DK2580598T3 - Massespektrometrisk måling af ss-laktamaseresisstens - Google Patents

Massespektrometrisk måling af ss-laktamaseresisstens

Info

Publication number
DK2580598T3
DK2580598T3 DK11728209.5T DK11728209T DK2580598T3 DK 2580598 T3 DK2580598 T3 DK 2580598T3 DK 11728209 T DK11728209 T DK 11728209T DK 2580598 T3 DK2580598 T3 DK 2580598T3
Authority
DK
Denmark
Prior art keywords
mass spectrometric
spectrometric measurement
lactamase synthesis
lactamase
synthesis
Prior art date
Application number
DK11728209.5T
Other languages
English (en)
Inventor
Markus Kostrzewa
Karsten Michelmann
Katrin Sparbier
Original Assignee
Bruker Daltonik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bruker Daltonik Gmbh filed Critical Bruker Daltonik Gmbh
Application granted granted Critical
Publication of DK2580598T3 publication Critical patent/DK2580598T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/26—Infectious diseases, e.g. generalised sepsis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/44—Multiple drug resistance

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
DK11728209.5T 2010-06-11 2011-06-10 Massespektrometrisk måling af ss-laktamaseresisstens DK2580598T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102010023452A DE102010023452B4 (de) 2010-06-11 2010-06-11 Massenspektrometrische Messung von β-Lactamase-Resistenzen
PCT/EP2011/059670 WO2011154517A1 (en) 2010-06-11 2011-06-10 MASS SPECTROMETRIC MEASUREMENT OF β-LACTAMASE RESISTANCES

Publications (1)

Publication Number Publication Date
DK2580598T3 true DK2580598T3 (da) 2014-11-17

Family

ID=44387449

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11728209.5T DK2580598T3 (da) 2010-06-11 2011-06-10 Massespektrometrisk måling af ss-laktamaseresisstens

Country Status (11)

