DK2819667T3 - Retinalderivater til anvendelse til forbedring af synsfunktionen - Google Patents

Retinalderivater til anvendelse til forbedring af synsfunktionen Download PDF

Info

Publication number: DK2819667T3
Authority: DK; Denmark
Prior art keywords: improve; vision function; retinal derivatives; retinal; derivatives
Prior art date: 2012-03-01

Application number

DK13760943.4T

Other languages

English (en)

Inventor

Suzanne Cadden

Original Assignee

Retinagenix Therapeutics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-03-01

Filing date

2013-03-01

Publication date

2020-03-30

2013-03-01 Application filed by Retinagenix Therapeutics Inc filed Critical Retinagenix Therapeutics Inc

2020-03-30 Application granted granted Critical

2020-03-30 Publication of DK2819667T3 publication Critical patent/DK2819667T3/da

Links

150000003726 retinal derivatives Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Ophthalmology & Optometry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK13760943.4T 2012-03-01 2013-03-01 Retinalderivater til anvendelse til forbedring af synsfunktionen DK2819667T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201261605729P	2012-03-01	2012-03-01
US201261642212P	2012-05-03	2012-05-03
US201261644360P	2012-05-08	2012-05-08
PCT/CA2013/050155 WO2013134867A1 (en)	2012-03-01	2013-03-01	Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency

Publications (1)

Publication Number	Publication Date
DK2819667T3 true DK2819667T3 (da)	2020-03-30

Family

ID=49160185

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK13760943.4T DK2819667T3 (da)	2012-03-01	2013-03-01	Retinalderivater til anvendelse til forbedring af synsfunktionen

Country Status (16)

Country	Link
US (2)	US20160296478A1 (da)
EP (1)	EP2819667B8 (da)
JP (3)	JP6576636B2 (da)
KR (1)	KR102133608B1 (da)
CN (2)	CN109248163A (da)
AU (3)	AU2013232697B2 (da)
BR (1)	BR112014021602A2 (da)
CA (1)	CA2865935C (da)
DK (1)	DK2819667T3 (da)
ES (1)	ES2780357T3 (da)
IL (1)	IL234306B (da)
MX (2)	MX389866B (da)
NZ (1)	NZ629267A (da)
PT (1)	PT2819667T (da)
RU (1)	RU2635536C2 (da)
WO (1)	WO2013134867A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR101851249B1 (ko)	2010-04-19	2018-06-20	노벨리언 테라퓨틱스 인코포레이티드	내인성 레티노이드 결핍과 연관된 시각 장애의 치료 또는 완화를 위한 치료용 조성물, 제형 및 키트
KR102133608B1 (ko)	2012-03-01	2020-07-13	레티나제닉스, 엘엘씨	내인성 레티노이드 결핍증과 관련된 시각 장애에서 시각 기능의 개선을 위한 치료 요법 및 방법
WO2015164419A1 (en) *	2014-04-22	2015-10-29	Acucela Inc.	Pupillometric assessment of retinal pharmacodynamics and responses therefrom
EP3294711B1 (en) *	2015-05-08	2020-01-08	University of Debrecen	Stereoselective synthesis of 9-cis-13,14-dihydroretinoic acid and its ethyl esters
US12029715B2 (en) *	2015-05-08	2024-07-09	University Of Debrecen	Precursor compounds for providing retinoids of the vitamin A5 pathway and uses thereof
AU2017359593B2 (en)	2016-11-17	2022-03-17	Universidade De Vigo	Precursor compounds for providing retinoids of the vitamin A5 pathway and uses thereof
RU186184U1 (ru) *	2018-06-06	2019-01-11	Федеральное государственное бюджетное учреждение "33 Центральный научно-исследовательский испытательный институт" Министерства обороны Российской Федерации	Устройство для оценки углов обзора и поля зрения испытателей в противогазе
CA3178762A1 (en) *	2020-06-09	2021-12-16	Eluminex Biosciences (Suzhou) Limited	Methods of treating visual disorders using daily low dosing of a retinoid compound
WO2024110625A1 (en)	2022-11-24	2024-05-30	Universität Bern	Cralbp based therapeutics for retinal disorders

