DK2404995T3 - Enzym associeret med equolsyntese - Google Patents

Enzym associeret med equolsyntese

Info

Publication number: DK2404995T3
Authority: DK; Denmark
Prior art keywords: equine; synthesis; enzyme associated; enzyme; equine synthesis
Prior art date: 2007-12-27

Application number

DK11170947.3T

Other languages

English (en)

Inventor

Yoshikazu Shimada

Setsuko Yasuda

Masayuki Takahashi

Takashi Hayashi

Norihiro Miyazawa

Yasuhiro Abiru

Original Assignee

Otsuka Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-12-27

Filing date

2008-12-25

Publication date

2013-10-14

2008-12-25 Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd

2013-10-14 Application granted granted Critical

2013-10-14 Publication of DK2404995T3 publication Critical patent/DK2404995T3/da

Links

102000004190 Enzymes Human genes 0.000 title 1
108090000790 Enzymes Proteins 0.000 title 1
241000283073 Equus caballus Species 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0073—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Enzymes And Modification Thereof (AREA)
Peptides Or Proteins (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

DK11170947.3T 2007-12-27 2008-12-25 Enzym associeret med equolsyntese DK2404995T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP2007336227		2007-12-27
JP2008054874		2008-03-05
JP2008080570		2008-03-26
EP08867315.7A EP2228441B1 (en)	2007-12-27	2008-12-25	Enzyme involved in synthesis of equol

Publications (1)

Publication Number	Publication Date
DK2404995T3 true DK2404995T3 (da)	2013-10-14

Family

ID=40824317

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK11170943.2T DK2404994T3 (da)	2007-12-27	2008-12-25	Enzym associeret med equolsyntese.
DK08867315.7T DK2228441T3 (da)	2007-12-27	2008-12-25	Enzym, der er involveret i syntese af equol.
DK11170947.3T DK2404995T3 (da)	2007-12-27	2008-12-25	Enzym associeret med equolsyntese

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
DK11170943.2T DK2404994T3 (da)	2007-12-27	2008-12-25	Enzym associeret med equolsyntese.
DK08867315.7T DK2228441T3 (da)	2007-12-27	2008-12-25	Enzym, der er involveret i syntese af equol.

Country Status (15)

