DK2510085T3 - Vokenstamcelle-afledt konditioneret medium og/eller voksenstamceller til anvendelse i den terapeutiske behandling af en tumorsygdom - Google Patents

Vokenstamcelle-afledt konditioneret medium og/eller voksenstamceller til anvendelse i den terapeutiske behandling af en tumorsygdom Download PDF

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Publication number
DK2510085T3
DK2510085T3 DK10788321.7T DK10788321T DK2510085T3 DK 2510085 T3 DK2510085 T3 DK 2510085T3 DK 10788321 T DK10788321 T DK 10788321T DK 2510085 T3 DK2510085 T3 DK 2510085T3
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Denmark
Prior art keywords
adult stem
therapeutic treatment
conditioned medium
tumor disease
stem cells
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DK10788321.7T
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English (en)
Inventor
Sanchez Maria Beatriz Herrera
Valentina Fonsato
Ciro Tetta
Giovanni Camussi
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Fresenius Medical Care Deutschland Gmbh
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Application filed by Fresenius Medical Care Deutschland Gmbh filed Critical Fresenius Medical Care Deutschland Gmbh
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Publication of DK2510085T3 publication Critical patent/DK2510085T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C12N2500/84—Undefined extracts from animals from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/14—Coculture with; Conditioned medium produced by hepatocytes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK10788321.7T 2009-12-09 2010-12-07 Vokenstamcelle-afledt konditioneret medium og/eller voksenstamceller til anvendelse i den terapeutiske behandling af en tumorsygdom DK2510085T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09425504A EP2333047A1 (en) 2009-12-09 2009-12-09 Adult stem cell derived conditioned medium and/or adult stem cells for use in the therapeutic treatment of a tumor disease
PCT/EP2010/069049 WO2011070001A1 (en) 2009-12-09 2010-12-07 Adult stem cell derived conditioned medium and/or adult stem cells for use in the therapeutic treatment of a tumor disease

Publications (1)

Publication Number Publication Date
DK2510085T3 true DK2510085T3 (da) 2019-10-14

Family

ID=42111703

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10788321.7T DK2510085T3 (da) 2009-12-09 2010-12-07 Vokenstamcelle-afledt konditioneret medium og/eller voksenstamceller til anvendelse i den terapeutiske behandling af en tumorsygdom

Country Status (9)

Country Link
US (1) US9034335B2 (da)
EP (2) EP2333047A1 (da)
JP (1) JP5788405B2 (da)
CN (1) CN102686723B (da)
DK (1) DK2510085T3 (da)
ES (1) ES2752348T3 (da)
PL (1) PL2510085T3 (da)
PT (1) PT2510085T (da)
WO (1) WO2011070001A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2906750T3 (es) 2010-05-12 2022-04-20 Prokidney Células renales bioactivas
US9347953B2 (en) * 2010-12-06 2016-05-24 Thd S.P.A. Method for the diagnosis of a carcinoma and uses thereof
WO2013121426A1 (en) 2012-02-13 2013-08-22 Gamida-Cell Ltd. Culturing of mesenchymal stem cells
CN103387959A (zh) * 2012-10-19 2013-11-13 夏佑红 一种乳牙干细胞及其制备方法和应用
CN104099294A (zh) * 2013-04-03 2014-10-15 北京京蒙高科干细胞技术有限公司 基于干细胞分泌因子的培养基及其制备和使用方法
IN2013MU02045A (da) * 2013-06-17 2015-06-05 Kasiak Res Pvt Ltd
JP6474394B2 (ja) 2013-07-05 2019-02-27 ユニベルシテ カトリック ドゥ ルーベン ヒト成体肝臓幹細胞由来の馴化培地および肝臓障害の治療におけるその使用
KR102297734B1 (ko) * 2014-01-24 2021-09-03 가부시키가이샤 쿠오리맨 앤 코. 암 치료용 의약 조성물 및 그 조성물을 유효 성분으로 하는 암 치료용 의약 제제
RU2644650C2 (ru) 2014-12-01 2018-02-13 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток и способ его получения
CN109104869B (zh) * 2016-04-27 2022-07-01 日本乐敦制药株式会社 表达细胞表面标记物的间充质干细胞、包含该间充质干细胞的药物组合物及其制备方法
RU2708329C2 (ru) 2016-05-31 2019-12-05 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток, композиции и способы применения
ES3042057T3 (en) * 2016-08-26 2025-11-18 Restem Llc Composition and methods of using umbilical cord lining stem cells
CA3085662A1 (en) 2017-12-14 2019-06-20 Unicyte Ev Ag Pharmaceutical carriers containing mirnas for use in the treatment of renal cancer
WO2019142028A1 (en) 2018-01-19 2019-07-25 Mehrdad Noruzinia Conditioned stem cell-derived extract
AU2019416339A1 (en) * 2018-12-26 2021-07-22 Direct Biologics Llc Methods and compositions for treating skin and hair disorders
CN111454892A (zh) * 2020-03-12 2020-07-28 成都世联康健生物科技有限公司 牙间充质干细胞培养基及在牙髓干细胞内的活性验证方法
US20230313144A1 (en) * 2020-09-03 2023-10-05 Jichi Medical University Detoxified secretome extract made from culture supernatant of mesenchymal stem cells or progenitor cells derived from the mesenchymal stem cells, and method for producing same
CA3214688A1 (en) * 2021-04-08 2022-10-13 Andrzej KROLEWSKI Methods of diagnosing and predicting renal decline

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005205240B2 (en) * 2004-01-14 2011-04-21 Novahep Ab Human hepatic progenitor cells and methods of use thereof
WO2006126219A1 (en) 2005-05-26 2006-11-30 Fresenius Medical Care Deutschland G.M.B.H. Liver progenitor cells
WO2008020815A1 (en) * 2006-08-15 2008-02-21 Agency For Science, Technology And Research Mesenchymal stem cell conditioned medium
ES2359874T5 (es) * 2005-12-21 2014-12-12 Universite Catholique De Louvain Células madre hepáticas aisladas
US7993918B2 (en) * 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
PT2254586E (pt) 2008-02-22 2015-05-18 Agency Science Tech & Res Partículas de células estaminais mesenquimais
CN102119031B (zh) * 2008-06-11 2014-09-10 弗雷森纽斯医疗护理德国有限责任公司 肝祖细胞的条件培养基

Also Published As

Publication number Publication date
EP2510085B1 (en) 2019-08-07
JP5788405B2 (ja) 2015-09-30
WO2011070001A1 (en) 2011-06-16
ES2752348T3 (es) 2020-04-06
PL2510085T3 (pl) 2020-01-31
CN102686723B (zh) 2016-11-23
EP2510085A1 (en) 2012-10-17
US9034335B2 (en) 2015-05-19
US20120251489A1 (en) 2012-10-04
EP2333047A1 (en) 2011-06-15
PT2510085T (pt) 2019-10-30
CN102686723A (zh) 2012-09-19
JP2013513366A (ja) 2013-04-22

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