DK2528602T4 - Formuleringer af bendamustin - Google Patents

Formuleringer af bendamustin Download PDF

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Publication number
DK2528602T4
DK2528602T4 DK11737745.7T DK11737745T DK2528602T4 DK 2528602 T4 DK2528602 T4 DK 2528602T4 DK 11737745 T DK11737745 T DK 11737745T DK 2528602 T4 DK2528602 T4 DK 2528602T4
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DK
Denmark
Prior art keywords
bendamustin
formulations
Prior art date
Application number
DK11737745.7T
Other languages
English (en)
Other versions
DK2528602T3 (da
Inventor
Nagesh R Palepu
Philip Christopher Buxton
Original Assignee
Eagle Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44309429&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2528602(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eagle Pharmaceuticals Inc filed Critical Eagle Pharmaceuticals Inc
Application granted granted Critical
Publication of DK2528602T3 publication Critical patent/DK2528602T3/da
Publication of DK2528602T4 publication Critical patent/DK2528602T4/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK11737745.7T 2010-01-28 2011-01-28 Formuleringer af bendamustin DK2528602T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29910010P 2010-01-28 2010-01-28
PCT/US2011/022958 WO2011094565A1 (en) 2010-01-28 2011-01-28 Formulations of bendamustine

Publications (2)

Publication Number Publication Date
DK2528602T3 DK2528602T3 (da) 2017-01-23
DK2528602T4 true DK2528602T4 (da) 2020-04-27

Family

ID=44309429

Family Applications (2)

Application Number Title Priority Date Filing Date
DK16020363.4T DK3158991T3 (da) 2010-01-28 2011-01-28 Formuleringer af bendamustin
DK11737745.7T DK2528602T4 (da) 2010-01-28 2011-01-28 Formuleringer af bendamustin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK16020363.4T DK3158991T3 (da) 2010-01-28 2011-01-28 Formuleringer af bendamustin

Country Status (16)

Country Link
US (17) US8609707B2 (da)
EP (3) EP2528602B2 (da)
JP (2) JP5795600B2 (da)
CA (1) CA2787568C (da)
CY (2) CY1118769T1 (da)
DK (2) DK3158991T3 (da)
ES (2) ES2609106T5 (da)
HR (2) HRP20161771T4 (da)
HU (2) HUE054836T2 (da)
LT (2) LT3158991T (da)
PL (2) PL3158991T3 (da)
PT (2) PT2528602T (da)
RS (2) RS55491B2 (da)
SI (2) SI2528602T2 (da)
SM (3) SMT202100348T1 (da)
WO (1) WO2011094565A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
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ES2609106T5 (es) 2010-01-28 2020-11-10 Eagle Pharmaceuticals Inc Formulaciones de bendamustina
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DK3533447T3 (da) * 2012-03-20 2023-04-24 Eagle Pharmaceuticals Inc Flydende bendamustinsammensætninger til anvendelse i fremgangsmåde til behandling af bendamustin-responsive tilstande hos patienter som kræver reducerede volumener til indgivelse
FI2827862T3 (fi) * 2012-03-20 2024-02-13 Eagle Pharmaceuticals Inc Bendamustiinin formulaatioita
CN105491886B (zh) 2013-08-27 2019-01-29 V·沃道里斯 苯达莫司汀医药组合物
JP5856264B2 (ja) * 2013-09-20 2016-02-09 参天製薬株式会社 ポリエチレングリコール含有組成物
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JP2020090481A (ja) * 2018-11-27 2020-06-11 日本化薬株式会社 ベンダムスチンを含有する溶液製剤
JP7235288B2 (ja) * 2019-01-07 2023-03-08 コーアイセイ株式会社 ベンダムスチンの液体製剤
WO2020170104A1 (en) * 2019-02-18 2020-08-27 Shilpa Medicare Limited Liquid bendamustine parenteral compositions
JPWO2021161876A1 (da) * 2020-02-10 2021-08-19
CA3145107A1 (en) * 2020-04-09 2021-10-14 Yue Jing Bendamustine and cyclodextrin composition and use thereof
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US11707450B1 (en) * 2022-03-03 2023-07-25 Slayback Pharma Llc Stable pharmaceutical compositions of bendamustine

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Also Published As

Publication number Publication date
EP2528602A4 (en) 2014-01-22
US20160143888A1 (en) 2016-05-26
SMT201700043T1 (it) 2017-03-08
LT3158991T (lt) 2021-07-12
EP3158991A1 (en) 2017-04-26
US9572796B2 (en) 2017-02-21
US20180296535A1 (en) 2018-10-18
HRP20161771T4 (hr) 2020-08-07
SI2528602T1 (sl) 2017-03-31
US20240293373A1 (en) 2024-09-05
US11844783B2 (en) 2023-12-19
US9265831B2 (en) 2016-02-23
WO2011094565A1 (en) 2011-08-04
EP2528602A1 (en) 2012-12-05
EP2528602B1 (en) 2016-10-05
CA2787568C (en) 2019-04-02
US12350257B2 (en) 2025-07-08
US11103483B2 (en) 2021-08-31
SMT201700043B (it) 2017-03-08
US9572797B2 (en) 2017-02-21
US20160143887A1 (en) 2016-05-26
US20110184036A1 (en) 2011-07-28
US10010533B2 (en) 2018-07-03
US11872214B2 (en) 2024-01-16
ES2609106T5 (es) 2020-11-10
RS62327B1 (sr) 2021-10-29
US20230115693A1 (en) 2023-04-13
PT3158991T (pt) 2021-06-23
HUE031208T2 (hu) 2017-07-28
DK2528602T3 (da) 2017-01-23
SMT202100348T1 (it) 2021-07-12
US8609707B2 (en) 2013-12-17
EP2528602B2 (en) 2020-02-12
US20180000789A1 (en) 2018-01-04
US20210393594A1 (en) 2021-12-23
US12138248B2 (en) 2024-11-12
PL2528602T5 (pl) 2020-09-07
DK3158991T3 (da) 2021-06-14
JP6133943B2 (ja) 2017-05-24
SI2528602T2 (sl) 2020-10-30
JP2016020365A (ja) 2016-02-04
RS55491B2 (sr) 2020-11-30
EP3895694A1 (en) 2021-10-20
PT2528602T (pt) 2017-01-12
PL2528602T3 (pl) 2017-03-31
CY1124262T1 (el) 2022-07-22
JP5795600B2 (ja) 2015-10-14
RS55491B1 (sr) 2017-04-28
US20190350904A1 (en) 2019-11-21
US20240075013A1 (en) 2024-03-07
CY1118769T1 (el) 2017-07-12
US20180296536A1 (en) 2018-10-18
US20240293372A1 (en) 2024-09-05
US20230115164A1 (en) 2023-04-13
ES2875374T3 (es) 2021-11-10
US20140024691A1 (en) 2014-01-23
HRP20210915T1 (hr) 2021-10-01
US12343333B2 (en) 2025-07-01
US20250186402A1 (en) 2025-06-12
US20250177356A1 (en) 2025-06-05
EP3158991B1 (en) 2021-03-17
PL3158991T3 (pl) 2021-09-27
US20250295637A1 (en) 2025-09-25
SI3158991T1 (sl) 2021-10-29
HUE054836T2 (hu) 2021-10-28
ES2609106T3 (es) 2017-04-18
LT2528602T (lt) 2017-02-27
HRP20161771T1 (hr) 2017-02-24
JP2013518130A (ja) 2013-05-20
CA2787568A1 (en) 2011-08-04

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