DK2646452T3 - Chlorering af carbohydrater og carbohydratderivater - Google Patents
Chlorering af carbohydrater og carbohydratderivater Download PDFInfo
- Publication number
- DK2646452T3 DK2646452T3 DK12780983.8T DK12780983T DK2646452T3 DK 2646452 T3 DK2646452 T3 DK 2646452T3 DK 12780983 T DK12780983 T DK 12780983T DK 2646452 T3 DK2646452 T3 DK 2646452T3
- Authority
- DK
- Denmark
- Prior art keywords
- carbohydrate
- chloration
- derivatives
- carbohydrate derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161547356P | 2011-10-14 | 2011-10-14 | |
| PCT/US2012/060068 WO2013056128A1 (en) | 2011-10-14 | 2012-10-12 | Chlorination of carbohydrates and carbohydrate derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2646452T3 true DK2646452T3 (da) | 2016-06-20 |
Family
ID=47116447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12780983.8T DK2646452T3 (da) | 2011-10-14 | 2012-10-12 | Chlorering af carbohydrater og carbohydratderivater |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8691797B2 (da) |
| EP (1) | EP2646452B1 (da) |
| CN (1) | CN103328495B (da) |
| AU (1) | AU2012323934B2 (da) |
| CA (1) | CA2823961C (da) |
| CY (1) | CY1117609T1 (da) |
| DK (1) | DK2646452T3 (da) |
| ES (1) | ES2574261T3 (da) |
| HU (1) | HUE027876T2 (da) |
| MX (1) | MX342969B (da) |
| PT (1) | PT2646452E (da) |
| SG (1) | SG2013049648A (da) |
| WO (1) | WO2013056128A1 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012071385A1 (en) | 2010-11-23 | 2012-05-31 | Lexington Pharmaceutical Laboratories, Llc | Low temperature chlorination of carbohydrates |
| DK2646452T3 (da) | 2011-10-14 | 2016-06-20 | Lexington Pharmaceutical Laboratories Llc | Chlorering af carbohydrater og carbohydratderivater |
| GB2539112B (en) * | 2013-12-16 | 2020-11-04 | Tate & Lyle Tech Ltd | Chlorination of sucrose-6-esters |
| WO2016020635A1 (en) | 2014-08-08 | 2016-02-11 | Tate & Lyle Technology Limited | Chlorination of sucrose-6-esters |
| GB2536480B (en) | 2015-03-17 | 2019-09-04 | Tate & Lyle Tech Ltd | DMF Distillation |
| US10494450B2 (en) * | 2015-05-29 | 2019-12-03 | Lakshmi Prasad ALAPARTHI | Processes for preparation of Sugammadex and intermediates thereof |
| CN105131050B (zh) * | 2015-07-22 | 2018-07-31 | 青岛科技大学 | 一种氯化剂的制备方法及其制备三氯蔗糖的方法 |
| GB2551591B (en) * | 2016-06-23 | 2019-08-07 | Tate & Lyle Tech Ltd | Liquid-liquid extraction of DMF |
| CN106589013B (zh) * | 2016-11-11 | 2019-06-04 | 浙江新和成股份有限公司 | 一种在液液两相体系中制备三氯蔗糖-6-乙酸酯的方法 |
| CN109825336A (zh) * | 2019-02-28 | 2019-05-31 | 翁源广业清怡食品科技有限公司 | 一种三氯蔗糖生产过程中废糖液的资源化处理方法 |
| CN112996798A (zh) * | 2020-12-28 | 2021-06-18 | 安徽金禾实业股份有限公司 | 蔗糖-6-羧酸酯的氯代方法 |
| WO2024082175A1 (zh) | 2022-10-19 | 2024-04-25 | 安徽金禾实业股份有限公司 | 一种三氯蔗糖精品的制备方法 |
Family Cites Families (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4435440A (en) | 1976-01-08 | 1984-03-06 | Tate & Lyle Limited | Sweeteners |
| DE3165986D1 (en) | 1980-07-08 | 1984-10-18 | Tate & Lyle Plc | Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs) |
| JPS60258171A (ja) | 1984-06-04 | 1985-12-20 | Showa Denko Kk | エピクロルヒドリンの製造方法 |
| US4762537A (en) | 1985-11-07 | 1988-08-09 | Aluminum Company Of America | Adsorbent for HCl comprising alumina and acid-treated Y zeolite |
| US5254153A (en) | 1988-10-21 | 1993-10-19 | Cyprus Minerals Company | Cyanide recycling process |
| US4980463A (en) * | 1989-07-18 | 1990-12-25 | Noramco, Inc. | Sucrose-6-ester chlorination |
| US5136031A (en) * | 1990-07-09 | 1992-08-04 | Tate & Lyle Public Limited Company | Chlorination of sugars |
| US5498709A (en) | 1994-10-17 | 1996-03-12 | Mcneil-Ppc, Inc. | Production of sucralose without intermediate isolation of crystalline sucralose-6-ester |
| US6206950B1 (en) | 1998-10-29 | 2001-03-27 | Cargill, Incorporated | Process for recovery of aluminum using high purity salt aluminum flux |
| US6368568B1 (en) | 2000-02-18 | 2002-04-09 | Stephen M Lord | Method for improving the efficiency of a silicon purification process |
| KR100666652B1 (ko) | 2000-02-25 | 2007-01-09 | 한화석유화학 주식회사 | 식물 원료로부터 초임계 유체를 이용하여 탁솔을 제조하는방법 |
| US6860985B2 (en) | 2001-12-12 | 2005-03-01 | Exxonmobil Research And Engineering Company | Process for increasing yield in coking processes |
| US7049435B2 (en) * | 2002-03-08 | 2006-05-23 | Tate & Lyle Public Limited Company | Extractive methods for purifying sucralose |
| US6831181B2 (en) | 2002-04-17 | 2004-12-14 | E. I. Dupont De Nemours And Co. | High yield byproduct recycle process for anhydro sugar alcohols |
| TWI314153B (en) | 2002-07-12 | 2009-09-01 | Mitsui Chemicals Inc | Process for production of oxyalkylene derivative |
| US20040030124A1 (en) | 2002-08-06 | 2004-02-12 | Catani Steven J. | Process for recovering chlorosucrose compounds |
| JP2004143047A (ja) | 2002-10-22 | 2004-05-20 | Daicel Chem Ind Ltd | ε−カプロラクトンの製造方法 |
| US7425258B2 (en) | 2003-02-28 | 2008-09-16 | Exxonmobil Research And Engineering Company | C6 recycle for propylene generation in a fluid catalytic cracking unit |
| CA2537804A1 (en) | 2003-09-05 | 2005-03-17 | Teva Pharmaceutical Industries Ltd | A recycling process for preparing sertraline |
| US7258885B2 (en) | 2004-03-01 | 2007-08-21 | Tasty-Trim, Inc. | Flavored artificial sweetener |
| AU2004317336A1 (en) | 2004-03-19 | 2005-09-29 | V.B. Medicare Private Limited | An improved process for producing chlorinated sucrose |
| WO2006061855A2 (en) | 2004-12-10 | 2006-06-15 | Pharmed Medicare Private Limited | Salts assisted selective extraction of 6-acetyl-4.1', 6' trichlorogalactosucrose and 4, 1 ', 6' trichlorogalactosucrose from aqueous reaction mixture |
| CN101166748A (zh) | 2005-02-22 | 2008-04-23 | 法马德医疗保险私人有限公司 | 在生产氯化蔗糖、其前体和衍生物过程的不同步骤中的分子分离方法 |
