DK2841402T3 - Markerede quinoxalinderivater som multimodale radiofarmaceutiske midler og deres prækursorer - Google Patents
Markerede quinoxalinderivater som multimodale radiofarmaceutiske midler og deres prækursorer Download PDFInfo
- Publication number
- DK2841402T3 DK2841402T3 DK13725814.1T DK13725814T DK2841402T3 DK 2841402 T3 DK2841402 T3 DK 2841402T3 DK 13725814 T DK13725814 T DK 13725814T DK 2841402 T3 DK2841402 T3 DK 2841402T3
- Authority
- DK
- Denmark
- Prior art keywords
- precursors
- marked
- pharmaceutical agents
- radio pharmaceutical
- multimodal
- Prior art date
Links
- 239000002243 precursor Substances 0.000 title 1
- XSCHRSMBECNVNS-UHFFFAOYSA-N quinoxaline Chemical class N1=CC=NC2=CC=CC=C21 XSCHRSMBECNVNS-UHFFFAOYSA-N 0.000 title 1
- 239000012217 radiopharmaceutical Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12165413.1A EP2657213A1 (en) | 2012-04-24 | 2012-04-24 | Labelled quinoxaline derivatives as multimodal radiopharmaceuticals and their precursors |
| PCT/IB2013/053106 WO2013160808A1 (en) | 2012-04-24 | 2013-04-19 | Labelled quinoxaline derivatives as multimodal radiopharmaceuticals and their precursors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2841402T3 true DK2841402T3 (da) | 2017-02-20 |
Family
ID=48536968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13725814.1T DK2841402T3 (da) | 2012-04-24 | 2013-04-19 | Markerede quinoxalinderivater som multimodale radiofarmaceutiske midler og deres prækursorer |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20150079000A1 (da) |
| EP (2) | EP2657213A1 (da) |
| AU (1) | AU2013254326B2 (da) |
| DK (1) | DK2841402T3 (da) |
| ES (1) | ES2616793T3 (da) |
| IL (1) | IL235122A (da) |
| WO (1) | WO2013160808A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102014112747A1 (de) * | 2014-09-04 | 2016-03-10 | Eberhard Karls Universität Tübingen Medizinische Fakultät | Verwendung eines Quinoxalinderivats in einem bildgebenden Verfahren |
| JP7339692B2 (ja) * | 2019-03-29 | 2023-09-06 | 国立研究開発法人量子科学技術研究開発機構 | 放射性標識化合物の製造方法及び製造装置 |
| GB201915206D0 (en) | 2019-10-21 | 2019-12-04 | Ge Healthcare Ltd | Use of cyclodextrins as a radiostabilizer |
| JP7668480B2 (ja) * | 2021-01-19 | 2025-04-25 | 国立大学法人東京科学大学 | 放射性ハロゲン標識前駆体化合物 |
| GB202108605D0 (en) * | 2021-06-16 | 2021-07-28 | Ge Healthcare Uk Ltd | Effect of water content |
| WO2025108921A1 (en) * | 2023-11-22 | 2025-05-30 | Institut National de la Santé et de la Recherche Médicale | Synthesis of radiopharmaceutical agents |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2642972B1 (fr) | 1989-02-14 | 1994-08-05 | Inst Nat Sante Rech Med | Agents pour le diagnostic et le traitement des melanomes, derives halogenes aromatiques utilisables comme de tels agents et leur preparation |
| US5911970A (en) | 1993-05-06 | 1999-06-15 | Research Corporation Technologies, Inc. | Methods for cancer imaging and therapy using benzamine compounds |
| DE102004011720B4 (de) | 2004-03-10 | 2008-04-03 | Bayer Schering Pharma Aktiengesellschaft | Radiohalogenierte Benzamidderivate und deren Verwendung in der Tumordiagnostik und Tumortherapie |
| GB0428012D0 (en) * | 2004-12-22 | 2005-01-26 | Hammersmith Imanet Ltd | Radiolabelling methods |
