DK227985A - Kloning og karakterisering af det humane interleukin 1 gen - Google Patents

Kloning og karakterisering af det humane interleukin 1 gen Download PDF

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Publication number
DK227985A
DK227985A DK227985A DK227985A DK227985A DK 227985 A DK227985 A DK 227985A DK 227985 A DK227985 A DK 227985A DK 227985 A DK227985 A DK 227985A DK 227985 A DK227985 A DK 227985A
Authority
DK
Denmark
Prior art keywords
gen
cloning
characterization
human interleukin
interleukin
Prior art date
Application number
DK227985A
Other languages
English (en)
Other versions
DK227985D0 (da
Inventor
D P Cerretti
Iii P J Conlon
D J Crosman
K H Grabstein
T P Hopp
S R Kronheim
A D Larsen
C J March
B A Mosley
V L Price
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of DK227985D0 publication Critical patent/DK227985D0/da
Publication of DK227985A publication Critical patent/DK227985A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK227985A 1985-01-17 1985-05-22 Kloning og karakterisering af det humane interleukin 1 gen DK227985A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69241685A 1985-01-17 1985-01-17
US72176585A 1985-04-10 1985-04-10

Publications (2)

Publication Number Publication Date
DK227985D0 DK227985D0 (da) 1985-05-22
DK227985A true DK227985A (da) 1986-07-18

Family

ID=27104963

Family Applications (1)

Application Number Title Priority Date Filing Date
DK227985A DK227985A (da) 1985-01-17 1985-05-22 Kloning og karakterisering af det humane interleukin 1 gen

Country Status (6)

Country Link
EP (1) EP0188864B1 (da)
JP (1) JPH064674B2 (da)
AU (1) AU577856B2 (da)
DE (1) DE3584883D1 (da)
DK (1) DK227985A (da)
NZ (1) NZ212173A (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3588241T2 (de) * 1984-05-18 2002-12-05 Massachusetts Institute Of Technology, Cambridge Menschliche IL-1 cDNS-Sequenzen die für biologisch aktive menschliche IL-1-Proteine kodieren
EP0569687B1 (en) * 1984-05-18 2002-08-21 New England Medical Center Hospitals, Inc. Human IL-1 cDNA sequences encoding biologically-active human IL-1 proteins
US5998578A (en) * 1984-05-18 1999-12-07 New England Medical Center Hospitals, Inc. Biologically active fragments of IL-1β
CA1341433C (en) * 1984-06-19 2003-06-24 Douglas P. Cerretti Purification of interleukin 1
DK172052B1 (da) * 1984-12-21 1997-09-29 Otsuka Pharma Co Ltd Antitumor-aktivt stof, fremgangsmåde til dets fremstilling, lægemiddel indeholdende stoffet, gen kodende for stoffet, vektor indeholdende genet samt rekombinant mikroorganisme transformet med en sådan vektor
US6107465A (en) * 1984-12-21 2000-08-22 Otsuka Pharmaceutical Co., Ltd. IL-1β and derivatives thereof and drugs
US5342614A (en) * 1984-12-21 1994-08-30 Otsuka Pharmaceutical Co., Ltd. Method of treating arthritus or inflammation with IL-1β or derivatives thereof
DE3587605T2 (de) * 1984-12-25 1994-03-17 Dainippon Pharmaceutical Co Interleukin-1 und dessen Derivat.
DE3683186D1 (de) 1985-04-25 1992-02-13 Hoffmann La Roche Rekombinantes humaninterleukin-1.
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
US5120534A (en) * 1988-07-29 1992-06-09 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and medicament for treating thrombocytopenia
US5811523A (en) 1988-11-10 1998-09-22 Trinchieri; Giorgio Antibodies to natural killer stimulatory factor
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
EP0611302B1 (en) * 1991-10-15 2000-03-29 MULLARKEY, Michael F. Receptors for treating late phase inflammatory responses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU579089B2 (en) * 1983-02-08 1988-11-17 Biogen, Inc. Human interleukin-2-like polypeptides
ES8708014A1 (es) * 1984-06-07 1987-09-01 Murphy John R Un procedimiento para preparar un gen fusionado que codifica una proteina hibrida susceptible de marcado y empleo en diagnosis.
CA1341433C (en) * 1984-06-19 2003-06-24 Douglas P. Cerretti Purification of interleukin 1
JP2579747B2 (ja) * 1984-12-25 1997-02-12 大日本製薬株式会社 ヒトインタ−ロイキン１をコ−ドする新規ｄｎａ
DE3587605T2 (de) * 1984-12-25 1994-03-17 Dainippon Pharmaceutical Co Interleukin-1 und dessen Derivat.

Also Published As

Publication number Publication date
EP0188864B1 (en) 1991-12-11
JPS61170395A (ja) 1986-08-01
EP0188864A1 (en) 1986-07-30
AU577856B2 (en) 1988-10-06
NZ212173A (en) 1988-02-29
AU4265985A (en) 1986-07-24
JPH064674B2 (ja) 1994-01-19
DK227985D0 (da) 1985-05-22
DE3584883D1 (de) 1992-01-23

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