DK228687A - 2-pyridyl-penem-forbindelser og salte deraf samt deres fremstilling og anvendelse - Google Patents

2-pyridyl-penem-forbindelser og salte deraf samt deres fremstilling og anvendelse

Info

Publication number: DK228687A
Authority: DK; Denmark
Prior art keywords: pyridyl; compounds; salts; preparation; penem compounds
Prior art date: 1986-05-06

Application number

DK228687A

Other languages

English (en)

Other versions

DK169623B1 (da

DK228687D0 (da

Inventor

Marc Lang

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-05-06

Filing date

1987-05-05

Publication date

1987-11-07

1987-05-05 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1987-05-05 Publication of DK228687D0 publication Critical patent/DK228687D0/da

1987-11-07 Publication of DK228687A publication Critical patent/DK228687A/da

1994-12-27 Application granted granted Critical

1994-12-27 Publication of DK169623B1 publication Critical patent/DK169623B1/da

Links

CWFAMVUHPHYDIO-SNVBAGLBSA-N (5r)-3-pyridin-2-yl-4-thia-1-azabicyclo[3.2.0]hept-2-en-7-one Chemical class S([C@@H]1CC(N1C=1)=O)C=1C1=CC=CC=N1 CWFAMVUHPHYDIO-SNVBAGLBSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Cephalosporin Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Inks, Pencil-Leads, Or Crayons (AREA)

DK228687A 1986-05-06 1987-05-05 2-Pyridyl-penem-forbindelser og salte deraf, fremgangsmåde til deres fremstilling samt farmaceutiske præparater indeholdende disse forbindelser DK169623B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH184686		1986-05-06
CH184686		1986-05-06

Publications (3)

Publication Number	Publication Date
DK228687D0 DK228687D0 (da)	1987-05-05
DK228687A true DK228687A (da)	1987-11-07
DK169623B1 DK169623B1 (da)	1994-12-27

Family

ID=4219979

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK228687A DK169623B1 (da)	1986-05-06	1987-05-05	2-Pyridyl-penem-forbindelser og salte deraf, fremgangsmåde til deres fremstilling samt farmaceutiske præparater indeholdende disse forbindelser

Country Status (14)

Country	Link
US (1)	US4826832A (da)
EP (1)	EP0246187B1 (da)
JP (1)	JPS62263183A (da)
AT (1)	ATE72438T1 (da)
AU (1)	AU603795B2 (da)
CA (1)	CA1293502C (da)
DE (1)	DE3776590D1 (da)
DK (1)	DK169623B1 (da)
ES (1)	ES2038207T3 (da)
GR (1)	GR3003735T3 (da)
IE (1)	IE59714B1 (da)
NZ (1)	NZ220195A (da)
PT (1)	PT84819B (da)
ZA (1)	ZA873198B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0003960B1 (de) *	1978-02-02	1983-06-29	Ciba-Geigy Ag	6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
EP0215739B1 (de) *	1985-09-11	1993-09-01	Ciba-Geigy Ag	Synthese von Beta-Lactamverbindungen
GB8716679D0 (en) *	1987-07-15	1987-08-19	Erba Farmitalia	Penem derivatives
EP0462521A1 (en) *	1990-06-19	1991-12-27	Takeda Chemical Industries, Ltd.	Crystalline penem, its production and use
US5492903A (en) *	1990-06-19	1996-02-20	Takeda Chemical Industries Ltd.	Crystalline esters of (+)-(5R, 6S)-6-[(R)-1-hydroxyethyl]-3-(3-pyridyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]he
EP0499274A1 (en) *	1991-02-15	1992-08-19	Takeda Chemical Industries, Ltd.	Crystalline penem, its production and use
CA2110184C (en) *	1991-06-06	2003-04-15	J. Stuart Cumming	Intraocular lens with haptic anchor plate
EP0597401A3 (en) *	1992-11-11	1995-07-26	Takeda Chemical Industries Ltd	Preparation of penemes.
US20040202714A1 (en) *	1999-10-12	2004-10-14	Daiichi Suntory Pharma Co., Ltd.	Oral pharmaceutical composition
DE60008497T2 (de) *	1999-10-12	2004-12-02	Daiichi Suntory Pharma Co., Ltd.	Arzneimittel zur oralen verabreichung