| US20090105470A1 (en) | 2005-02-22 | 2009-04-23 | Pharmed Medicare Private Limited , A Corporation | Tin Mediated Regioselective Synthesis of Sucrose-6-Esters |
| CA2606487A1 (en) | 2005-05-04 | 2007-02-15 | Pharmed Medicare Pvt. Ltd. | Generation of phosphorus oxychloride as by-product from phosphorus pentachloride and dmf and its use for chlorination reaction by converting into vilsmeier-haack reagent |
| CA2620875A1 (en) | 2005-08-30 | 2007-05-10 | Pharmed Medicare Pvt. Ltd. | A process for purification of trichlorogalactosucrose based on direct extraction in organic solvent from reaction mixture followed by evaporative removal of solvent |
| CN101273050A (zh) * | 2005-09-22 | 2008-09-24 | 法马德医疗保险私人有限公司 | 缚酸剂在蔗糖-6-乙酸酯的氯化过程中去除反应物料的质子（酸性）中的应用 |
| CN101268091A (zh) | 2005-09-22 | 2008-09-17 | 法马德医疗保险私人有限公司 | 从无水氯化反应物料制备6-o-酰基氯化蔗糖的新型方法 |
| US20080300391A1 (en) | 2005-10-20 | 2008-12-04 | Rakesh Ratnam | Acid Mediated Deacylation of 6-0-Trichlorogalactosurcrose to Trich-Lorogalactosucrose |
| US20070100139A1 (en) | 2005-10-31 | 2007-05-03 | Healthy Brands, Llc | Methods for chlorinating sucrose-6-ester |
| US20100184969A1 (en) | 2005-11-08 | 2010-07-22 | Mangesh Rajadhyaksha | Process to Prepare Sucralose |
| CN101341165A (zh) | 2005-12-09 | 2009-01-07 | V.B.医疗保险私人有限公司 | 作为制造卤化蔗糖的中间体的蔗糖-6-酯的酶促生产 |
| US7741477B2 (en) * | 2006-01-10 | 2010-06-22 | Alembic Limited | Process for purification of sucralose |
| EA200801745A1 (ru) | 2006-02-28 | 2009-02-27 | В.Б. Медикэр Пвт. Лтд. | Новый хлорирующий реагент и новый способ для хлорирования сахаров с использованием тионил хлорида |
| CN1814609B (zh) | 2006-03-06 | 2010-11-10 | 盐城捷康三氯蔗糖制造有限公司 | 一种提高三氯蔗糖合成收率的方法 |
| US20090208747A1 (en) | 2006-03-22 | 2009-08-20 | V.B. Medicare Pvt. Ltd | Novel Crystalline Methods and Novel Crystalline and Amorphous forms of Halogenated Sugars |
| CN100418976C (zh) | 2006-04-03 | 2008-09-17 | 广州科宏食品添加物有限公司 | 一种三氯蔗糖的制备方法 |
| GB2452870A (en) | 2006-04-27 | 2009-03-18 | Vb Medicare Pvt Ltd | Continuous neutralizer mixer reactor and a continuous process for quenching chlorination reaction mixture in production of chlorinated sucrose |
| EP2029522A2 (en) | 2006-05-23 | 2009-03-04 | V.B. Medicare Pvt. Ltd. | Recovery of dimethylformamide and other solvents from process streams of manufacture of trichlorogalactosucrose |
| CN100420697C (zh) | 2006-08-30 | 2008-09-24 | 河北苏科瑞科技有限公司 | 一种制备蔗糖-6-有机酸酯的方法 |
| US20080103295A1 (en) | 2006-10-25 | 2008-05-01 | David Losan Ho | Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst |
| US8258291B2 (en) | 2006-10-25 | 2012-09-04 | Mamtek International Limited | Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC) |
| DE102006053380A1 (de) * | 2006-11-13 | 2008-05-15 | Wacker Chemie Ag | Verfahren zur Herstellung von chlorierten Carbonylverbindungen in Jet Loop Reaktoren |
| AU2007328222A1 (en) | 2006-12-05 | 2008-06-12 | Tate & Lyle Technology Ltd. | Trityl chloride recovery |
