DK236690A - Bestatin gamma-form-krystal og fremgangsmaade til dens fremstilling - Google Patents
Bestatin gamma-form-krystal og fremgangsmaade til dens fremstilling Download PDFInfo
- Publication number
- DK236690A DK236690A DK236690A DK236690A DK236690A DK 236690 A DK236690 A DK 236690A DK 236690 A DK236690 A DK 236690A DK 236690 A DK236690 A DK 236690A DK 236690 A DK236690 A DK 236690A
- Authority
- DK
- Denmark
- Prior art keywords
- bestatin
- procedure
- manufacturing
- form crystal
- gamma form
- Prior art date
Links
- VGGGPCQERPFHOB-MCIONIFRSA-N Bestatin Chemical compound CC(C)C[C@H](C(O)=O)NC(=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1 VGGGPCQERPFHOB-MCIONIFRSA-N 0.000 title 1
- VGGGPCQERPFHOB-UHFFFAOYSA-N Bestatin Natural products CC(C)CC(C(O)=O)NC(=O)C(O)C(N)CC1=CC=CC=C1 VGGGPCQERPFHOB-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229950009811 ubenimex Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20814481 | 1981-12-24 | ||
| JP56208144A JPS58110553A (ja) | 1981-12-24 | 1981-12-24 | ベスタチンのγ型結晶及びその製造法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK236690D0 DK236690D0 (da) | 1990-10-01 |
| DK236690A true DK236690A (da) | 1990-10-01 |
| DK161972B DK161972B (da) | 1991-09-02 |
| DK161972C DK161972C (da) | 1992-02-03 |
Family
ID=16551358
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK545082A DK161094C (da) | 1981-12-24 | 1982-12-08 | Fremgangsmaade til fremstilling af bestatin gamma-form-krystal |
| DK236690A DK161972C (da) | 1981-12-24 | 1990-10-01 | Fremgangsmaade til fremstilling af bestatin gamma-form-krystal |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK545082A DK161094C (da) | 1981-12-24 | 1982-12-08 | Fremgangsmaade til fremstilling af bestatin gamma-form-krystal |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US4769490A (da) |
| JP (1) | JPS58110553A (da) |
| CH (1) | CH652727A5 (da) |
| CS (1) | CS236866B2 (da) |
| DE (1) | DE3246135C2 (da) |
| DK (2) | DK161094C (da) |
| ES (2) | ES518517A0 (da) |
| FR (1) | FR2518989B1 (da) |
| GB (1) | GB2111991B (da) |
| HU (1) | HU187831B (da) |
| IT (1) | IT1155439B (da) |
| NL (1) | NL8204951A (da) |
| SE (1) | SE453508B (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106631880B (zh) * | 2016-08-01 | 2018-06-01 | 四川青木制药有限公司 | 一种乌苯美司δ晶型及其制备方法 |
| CN113563221A (zh) * | 2018-07-09 | 2021-10-29 | 成都苑东生物制药股份有限公司 | 一种乌苯美司γ晶型的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4052449A (en) * | 1974-07-01 | 1977-10-04 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Biologically active substance, bestatin, and production thereof |
| JPS5439477B2 (da) * | 1974-07-01 | 1979-11-28 | ||
| US4189604A (en) * | 1975-07-22 | 1980-02-19 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Bestatin |
| GB1540019A (en) * | 1977-06-01 | 1979-02-07 | Microbial Chem Res Found | Bestatin derivatives |
| AR227636A1 (es) * | 1978-11-25 | 1982-11-30 | Nippon Kayaku Kk | Procedimiento para producir acido treo-3-amino-2-hidroxibutanoil aminoacetico intermediarios para prepararlo y procedimiento para preparar los intermediarios |
| JPS5767516A (en) * | 1980-09-24 | 1982-04-24 | Microbial Chem Res Found | Novel analgesic agent |
-
1981
- 1981-12-24 JP JP56208144A patent/JPS58110553A/ja active Granted
-
1982
- 1982-12-08 DK DK545082A patent/DK161094C/da not_active IP Right Cessation
- 1982-12-14 DE DE3246135A patent/DE3246135C2/de not_active Expired - Fee Related
- 1982-12-14 GB GB08235642A patent/GB2111991B/en not_active Expired
- 1982-12-22 SE SE8207338A patent/SE453508B/sv not_active IP Right Cessation
- 1982-12-22 CS CS829557A patent/CS236866B2/cs unknown
- 1982-12-22 IT IT24919/82A patent/IT1155439B/it active
- 1982-12-22 CH CH7507/82A patent/CH652727A5/de not_active IP Right Cessation
- 1982-12-22 NL NL8204951A patent/NL8204951A/nl not_active Application Discontinuation
- 1982-12-23 HU HU824158A patent/HU187831B/hu unknown
- 1982-12-23 ES ES518517A patent/ES518517A0/es active Granted
- 1982-12-23 FR FR8221680A patent/FR2518989B1/fr not_active Expired
-
1984
- 1984-03-15 ES ES530642A patent/ES530642A0/es active Granted
-
1987
- 1987-04-02 US US07/033,277 patent/US4769490A/en not_active Expired - Fee Related
- 1987-07-13 US US07/072,370 patent/US4786754A/en not_active Expired - Lifetime
-
1990
- 1990-10-01 DK DK236690A patent/DK161972C/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK236690D0 (da) | 1990-10-01 |
| GB2111991B (en) | 1985-06-26 |
| JPS6351145B2 (da) | 1988-10-13 |
| ES8405855A1 (es) | 1984-06-16 |
| ES8602618A1 (es) | 1985-12-16 |
| NL8204951A (nl) | 1983-07-18 |
| CH652727A5 (de) | 1985-11-29 |
| CS236866B2 (en) | 1985-05-15 |
| DE3246135A1 (de) | 1983-07-07 |
| FR2518989A1 (fr) | 1983-07-01 |
| DK161094C (da) | 1991-11-04 |
| US4769490A (en) | 1988-09-06 |
| DK545082A (da) | 1983-06-25 |
| ES518517A0 (es) | 1984-06-16 |
| DE3246135C2 (de) | 1995-11-30 |
| SE8207338L (sv) | 1983-06-25 |
| DK161094B (da) | 1991-05-27 |
| DK161972B (da) | 1991-09-02 |
| IT1155439B (it) | 1987-01-28 |
| ES530642A0 (es) | 1985-12-16 |
| SE453508B (sv) | 1988-02-08 |
| GB2111991A (en) | 1983-07-13 |
| US4786754A (en) | 1988-11-22 |
| JPS58110553A (ja) | 1983-07-01 |
| SE8207338D0 (sv) | 1982-12-22 |
| IT8224919A1 (it) | 1984-06-22 |
| HU187831B (en) | 1986-02-28 |
| FR2518989B1 (fr) | 1986-10-31 |
| DK161972C (da) | 1992-02-03 |
| IT8224919A0 (it) | 1982-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |