DK26394A - Fremgangsmåde til fremstilling af eicosa-5,8,11-triynsyre - Google Patents

Fremgangsmåde til fremstilling af eicosa-5,8,11-triynsyre Download PDF

Info

Publication number: DK26394A
Authority: DK; Denmark
Prior art keywords: acid; reacted; triynic; eicosa; preparation
Prior art date: 1985-07-05

Application number

DK026394A

Other languages

English (en)

Other versions

DK171612B1 (da

Inventor

Braham Shroot

Christopher Hensby

Jean Maignan

Gerard Lang

Serge Restle

Michel Colin

Original Assignee

Cird Galderma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-07-05

Filing date

1994-03-07

Publication date

1994-03-07

1994-03-07 Application filed by Cird Galderma filed Critical Cird Galderma

1994-03-07 Publication of DK26394A publication Critical patent/DK26394A/da

1997-02-24 Application granted granted Critical

1997-02-24 Publication of DK171612B1 publication Critical patent/DK171612B1/da

Links

239000002253 acid Substances 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
150000001408 amides Chemical class 0.000 abstract 3
150000002148 esters Chemical class 0.000 abstract 3
NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical group CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 2
OWYNLPMPYBYKJP-UHFFFAOYSA-N 5,8,11-icosatriynoic acid Chemical compound CCCCCCCCC#CCC#CCC#CCCCC(O)=O OWYNLPMPYBYKJP-UHFFFAOYSA-N 0.000 abstract 2
UNSRRHDPHVZAHH-UHFFFAOYSA-N 6beta,11alpha-Dihydroxy-3alpha,5alpha-cyclopregnan-20-on Natural products CCCCCCCCC=CCC=CCC=CCCCC(O)=O UNSRRHDPHVZAHH-UHFFFAOYSA-N 0.000 abstract 2
150000001412 amines Chemical class 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
PFKFTWBEEFSNDU-UHFFFAOYSA-N carbonyldiimidazole Chemical compound C1=CN=CN1C(=O)N1C=CN=C1 PFKFTWBEEFSNDU-UHFFFAOYSA-N 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
ILLHQJIJCRNRCJ-UHFFFAOYSA-N dec-1-yne Chemical compound CCCCCCCCC#C ILLHQJIJCRNRCJ-UHFFFAOYSA-N 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
VPFMEXRVUOPYRG-UHFFFAOYSA-N hex-5-ynoic acid Chemical compound OC(=O)CCCC#C VPFMEXRVUOPYRG-UHFFFAOYSA-N 0.000 abstract 1
XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
150000003512 tertiary amines Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/18—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon triple bonds as unsaturation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/64—Acyl halides
- C07C57/68—Acyl halides with only carbon-to-carbon triple bonds as unsaturation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/20—Free hydroxyl or mercaptan

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Dermatology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Birds (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Emergency Medicine (AREA)
Immunology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cosmetics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK026394A 1985-07-05 1994-03-07 Fremgangsmåde til fremstilling af eicosa-5,8,11-triynsyre DK171612B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8510363		1985-07-05
FR8510363A FR2584400B1 (fr)	1985-07-05	1985-07-05	Esters et amides de l'acide eicosatriynoique et leur application en pharmacie et en cosmetique

Publications (2)

Publication Number	Publication Date
DK26394A true DK26394A (da)	1994-03-07
DK171612B1 DK171612B1 (da)	1997-02-24

Family

ID=9321030

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK320286A DK171613B1 (da)	1985-07-05	1986-07-04	Eicosatriynsyre-5,8,11-forbindelser og fremgangsmåde til fremstilling deraf samt lægemidler og kosmetiske midler indeholdende dem og deres anvendelse til fremstilling af et lægemiddel
DK026394A DK171612B1 (da)	1985-07-05	1994-03-07	Fremgangsmåde til fremstilling af eicosa-5,8,11-triynsyre

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK320286A DK171613B1 (da)	1985-07-05	1986-07-04	Eicosatriynsyre-5,8,11-forbindelser og fremgangsmåde til fremstilling deraf samt lægemidler og kosmetiske midler indeholdende dem og deres anvendelse til fremstilling af et lægemiddel

Country Status (18)