Country	Link
US (4)	US8399232B2 (da)
EP (3)	EP2404995B1 (da)
JP (2)	JP5230654B2 (da)
KR (5)	KR20130133894A (da)
CN (5)	CN102676462A (da)
AR (1)	AR070058A1 (da)
CA (1)	CA2710812C (da)
DK (3)	DK2404994T3 (da)
ES (3)	ES2424960T3 (da)
MY (1)	MY156222A (da)
PT (3)	PT2228441E (da)
SG (2)	SG2013066642A (da)
SI (3)	SI2228441T1 (da)
TW (1)	TWI468516B (da)
WO (1)	WO2009084603A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2424960T3 (es) *	2007-12-27	2013-10-10	Otsuka Pharmaceutical Co., Ltd.	Enzima asociado a la síntesis de ecuol
CN102791876B (zh) *	2009-11-30	2016-06-08	细胞制药有限公司	新的7β-羟类固醇脱氢酶及它们的用途
CN118388581A (zh)	2013-03-08	2024-07-26	建新公司	治疗性蛋白药物物质的整合连续制造
JP6343899B2 (ja) *	2013-10-08	2018-06-20	東洋紡株式会社	黄色ブドウ球菌の検出方法
WO2015053061A1 (ja) *	2013-10-08	2015-04-16	東洋紡株式会社	メチシリン耐性遺伝子の検出方法および黄色ブドウ球菌の検出方法
TWI709569B (zh)	2014-01-17	2020-11-11	美商健臻公司	無菌層析樹脂及其用於製造方法的用途
TWI671312B (zh)	2014-01-17	2019-09-11	美商健臻公司	無菌層析法及製法
WO2017073753A1 (ja) *	2015-10-29	2017-05-04	株式会社ヤクルト本社	エコール産生能の測定方法
CN105861363B (zh) *	2016-04-15	2019-11-12	河北农业大学	爱格氏菌、s-雌马酚产生工程菌及其构建方法和应用
KR102005237B1 (ko) *	2017-02-28	2019-07-30	서울대학교산학협력단	에쿠올 유도체를 생산하는 재조합 대장균 및 이를 이용한 에쿠올 유도체 합성 방법
CN107641611B (zh) *	2017-06-29	2020-09-04	浙江省农业科学院	一种具有s-雌马酚抗性的大肠杆菌突变株及应用
JP2018186823A (ja) *	2018-07-13	2018-11-29	株式会社ダイセル	イソフラバノン類の製造方法
KR102079003B1 (ko) *	2018-08-10	2020-02-19	서울대학교산학협력단	활성이 증대된 테트라하이드로다이드제인 환원효소 및 에쿠올 유도체 생산에의 응용
BR112021003420A2 (pt)	2018-08-31	2021-05-18	Genzyme Corporation	resina cromatográfica estéril e uso da mesma em processos de manufatura
JP7469778B2 (ja)	2018-10-29	2024-04-17	一博舘田	エクオールを有効成分として含む腸内細菌に対する抗菌剤
CN112442490B (zh) *	2020-11-26	2022-03-01	湖南科技学院	一种转化酶及其在产s-雌马酚中的应用
US20240390432A1 (en) *	2021-09-30	2024-11-28	Board Of Regents, The University Of Texas System	Engineered vectors and organisms containing the same for isoflavone conversion in the gut
CN115747240B (zh) *	2022-08-05	2025-04-22	华熙生物科技股份有限公司	一种生产雌马酚的重组大肠杆菌工程菌株及应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6716424B1 (en) *	1997-08-08	2004-04-06	Otsuka Pharmaceutical Co., Ltd.	Streptococcus and isoflavone-containing composition
AUPQ008299A0 (en)	1999-04-30	1999-05-27	G.J. Consultants Pty Ltd	Isoflavone metabolites
JP4880859B2 (ja) *	2000-08-01	2012-02-22	株式会社カネカ	新規カルボニル還元酵素、その遺伝子、およびその利用法
US7416866B2 (en)	2002-02-01	2008-08-26	Schering Ag	Process for the overexpression of dehydrogenases
US7314974B2 (en) *	2002-02-21	2008-01-01	Monsanto Technology, Llc	Expression of microbial proteins in plants for production of plants with improved properties
EP1649760B1 (en)	2003-06-30	2013-05-22	Otsuka Pharmaceutical Co., Ltd.	Composition containing lactic acid bacterium producing equol
JP4610525B2 (ja)	2003-06-30	2011-01-12	大塚製薬株式会社	エクオール産生乳酸菌含有組成物
US7794993B2 (en) *	2004-08-06	2010-09-14	Kaneka Corporation	Carbonyl reductase, gene thereof and method of using the same
JP5222562B2 (ja) *	2005-11-02	2013-06-26	株式会社ヤクルト本社	エクオル濃度調節剤
EP2474237B1 (en) *	2005-12-06	2018-04-25	Otsuka Pharmaceutical Co., Ltd.	Equol-containing fermentation product of soybean embryonic axis, and method for production thereof
JP5005672B2 (ja)	2006-02-28	2012-08-22	株式会社カネカ	新規カルボニル還元酵素、その遺伝子、およびそれらを利用した光学活性アルコールの製造方法
ES2424960T3 (es) *	2007-12-27	2013-10-10	Otsuka Pharmaceutical Co., Ltd.	Enzima asociado a la síntesis de ecuol
JP5414368B2 (ja) *	2009-05-29	2014-02-12	大塚製薬株式会社	ジヒドロダイゼインをラセミ化する酵素

