DK2361380T3 - Planar sensor - Google Patents
Planar sensor Download PDFInfo
- Publication number
- DK2361380T3 DK2361380T3 DK09804119T DK09804119T DK2361380T3 DK 2361380 T3 DK2361380 T3 DK 2361380T3 DK 09804119 T DK09804119 T DK 09804119T DK 09804119 T DK09804119 T DK 09804119T DK 2361380 T3 DK2361380 T3 DK 2361380T3
- Authority
- DK
- Denmark
- Prior art keywords
- electrolyte layer
- layer
- range
- sensor device
- electrolyte
- Prior art date
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- 239000003792 electrolyte Substances 0.000 claims description 172
- 150000002500 ions Chemical class 0.000 claims description 23
- 239000008280 blood Substances 0.000 claims description 17
- 210000004369 blood Anatomy 0.000 claims description 17
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 16
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 15
- 229920001223 polyethylene glycol Polymers 0.000 claims description 8
- 229920000858 Cyclodextrin Polymers 0.000 claims description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical class OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 2
- 229940097362 cyclodextrins Drugs 0.000 claims description 2
- 150000002016 disaccharides Chemical class 0.000 claims description 2
- 150000004676 glycans Chemical class 0.000 claims description 2
- 150000002772 monosaccharides Chemical class 0.000 claims description 2
- 229920001542 oligosaccharide Polymers 0.000 claims description 2
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- -1 NaCI Chemical class 0.000 description 14
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Substances [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
- 229920001296 polysiloxane Polymers 0.000 description 11
- 239000000243 solution Substances 0.000 description 11
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 8
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- 235000002639 sodium chloride Nutrition 0.000 description 7
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 229910052697 platinum Inorganic materials 0.000 description 6
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- 238000012360 testing method Methods 0.000 description 5
- 229910000906 Bronze Inorganic materials 0.000 description 4
- 229920002535 Polyethylene Glycol 1500 Polymers 0.000 description 4
- 239000002202 Polyethylene glycol Substances 0.000 description 4
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 4
- 238000013459 approach Methods 0.000 description 4
- 239000010974 bronze Substances 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- KUNSUQLRTQLHQQ-UHFFFAOYSA-N copper tin Chemical compound [Cu].[Sn] KUNSUQLRTQLHQQ-UHFFFAOYSA-N 0.000 description 4
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- 230000000236 ionophoric effect Effects 0.000 description 4
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- 229910052700 potassium Inorganic materials 0.000 description 4
- 239000011591 potassium Substances 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 229910021607 Silver chloride Inorganic materials 0.000 description 3
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 3
- CFVBFMMHFBHNPZ-UHFFFAOYSA-N [Na].[V] Chemical compound [Na].[V] CFVBFMMHFBHNPZ-UHFFFAOYSA-N 0.000 description 3
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 3
- 229910021529 ammonia Inorganic materials 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 3
- 239000000919 ceramic Substances 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 239000004020 conductor Substances 0.000 description 3
- 230000018044 dehydration Effects 0.000 description 3
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- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 3
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- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- FPZWZCWUIYYYBU-UHFFFAOYSA-N 2-(2-ethoxyethoxy)ethyl acetate Chemical compound CCOCCOCCOC(C)=O FPZWZCWUIYYYBU-UHFFFAOYSA-N 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 238000004159 blood analysis Methods 0.000 description 2
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- 229920002678 cellulose Polymers 0.000 description 2
- 239000013626 chemical specie Substances 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 239000008393 encapsulating agent Substances 0.000 description 2
- 239000010408 film Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 238000006703 hydration reaction Methods 0.000 description 2
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- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
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- 239000013047 polymeric layer Substances 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 239000001103 potassium chloride Substances 0.000 description 2
- 235000011164 potassium chloride Nutrition 0.000 description 2
