DK2365753T3 - Fremgangsmåde til fremstilling af deoxyribofuranoseforbindelser - Google Patents

Fremgangsmåde til fremstilling af deoxyribofuranoseforbindelser

Info

Publication number
DK2365753T3
DK2365753T3 DK09826915.2T DK09826915T DK2365753T3 DK 2365753 T3 DK2365753 T3 DK 2365753T3 DK 09826915 T DK09826915 T DK 09826915T DK 2365753 T3 DK2365753 T3 DK 2365753T3
Authority
DK
Denmark
Prior art keywords
preparing
procedure
deoxyribofuranose
compounds
deoxyribofuranose compounds
Prior art date
Application number
DK09826915.2T
Other languages
English (en)
Inventor
Gregory J Haley
Original Assignee
Anadys Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anadys Pharmaceuticals Inc filed Critical Anadys Pharmaceuticals Inc
Application granted granted Critical
Publication of DK2365753T3 publication Critical patent/DK2365753T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK09826915.2T 2008-11-17 2009-11-16 Fremgangsmåde til fremstilling af deoxyribofuranoseforbindelser DK2365753T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11513408P 2008-11-17 2008-11-17
PCT/US2009/064605 WO2010057103A1 (en) 2008-11-17 2009-11-16 Method of preparing deoxyribofuranose compounds

Publications (1)

Publication Number Publication Date
DK2365753T3 true DK2365753T3 (da) 2013-10-21

Family

ID=42170391

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09826915.2T DK2365753T3 (da) 2008-11-17 2009-11-16 Fremgangsmåde til fremstilling af deoxyribofuranoseforbindelser

Country Status (20)

Country Link
US (2) US8829168B2 (da)
EP (1) EP2365753B1 (da)
JP (1) JP5613168B2 (da)
KR (1) KR101643661B1 (da)
CN (1) CN102300464B (da)
AU (1) AU2009313842B2 (da)
BR (1) BRPI0922008A2 (da)
CA (1) CA2743796C (da)
DK (1) DK2365753T3 (da)
EA (1) EA020552B1 (da)
ES (1) ES2431269T3 (da)
IL (1) IL212902A0 (da)
MX (1) MX2011005170A (da)
MY (1) MY159745A (da)
NZ (1) NZ593021A (da)
PL (1) PL2365753T3 (da)
SI (1) SI2365753T1 (da)
TW (1) TWI450904B (da)
UA (1) UA103637C2 (da)
WO (1) WO2010057103A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX346131B (es) * 2010-12-29 2017-03-08 Akzo Nobel Coatings Int Bv Emulsiones de latex y composiciones de recubrimiento formadas a partir de las emulsiones de latex.
CN103172682B (zh) * 2013-03-14 2015-11-18 北京瑞博奥生物科技有限公司 2-脱氧-l-呋喃核糖的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69719673T2 (de) * 1996-05-16 2003-12-18 Taiho Pharmaceutical Co. Ltd., Tokio/Tokyo D-pentofuranose-derivate und verfahren zu ihrer herstellung
TR200601784T2 (tr) * 1999-11-12 2007-01-22 Pharmasset Ltd. 2'-deoksi-L-nükleositlerin sentezi
US6863782B2 (en) * 2002-11-15 2005-03-08 A.P. Pharma, Inc. Method of preparing di(ketene acetals)
US7034167B2 (en) * 2002-12-06 2006-04-25 Merck & Co., Inc. Process to ribofuranose sugar derivatives as intermediates to branched-chain nucleosides
EP1633711B1 (en) * 2003-06-17 2010-11-24 Schering Corporation Process and intermediates for the preparation of (1r,2s,5s)-6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylates or salts thereof
JP2007505070A (ja) * 2003-09-11 2007-03-08 エフ．ホフマン−ラ　ロシュ　アーゲー 抗ウイルス性ヌクレオシド誘導体を製造する方法
JP2007137843A (ja) * 2005-11-21 2007-06-07 Sumitomo Chemical Co Ltd リボフラノース化合物およびプリンヌクレオシド化合物の製造方法
US20070225246A1 (en) * 2006-03-27 2007-09-27 Denu John M O-acetyl-ADP-ribose non-hydrolyzable analogs
CN101172989B (zh) * 2006-11-03 2012-06-06 上海睿智化学研究有限公司 5-O-乙酰基-3-脱氧-1,2-异亚丙基-α-D-呋喃木糖的制备方法及一种中间体
MX2010007593A (es) * 2008-01-10 2010-10-13 Sun Pharma Advanced Res Co Ltd Derivados novedosos de acil cianopirrolidinas.

Also Published As

Publication number Publication date
BRPI0922008A2 (pt) 2016-05-10
AU2009313842B2 (en) 2015-08-20
IL212902A0 (en) 2011-07-31
CN102300464B (zh) 2014-11-12
EA201170702A1 (ru) 2011-12-30
US8829168B2 (en) 2014-09-09
AU2009313842A1 (en) 2010-05-20
KR101643661B1 (ko) 2016-07-28
JP2012509268A (ja) 2012-04-19
NZ593021A (en) 2013-04-26
MX2011005170A (es) 2011-05-30
PL2365753T3 (pl) 2013-12-31
CA2743796C (en) 2016-10-25
HK1162856A1 (en) 2012-09-07
JP5613168B2 (ja) 2014-10-22
CN102300464A (zh) 2011-12-28
US20140350231A1 (en) 2014-11-27
UA103637C2 (uk) 2013-11-11
TWI450904B (zh) 2014-09-01
KR20110084542A (ko) 2011-07-25
CA2743796A1 (en) 2010-05-20
US20110288282A1 (en) 2011-11-24
EP2365753A4 (en) 2012-07-04
ES2431269T3 (es) 2013-11-25
TW201028430A (en) 2010-08-01
EP2365753B1 (en) 2013-07-17
WO2010057103A1 (en) 2010-05-20
SI2365753T1 (sl) 2014-01-31
MY159745A (en) 2017-01-31
US9227992B2 (en) 2016-01-05
EP2365753A1 (en) 2011-09-21
EA020552B1 (ru) 2014-12-30

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