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3196078A (en)	1962-01-30	1965-07-20	Ortho Pharma Corp	Process for combating retinits pigmentosa
US3517067A (en)	1964-02-11	1970-06-23	Eastman Kodak Co	Syntheses of quaternary phosphonium salts
DE2300107C2 (de)	1973-01-03	1982-03-11	Basf Ag, 6700 Ludwigshafen	Vitamin A-Säureanilid-4-carbonsäureäthylester, Verfahren zu seiner Herstellung und diesen enthaltende Zubereitungen
CH590222A5 (da)	1973-08-21	1977-07-29	Hoffmann La Roche
US4022913A (en)	1973-09-13	1977-05-10	Hoffmann-La Roche Inc.	High potency vitamin A compositions
DE2456959A1 (de)	1974-12-03	1976-06-16	Basf Ag	4-(e)- und 4-(z)-7-methyl-9-(2,6,6trimethyl-1-cyclohexen-1-yl)-nona-2,4,6,8tetraencarbonsaeure, ihre derivate und diese enthaltende zubereitungen
CA1198859A (en)	1982-04-21	1986-01-07	Chester L. O'neal	Disposable toothbrush with cap
US4532133A (en)	1983-05-24	1985-07-30	Basf Wyandotte Corporation	Low temperature stable, emulsifiable vitamin A concentrates
CA1282326C (en)	1984-12-14	1991-04-02	Paul J. Jarosz	Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient
JPS61275266A (ja)	1985-05-28	1986-12-05	Taisho Pharmaceut Co Ltd	レチノイド誘導体
CZ282548B6 (cs)	1992-01-22	1997-08-13	F. Hoffmann-La Roche Ag	Farmaceutický přípravek
US5310764A (en)	1992-05-08	1994-05-10	Steven Baranowitz	Treatment of age related macular degeneration with beta-carotene
JPH06340525A (ja)	1993-06-02	1994-12-13	Lion Corp	安定な低眼刺激性ビタミンａ類可溶化点眼剤
NZ283658A (en)	1994-04-04	1999-09-29	William R Freeman	Compositions and treatment of increased intraocular pressure with phosphonyl-alkyloxy-pyrimidines/purines (nucleosides)
RU2106843C1 (ru)	1994-06-29	1998-03-20	Красноярская государственная медицинская академия	Способ лечения близорукости
JPH08198746A (ja)	1995-01-18	1996-08-06	Lion Corp	可溶化点眼剤
US5837728A (en)	1995-01-27	1998-11-17	Molecular Design International	9-cis retinoic acid esters and amides and uses thereof
US5489611A (en)	1995-02-10	1996-02-06	Warner-Lambert Company	Method for lowering plasma levels of lipoprotein (a)
US5620970A (en)	1995-06-05	1997-04-15	Alcon Laboratories, Inc.	Topical ophthalmic carbonic anhydrase inhibitor formulations
AU6390096A (en)	1995-07-20	1997-02-18	Pharmacia & Upjohn Company	Stable clear solutions of non-steroidal anti-inflammatory drugs for incorporation into gelatin capsules
US5716627A (en)	1996-04-25	1998-02-10	Elizabeth Arden Co., Division Of Conopco, Inc.	Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester
EP0908179A1 (en)	1997-08-23	1999-04-14	Werner Bollag	Treatment of cell-mediated immune diseases
ZA989513B (en)	1997-10-21	1999-04-21	Alcon Lab Inc	Compositions containing histamine H2 agonists and methods of use in treating dry eye
US6391924B1 (en)	1997-12-10	2002-05-21	Hampar Karageozian	Taurine derivatives useable in the treatment of ophthalmic disorders
US6552009B2 (en)	1998-07-16	2003-04-22	Gentrix Llc	Compositions and methods of treating abnormal cell proliferation
US6267985B1 (en)	1999-06-30	2001-07-31	Lipocine Inc.	Clear oil-containing pharmaceutical compositions
US6372463B1 (en)	1999-05-06	2002-04-16	The President & Fellows Of Harvard College	Mutations in nucleic acid molecules encoding 11-CIS retinol dehydrogenase, the mutated proteins, and uses thereof
US6300328B1 (en)	1999-08-06	2001-10-09	Alcon Universal Ltd.	Selective inhibitors of adenosine monophosphate deaminase for the treatment of optic nerve and retinal damage
US20020028849A1 (en)	2000-04-18	2002-03-07	Godkin James D.	Use of retinol in assisted-reproduction protocols
US6696069B2 (en)	2000-06-30	2004-02-24	Unilever Home & Personal Care Usa, Division Of Conopco, Inc.	Skin care cosmetic compositions containing phosphates and/or sulfates of branched alcohols and/or ethoxylates thereof
US20040077604A1 (en)	2001-12-19	2004-04-22	Lenard Lichtenberger	Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity
US7030265B2 (en)	2001-01-11	2006-04-18	Chebigen, Inc.	Retinol derivatives, the method of preparations and the uses thereof
WO2002082904A2 (en)	2001-04-13	2002-10-24	The Trustees Of The University Of Pennsylvania	Method of treating or retarding the development of blindness
ITMI20012366A1 (it)	2001-11-09	2003-05-09	Farmatron Ltd	Sistemi terapeutici stabilizzati a rilascio immediato e/o modificato per la somministrazione orale di principi attivi e/o eccipienti e/o ali
US7875728B2 (en)	2001-11-30	2011-01-25	Valocor Therapeutics, Inc.	Hydrazonopyrazole derivatives and their use as therapeutics
WO2003059336A1 (en)	2002-01-18	2003-07-24	Tatton Technologies, Llc.	Methods for treating eye disorders
US20030215413A1 (en)	2002-03-22	2003-11-20	L'oreal	Compositions containing stabilized retinoid
US20040097587A1 (en)	2002-03-27	2004-05-20	Arbiser Jack L	Compositions and methods of treatment of ulcerating diseases, burns, and related conditions
KR20040095250A (ko)	2002-03-29	2004-11-12	맥심 파마수티컬즈 인크.	안내 손상의 치료 및 예방에 사용하기 위한 활성 산소대사물(ｒｏｍ)의 생성 및 방출 억제제의 용도
JP3854524B2 (ja)	2002-04-01	2006-12-06	ピアス株式会社	油溶性成分安定化組成物及びその組成物を配合した化粧料、並びに油溶性成分の安定化方法
EP1367493A1 (en)	2002-05-30	2003-12-03	STMicroelectronics Limited	Prefetch buffer
EP1527774A1 (en)	2003-11-03	2005-05-04	Basilea Pharmaceutica AG	New formulation for retinoid-containing soft gelatin capsules
US20040242704A1 (en)	2003-03-14	2004-12-02	University Of Washington, Techtransfer - Invention Licensing	Stabilized mutant opsin proteins
EP1510133A1 (en)	2003-09-01	2005-03-02	Belovo S.A., Egg Science & Technology	Balanced oil composition
ES2574004T3 (es)	2003-09-04	2016-06-14	The Uab Research Foundation	Procedimiento y aparato para la detección del deterioro en la adaptación a la oscuridad
US7706863B2 (en)	2004-01-21	2010-04-27	University Of Washington	Methods for assessing a physiological state of a mammalian retina
AU2005215778B2 (en)	2004-02-17	2009-03-12	President And Fellows Of Harvard College	Management of ophthalmologic disorders, including macular degeneration
US7919526B2 (en)	2004-03-04	2011-04-05	Htl High-Tech Lipids Ltd.	Structured triglycerides and emulsions comprising same
US9421175B2 (en)	2004-03-17	2016-08-23	Lars Michael Larsen	Prevention of retinopathy by inhibition of the visual cycle
NZ552080A (en)	2004-06-18	2011-03-31	Univ Washington	9-cis-retinyl esters and uses thereof
KR100862930B1 (ko)	2004-06-23	2008-10-13	시리온 테라퓨틱스, 인크.	레티닐 유도체를 사용하여 안 증상을 치료하기 위한 방법및 조성물
US20060240098A1 (en)	2004-07-14	2006-10-26	Aphios Corporation	Formulations for hyperforin-enriched hypericum fractions
JP2008515778A (ja)	2004-08-18	2008-05-15	シリオンセラピューティクス，インコーポレイテッド	眼の状態を１３−シス−レチニル誘導体で処置するための組み合わせ方法、組成物および治療
WO2006039551A2 (en) *	2004-09-30	2006-04-13	The Regents Of The University Of California	Local administration of retinoids to treat deficiencies in dark adaptation
US20060177392A1 (en)	2005-02-10	2006-08-10	William Walden	Oil-based composition for acne
ES2581212T3 (es)	2005-11-07	2016-09-02	Murty Pharmaceuticals, Inc.	Administración mejorada de tetahidrocannabinol
US8202541B2 (en)	2006-02-07	2012-06-19	U.S. Nutraceuticals, LLC	Dietary supplement composition for blood lipid health
WO2008013983A2 (en)	2006-07-27	2008-01-31	University Of Florida Research Foundation, Inc.	Opsin stabilizing compounds and methods of use
CN109503446B (zh)	2007-01-15	2021-08-20	于崇曦	维生素a酸类和类维生素a酸化合物的前药
EP2687208A1 (en)	2007-09-12	2014-01-22	The Trustees of Columbia University in the City of New York	Compositions and Methods for Treating Macular Degeneration
MX337656B (es)	2008-02-11	2016-03-14	Univ Washington	Metodos para el tratamiento y prevencion de disfuncion retinal relacionada con la edad.
MX2012003220A (es)	2009-09-15	2012-08-03	Quadra Logic Tech Inc	Formulaciones farmaceuticas que comprenden 9-cis-retinil esteres en un vehiculo de lipido.
FR2955459B1 (fr)	2010-01-28	2013-11-22	Polaris	Composition huileuse riche en monoglycerides de dha
KR101851249B1 (ko) *	2010-04-19	2018-06-20	노벨리언 테라퓨틱스 인코포레이티드	내인성 레티노이드 결핍과 연관된 시각 장애의 치료 또는 완화를 위한 치료용 조성물, 제형 및 키트
US20150038582A1 (en)	2012-03-01	2015-02-05	Qlt Inc.	Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency
KR102133608B1 (ko)	2012-03-01	2020-07-13	레티나제닉스, 엘엘씨	내인성 레티노이드 결핍증과 관련된 시각 장애에서 시각 기능의 개선을 위한 치료 요법 및 방법
JP6340525B2 (ja)	2013-11-25	2018-06-13	株式会社デンソー	モータアクチュエータ