2008
- 2008-12-25 ES ES11170947T patent/ES2424960T3/es active Active
- 2008-12-25 US US12/810,742 patent/US8399232B2/en active Active
- 2008-12-25 KR KR1020137027981A patent/KR20130133894A/ko not_active Ceased
- 2008-12-25 PT PT88673157T patent/PT2228441E/pt unknown
- 2008-12-25 EP EP11170947.3A patent/EP2404995B1/en not_active Not-in-force
- 2008-12-25 SI SI200831018T patent/SI2228441T1/sl unknown
- 2008-12-25 ES ES08867315T patent/ES2423937T3/es active Active
- 2008-12-25 CA CA2710812A patent/CA2710812C/en active Active
- 2008-12-25 SG SG2013066642A patent/SG2013066642A/en unknown
- 2008-12-25 KR KR1020107016700A patent/KR101265400B1/ko active Active
- 2008-12-25 PT PT111709473T patent/PT2404995E/pt unknown
- 2008-12-25 ES ES11170943T patent/ES2424470T3/es active Active
- 2008-12-25 TW TW97150642A patent/TWI468516B/zh active
- 2008-12-25 KR KR1020127030667A patent/KR101543501B1/ko not_active Expired - Fee Related
- 2008-12-25 KR KR1020127030666A patent/KR101543500B1/ko not_active Expired - Fee Related
- 2008-12-25 SI SI200831028T patent/SI2404994T1/sl unknown
- 2008-12-25 DK DK11170943.2T patent/DK2404994T3/da active
- 2008-12-25 CN CN201210126502XA patent/CN102676462A/zh active Pending
- 2008-12-25 CN CN200880127246.8A patent/CN101952417B/zh active Active
- 2008-12-25 DK DK08867315.7T patent/DK2228441T3/da active
- 2008-12-25 WO PCT/JP2008/073649 patent/WO2009084603A1/ja not_active Ceased
- 2008-12-25 JP JP2009548072A patent/JP5230654B2/ja active Active
- 2008-12-25 KR KR1020137027968A patent/KR20130133893A/ko not_active Ceased
- 2008-12-25 CN CN2012101265354A patent/CN102676463A/zh active Pending
- 2008-12-25 DK DK11170947.3T patent/DK2404995T3/da active
- 2008-12-25 EP EP08867315.7A patent/EP2228441B1/en active Active
- 2008-12-25 SI SI200831033T patent/SI2404995T1/sl unknown
- 2008-12-25 CN CN2012101265049A patent/CN102703395A/zh active Pending
- 2008-12-25 EP EP11170943.2A patent/EP2404994B1/en not_active Not-in-force
- 2008-12-25 CN CN201510191176.4A patent/CN104830813A/zh active Pending
- 2008-12-25 PT PT111709432T patent/PT2404994E/pt unknown
- 2008-12-25 SG SG2013066634A patent/SG2013066634A/en unknown
- 2008-12-25 MY MYPI2010002883A patent/MY156222A/en unknown
- 2008-12-29 AR ARP080105754A patent/AR070058A1/es not_active Application Discontinuation
2012
- 2012-11-05 US US13/668,924 patent/US8669088B2/en active Active
- 2012-11-08 JP JP2012246695A patent/JP5689104B2/ja not_active Expired - Fee Related
2014
- 2014-01-15 US US14/155,557 patent/US8993296B2/en active Active
2015
- 2015-02-13 US US14/621,871 patent/US20150240275A1/en not_active Abandoned