Country Link
US (1) US12435352B2 (da)
EP (2) EP2806032B1 (da)
JP (2) JP6055762B2 (da)
CN (1) CN103003699B (da)
AU (1) AU2011263694B2 (da)
BR (1) BR112012031558B8 (da)
CA (1) CA2791627C (da)
DE (1) DE102010023452B4 (da)
DK (1) DK2580598T3 (da)
ES (2) ES2544315T3 (da)
WO (1) WO2011154517A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0762655B2 (ja) 1986-12-20 1995-07-05 新光電気工業株式会社 検査装置
DE102010023452B4 (de) 2010-06-11 2012-11-08 Bruker Daltonik Gmbh Massenspektrometrische Messung von β-Lactamase-Resistenzen
CN107881210A (zh) 2010-08-19 2018-04-06 伊拉斯谟大学鹿特丹医药中心 表征微生物中抗生素抗性的方法和设备
WO2013053953A1 (en) * 2011-10-14 2013-04-18 Université de Liège Method for measuring beta-lactam antibiotics
WO2013182647A2 (en) 2012-06-06 2013-12-12 Idmic Sa Method for detecting susceptibility of microorganisms to chemical agents
EP2778232A1 (en) * 2013-03-12 2014-09-17 Universität Heidelberg Method for the detection of multiresistant gram-negative bacteria
US10041953B2 (en) 2013-04-04 2018-08-07 Erasmus University Medical Center Rotterdam Mass spectrometric determination of drug resistance
ES2545873T3 (es) 2013-05-23 2015-09-16 Bruker Daltonik Gmbh Determinación de resistencia con espectrometría de masas mediante la medición de la proliferación microbiana
CZ2013473A3 (cs) 2013-06-20 2014-11-26 Univerzita Karlova v Praze, Lékařská fakulta v Plzni Způsob detekce beta-laktamáz gramnegativních bakterií hmotnostní spektrometrií
CN103645273B (zh) * 2013-12-12 2015-12-30 宁波诺威医疗器械有限公司 β-内酰胺类抗生素耐药性的检测方法、系统及其应用
DE102014000646B4 (de) 2014-01-17 2023-05-11 Bruker Daltonics GmbH & Co. KG Massenspektrometrische Resistenzbestimmung durch Metabolismus-Messung
FR3024465B1 (fr) * 2014-07-30 2018-03-23 Biomerieux Caracterisation de micro-organismes par maldi-tof
EP3081652B1 (de) 2015-04-13 2017-06-28 Bruker Daltonik GmbH Massenspektrometrischer schnelltest von resistenzen
CN105403640A (zh) * 2015-12-29 2016-03-16 杭州迪安生物技术有限公司 一种细菌氨苄西林耐药的检测方法及检测试剂盒
WO2018183675A1 (en) * 2017-03-29 2018-10-04 Specific Technologies, LLC Susceptibility and resistance of microorganisms
BR112022009244A2 (pt) 2019-11-15 2022-08-02 Hoffmann La Roche Complexo, composição, kit, uso de um complexo, substância antibiótica derivatizada, método para produzir uma substância antibiótica estabilizada e usos de um reagente de derivatização nucleofílica e de um antibiótico derivatizado
FR3103197B1 (fr) 2019-11-15 2024-08-30 Biomerieux Sa Determination par spectrometrie de masse de la sensibilite ou de la resistance de bacteries a un antibiotique
FR3119459A1 (fr) 2021-02-04 2022-08-05 bioMérieux Plaque pour une analyse par spectrometrie de masse utilisant une technique d’ionisation maldi
DE102021130356B3 (de) 2021-11-19 2023-04-20 Bruker Daltonics GmbH & Co. KG Referenzdatensatz-basiertes, spektrometrisches Charakterisieren von Zellsubstraten unter Verwendung von Teilbibliotheken
CN115561355B (zh) * 2022-09-26 2024-04-30 重庆迪纳利医药科技有限责任公司 羧肽酶g2的中和抗体检测方法以及基于lc-ms/ms的检测系统
JP2026013695A (ja) * 2024-07-17 2026-01-29 株式会社島津製作所 微生物の薬剤耐性評価方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641623A (en) * 1995-01-04 1997-06-24 Martin; Mark T. Electrochemiluminescence assay
EP0991944B1 (en) * 1997-06-25 2004-08-25 N.V. Innogenetics S.A. Methods for covalent immobilisation of biomolecules to a carrier by means of a his-tag
US7291480B2 (en) * 2002-03-13 2007-11-06 Black Jennifer A Device and method for detecting antibiotic-inactivating enzymes
NZ538235A (en) 2005-02-15 2008-07-31 Syft Technologies Ltd Evaluation of bacterial growth and antibiotic sensitivity in blood cultures using selected ion flow tube mass spectrometry
DE102006021493B4 (de) 2006-05-09 2010-04-01 Bruker Daltonik Gmbh Massenspektrometrische Messung mikrobieller Resistenzen
US9090885B2 (en) * 2007-07-26 2015-07-28 The University Of Chicago Co-incubating confined microbial communities
EP2370812A2 (en) 2008-12-08 2011-10-05 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Methods and kits for direct detection and susceptibility profiling of beta-lactam resistant bacteria
CN101603051A (zh) * 2009-05-20 2009-12-16 湖北汇特生物医药技术有限公司 利用浮萍lemna minor生产用于治疗感染的抗菌肽
DE102009032649B4 (de) 2009-07-10 2017-12-21 Bruker Daltonik Gmbh Massenspektrometrische Identifizierung von Mikroben nach Unterarten
DE102009033368B4 (de) 2009-07-16 2023-01-26 Bruker Daltonics GmbH & Co. KG Massenspektrometrische Sepsisdiagnose
DE102010023452B4 (de) 2010-06-11 2012-11-08 Bruker Daltonik Gmbh Massenspektrometrische Messung von β-Lactamase-Resistenzen
CN102033102A (zh) * 2010-10-13 2011-04-27 中国科学院上海有机化学研究所 高通量基质辅助激光解析-质谱法筛查奶类制品中β-内酰胺酶类解抗剂

Also Published As

Publication number Publication date
BR112012031558A2 (pt) 2016-10-25
DE102010023452B4 (de) 2012-11-08
AU2011263694B2 (en) 2014-08-28
BR112012031558B1 (pt) 2020-12-08
DE102010023452A1 (de) 2011-12-15
JP6286406B2 (ja) 2018-02-28
US20130095511A1 (en) 2013-04-18
EP2806032A1 (en) 2014-11-26
US12435352B2 (en) 2025-10-07
EP2806032B1 (en) 2015-07-29
CN103003699B (zh) 2015-04-29
JP6055762B2 (ja) 2016-12-27
JP2013529458A (ja) 2013-07-22
JP2016039814A (ja) 2016-03-24
CN103003699A (zh) 2013-03-27
ES2515466T3 (es) 2014-10-29
CA2791627A1 (en) 2011-12-15
WO2011154517A1 (en) 2011-12-15
EP2580598A1 (en) 2013-04-17
BR112012031558B8 (pt) 2023-03-21
EP2580598B1 (en) 2014-08-06
CA2791627C (en) 2018-09-11
ES2544315T3 (es) 2015-08-28

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