2013
- 2013-03-01 KR KR1020147027749A patent/KR102133608B1/ko not_active Expired - Fee Related
- 2013-03-01 PT PT137609434T patent/PT2819667T/pt unknown
- 2013-03-01 ES ES13760943T patent/ES2780357T3/es active Active
- 2013-03-01 NZ NZ629267A patent/NZ629267A/en not_active IP Right Cessation
- 2013-03-01 CN CN201811054761.XA patent/CN109248163A/zh active Pending
- 2013-03-01 AU AU2013232697A patent/AU2013232697B2/en active Active
- 2013-03-01 MX MX2020000225A patent/MX389866B/es unknown
- 2013-03-01 EP EP13760943.4A patent/EP2819667B8/en active Active
- 2013-03-01 JP JP2014559050A patent/JP6576636B2/ja active Active
- 2013-03-01 CN CN201380022484.3A patent/CN104470511A/zh active Pending
- 2013-03-01 BR BR112014021602A patent/BR112014021602A2/pt not_active Application Discontinuation
- 2013-03-01 RU RU2014139666A patent/RU2635536C2/ru active
- 2013-03-01 CA CA2865935A patent/CA2865935C/en active Active
- 2013-03-01 WO PCT/CA2013/050155 patent/WO2013134867A1/en not_active Ceased
- 2013-03-01 MX MX2014010457A patent/MX370928B/es active IP Right Grant
- 2013-03-01 DK DK13760943.4T patent/DK2819667T3/da active
2014
- 2014-08-26 IL IL234306A patent/IL234306B/en unknown
2016
- 2016-04-11 US US15/096,048 patent/US20160296478A1/en not_active Abandoned
2017
- 2017-08-15 JP JP2017156807A patent/JP2017197588A/ja active Pending
2018
- 2018-01-18 AU AU2018200415A patent/AU2018200415B2/en not_active Expired - Fee Related
- 2018-06-11 US US16/005,155 patent/US10828267B2/en active Active
2019
- 2019-12-20 AU AU2019283995A patent/AU2019283995B2/en not_active Ceased
2020
- 2020-02-10 JP JP2020020391A patent/JP2020073597A/ja active Pending