| JP2008546804A (ja) * | 2005-06-24 | 2008-12-25 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | 造影剤として用いるためのリガンドの放射性標識ペグ化 |
| EP2085390A1 (en) | 2008-01-31 | 2009-08-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Labelled analogues of halobenzamides as multimodal radiopharmaceuticals and their precursors |
-
2012
- 2012-04-24 EP EP12165413.1A patent/EP2657213A1/en not_active Withdrawn
-
2013
- 2013-04-19 US US14/396,879 patent/US20150079000A1/en not_active Abandoned
- 2013-04-19 AU AU2013254326A patent/AU2013254326B2/en active Active
- 2013-04-19 DK DK13725814.1T patent/DK2841402T3/da active
- 2013-04-19 ES ES13725814.1T patent/ES2616793T3/es active Active
- 2013-04-19 WO PCT/IB2013/053106 patent/WO2013160808A1/en not_active Ceased
- 2013-04-19 EP EP13725814.1A patent/EP2841402B1/en active Active
-
2014
- 2014-10-19 IL IL235122A patent/IL235122A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013160808A1 (en) | 2013-10-31 |
| HK1207852A1 (en) | 2016-02-12 |
| EP2657213A1 (en) | 2013-10-30 |
| AU2013254326B2 (en) | 2017-02-02 |
| EP2841402B1 (en) | 2016-11-30 |
| ES2616793T3 (es) | 2017-06-14 |
| EP2841402A1 (en) | 2015-03-04 |
| IL235122A (en) | 2017-01-31 |
| US20150079000A1 (en) | 2015-03-19 |
| AU2013254326A1 (en) | 2014-10-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY2022027I2 (el) | Παραγωγα βενζιμιδαζολο-προλινης | |
| DK3608325T3 (da) | Polycykliske-carbamoylpyridonforbindelser og deres farmaceutiske anvendelse | |
| DK3149001T3 (da) | Hidtil ukendte pyrazolopyrimidinderivater og deres anvendelse som MALT1-hæmmere | |
| DK2841429T3 (da) | Tetrazolinonforbindelser og anvendelse deraf som pesticider | |
| DK2903600T3 (da) | Virusholdig formulering og anvendelse deraf | |
| DK3415157T3 (da) | N-acyldipeptidderivater og anvendelser deraf | |
| PL2854858T3 (pl) | Formulacja rysperydonu w postaci implantu | |
| BR112015002738A2 (pt) | composto , e , composição farmacêutica | |
| DK2970187T3 (da) | 4-amino-6-(heterocycliske)picolinater og deres anvendelse som herbicider | |
| DK3597644T3 (da) | Kationiske aminlipider og anvendelser deraf | |
| HRP20181628T1 (hr) | Spojevi i postupci za njihovu upotrebu | |
| DK2900645T3 (da) | Herbicidt aktive 3-phenylisoxazolinderivater | |
| DK2861573T3 (da) | Oxathiazin-derivater som antibakterielle og anticancer-stoffer | |
| PT2935269T (pt) | Derivados de pirazolo-pirimidina terapeuticamente activos | |
| DK2917181T3 (da) | Heteroarylderivater og anvendelser deraf | |
| DK3199533T3 (da) | Pyrazolforbindelse og farmaceutisk anvendelse deraf | |
| DK3392252T3 (da) | Pyrimido-pyridazinonforbindelser og deres anvendelse | |
| DK2966079T3 (da) | Pyridopyrimidin eller pyridopyrimidinforbindelse, fremgangsmåde til fremstilling, farmaceutisk sammensætning og anvendelse deraf | |
| DK2897594T3 (da) | Farmaceutisk sammensætning | |
| CO6910193A2 (es) | Derivados de anilina, su preparación y su aplicación terapéutica | |
| CL2014003283A1 (es) | Formulación farmacéutica. | |
| EP2818015A4 (en) | Managing wireless area networks | |
| EP2860233A4 (en) | PUNCTURE CLOSURE MEANS | |
| DK2875016T3 (da) | Carbamat-/urinstofderivater | |
| DK2877736T3 (da) | Skrue, skruedel og fremgangsmåde dertil |