DK2734636T3 - Mikro-rna-biomarkører til identificering af risikoen for og/eller til diagnosticering af en lungetumor - Google Patents

Mikro-rna-biomarkører til identificering af risikoen for og/eller til diagnosticering af en lungetumor Download PDF

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Publication number
DK2734636T3
DK2734636T3 DK12720568.0T DK12720568T DK2734636T3 DK 2734636 T3 DK2734636 T3 DK 2734636T3 DK 12720568 T DK12720568 T DK 12720568T DK 2734636 T3 DK2734636 T3 DK 2734636T3
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Denmark
Prior art keywords
diagnostication
micro
identifying
risk
lung tumor
Prior art date
Application number
DK12720568.0T
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English (en)
Inventor
Gabriella Sozzi
Ugo Pastorino
Mattia Boeri
Original Assignee
Gabriella Sozzi
Mattia Boeri
Ugo Pastorino
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Filing date
Publication date
Priority claimed from ITMI2011A000172A external-priority patent/IT1406672B1/it
Priority claimed from ITMI2011A000173A external-priority patent/IT1403685B1/it
Priority claimed from ITMI2011A000174A external-priority patent/IT1406866B1/it
Application filed by Gabriella Sozzi, Mattia Boeri, Ugo Pastorino filed Critical Gabriella Sozzi
Application granted granted Critical
Publication of DK2734636T3 publication Critical patent/DK2734636T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK12720568.0T 2011-02-07 2012-02-07 Mikro-rna-biomarkører til identificering af risikoen for og/eller til diagnosticering af en lungetumor DK2734636T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
ITMI2011A000172A IT1406672B1 (it) 2011-02-07 2011-02-07 Procedimento ed apparecchiatura per identificare individui a rischio di tumore polmonare e/o per diagnosticare un tumore polmonare, nonche' composizione e metodo per ridurre o eliminare il rischio di tumore polmonare.
ITMI2011A000173A IT1403685B1 (it) 2011-02-07 2011-02-07 Procedimento ed apparecchiatura per identificare individui a rischio di tumore polmonare e/o per diagnosticare un tumore polmonare, nonche' composizione e metodo per ridurre o eliminare il rischio di tumore polmonare.
ITMI2011A000174A IT1406866B1 (it) 2011-02-07 2011-02-07 Procedimento ed apparecchiatura per identificare individui a rischio di tumore polmonare e/o per diagnosticare un tumore polmonare, nonché composizione e metodo per ridurre o eliminare il rischio di tumore polmonare
US201161522328P 2011-08-11 2011-08-11
PCT/IB2012/000567 WO2012107841A2 (en) 2011-02-07 2012-02-07 Micro-rna biomarkers and methods of using same

Publications (1)

Publication Number Publication Date
DK2734636T3 true DK2734636T3 (da) 2019-08-26

Family

ID=46062629

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12720568.0T DK2734636T3 (da) 2011-02-07 2012-02-07 Mikro-rna-biomarkører til identificering af risikoen for og/eller til diagnosticering af en lungetumor

Country Status (17)

Country Link
US (4) US20120225925A1 (da)
EP (1) EP2734636B1 (da)
AU (2) AU2012215105B2 (da)
BR (1) BR112014003877A2 (da)
CA (1) CA2844596A1 (da)
CY (1) CY1121916T1 (da)
DK (1) DK2734636T3 (da)
ES (1) ES2742840T3 (da)
HK (1) HK1197274A1 (da)
HR (1) HRP20191481T1 (da)
HU (1) HUE045731T2 (da)
IL (1) IL230896B (da)
PL (1) PL2734636T3 (da)
PT (1) PT2734636T (da)
RS (1) RS59161B1 (da)
SM (1) SMT201900474T1 (da)
WO (1) WO2012107841A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE045731T2 (hu) 2011-02-07 2020-01-28 Gabriella Sozzi Mikro-RNS biomarkerek tüdõtumor diagnosztizálásához és/vagy kockázatának azonosításához
EP2733219B1 (en) * 2012-11-16 2017-09-20 Siemens Aktiengesellschaft Diagnostic miRNA markers for Alzheimer
CN104903468B (zh) 2012-11-16 2019-04-23 萨尔大学 用于帕金森氏病的新诊断MiRNA标志物
CN122038564A (zh) * 2014-01-05 2026-05-15 G·索兹 使用mirna比率确定肺癌
WO2015117205A1 (en) * 2014-02-06 2015-08-13 Immunexpress Pty Ltd Biomarker signature method, and apparatus and kits therefor
US20160068913A1 (en) * 2014-09-09 2016-03-10 Istituto Europeo Di Oncologia S.R.L. Methods for Lung Cancer Detection
US10358679B2 (en) * 2014-09-26 2019-07-23 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. MicroRNA biomarkers for posttraumatic stress disorder and methods of use thereof
EP3206697A2 (en) * 2014-10-17 2017-08-23 Biomirna Holdings Ltd. Lung cancer diagnostics and therapeutics with mir-660
TWI571514B (zh) * 2015-01-09 2017-02-21 長庚大學 評估罹患大腸直腸癌風險的方法
TWI626314B (zh) * 2015-01-09 2018-06-11 長庚大學 評估罹患大腸直腸癌風險的方法
WO2018187624A1 (en) * 2017-04-06 2018-10-11 The United States Government As Represented By The Department Of Veterans Affairs Methods of detecting lung cancer