Also Published As

Publication number	Publication date
BR112014021602A2 (pt)	2021-06-08
KR102133608B1 (ko)	2020-07-13
MX2014010457A (es)	2015-04-08
US20160296478A1 (en)	2016-10-13
JP2015508783A (ja)	2015-03-23
AU2018200415A1 (en)	2018-02-08
KR20150000881A (ko)	2015-01-05
MX389866B (es)	2025-03-20
JP6576636B2 (ja)	2019-09-18
CN109248163A (zh)	2019-01-22
JP2020073597A (ja)	2020-05-14
EP2819667A1 (en)	2015-01-07
EP2819667B8 (en)	2020-03-04
CA2865935A1 (en)	2013-09-19
MX370928B (es)	2020-01-08
AU2019283995A1 (en)	2020-01-23
JP2017197588A (ja)	2017-11-02
EP2819667A4 (en)	2015-08-05
US20190054039A1 (en)	2019-02-21
HK1205469A1 (en)	2015-12-18
AU2013232697B2 (en)	2017-10-19
EP2819667B1 (en)	2019-12-25
PT2819667T (pt)	2020-03-31
AU2019283995B2 (en)	2021-11-11
CA2865935C (en)	2021-12-14
IL234306B (en)	2022-02-01
ES2780357T3 (es)	2020-08-25
CN104470511A (zh)	2015-03-25
US10828267B2 (en)	2020-11-10
RU2635536C2 (ru)	2017-11-13
WO2013134867A1 (en)	2013-09-19
AU2013232697A1 (en)	2014-09-18
AU2018200415B2 (en)	2019-09-26
NZ629267A (en)	2016-11-25
RU2014139666A (ru)	2016-04-20

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