Country	Link
US (3)	US4877789A (da)
EP (1)	EP0209770B1 (da)
JP (2)	JP2603620B2 (da)
AT (1)	ATE46318T1 (da)
AU (1)	AU600233B2 (da)
CA (1)	CA1267141A (da)
DE (1)	DE3665577D1 (da)
DK (2)	DK171613B1 (da)
ES (1)	ES2000456A6 (da)
FI (1)	FI91394C (da)
FR (1)	FR2584400B1 (da)
GR (1)	GR861746B (da)
IE (1)	IE59112B1 (da)
IL (1)	IL79337A0 (da)
NO (1)	NO171905C (da)
NZ (1)	NZ216751A (da)
PT (1)	PT82912B (da)
ZA (1)	ZA864994B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4749563A (en) *	1986-12-08	1988-06-07	Charles Of The Ritz Group Ltd.	Moisture-resistant skin treatment compositions
FR2609026B1 (fr) *	1986-12-31	1989-03-31	Cird	Amides de l'acide eicosatetraynoique et leur application en pharmacie et en cosmetique
US4908162A (en) *	1988-11-22	1990-03-13	David Rubin	Method of making triple bonded unsaturated fatty acids
EP0396251A3 (en) *	1989-03-31	1992-07-08	National University Of Singapore	Use of fatty acids for the treatment of diseases associated with cytokines
CA2015946A1 (en) *	1989-06-27	1990-12-27	Lawrence P. Klemann	Diol lipid analogues as edible fat replacements
AU670094B2 (en) *	1992-04-23	1996-07-04	Berlex Laboratories, Inc.	Bioadhesive solid mineral oil emulsion
IL103932A (en) *	1992-11-30	1997-02-18	Yissum Res & Dev	Fatty acid and pharmaceutical compositions containing them
JPH0741421A (ja) *	1993-05-28	1995-02-10	Suntory Ltd	ロイコトリエンｂ４（ｌｔｂ４）による医学的症状の予防及び改善剤
US6414017B2 (en)	1993-05-28	2002-07-02	The Gillette Company	Inhibition of hair growth
US6239170B1 (en)	1993-05-28	2001-05-29	Gurpreet S. Ahluwalia	Inhibition of hair growth
US6248751B1 (en)	1993-05-28	2001-06-19	Gurpreet S. Ahluwalia	Inhibition of hair growth
US20040122105A1 (en) *	2002-09-20	2004-06-24	Griscom Bettle	Transdermal compositions
US7368249B2 (en) *	2003-07-24	2008-05-06	The Curators Of The University Of Missouri	Methods and compositions for evaluation and modulation of fertility
JP2019189567A (ja) *	2018-04-26	2019-10-31	東ソー株式会社	アルカノールアミン、モリブデン組成物、及び潤滑油組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4190669A (en) *	1976-03-08	1980-02-26	The Regents Of The University Of Michigan	Method for treating psoriasis
US4497827A (en) *	1982-08-30	1985-02-05	Syntex (U.S.A.) Inc.	Arachidonic acid analogues as anti-inflammatory and anti-allergic agents
FR2609026B1 (fr) *	1986-12-31	1989-03-31	Cird	Amides de l'acide eicosatetraynoique et leur application en pharmacie et en cosmetique

1985
- 1985-07-05 NZ NZ216751A patent/NZ216751A/xx unknown
- 1985-07-05 FR FR8510363A patent/FR2584400B1/fr not_active Expired
1986
- 1986-06-25 FI FI862698A patent/FI91394C/fi not_active IP Right Cessation
- 1986-07-03 PT PT82912A patent/PT82912B/pt not_active IP Right Cessation
- 1986-07-03 US US06/881,776 patent/US4877789A/en not_active Expired - Lifetime
- 1986-07-03 NO NO862692A patent/NO171905C/no unknown
- 1986-07-04 DK DK320286A patent/DK171613B1/da not_active IP Right Cessation
- 1986-07-04 IL IL79337A patent/IL79337A0/xx unknown
- 1986-07-04 ES ES8600133A patent/ES2000456A6/es not_active Expired
- 1986-07-04 JP JP61157770A patent/JP2603620B2/ja not_active Expired - Lifetime
- 1986-07-04 GR GR861746A patent/GR861746B/el unknown
- 1986-07-04 AT AT86109150T patent/ATE46318T1/de not_active IP Right Cessation
- 1986-07-04 DE DE8686109150T patent/DE3665577D1/de not_active Expired
- 1986-07-04 EP EP86109150A patent/EP0209770B1/fr not_active Expired
- 1986-07-04 ZA ZA864994A patent/ZA864994B/xx unknown
- 1986-07-04 IE IE181086A patent/IE59112B1/en not_active IP Right Cessation
- 1986-07-07 CA CA000513255A patent/CA1267141A/fr not_active Expired - Lifetime
- 1986-07-07 AU AU59786/86A patent/AU600233B2/en not_active Ceased
1989
- 1989-09-22 US US07/411,043 patent/US5066427A/en not_active Expired - Fee Related
1993
- 1993-05-17 US US08/061,268 patent/US5310959A/en not_active Expired - Fee Related
1994
- 1994-03-07 DK DK026394A patent/DK171612B1/da not_active IP Right Cessation
1995
- 1995-10-11 JP JP7263338A patent/JP2634394B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DK320286D0 (da)	1986-07-04
GR861746B (en)	1986-11-04
EP0209770B1 (fr)	1989-09-13
NO862692L (no)	1987-01-06
JP2603620B2 (ja)	1997-04-23
DK171612B1 (da)	1997-02-24
FI91394B (fi)	1994-03-15
JPS62129241A (ja)	1987-06-11
IE861810L (en)	1987-01-05
JP2634394B2 (ja)	1997-07-23
NO862692D0 (no)	1986-07-03
FR2584400A1 (fr)	1987-01-09
JPH08188548A (ja)	1996-07-23
FI862698A0 (fi)	1986-06-25
AU600233B2 (en)	1990-08-09
DK171613B1 (da)	1997-02-24
FR2584400B1 (fr)	1988-02-19
PT82912A (fr)	1986-08-01
NO171905C (no)	1993-05-19
AU5978686A (en)	1987-01-08
NO171905B (no)	1993-02-08
NZ216751A (en)	1990-01-29
US5310959A (en)	1994-05-10
ZA864994B (en)	1988-03-30
EP0209770A1 (fr)	1987-01-28
CA1267141A (fr)	1990-03-27
DK320286A (da)	1987-01-06
PT82912B (pt)	1988-05-27
FI91394C (fi)	1994-06-27
IE59112B1 (en)	1994-01-12
DE3665577D1 (en)	1989-10-19
ES2000456A6 (es)	1988-03-01
US4877789A (en)	1989-10-31
US5066427A (en)	1991-11-19
IL79337A0 (en)	1986-10-31
FI862698A7 (fi)	1987-01-06
ATE46318T1 (de)	1989-09-15