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
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- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- 239000004925 Acrylic resin Substances 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- MQIUGAXCHLFZKX-UHFFFAOYSA-N Di-n-octyl phthalate Natural products CCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCC MQIUGAXCHLFZKX-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 1
- GAMFEMAXLMWCRG-UHFFFAOYSA-N bis(dimethylcarbamothioylsulfanyl)arsanyl n,n-dimethylcarbamodithioate Chemical compound CN(C)C(=S)S[As](SC(=S)N(C)C)SC(=S)N(C)C GAMFEMAXLMWCRG-UHFFFAOYSA-N 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 150000003841 chloride salts Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229920002313 fluoropolymer Polymers 0.000 description 1
- 239000004811 fluoropolymer Substances 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 229910021485 fumed silica Inorganic materials 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
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- 230000002209 hydrophobic effect Effects 0.000 description 1
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- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- IIPYXGDZVMZOAP-UHFFFAOYSA-N lithium nitrate Inorganic materials [Li+].[O-][N+]([O-])=O IIPYXGDZVMZOAP-UHFFFAOYSA-N 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920001483 poly(ethyl methacrylate) polymer Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- 235000010333 potassium nitrate Nutrition 0.000 description 1
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- 229910052710 silicon Inorganic materials 0.000 description 1
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- 239000002002 slurry Substances 0.000 description 1
- 229910000693 sodium vanadium oxide Inorganic materials 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- YUYCVXFAYWRXLS-UHFFFAOYSA-N trimethoxysilane Chemical compound CO[SiH](OC)OC YUYCVXFAYWRXLS-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4925—Blood measuring blood gas content, e.g. O2, CO2, HCO3
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/304—Gas permeable electrodes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Ecology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Claims (13)
1. Planar C02-sensoranordning, der omfatter en elektrode (5) med et ionselektivt lag (8), et elektrolytlag (9) og et yderlag (10), hvor elektrolytlaget (9) er anbragt mellem det ionselektive lag (8) og yderlaget (10), og hvor elektrolytlaget (9) omfatter osmotisk aktive stoffer i en mængde på 0,8-6,0 milliosmol per m2 af elek-trolytlagområdet, kendetegnet ved, at elektrolytlaget (9) omfatter en hydrofil osmolaritetforøgende komponent, som ikke tilføjer bicarbonationer eller chloridioner til elektrolytlaget (9).
2. Sensoranordning ifølge krav 1, hvor den hydrofile osmolaritetforøgende komponent er til stede i elektrolytlaget (9) i en mængde i intervallet fra 0,05-1,2 millimol per m2 af elektrolytlagområde.
3. Sensoranordning ifølge hvilket som helst af kravene 1 eller 2, hvor elektrolytlaget (9) omfatter bicarbonationer i en mængde i intervallet fra 0,1-1,0 millimol per m2 af elektrolytlagområde.
4. Sensoranordning ifølge hvilke som helst af de foregående krav, hvor elektrolytlaget (9) omfatter chloridioner i en mængde i intervallet fra 0,05-1,0 millimol per m2 af elektrolytlagområde.
5. Sensoranordning ifølge krav 1, hvor elektrolytlaget (9) omfatter osmotisk aktive stoffer i en mængde på 0,8-2,5 milliosmol per m2af elektrolytlagområdet.
6. Sensoranordning ifølge krav 5, hvor den hydrofile osmolaritetforøgende komponent er til stede i elektrolytlaget (9) i en mængde i intervallet fra 0,05-0,5 millimol per m2 af elektrolytlagområde.
7. Sensoranordning ifølge hvilket som helst af kravene 5 eller 6, hvor elektrolytlaget (9) omfatter bicarbonationer i en mængde i intervallet fra 0,1-0,5 millimol per m2 af elektrolytlagområde.
8. Sensoranordning ifølge hvilket som helst af kravene 5-7, hvor elektrolytlaget (9) omfatter chloridioner i en mængde i intervallet fra 0,05-0,5 millimol per m2 af elektrolytlagområde.
9. Sensoranordning ifølge hvilke som helst af de foregående krav, hvor den hydrofile osmolaritetforøgende komponent har en vægtgennemsnitlig molekylvægt i intervallet fra 80-5.000 g/mol, fortrinsvis i intervallet fra 800-3.000 g/mol.
10. Sensoranordning ifølge krav 9, hvor den hydrofile osmolaritetforøgende komponent omfatter i det mindste en komponent, der er udvalgt fra gruppen, som består af oligo(ethylenglycoler), poly(ethylenglycoler), monosaccharider, disaccharider, oligosaccharider, polysaccharider og cyclodextriner. 11 Sensoranordning ifølge hvilke som helst af de foregående krav, hvor den hydrofile osmolaritetforøgende komponent bidrager med mere end 8 % til den samlede osmolaritet af elektrolytlaget (9).
