DK2510085T3 - Vokenstamcelle-afledt konditioneret medium og/eller voksenstamceller til anvendelse i den terapeutiske behandling af en tumorsygdom - Google Patents

Vokenstamcelle-afledt konditioneret medium og/eller voksenstamceller til anvendelse i den terapeutiske behandling af en tumorsygdom Download PDF

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Publication number
DK2510085T3
DK2510085T3 DK10788321.7T DK10788321T DK2510085T3 DK 2510085 T3 DK2510085 T3 DK 2510085T3 DK 10788321 T DK10788321 T DK 10788321T DK 2510085 T3 DK2510085 T3 DK 2510085T3
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adult stem
therapeutic treatment
conditioned medium
tumor disease
stem cells
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DK10788321.7T
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English (en)
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Sanchez Maria Beatriz Herrera
Valentina Fonsato
Ciro Tetta
Giovanni Camussi
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Fresenius Medical Care Deutschland Gmbh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C12N2500/84—Undefined extracts from animals from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/14—Coculture with; Conditioned medium produced by hepatocytes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK10788321.7T 2009-12-09 2010-12-07 Vokenstamcelle-afledt konditioneret medium og/eller voksenstamceller til anvendelse i den terapeutiske behandling af en tumorsygdom DK2510085T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09425504A EP2333047A1 (en) 2009-12-09 2009-12-09 Adult stem cell derived conditioned medium and/or adult stem cells for use in the therapeutic treatment of a tumor disease
PCT/EP2010/069049 WO2011070001A1 (en) 2009-12-09 2010-12-07 Adult stem cell derived conditioned medium and/or adult stem cells for use in the therapeutic treatment of a tumor disease

Publications (1)

Publication Number Publication Date
DK2510085T3 true DK2510085T3 (da) 2019-10-14

Family

ID=42111703

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10788321.7T DK2510085T3 (da) 2009-12-09 2010-12-07 Vokenstamcelle-afledt konditioneret medium og/eller voksenstamceller til anvendelse i den terapeutiske behandling af en tumorsygdom

Country Status (9)

Country Link
US (1) US9034335B2 (da)
EP (2) EP2333047A1 (da)
JP (1) JP5788405B2 (da)
CN (1) CN102686723B (da)
DK (1) DK2510085T3 (da)
ES (1) ES2752348T3 (da)
PL (1) PL2510085T3 (da)
PT (1) PT2510085T (da)
WO (1) WO2011070001A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102539589B1 (ko) 2010-05-12 2023-06-01 인리젠 생물활성 신장 세포
EP2649445B1 (en) 2010-12-06 2015-05-06 THD S.p.A. Method for the diagnosis of a carcinoma
EP2814950A1 (en) 2012-02-13 2014-12-24 Gamida-Cell Ltd. Mesenchymal stem cells conditioned medium and methods of generating and using the same
CN103387959A (zh) * 2012-10-19 2013-11-13 夏佑红 一种乳牙干细胞及其制备方法和应用
CN104099294A (zh) * 2013-04-03 2014-10-15 北京京蒙高科干细胞技术有限公司 基于干细胞分泌因子的培养基及其制备和使用方法
WO2014203267A2 (en) * 2013-06-17 2014-12-24 Kasiak Research Pvt. Ltd. Method for isolation, purification and industrial scale expansion of human adipose tissue derived mesenchymal stem cells
WO2015001124A1 (en) 2013-07-05 2015-01-08 Université Catholique de Louvain Conditioned medium from human adult liver stem cells and its use in the treatment of liver disorders
SG11201605868XA (en) * 2014-01-24 2016-08-30 Quarrymen Corp Pharmaceutical composition for cancer treatment and pharmaceutical preparation for cancer treatment containing same composition as active ingredient
RU2644650C2 (ru) 2014-12-01 2018-02-13 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток и способ его получения
JP7108537B2 (ja) * 2016-04-27 2022-07-28 ロート製薬株式会社 Ｃｄ２０１、ｃｄ４６、ｃｄ５６、ｃｄ１４７及びｃｄ１６５からなる群より選択される少なくとも１種の細胞表面マーカーを発現する間葉系幹細胞及びその調製方法、並びに上記間葉系幹細胞を含む医薬組成物及びその調製方法
RU2708329C2 (ru) 2016-05-31 2019-12-05 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток, композиции и способы применения
EP4600348A3 (en) * 2016-08-26 2025-12-10 Restem Llc Composition and methods of using umbilical cord lining stem cells
CA3085662A1 (en) 2017-12-14 2019-06-20 Unicyte Ev Ag Pharmaceutical carriers containing mirnas for use in the treatment of renal cancer
WO2019142028A1 (en) 2018-01-19 2019-07-25 Mehrdad Noruzinia Conditioned stem cell-derived extract
JOP20210170A1 (ar) * 2018-12-26 2023-01-30 Direct Biologics Llc طرق وتركيبات لعلاج اضطرابات الجلد والشعر
CN111454892A (zh) * 2020-03-12 2020-07-28 成都世联康健生物科技有限公司 牙间充质干细胞培养基及在牙髓干细胞内的活性验证方法
JP2022043013A (ja) * 2020-09-03 2022-03-15 学校法人自治医科大学 間葉系幹細胞又はそれに由来する前駆細胞の培養上清の浄化濃縮物、及びその製造方法
JP2024516548A (ja) * 2021-04-08 2024-04-16 ジョスリン ダイアビーティス センター インコーポレイテッド 腎機能低下の診断及び予測の方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060040386A1 (en) * 2004-01-14 2006-02-23 Suchitra Holgersson Human hepatic progenitor cells and methods of use thereof
WO2006126219A1 (en) 2005-05-26 2006-11-30 Fresenius Medical Care Deutschland G.M.B.H. Liver progenitor cells
CN101356264B (zh) * 2005-12-21 2014-05-14 鲁汶大学 分离的肝脏干细胞
US7993918B2 (en) * 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
EP2617428A1 (en) * 2006-08-15 2013-07-24 Agency for Science, Technology and Research Mesenchymal stem cell conditioned medium
JP5718648B2 (ja) * 2008-02-22 2015-05-13 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ（エイ・スター） 間葉系幹細胞粒子
BRPI0909866B1 (pt) * 2008-06-11 2021-08-24 Fresenius Medical Care Deutschland Gmbh Método de produção de um meio condicionado de células progenitoras de fígado, meio condicionado e composição farmacêutica

Also Published As

Publication number Publication date
EP2510085B1 (en) 2019-08-07
US20120251489A1 (en) 2012-10-04
WO2011070001A1 (en) 2011-06-16
ES2752348T3 (es) 2020-04-06
EP2333047A1 (en) 2011-06-15
US9034335B2 (en) 2015-05-19
PT2510085T (pt) 2019-10-30
CN102686723A (zh) 2012-09-19
JP5788405B2 (ja) 2015-09-30
PL2510085T3 (pl) 2020-01-31
JP2013513366A (ja) 2013-04-22
CN102686723B (zh) 2016-11-23
EP2510085A1 (en) 2012-10-17

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