| CN101784677A (zh) | 2007-01-08 | 2010-07-21 | V.B.医疗保险私人有限公司 | 通过化学氧化脱色三氯蔗糖生产中的工艺流 |
| US20080227971A1 (en) | 2007-01-19 | 2008-09-18 | Leinhos Duane A | Deacylation of sucralose-6-acylates |
| KR20080073879A (ko) | 2007-02-07 | 2008-08-12 | 주식회사 일신케미칼 | 수크랄로오스의 제조방법 |
| US20080300401A1 (en) | 2007-06-04 | 2008-12-04 | Polymed Therapeutics, Inc. | Novel chlorination process for preparing sucralose |
| US20080300392A1 (en) | 2007-06-04 | 2008-12-04 | Polymed Therapeutics, Inc. | Novel chlorination process for preparing sucralose |
| CN101177437B (zh) * | 2007-12-07 | 2010-10-27 | 浙江普洛医药科技有限公司 | 一种环保的三氯蔗糖的合成方法 |
| CN101245085B (zh) | 2007-12-19 | 2012-02-01 | 上海同辰生物科技有限公司 | 一种三氯蔗糖的合成及纯化工艺 |
| WO2009117317A1 (en) | 2008-03-20 | 2009-09-24 | Tate & Lyle Technology Ltd | Removal of acids from tertiary amide solvents |
| WO2009124113A1 (en) | 2008-04-03 | 2009-10-08 | Tate & Lyle Technology Ltd. | Extraction of less polar impurities from sucralose containing aqueous feed streams |
| US8212022B2 (en) | 2008-04-03 | 2012-07-03 | Tate & Lyle Technology Limited | Effect of carbohydrate concentration on sucralose extraction efficiency |
| AR071134A1 (es) | 2008-04-03 | 2010-05-26 | Tate & Lyle Technology Ltd | Cristalizacion de sucralosa a partir de chorros que contienen sucralosa |
| US20090299055A1 (en) | 2008-04-03 | 2009-12-03 | Tate & Lyle Technology Limited | Purification of Sucralose Containing Feed Streams for Sucralose Crystallization |
| US20100022765A1 (en) | 2008-07-23 | 2010-01-28 | David Losan Ho | Methods for extracting and purifying sucralose intermediate |
| US7733975B1 (en) | 2008-12-31 | 2010-06-08 | Mediatek Inc. | Method for estimating phase error in MIMO OFDM communications system |
| GB2468936B (en) | 2009-03-27 | 2011-09-07 | Mohamad Rami Radwan Jaber | Chlorination of sucrose-6-esters |
| GB2471348B (en) | 2009-06-22 | 2011-12-14 | Tate & Lyle Technology Ltd | A method for producing sucralose-6-acylate |
| WO2012071385A1 (en) | 2010-11-23 | 2012-05-31 | Lexington Pharmaceutical Laboratories, Llc | Low temperature chlorination of carbohydrates |
| DK2646452T3 (da) | 2011-10-14 | 2016-06-20 | Lexington Pharmaceutical Laboratories Llc | Chlorering af carbohydrater og carbohydratderivater |
-
2012
- 2012-10-12 DK DK12780983.8T patent/DK2646452T3/da active
- 2012-10-12 CN CN201280006143.2A patent/CN103328495B/zh active Active
- 2012-10-12 EP EP12780983.8A patent/EP2646452B1/en active Active
- 2012-10-12 HU HUE12780983A patent/HUE027876T2/en unknown
- 2012-10-12 CA CA2823961A patent/CA2823961C/en active Active
- 2012-10-12 SG SG2013049648A patent/SG2013049648A/en unknown
- 2012-10-12 AU AU2012323934A patent/AU2012323934B2/en active Active
- 2012-10-12 MX MX2013007764A patent/MX342969B/es active IP Right Grant
