DK243589A - Fremgangsmaade til fremstilling af human-vaevstypeplasminogenaktivator - Google Patents

Fremgangsmaade til fremstilling af human-vaevstypeplasminogenaktivator Download PDF

Info

Publication number: DK243589A
Authority: DK; Denmark
Prior art keywords: tpa; plasminogen activator; medium; textile; manufacturing human
Prior art date: 1988-05-19

Application number

DK243589A

Other languages

English (en)

Other versions

DK243589D0 (da

Inventor

Shyoichiro Miyahara

Maki Suzuki

Atsunori Shindo

Nobumi Kusuhara

Nobuyoshi Makiguchi

Original Assignee

Mitsui Toatsu Chemicals

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-05-19

Filing date

1989-05-19

Publication date

1989-11-20

1988-05-19 Priority claimed from JP12264488A external-priority patent/JP2648611B2/ja

1988-12-16 Priority claimed from JP63316118A external-priority patent/JP2718726B2/ja

1989-05-19 Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals

1989-05-19 Publication of DK243589D0 publication Critical patent/DK243589D0/da

1989-11-20 Publication of DK243589A publication Critical patent/DK243589A/da

Links

238000000034 method Methods 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title abstract 2
102000001938 Plasminogen Activators Human genes 0.000 title 1
108010001014 Plasminogen Activators Proteins 0.000 title 1
229940127126 plasminogen activator Drugs 0.000 title 1
239000004753 textile Substances 0.000 title 1
239000002609 medium Substances 0.000 abstract 3
101000801481 Homo sapiens Tissue-type plasminogen activator Proteins 0.000 abstract 1
QCTBMLYLENLHLA-UHFFFAOYSA-N aminomethylbenzoic acid Chemical class NCC1=CC=C(C(O)=O)C=C1 QCTBMLYLENLHLA-UHFFFAOYSA-N 0.000 abstract 1
239000006143 cell culture medium Substances 0.000 abstract 1
230000003204 osmotic effect Effects 0.000 abstract 1
239000013589 supplement Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Cell Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

DK243589A 1988-05-19 1989-05-19 Fremgangsmaade til fremstilling af human-vaevstypeplasminogenaktivator DK243589A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP12264488A JP2648611B2 (ja)	1988-05-19	1988-05-19	ヒト組織型プラスミノーゲン活性化因子の製法
JP63316118A JP2718726B2 (ja)	1988-12-16	1988-12-16	ヒト組織型プラスミノーゲン活性化因子の製法

Publications (2)

Publication Number	Publication Date
DK243589D0 DK243589D0 (da)	1989-05-19
DK243589A true DK243589A (da)	1989-11-20

Family

ID=26459739

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK243589A DK243589A (da)	1988-05-19	1989-05-19	Fremgangsmaade til fremstilling af human-vaevstypeplasminogenaktivator

Country Status (10)

Country	Link
US (1)	US5151359A (da)
EP (1)	EP0342931B1 (da)
AT (1)	ATE108825T1 (da)
AU (1)	AU612837B2 (da)
CA (1)	CA1334288C (da)
DE (1)	DE68916857T2 (da)
DK (1)	DK243589A (da)
FI (1)	FI98123C (da)
NO (1)	NO175541C (da)
NZ (1)	NZ229187A (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5183754A (en) *	1988-10-04	1993-02-02	Mitsui Toatsu Chemicals, Incorporated	Method for production of human tissue type plasminogen activator
EP0756003B1 (en) *	1994-02-18	1999-03-24	Teijin Limited	Method of culturing animal cells
US5856179A (en) *	1994-03-10	1999-01-05	Genentech, Inc.	Polypeptide production in animal cell culture
US5721121A (en) *	1995-06-06	1998-02-24	Genentech, Inc.	Mammalian cell culture process for producing a tumor necrosis factor receptor immunoglobulin chimeric protein
US6656466B1 (en)	1995-06-06	2003-12-02	Genetech, Inc.	Human tumor necrosis factor—immunoglobulin(TNFR1-IgG1) chimera composition
US5705364A (en) *	1995-06-06	1998-01-06	Genentech, Inc.	Mammalian cell culture process
WO2002101019A2 (en) *	2001-06-13	2002-12-19	Genentech, Inc.	Methods of culturing animal cells and polypeptide production in animal cells
WO2012122625A1 (en)	2011-03-14	2012-09-20	National Research Council Of Canada	Method of viral production in cells