12. Sensoranordning ifølge hvilke som helst af de foregående krav, hvor elektrolytlaget (9) har en tykkelse i intervallet fra 3-20 pm, fortrinsvis i intervallet fra 3-8 pm.
13. Sensoranordning ifølge hvilke som helst af de foregående krav, hvor elektrolytlaget (9) har en tykkelse i intervallet fra 3-20 pm, fortrinsvis i intervallet fra 3-8 pm, når det er i ligevægt med en standard human blodprøve.
14. Sensoranordning ifølge hvilke som helst af de foregående krav, hvor elektrolytlaget (9) omfatter osmotisk aktive stoffer med en osmolaritet på 300-350 mOsM.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200801828 | 2008-12-22 | ||
| PCT/DK2009/050347 WO2010072223A1 (en) | 2008-12-22 | 2009-12-18 | Planar sensor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2361380T3 true DK2361380T3 (da) | 2015-03-30 |
Family
ID=42104095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09804119T DK2361380T3 (da) | 2008-12-22 | 2009-12-18 | Planar sensor |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10060906B2 (da) |
| EP (1) | EP2361380B1 (da) |
| JP (1) | JP5300984B2 (da) |
| CN (2) | CN102326072B (da) |
| DK (1) | DK2361380T3 (da) |
| WO (1) | WO2010072223A1 (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2713877B1 (de) | 2011-05-23 | 2019-07-31 | Roche Diabetes Care GmbH | Sensorvorrichtung zum nachweis eines analyten |
| US9851328B2 (en) * | 2014-08-18 | 2017-12-26 | Stmicroelectronics Pte Ltd | Compact microelectronic integrated gas sensor |
| US10228343B2 (en) * | 2014-09-03 | 2019-03-12 | Northwestern University | Electrochemical detection of carbon dioxide using a carbohydrate based coordination polymer |
| EP3380833B1 (en) * | 2015-11-27 | 2019-12-25 | Radiometer Medical ApS | An outer layer for enzyme sensors |
| DK3394615T3 (da) | 2015-12-22 | 2023-11-27 | Radiometer Medical Aps | Fremgangsmåde til påvisning af tilstedeværelse eller fravær af et koagel i en væskeprøveanalysator |
| CN108431599B (zh) | 2015-12-22 | 2021-02-19 | 雷迪奥米特医学公司 | 检测液体样本分析仪中是否存在凝块的方法 |
| US10359391B2 (en) | 2016-07-07 | 2019-07-23 | e-SENS, Inc. | Sensor with a membrane having full circumferential adhesion |
| US10620151B2 (en) | 2016-08-30 | 2020-04-14 | Analog Devices Global | Electrochemical sensor, and a method of forming an electrochemical sensor |
| US11268927B2 (en) | 2016-08-30 | 2022-03-08 | Analog Devices International Unlimited Company | Electrochemical sensor, and a method of forming an electrochemical sensor |
| US12188893B2 (en) | 2016-08-30 | 2025-01-07 | Analog Devices International Unlimited Company | Electrochemical sensor, and a method of forming an electrochemical sensor |
| US10464063B2 (en) * | 2017-04-07 | 2019-11-05 | e-SENS, Inc. | Microfluidics chip with sensor die clamping structures |
| US10710068B2 (en) | 2017-09-20 | 2020-07-14 | e-SENSE, Inc. | Microfluidic chip with chemical sensor having back-side contacts |
| CN109839414A (zh) * | 2017-11-24 | 2019-06-04 | 英属开曼群岛商通润股份有限公司 | 阵列式感测电极及其制造方法与感测平台 |
| TW201925772A (zh) * | 2017-11-24 | 2019-07-01 | 英屬開曼群島商通潤股份有限公司 | 陣列式感測電極及其製造方法與感測平台 |
| US11022579B2 (en) | 2018-02-05 | 2021-06-01 | Analog Devices International Unlimited Company | Retaining cap |
| WO2020005692A1 (en) | 2018-06-29 | 2020-01-02 | Siemens Healthcare Diagnostics Inc. | Contoured sample path for fluid analyzer |
