DK2360475T3 - Fremgangsmåde og kit til detektion af tidlig indtræden af renal tubulær celleskade - Google Patents

Fremgangsmåde og kit til detektion af tidlig indtræden af renal tubulær celleskade Download PDF

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Publication number
DK2360475T3
DK2360475T3 DK10183320.0T DK10183320T DK2360475T3 DK 2360475 T3 DK2360475 T3 DK 2360475T3 DK 10183320 T DK10183320 T DK 10183320T DK 2360475 T3 DK2360475 T3 DK 2360475T3
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Denmark
Prior art keywords
ngal
renal
kit
cell injury
early onset
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DK10183320.0T
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English (en)
Inventor
Prased Devarajan
Jonathan M Barasch
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Childrens Hospital Med Ct
Univ Columbia
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Application filed by Childrens Hospital Med Ct, Univ Columbia filed Critical Childrens Hospital Med Ct
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Publication of DK2360475T3 publication Critical patent/DK2360475T3/da

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK10183320.0T 2003-03-27 2004-03-26 Fremgangsmåde og kit til detektion af tidlig indtræden af renal tubulær celleskade DK2360475T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45814303P 2003-03-27 2003-03-27
US48159603P 2003-11-04 2003-11-04
EP08169401.0A EP2083270B1 (en) 2003-03-27 2004-03-26 A method and kit for detecting the early onset of renal tubular cell injury

Publications (1)

Publication Number Publication Date
DK2360475T3 true DK2360475T3 (da) 2020-01-06

Family

ID=33135089

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04758356.2T DK1616184T4 (da) 2003-03-27 2004-03-26 Fremgangsmåde og kit til at påvise tidlig begyndelse af renal tubulær cellebeskadigelse
DK10183320.0T DK2360475T3 (da) 2003-03-27 2004-03-26 Fremgangsmåde og kit til detektion af tidlig indtræden af renal tubulær celleskade

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK04758356.2T DK1616184T4 (da) 2003-03-27 2004-03-26 Fremgangsmåde og kit til at påvise tidlig begyndelse af renal tubulær cellebeskadigelse

Country Status (14)

Country Link
US (11) US20040219603A1 (da)
EP (3) EP2360475B1 (da)
JP (2) JP5392980B2 (da)
CN (1) CN102183656B (da)
AT (1) ATE437371T1 (da)
AU (1) AU2004225472B2 (da)
BR (1) BRPI0408802B8 (da)
CA (1) CA2520658A1 (da)
DE (1) DE602004022150D1 (da)
DK (2) DK1616184T4 (da)
ES (3) ES2754753T3 (da)
MX (1) MXPA05010385A (da)
NZ (1) NZ543028A (da)
WO (1) WO2004088276A2 (da)

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US20150185231A1 (en) 2015-07-02
ES2330005T5 (es) 2018-06-20
DK1616184T4 (da) 2018-08-13
DK1616184T3 (da) 2009-10-19
CA2520658A1 (en) 2004-10-14
EP2083270B1 (en) 2019-06-12
WO2004088276A3 (en) 2004-11-25
AU2004225472B2 (en) 2011-02-10
CN102183656B (zh) 2014-04-16
US20040219603A1 (en) 2004-11-04
US20100227418A1 (en) 2010-09-09
EP1616184A2 (en) 2006-01-18
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AU2004225472A1 (en) 2004-10-14
US20130137116A1 (en) 2013-05-30
BRPI0408802B1 (pt) 2019-08-20
WO2004088276A2 (en) 2004-10-14
ATE437371T1 (de) 2009-08-15
JP2006521565A (ja) 2006-09-21
JP5392980B2 (ja) 2014-01-22
MXPA05010385A (es) 2006-03-08
EP2360475B1 (en) 2019-10-02
BRPI0408802B8 (pt) 2021-07-27
DE602004022150D1 (de) 2009-09-03
ES2754753T3 (es) 2020-04-20
US20090181407A1 (en) 2009-07-16
US20090123941A1 (en) 2009-05-14
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US20070254370A1 (en) 2007-11-01
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