020-09-09
BR112013000623B1 (pt) 2022-10-11
US20220289832A1 (en) 2022-09-15
US20130184439A1 (en) 2013-07-18
CN103025752A (zh) 2013-04-03
KR101921767B1 (ko) 2018-11-23
SI2598514T1 (sl) 2021-01-29
PT2598514T (pt) 2020-12-15
HUE052159T2 (hu) 2021-04-28
JP2013532673A (ja) 2013-08-19
EP3747893A1 (en) 2020-12-09

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