DK237086A - Cytostatisk virksomme titanocen-komplekser - Google Patents

Cytostatisk virksomme titanocen-komplekser Download PDF

Info

Publication number: DK237086A
Authority: DK; Denmark
Prior art keywords: titanocen; complexs; group; cytostatically effective; cooh
Prior art date: 1985-05-22

Application number

DK237086A

Other languages

English (en)

Other versions

DK237086D0 (da

Inventor

Petra Koepf-Maier

Hartmut Koepf

Original Assignee

Koepf Maier Petra

Hartmut Koepf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-22

Filing date

1986-05-21

Publication date

1986-11-23

1986-05-21 Application filed by Koepf Maier Petra, Hartmut Koepf filed Critical Koepf Maier Petra

1986-05-21 Publication of DK237086D0 publication Critical patent/DK237086D0/da

1986-11-23 Publication of DK237086A publication Critical patent/DK237086A/da

Links

125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
KOMDZQSPRDYARS-UHFFFAOYSA-N cyclopenta-1,3-diene titanium Chemical class [Ti].C1C=CC=C1.C1C=CC=C1 KOMDZQSPRDYARS-UHFFFAOYSA-N 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
150000003254 radicals Chemical class 0.000 abstract 1
229910052717 sulfur Chemical group 0.000 abstract 1
125000004434 sulfur atom Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Catalysts (AREA)

DK237086A 1985-05-22 1986-05-21 Cytostatisk virksomme titanocen-komplekser DK237086A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19853518447 DE3518447A1 (de)	1985-05-22	1985-05-22	Titanocen-komplexe und deren verwendung als cytostatica bei der krebsbekaempfung

Publications (2)

Publication Number	Publication Date
DK237086D0 DK237086D0 (da)	1986-05-21
DK237086A true DK237086A (da)	1986-11-23

Family

ID=6271383

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK237086A DK237086A (da)	1985-05-22	1986-05-21	Cytostatisk virksomme titanocen-komplekser

Country Status (9)

Country	Link
US (1)	US5002969A (da)
EP (1)	EP0202673B1 (da)
JP (1)	JPS61271294A (da)
AT (1)	ATE56018T1 (da)
DE (2)	DE3518447A1 (da)
DK (1)	DK237086A (da)
FI (1)	FI82941C (da)
IE (1)	IE59017B1 (da)
NO (1)	NO862006L (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3800760A1 (de) *	1988-01-13	1989-07-27	Koepf Maier Petra	Cytostatisch wirksame titanocen-derivate und diese enthaltende arzneimittel
DE3923270A1 (de) *	1989-07-14	1991-01-17	Medac Klinische Spezialpraep	Wasserloesliche pharmazeutische metallocen-komplex-zusammensetzung
DE4135291A1 (de) *	1991-10-25	1993-04-29	Koepf Maier Petra	Cytostatisch wirksame ionische metallocen-komplexe und diese komplexe enthaltende arzneimittel
US5496854A (en) *	1992-08-19	1996-03-05	Technion Research & Development Foundation Ltd.	Metallocenes as anti-tumor drugs
IL102866A (en) *	1992-08-19	1998-08-16	Technion Res & Dev Foundation	Metallocenes as anti-tumor drugs
HU212105B (en) *	1993-03-19	1996-02-28	Nitrokemia Ipartelepek	Process for producing titanium compounds of antitumor activiti and pharmaceutical compositions containing them
US6051603A (en) *	1998-01-20	2000-04-18	Wayne Hughes Institute	Vanadium (IV) metallocene complexes having sperm motility inhibiting activity
GB9929353D0 (en)	1999-12-13	2000-02-02	Univ Leeds	Metallocene synthesis
GB0215593D0 (en) *	2002-07-05	2002-08-14	Univ Leeds	New anticancer drugs
DE102006054690A1 (de) *	2006-11-17	2008-05-21	Charité - Universitätsmedizin Berlin	Carbonyl-substituierte Titanocene
JP2014516075A (ja)	2011-06-06	2014-07-07	シェブロンフィリップスケミカルカンパニーエルピー	癌治療のためのメタロセン化合物の使用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2923334C2 (de) *	1979-06-08	1985-03-07	Hartmut Prof. Dipl.-Chem. Dr. Köpf	Verwendung von Cyclopentadienylmetall-Acido-Komplexen bei der Krebsbekämpfung und diese Komplexe enthaltende Arzneipräparate

1985
- 1985-05-22 DE DE19853518447 patent/DE3518447A1/de not_active Withdrawn
1986
- 1986-05-21 AT AT86106912T patent/ATE56018T1/de not_active IP Right Cessation
- 1986-05-21 DK DK237086A patent/DK237086A/da not_active Application Discontinuation
- 1986-05-21 IE IE135186A patent/IE59017B1/en not_active IP Right Cessation
- 1986-05-21 DE DE8686106912T patent/DE3673692D1/de not_active Expired - Fee Related
- 1986-05-21 FI FI862132A patent/FI82941C/fi not_active IP Right Cessation
- 1986-05-21 NO NO862006A patent/NO862006L/no unknown
- 1986-05-21 EP EP86106912A patent/EP0202673B1/de not_active Expired - Lifetime
- 1986-05-22 JP JP61118381A patent/JPS61271294A/ja active Pending
- 1986-05-22 US US06/866,077 patent/US5002969A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE3673692D1 (de)	1990-10-04
FI862132L (fi)	1986-11-23
FI82941C (fi)	1991-05-10
FI82941B (fi)	1991-01-31
ATE56018T1 (de)	1990-09-15
US5002969A (en)	1991-03-26
EP0202673B1 (de)	1990-08-29
JPS61271294A (ja)	1986-12-01
FI862132A0 (fi)	1986-05-21
NO862006L (no)	1986-11-24
EP0202673A2 (de)	1986-11-26
IE59017B1 (en)	1993-12-15
DK237086D0 (da)	1986-05-21
DE3518447A1 (de)	1986-11-27
IE861351L (en)	1986-11-22
EP0202673A3 (en)	1987-03-25

Legal Events

Date	Code	Title	Description
1996-01-22	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
ES2061432T3 (es)	1994-12-16	Nuevas amidas de acido acrilico.
SE9301916D0 (sv)	1993-06-03	New peptides derivatives
DE69010139D1 (de)	1994-07-28	Haarkräftigungsmittel.
DK237086D0 (da)	1986-05-21	Cytostatisk virksomme titanocen-komplekser
FI852806L (fi)	1986-01-19	2-substituerade -1,3-propylidendifosfonatderivat och deras framstaellning.
DE3686022D1 (de)	1992-08-20	Monosaccharide enthaltende zusammensetzung zum heilen von wunden.
MY102991A (en)	1993-03-31	Medicaments for treating hypertension.
ATE119521T1 (de)	1995-03-15	Butenoinsäure-derivate.
AU575022B2 (en)	1988-07-21	Antiviral 5-halovinyl-2'-deoxyuridines
SE8601938L (sv)	1986-10-27	Handske
ES483270A1 (es)	1980-04-16	Un metodo de preparar benzamido-alcohil-mercaptanos
ATE56445T1 (de)	1990-09-15	Pharmacologisch aktive propionylanilide.
ES8704874A1 (es)	1987-05-01	Procedimiento de preparacion de nuevos derivados de acetilmetadol y de propoxifeno
JPS51151331A (en)	1976-12-25	Hydantoin series agricultural germicide