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4168314A (en) *	1977-11-17	1979-09-18	Merck & Co., Inc.	6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0003960B1 (de) *	1978-02-02	1983-06-29	Ciba-Geigy Ag	6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
US4272437A (en) *	1978-12-18	1981-06-09	Bristol-Myers Company	Antibacterial agents, and 4-thio azetidinone intermediates
IL58576A (en) *	1978-12-18	1985-12-31	Bristol Myers Co	2-substituted and 2,6-disubstituted penem compounds,their preparation and pharmaceutical compositions containing them
JPS5625110A (en) *	1978-12-18	1981-03-10	Bristol Myers Co	Antibacterial
US4386030A (en) *	1979-12-31	1983-05-31	Merck & Co., Inc.	Process for preparing 6-(1'-hydroxyethyl)-2-substituted-pen-2-em-3-carboxylic acid
DE3277696D1 (en) *	1981-07-15	1987-12-23	Sumitomo Pharma	Carboxylic beta-lactam compounds and the preparation thereof
NZ201471A (en) *	1981-08-10	1985-09-13	Merck & Co Inc	Antibacterial compositions containing penems and dipeptidase inhibitors
EP0109362A1 (de) *	1982-11-16	1984-05-23	Ciba-Geigy Ag	Heterocyclylverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren
US4540580A (en) *	1982-11-16	1985-09-10	Schering Corporation	2-[(1'R)-1'-Aminoalkyl]penems
DE3366926D1 (en) *	1982-11-16	1986-11-20	Schering Corp	Penems, pharmaceutical compositions containing them, process for preparing them
EP0148128A3 (de) *	1983-12-30	1985-08-07	Ciba-Geigy Ag	Neue optisch aktive Penem-Verbindungen
GB8416652D0 (en) *	1984-06-29	1984-08-01	Erba Farmitalia	Penem derivatives
US4617300A (en) *	1984-09-21	1986-10-14	Schering Corporation	2(N-heterocyclyl) penems
EP0199675A1 (de) *	1985-04-17	1986-10-29	Ciba-Geigy Ag	Heterocyclyl-penem-Verbindungen

1987
- 1987-04-27 US US07/042,768 patent/US4826832A/en not_active Expired - Lifetime
- 1987-04-30 ES ES198787810278T patent/ES2038207T3/es not_active Expired - Lifetime
- 1987-04-30 AT AT87810278T patent/ATE72438T1/de not_active IP Right Cessation
- 1987-04-30 EP EP87810278A patent/EP0246187B1/de not_active Expired - Lifetime
- 1987-04-30 DE DE8787810278T patent/DE3776590D1/de not_active Expired - Lifetime
- 1987-05-01 JP JP62106454A patent/JPS62263183A/ja active Granted
- 1987-05-04 CA CA000536310A patent/CA1293502C/en not_active Expired - Lifetime
- 1987-05-04 PT PT84819A patent/PT84819B/pt unknown
- 1987-05-05 AU AU72512/87A patent/AU603795B2/en not_active Expired
- 1987-05-05 DK DK228687A patent/DK169623B1/da not_active IP Right Cessation
- 1987-05-05 NZ NZ220195A patent/NZ220195A/xx unknown
- 1987-05-05 ZA ZA873198A patent/ZA873198B/xx unknown
- 1987-05-11 IE IE118287A patent/IE59714B1/en not_active IP Right Cessation
1992
- 1992-02-06 GR GR910402104T patent/GR3003735T3/el unknown

Also Published As

Publication number	Publication date
JPH0339514B2 (da)	1991-06-14
IE871182L (en)	1987-11-06
IE59714B1 (en)	1994-03-23
PT84819A (en)	1987-06-01
AU603795B2 (en)	1990-11-29
GR3003735T3 (da)	1993-03-16
DE3776590D1 (de)	1992-03-19
NZ220195A (en)	1989-01-06
DK169623B1 (da)	1994-12-27
ATE72438T1 (de)	1992-02-15
EP0246187B1 (de)	1992-02-05
US4826832A (en)	1989-05-02
AU7251287A (en)	1987-11-12
ES2038207T3 (es)	1993-07-16
CA1293502C (en)	1991-12-24
ZA873198B (en)	1987-12-30
EP0246187A3 (en)	1988-03-16
PT84819B (pt)	1989-12-29
DK228687D0 (da)	1987-05-05
JPS62263183A (ja)	1987-11-16
EP0246187A2 (de)	1987-11-19

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Legal Events

Date	Code	Title
1990-06-11	ATS	Application withdrawn
1994-12-27	B1	Patent granted (law 1993)
2007-05-21	PUP	Patent expired