Also Published As

Publication number	Publication date
TWI468516B (zh)	2015-01-11
US8669088B2 (en)	2014-03-11
US8399232B2 (en)	2013-03-19
PT2228441E (pt)	2013-08-27
JP5230654B2 (ja)	2013-07-10
CA2710812A1 (en)	2009-07-09
DK2404994T3 (da)	2013-09-08
PT2404994E (pt)	2013-09-25
CN101952417A (zh)	2011-01-19
PT2404995E (pt)	2013-09-26
EP2228441A4 (en)	2010-12-29
EP2404995B1 (en)	2013-07-17
BRPI0821816A2 (pt)	2014-10-14
JPWO2009084603A1 (ja)	2011-05-19
SG2013066634A (en)	2015-04-29
HK1166104A1 (en)	2012-10-19
US20130150568A1 (en)	2013-06-13
EP2228441B1 (en)	2013-06-19
CN102676462A (zh)	2012-09-19
AU2008344416A1 (en)	2009-07-09
HK1145189A1 (en)	2011-04-08
CN101952417B (zh)	2015-04-29
CA2710812C (en)	2018-06-05
SI2404995T1 (sl)	2013-10-30
KR20130006513A (ko)	2013-01-16
US20100330627A1 (en)	2010-12-30
CN102703395A (zh)	2012-10-03
KR20130008074A (ko)	2013-01-21
CN102676463A (zh)	2012-09-19
ES2424960T3 (es)	2013-10-10
US20140315264A1 (en)	2014-10-23
MY156222A (en)	2016-01-29
EP2404994A1 (en)	2012-01-11
WO2009084603A1 (ja)	2009-07-09
EP2404994B1 (en)	2013-07-03
ES2423937T3 (es)	2013-09-25
KR20130133893A (ko)	2013-12-09
JP5689104B2 (ja)	2015-03-25
HK1166103A1 (en)	2012-10-19
EP2404995A1 (en)	2012-01-11
JP2013051966A (ja)	2013-03-21
KR101265400B1 (ko)	2013-05-29
SI2228441T1 (sl)	2013-09-30
ES2424470T3 (es)	2013-10-02
KR101543500B1 (ko)	2015-08-11
SG2013066642A (en)	2015-04-29
CN104830813A (zh)	2015-08-12
AR070058A1 (es)	2010-03-10
DK2228441T3 (da)	2013-09-08
EP2228441A1 (en)	2010-09-15
US8993296B2 (en)	2015-03-31
SI2404994T1 (sl)	2013-10-30
TW200934868A (en)	2009-08-16
US20150240275A1 (en)	2015-08-27
KR20130133894A (ko)	2013-12-09
KR101543501B1 (ko)	2015-08-11
KR20100101161A (ko)	2010-09-16

Publication	Publication Date	Title
DK2404994T3 (da)	2013-09-08	Enzym associeret med equolsyntese.
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DK3196302T3 (da)	2020-09-14	Små enzymholdige granuler
DK2137307T3 (da)	2014-11-03	Termostabile asparaginaser
HRP20170963T1 (hr)	2017-09-22	Modificirani saharidi
EP2282708A4 (en)	2011-10-19	DRESSING
EP2315564A4 (en)	2013-02-20	WOUND DRESSING
BRPI0818348A2 (pt)	2015-04-07	Derivados de n-(pirazol-3-il)-benzamida como ativadores de glicocinase
BRPI1009115A2 (pt)	2015-10-06	ensaios de atividade de endopeptidase redirecionada imunobaseados
EP2187730A4 (en)	2011-05-11	GENETICALLY MODIFIED CHRYSANTHEMENTS
EP2280284A4 (en)	2014-10-29	Biosensor
EP2230301A4 (en)	2011-09-21	NEW GLUCOSE DEHYDROGENASE
EP2192402A4 (en)	2010-09-01	Enzyme electrode
IT1390861B1 (it)	2011-10-19	Composti ad attività antimalarica
IT1391693B1 (it)	2012-01-17	Letto
EP2202304A4 (en)	2010-11-24	MODIFIED CREATININE AMIDOHYDROLASE
FI20070190A0 (fi)	2007-03-05	Bioreaktori
EP2195338A4 (en)	2010-11-03	N-TERMINAL MODIFIED INTERFERON ALPHA
SE0701964L (sv)	2009-03-04	Stödgördel
DK1910527T3 (da)	2013-03-25	Maltose-1-phosphat producerende enzym
DE112008000355A5 (de)	2009-11-19	Schreibunterlage
TH96487B (th)	2009-07-09	เตียง
UA17009S (uk)	2008-07-25	Ліжко
TH96486B (th)	2009-07-09	เตียง