- 2012-10-12 WO PCT/US2012/060068 patent/WO2013056128A1/en not_active Ceased
- 2012-10-12 ES ES12780983.8T patent/ES2574261T3/es active Active
- 2012-10-12 PT PT127809838T patent/PT2646452E/pt unknown
-
2013
- 2013-03-14 US US13/826,851 patent/US8691797B2/en active Active
-
2014
- 2014-03-05 US US14/198,182 patent/US20140187768A1/en not_active Abandoned
-
2016
- 2016-06-08 CY CY20161100501T patent/CY1117609T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1117609T1 (el) | 2017-04-26 |
| EP2646452A1 (en) | 2013-10-09 |
| HUE027876T2 (en) | 2016-10-28 |
| WO2013056128A1 (en) | 2013-04-18 |
| US20140187768A1 (en) | 2014-07-03 |
| CN103328495B (zh) | 2016-10-05 |
| CA2823961A1 (en) | 2013-04-18 |
| US20130197215A1 (en) | 2013-08-01 |
| AU2012323934A1 (en) | 2013-07-11 |
| ES2574261T3 (es) | 2016-06-16 |
| SG2013049648A (en) | 2014-12-30 |
| CA2823961C (en) | 2020-10-06 |
| EP2646452B1 (en) | 2016-03-09 |
| MX2013007764A (es) | 2014-02-11 |
| MX342969B (es) | 2016-10-20 |
| CN103328495A (zh) | 2013-09-25 |
| US8691797B2 (en) | 2014-04-08 |
| AU2012323934B2 (en) | 2017-06-29 |
| PT2646452E (pt) | 2016-06-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO2019041I1 (no) | Kombinasjon av daunorubicin og cytarabin | |
| DK3415157T3 (da) | N-acyldipeptidderivater og anvendelser deraf | |
| DK2646452T3 (da) | Chlorering af carbohydrater og carbohydratderivater | |
| DK2691443T3 (da) | Konjugerede lipomerer og anvendelser af disse | |
| DK3235812T3 (da) | Deutererede derivater af ivacaftor | |
| DK2794654T3 (da) | Anti-phf-tau-antistoffer og deres anvendelser | |
| CO6990717A2 (es) | Derivados de dihidro-benzo-oxazina y dihidro-pirido-oxazina | |
| EP2686331A4 (en) | REBAUDIOSID B AND DERIVATIVES THEREOF | |
| BR302012003140S1 (pt) | Configuração aplicada em relógio | |
| EP2663266C0 (en) | ENDOPROSTHESIS | |
| BR112014009050A2 (pt) | pirrolbenzodiazepinas e conjugados destas | |
| DK2739293T3 (da) | Fremgangsmåder og sammensætninger til frembringelse af vaccinavirus | |
| DK2970872T3 (da) | Mikroorganismer og fremgangsmåder til fremstilling af sialylerede og N-acetylglucosamin-holdige oligosaccharider | |
| IL225514A0 (en) | Ornament | |
| EP2723766A4 (en) | COAGONISTS OF GLUCAGON / GLP-1 RECEPTOR | |
| EP2723367A4 (en) | Glucagon/glp-1 receptor co-agonists | |
| DK2683731T3 (da) | C4-monomethyl-triterpenoidderivater og fremgangsmåder til anvendelse deraf | |
| UY4115Q (es) | Reloj | |
| BR112013024167A2 (pt) | espaçador intercorporal expansível | |
| BR112013019509A2 (pt) | derivados heterocíclicos | |
| HRP20170196T1 (hr) | Derivati dušikovih iperita | |
| PL2678035T3 (pl) | Pochodne fenalen-1-onu, sposób ich wytwarzania i zastosowanie | |
| DK2794850T3 (da) | Bioteknologisk produktion af alkoholer og derivater deraf | |
| DK2723347T3 (da) | Forebyggelse og behandling af inflammationstilstande | |
| EP3659468C0 (en) | FURNITURE ELEMENT |