Legal Events

Date	Code	Title	Description
1997-02-24	B1	Patent granted (law 1993)
2004-04-05	PBP	Patent lapsed	Country of ref document: DK

Publication	Publication Date	Title
NZ216751A (en)	1990-01-29	Eicosatriynoic acid esters and amides,pharmaceutical compositions and process for preparing eicosatriynoic acid
IT1051637B (it)	1981-05-20	Procedimento per la preparazione dell ammidi mediante idrolisi biologica
ES2000910A6 (es)	1988-03-16	Procedimiento para preparar piridina-2,3-dicarboxilatos sustituidos y disustituidos
PT81214B (pt)	1988-01-22	Processo de preparacao de derivados de acido 3-amino-2-benzoilacrilico
ATE74606T1 (de)	1992-04-15	Verfahren zur herstellung von (+)-biotin.
ATE12500T1 (de)	1985-04-15	Verfahren zur herstellung von isosorbid-2-nitrat.
GB1481594A (en)	1977-08-03	Quaternary compounds and their use in nickel-brightener-leveler compositions
IT7849725A0 (it)	1978-06-06	Procedimento per produrre ammidi di acido carbossilico n-alchil-sosti tuite
ES412872A1 (es)	1975-12-16	Procedimiento para la obtencion de acido 2,5-dicloro-3-ni- trobenzoico puro.
ES8206542A1 (es)	1982-08-16	Procedimiento para la obtencion de fosfonoformaldehido
ES471783A1 (es)	1979-10-16	Procedimiento de preparacion de n,n-bis-(3-oxazolidinil-2- ona) fosforanos-p-triclorados para su aplicacion a la obten-cion de amidas y esteres
GB2013689A (en)	1979-08-15	Enkephalin analogues
UST979003I4 (en)	1979-02-06	Method for preparing N-(carboxyethyl-p-aminophenol
ES479628A1 (es)	1979-11-01	Un procedimiento para preparar clorhidrato de p-clorofenoxia-acetil-piperonilpiperacina.
KR850001744A (ko)	1985-04-01	4-r'-5-q-1,6-나프티리딘-2(1h)-온류의 제법
JPS5262234A (en)	1977-05-23	Process for preparation of n_3'-hydroxyphenyl-2-methylbenzamide
JPS5351049A (en)	1978-05-10	Method of producing handicraft by attaching plastic beads to sheet base
IT1143740B (it)	1986-10-22	Processo per la preparazione di esteri dell'acido cianacetico
JPS5424803A (en)	1979-02-24	Production of alkylchloride
ES456466A1 (es)	1978-02-01	Procedimiento de preparacion de 1-tec-butilamino-3-(2,5-diclorofenoxi-2-propanol) racemico y opticamente activo,y de sus sales de adicion acidas
GB1295838A (da)	1972-11-08
JPS5576853A (en)	1980-06-10	Preparation of derivative of terephthalic acid amide
DE3676150D1 (de)	1991-01-24	Verfahren zur herstellung von ergolinyl-thioharnstoffen.
FR1232619A (fr)	1960-10-11	Procédé perfectionné d'obtention d'esters de l'acide acrylique
KR790000050B1 (en)	1979-02-28	Process for preparation of 1,4-dihydro-pyridine derivatives