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2857878A1 (en) * 2004-11-12 2006-12-28 Asuragen, Inc. Methods and compositions involving mirna and mirna inhibitor molecules
EP2502630B1 (en) * 2006-01-05 2015-03-11 The Ohio State University Research Foundation MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer
EP2484782B1 (en) * 2006-01-05 2015-11-18 The Ohio State University Research Foundation MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers
US8207325B2 (en) * 2006-04-03 2012-06-26 Univ. of Copenhagen MicroRNA biomarkers for human breast and lung cancer
EP2198050A1 (en) * 2007-09-14 2010-06-23 Asuragen, INC. Micrornas differentially expressed in cervical cancer and uses thereof
WO2009052386A1 (en) * 2007-10-18 2009-04-23 Asuragen, Inc. Micrornas differentially expressed in lung diseases and uses thereof
CN101918594A (zh) * 2007-11-30 2010-12-15 俄亥俄州立大学研究基金会 肺癌中外周血中的微rna表达特征谱和靶向
WO2009147525A1 (en) * 2008-06-04 2009-12-10 Karolinska Institutet Innovations Ab Skin cancer associated micrornas
AU2010218147A1 (en) * 2009-02-26 2011-10-20 The Government Of The United States Of America As Represented By The Secretary Of The Dept. Of Health & Human Services MicroRNAs in never-smokers and related materials and methods
EP2341145A1 (en) * 2009-12-30 2011-07-06 febit holding GmbH miRNA fingerprint in the diagnosis of diseases
EP2354246A1 (en) * 2010-02-05 2011-08-10 febit holding GmbH miRNA in the diagnosis of ovarian cancer
CN101804208A (zh) * 2010-02-26 2010-08-18 南京医科大学 miR-451在制备治疗非小细胞肺癌药物的应用
HUE045731T2 (hu) 2011-02-07 2020-01-28 Gabriella Sozzi Mikro-RNS biomarkerek tüdõtumor diagnosztizálásához és/vagy kockázatának azonosításához

Also Published As

Publication number Publication date
WO2012107841A2 (en) 2012-08-16
IL230896A0 (en) 2014-03-31
US20190062843A1 (en) 2019-02-28
US20210130905A1 (en) 2021-05-06
US9926603B2 (en) 2018-03-27
BR112014003877A2 (pt) 2017-06-13
SMT201900474T1 (it) 2019-09-09
US20150045233A1 (en) 2015-02-12
CY1121916T1 (el) 2020-10-14
AU2017213457B2 (en) 2019-08-29
PL2734636T3 (pl) 2019-10-31
AU2017213457A1 (en) 2017-08-31
ES2742840T3 (es) 2020-02-17
HUE045731T2 (hu) 2020-01-28
US20120225925A1 (en) 2012-09-06
PT2734636T (pt) 2019-09-06
WO2012107841A3 (en) 2013-01-17
EP2734636B1 (en) 2019-05-22
EP2734636A2 (en) 2014-05-28
AU2012215105A1 (en) 2014-06-05
AU2012215105B2 (en) 2017-05-11
HRP20191481T1 (hr) 2019-11-15
CA2844596A1 (en) 2012-08-16
RS59161B1 (sr) 2019-10-31
HK1197274A1 (en) 2015-01-09
IL230896B (en) 2019-10-31

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