DK2338052T3 - Fremgangsmåde og anordning til bestemmelse af mængden af magnetisk-mærkede målkomponenter - Google Patents

Fremgangsmåde og anordning til bestemmelse af mængden af magnetisk-mærkede målkomponenter Download PDF

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Publication number
DK2338052T3
DK2338052T3 DK09808959.2T DK09808959T DK2338052T3 DK 2338052 T3 DK2338052 T3 DK 2338052T3 DK 09808959 T DK09808959 T DK 09808959T DK 2338052 T3 DK2338052 T3 DK 2338052T3
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DK
Denmark
Prior art keywords
determining
labeled target
target components
magnetically labeled
magnetically
Prior art date
Application number
DK09808959.2T
Other languages
English (en)
Inventor
Toon H Evers
Wendy U Dittmer
Original Assignee
Koninklijke Philips Nv
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Publication date
Application filed by Koninklijke Philips Nv filed Critical Koninklijke Philips Nv
Application granted granted Critical
Publication of DK2338052T3 publication Critical patent/DK2338052T3/da

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/02Measuring direction or magnitude of magnetic fields or magnetic flux
    • G01R33/06Measuring direction or magnitude of magnetic fields or magnetic flux using galvano-magnetic devices
    • G01R33/09Magnetoresistive devices
    • G01R33/093Magnetoresistive devices using multilayer structures, e.g. giant magnetoresistance sensors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/12Measuring magnetic properties of articles or specimens of solids or fluids
    • G01R33/1269Measuring magnetic properties of articles or specimens of solids or fluids of molecules labeled with magnetic beads
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electrochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK09808959.2T 2008-10-16 2009-10-06 Fremgangsmåde og anordning til bestemmelse af mængden af magnetisk-mærkede målkomponenter DK2338052T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08166810 2008-10-16
PCT/IB2009/054372 WO2010044005A2 (en) 2008-10-16 2009-10-06 Method and device for determining the amount of magnetically labeled target components

Publications (1)

Publication Number Publication Date
DK2338052T3 true DK2338052T3 (da) 2020-02-17

Family

ID=42028175

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09808959.2T DK2338052T3 (da) 2008-10-16 2009-10-06 Fremgangsmåde og anordning til bestemmelse af mængden af magnetisk-mærkede målkomponenter

Country Status (9)

Country Link
US (1) US9023651B2 (da)
EP (1) EP2338052B1 (da)
JP (1) JP5567577B2 (da)
CN (1) CN102187222B (da)
BR (1) BRPI0914018A2 (da)
DK (1) DK2338052T3 (da)
ES (1) ES2773075T3 (da)
RU (1) RU2530715C2 (da)
WO (1) WO2010044005A2 (da)

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JP5937019B2 (ja) * 2010-03-12 2016-06-22 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 磁気センサに基づく結合反応速度の定量的な分析
US20140099663A1 (en) * 2010-11-15 2014-04-10 Regents Of The University Of Minnesota Gmr sensor
US9841421B2 (en) 2010-11-30 2017-12-12 Koninklijke Philips N.V. Sensor device for magnetically actuated particles
CN103917638A (zh) * 2011-09-08 2014-07-09 Nexusdx股份有限公司 多级分析物检定
WO2013102850A1 (en) 2012-01-04 2013-07-11 Insituto De Engenharia De Sistemas E Computadores Para Os Microsistemas E As Nanotecnologias Monolithic device combining cmos with magnetoresistive sensors
CA2804843C (en) * 2012-02-06 2021-02-02 Ortho-Clinical Diagnostics, Inc. Multiple time windows for extending the range of an assay
EP2685273A1 (en) * 2012-07-13 2014-01-15 Université Montpellier 2, Sciences et Techniques Micromagnetometry detection system and method for detecting magnetic signatures of magnetic materials
RU2653145C2 (ru) 2012-09-04 2018-05-07 Конинклейке Филипс Н.В. Измерительное устройство и способ отбора образцов
US11078298B2 (en) 2016-10-28 2021-08-03 Banyan Biomarkers, Inc. Antibodies to ubiquitin C-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) and related methods
JP7455529B2 (ja) 2019-08-01 2024-03-26 キヤノンメディカルシステムズ株式会社 検体測定装置及び検体測定装置の制御方法
WO2022139819A1 (en) * 2020-12-22 2022-06-30 Hp Health Solutions Inc. Washing magnetizing microparticles in a fluid density column

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US5846708A (en) 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
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GB9609653D0 (en) 1996-05-09 1996-07-10 Applied Research Ars Holding N Method of assay
US5885839A (en) * 1997-04-15 1999-03-23 Lxn Corporation Methods of determining initiation and variable end points for measuring a chemical reaction
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JP4585170B2 (ja) * 2000-10-03 2010-11-24 ミナーヴァ・バイオテクノロジーズ・コーポレーション 流動の中断に基づく相互作用の電子検出および相互作用の検出
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WO2003102546A2 (en) * 2002-05-31 2003-12-11 The Regents Of The University Of California Method and apparatus for detecting substances of interest
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US20060194327A1 (en) 2003-07-30 2006-08-31 Koninklijke Philips Electronics N.V. On-chip magnetic particle sensor with improved snr
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Also Published As

Publication number Publication date
CN102187222A (zh) 2011-09-14
CN102187222B (zh) 2014-05-07
WO2010044005A3 (en) 2010-07-08
WO2010044005A2 (en) 2010-04-22
JP2012506043A (ja) 2012-03-08
EP2338052A2 (en) 2011-06-29
RU2011119508A (ru) 2012-11-27
US9023651B2 (en) 2015-05-05
BRPI0914018A2 (pt) 2015-10-27
ES2773075T3 (es) 2020-07-09
EP2338052B1 (en) 2019-11-20
US20110207229A1 (en) 2011-08-25
JP5567577B2 (ja) 2014-08-06
RU2530715C2 (ru) 2014-10-10

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