| US11609207B2 (en) * | 2020-03-31 | 2023-03-21 | Analog Devices International Unlimited Company | Electrochemical sensor and method of forming thereof |
| US11815487B2 (en) | 2020-11-11 | 2023-11-14 | Rosemount Inc. | Solid state reference gel |
| US12031938B2 (en) * | 2020-12-28 | 2024-07-09 | Rosemount Inc. | Gamma-irradiation-compatible reference gel |
| JP7588555B2 (ja) * | 2021-05-27 | 2024-11-22 | ローム株式会社 | 二酸化炭素ガスセンサ及びガスセンサ素子 |
| PL448894A1 (pl) * | 2024-06-19 | 2025-12-22 | Instytut Biocybernetyki I Inżynierii Biomedycznej Im. Macieja Nałęcza Polskiej Akademii Nauk | Planarna mikroelektroda jonoselektywna oraz sposób jej wytwarzania |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536274A (en) * | 1983-04-18 | 1985-08-20 | Diamond Shamrock Chemicals Company | pH and CO2 sensing device and method of making the same |
| US4818361A (en) | 1986-12-10 | 1989-04-04 | Diamond Sensor Systems | Combined pH and dissolved carbon dioxide gas sensor |
| GB8924159D0 (en) * | 1989-10-26 | 1989-12-13 | Morganite Electronic Instr | Sensors |
| JP2512843B2 (ja) * | 1991-09-24 | 1996-07-03 | 株式会社日立製作所 | 炭酸ガスセンサ |
| GB9405899D0 (en) * | 1994-03-24 | 1994-05-11 | Pima Sensors Inc | Gas sensor and sensing device |
| US5554272A (en) | 1995-08-10 | 1996-09-10 | Ciba Corning Diagnostics Corp. | Planar bicarbonate sensor |
| DK0889951T3 (da) * | 1996-03-29 | 2004-07-26 | Radiometer Medical As | Sensor og modificeret menbran til denne sensor |
| WO1997043634A1 (en) * | 1996-05-16 | 1997-11-20 | Sendx Medical, Inc. | Sensors with subminiature through holes, and method for fabricating such sensors |
| US6022463A (en) | 1996-05-16 | 2000-02-08 | Sendx Medical, Inc. | Sensors with subminiature through holes |
| US5858452A (en) | 1996-05-16 | 1999-01-12 | Sendx Medical, Inc. | Method for fabricating wiring substrate with subminiature thru-holes |
| JP3635263B2 (ja) * | 2000-03-01 | 2005-04-06 | ラジオメーター・メディカル・アクティーゼルスカブ | 固体状態参照系を持つ電極デバイス |
| CN1667407A (zh) * | 2004-03-11 | 2005-09-14 | 广州市中敏仪器有限公司 | 全固态二氧化碳电化学传感器 |
| EP1774324B1 (en) * | 2004-07-16 | 2013-02-27 | SensoCure AS | Electrochemical sensor for in-vivo or ex-vivo measurements of the carbon dioxide partial pressure of living tissue |
| KR20070052781A (ko) * | 2004-09-08 | 2007-05-22 | 앨러티스 메디칼 에이에스 | 센서 |
| TW200728714A (en) * | 2006-01-27 | 2007-08-01 | Univ Chung Yuan Christian | Potentiometric pCO2 sensor and the fabricating method thereof |
| TWI322007B (en) * | 2006-11-24 | 2010-03-21 | Health & Life Co Ltd | Biosensor, biostrip, and manufacture method of determination of uric acid by non-enzymatic reagent |
| US8241697B2 (en) * | 2007-12-20 | 2012-08-14 | Abbott Point Of Care Inc. | Formation of immobilized biological layers for sensing |
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| US10060906B2 (en) | 2018-08-28 |
| EP2361380A1 (en) | 2011-08-31 |
| CN102326072B (zh) | 2014-09-10 |
| CN104215671B (zh) | 2017-04-12 |
| JP2012513015A (ja) | 2012-06-07 |
| WO2010072223A1 (en) | 2010-07-01 |
| CN102326072A (zh) | 2012-01-18 |
| CN104215671A (zh) | 2014-12-17 |
| JP5300984B2 (ja) | 2013-09-25 |
| EP2361380B1 (en) | 2015-02-18 |
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