DK2877200T3 - O-bundne carbonhydratmodificerede insulinanaloger - Google Patents

O-bundne carbonhydratmodificerede insulinanaloger

Info

Publication number
DK2877200T3
DK2877200T3 DK13820520.8T DK13820520T DK2877200T3 DK 2877200 T3 DK2877200 T3 DK 2877200T3 DK 13820520 T DK13820520 T DK 13820520T DK 2877200 T3 DK2877200 T3 DK 2877200T3
Authority
DK
Denmark
Prior art keywords
insulin analogues
linked carbohydrate
modified insulin
carbohydrate modified
linked
Prior art date
Application number
DK13820520.8T
Other languages
English (en)
Inventor
Michael Weiss
Original Assignee
Univ Case Western Reserve
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Case Western Reserve filed Critical Univ Case Western Reserve
Application granted granted Critical
Publication of DK2877200T3 publication Critical patent/DK2877200T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK13820520.8T 2012-07-17 2013-07-17 O-bundne carbonhydratmodificerede insulinanaloger DK2877200T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261672711P 2012-07-17 2012-07-17
US201261693997P 2012-08-28 2012-08-28
PCT/US2013/050955 WO2014015078A1 (en) 2012-07-17 2013-07-17 O-linked carbohydrate-modified insulin analogues

Publications (1)

Publication Number Publication Date
DK2877200T3 true DK2877200T3 (da) 2019-08-12

Family

ID=49949236

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13820520.8T DK2877200T3 (da) 2012-07-17 2013-07-17 O-bundne carbonhydratmodificerede insulinanaloger

Country Status (3)

Country Link
EP (1) EP2877200B1 (da)
DK (1) DK2877200T3 (da)
WO (1) WO2014015078A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3270949B1 (en) * 2015-03-13 2025-01-29 Case Western Reserve University Insulin analogues containing a glucose-regulated conformational switch
WO2017070617A1 (en) * 2015-10-21 2017-04-27 Case Western Reserve University Diol-modified insulin analogues containing a glucose-regulated conformational switch
IL296090A (en) * 2020-03-02 2022-11-01 Thermalin Inc Compositions containing rapid-acting insulin analogues

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990001038A1 (en) 1988-07-20 1990-02-08 Nordisk Gentofte A/S Human insulin analogs and preparations containing them
DK111489D0 (da) * 1989-03-08 1989-03-08 Novo Nordisk As Peptider
US5474978A (en) 1994-06-16 1995-12-12 Eli Lilly And Company Insulin analog formulations
US5679515A (en) 1994-10-03 1997-10-21 Pathogenesis Corporation Mycobacterial reporter strains and uses thereof
US7396903B2 (en) * 2001-11-19 2008-07-08 Novo Nordisk A/S Process for preparing insulin compounds
ES2575984T3 (es) * 2004-11-12 2016-07-04 Novo Nordisk A/S Formulaciones estables de péptidos que contienen un análogo de GLP-1 acilado y una insulina basal
CA2703830A1 (en) * 2007-11-20 2009-05-28 Ambrx, Inc. Modified insulin polypeptides and their uses
PL219335B1 (pl) * 2008-07-04 2015-04-30 Inst Biotechnologii I Antybiotyków Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, jej zastosowanie oraz zawierająca ją kompozycja farmaceutyczna
US20120184488A1 (en) * 2009-09-01 2012-07-19 Case Western Reserve University Insulin analogues of enhanced receptor-binding specificity
US8399407B2 (en) * 2009-09-17 2013-03-19 Case Western Reserve University Non-standard insulin analogues
MX2015005662A (es) * 2012-11-05 2015-08-20 Univ Case Western Reserve Analogos de insulina de una sola cadena de larga accion.

Also Published As

Publication number Publication date
WO2014015078A1 (en) 2014-01-23
EP2877200A4 (en) 2016-03-09
EP2877200B1 (en) 2019-05-08
EP2877200A1 (en) 2015-06-03

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