DK2616064T3 - Ketorolacformuleringer klar til anvendelse - Google Patents

Ketorolacformuleringer klar til anvendelse Download PDF

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Publication number
DK2616064T3
DK2616064T3 DK11835216T DK11835216T DK2616064T3 DK 2616064 T3 DK2616064 T3 DK 2616064T3 DK 11835216 T DK11835216 T DK 11835216T DK 11835216 T DK11835216 T DK 11835216T DK 2616064 T3 DK2616064 T3 DK 2616064T3
Authority
DK
Denmark
Prior art keywords
formulations ready
ketorolac formulations
ketorolac
ready
formulations
Prior art date
Application number
DK11835216T
Other languages
English (en)
Inventor
Joseph Pergolizzi
Chad James Pickens
Douglas Giles Johnson
Alexander Mironov
Original Assignee
Rtu Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rtu Pharmaceuticals Llc filed Critical Rtu Pharmaceuticals Llc
Application granted granted Critical
Publication of DK2616064T3 publication Critical patent/DK2616064T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK11835216T 2010-10-21 2011-10-21 Ketorolacformuleringer klar til anvendelse DK2616064T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40538410P 2010-10-21 2010-10-21
US201161481602P 2011-05-02 2011-05-02
PCT/US2011/057284 WO2012054831A2 (en) 2010-10-21 2011-10-21 Ready to use ketorolac formulations

Publications (1)

Publication Number Publication Date
DK2616064T3 true DK2616064T3 (da) 2019-11-11

Family

ID=45973506

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11835216T DK2616064T3 (da) 2010-10-21 2011-10-21 Ketorolacformuleringer klar til anvendelse

Country Status (19)

Country Link
US (5) US9421191B2 (da)
EP (3) EP4190327A1 (da)
JP (1) JP6013346B2 (da)
KR (4) KR20140012029A (da)
CN (2) CN108703948A (da)
CA (1) CA2814805C (da)
CY (1) CY1122516T1 (da)
DK (1) DK2616064T3 (da)
ES (2) ES2753981T3 (da)
HR (1) HRP20191994T1 (da)
HU (1) HUE045889T2 (da)
LT (1) LT2616064T (da)
MX (1) MX346879B (da)
PL (1) PL2616064T3 (da)
PT (1) PT2616064T (da)
RS (1) RS59526B1 (da)
SI (1) SI2616064T1 (da)
SM (1) SMT201900656T1 (da)
WO (1) WO2012054831A2 (da)

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LT2616064T (lt) 2010-10-21 2019-11-25 Rtu Pharmaceuticals Llc Parengtos naudoti ketorolako kompozicijos
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US11559521B2 (en) * 2013-07-22 2023-01-24 William Bradley Worthington Analgesic formulations and methods for reduced postoperative nausea and vomiting and enhanced postoperative pain relief
US11992485B2 (en) 2013-07-22 2024-05-28 Hutchison Health, Llc Analgesic formulations and methods for reduced postoperative nausea and vomiting and enhanced postoperative pain relief
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CN119818450A (zh) * 2020-05-19 2025-04-15 南京海融医药科技股份有限公司 一种左酮咯酸的药物组合物及其制备方法
CN114159384B (zh) * 2021-02-07 2023-04-07 南京锐志生物医药有限公司 一种化学性质稳定的低刺激性酮咯酸氨丁三醇注射液
TWI857310B (zh) * 2021-06-24 2024-10-01 大陸商上海雲晟研新生物科技有限公司 酮咯酸胺丁三醇的液體組合物、其製備方法及應用
CN113384524B (zh) * 2021-07-05 2025-08-12 四川尚锐生物医药有限公司 一种稳定的酮咯酸氨丁三醇注射液的制备方法
CN114191384A (zh) * 2021-12-20 2022-03-18 成都倍特药业股份有限公司 一种即用型酮咯酸氨丁三醇和氢溴酸依他佐辛组合液体制剂
CN114432240A (zh) * 2022-03-04 2022-05-06 郑州市中心医院 一种稳定不刺激的酮咯酸氨丁三醇注射液及其制备方法

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Also Published As

Publication number Publication date
KR20200078541A (ko) 2020-07-01
MX2013004393A (es) 2014-09-12
US9421191B2 (en) 2016-08-23
PT2616064T (pt) 2019-11-06
ES2753981T3 (es) 2020-04-15
SMT201900656T1 (it) 2020-01-14
CA2814805C (en) 2021-11-02
HUE045889T2 (hu) 2020-01-28
WO2012054831A2 (en) 2012-04-26
US20180280351A1 (en) 2018-10-04
US9962371B2 (en) 2018-05-08
EP4190327A1 (en) 2023-06-07
CN103167800A (zh) 2013-06-19
US11116750B2 (en) 2021-09-14
JP2013543843A (ja) 2013-12-09
KR102307601B1 (ko) 2021-09-30
ES2933198T3 (es) 2023-02-02
CA2814805A1 (en) 2012-04-26
KR20190085561A (ko) 2019-07-18
HRP20191994T1 (hr) 2020-02-07
EP3632432A1 (en) 2020-04-08
KR20180119610A (ko) 2018-11-02
WO2012054831A3 (en) 2012-06-07
JP6013346B2 (ja) 2016-10-25
EP2616064B1 (en) 2019-08-07
RS59526B1 (sr) 2019-12-31
CN108703948A (zh) 2018-10-26
EP2616064A4 (en) 2016-07-20
US20190105301A1 (en) 2019-04-11
MX346879B (es) 2017-04-03
KR20140012029A (ko) 2014-01-29
PL2616064T3 (pl) 2020-02-28
SI2616064T1 (sl) 2019-12-31
CY1122516T1 (el) 2021-01-27
US20120101142A1 (en) 2012-04-26
US20170007575A1 (en) 2017-01-12
EP3632432B1 (en) 2022-09-14
EP2616064A2 (en) 2013-07-24
US20220023260A1 (en) 2022-01-27
US10278959B2 (en) 2019-05-07
KR102114568B1 (ko) 2020-05-22
LT2616064T (lt) 2019-11-25

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