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3732146A (en) *	1970-12-22	1973-05-08	Behringwerke Ag	Process for the isolation of native, highly purified plasminogen
JPS59196824A (ja) *	1983-04-21	1984-11-08	Kowa Co	吸着防止剤
FR2548211B1 (fr) *	1983-06-29	1985-10-18	Choay Sa	Procede de production d'un activateur tissulaire du plasminogene et activateur obtenu par ce procede
US4554251A (en) *	1983-11-07	1985-11-19	The Ohio State University Research Foundation	Process and medium for culturing ant venom gland cells
GB8334499D0 (en) *	1983-12-24	1984-02-01	Beecham Group Plc	Derivatives
US4724206A (en) *	1984-02-13	1988-02-09	Damon Biotech, Inc.	Protein production using hypertonic media
EP0163751B1 (en) *	1984-06-05	1989-09-20	Asahi Kasei Kogyo Kabushiki Kaisha	Process for the preparation of a plasminogen activator
US4661453A (en) *	1984-06-19	1987-04-28	American Biogenetic Sciences, Inc.	Production of tissue plasminogen activator factor
US4661469A (en) *	1984-08-08	1987-04-28	Survival Technology, Inc.	t-PA composition capable of being absorbed into the blood stream and method of administration
JPS624233A (ja) *	1985-07-01	1987-01-10	Toyobo Co Ltd	組織性プラスミノ−ゲン活性化因子の製造法
US4960702A (en) *	1985-09-06	1990-10-02	Codon	Methods for recovery of tissue plasminogen activator
US5183754A (en) *	1988-10-04	1993-02-02	Mitsui Toatsu Chemicals, Incorporated	Method for production of human tissue type plasminogen activator

1989
- 1989-05-05 US US07/347,649 patent/US5151359A/en not_active Expired - Fee Related
- 1989-05-09 CA CA000599119A patent/CA1334288C/en not_active Expired - Fee Related
- 1989-05-16 EP EP89304944A patent/EP0342931B1/en not_active Expired - Lifetime
- 1989-05-16 DE DE68916857T patent/DE68916857T2/de not_active Expired - Fee Related
- 1989-05-16 AT AT89304944T patent/ATE108825T1/de not_active IP Right Cessation
- 1989-05-17 FI FI892358A patent/FI98123C/fi not_active IP Right Cessation
- 1989-05-17 AU AU34892/89A patent/AU612837B2/en not_active Ceased
- 1989-05-18 NO NO891995A patent/NO175541C/no unknown
- 1989-05-18 NZ NZ229187A patent/NZ229187A/en unknown
- 1989-05-19 DK DK243589A patent/DK243589A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
FI892358L (fi)	1989-11-20
EP0342931B1 (en)	1994-07-20
DE68916857T2 (de)	1994-11-10
DK243589D0 (da)	1989-05-19
FI98123C (fi)	1997-04-25
DE68916857D1 (de)	1994-08-25
CA1334288C (en)	1995-02-07
NO891995L (no)	1989-11-20
AU3489289A (en)	1989-11-23
US5151359A (en)	1992-09-29
NO891995D0 (no)	1989-05-18
FI892358A0 (fi)	1989-05-17
NO175541C (no)	1994-10-26
FI98123B (fi)	1997-01-15
EP0342931A1 (en)	1989-11-23
NZ229187A (en)	1991-12-23
AU612837B2 (en)	1991-07-18
NO175541B (no)	1994-07-18
ATE108825T1 (de)	1994-08-15

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Legal Events

Date	Code	Title	Description
2003-01-06	AHB	Application shelved due to non-payment