DK2886A - Dopamin-beta-hydroxylaseinhibitorer - Google Patents

Dopamin-beta-hydroxylaseinhibitorer Download PDF

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Publication number
DK2886A
DK2886A DK2886A DK2886A DK2886A DK 2886 A DK2886 A DK 2886A DK 2886 A DK2886 A DK 2886A DK 2886 A DK2886 A DK 2886A DK 2886 A DK2886 A DK 2886A
Authority
DK
Denmark
Prior art keywords
alkyl
hydroxylase
dopamine beta
hydrogen
co2c1
Prior art date
Application number
DK2886A
Other languages
English (en)
Other versions
DK2886D0 (da
Inventor
Carl Kaiser
Lawrence Ivan Kruse
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK2886D0 publication Critical patent/DK2886D0/da
Publication of DK2886A publication Critical patent/DK2886A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10—Radicals substituted by halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK2886A 1985-01-08 1986-01-03 Dopamin-beta-hydroxylaseinhibitorer DK2886A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/689,680 US4728741A (en) 1985-01-08 1985-01-08 1-substituted-2-mercapto benzimidazole compounds and intermediates

Publications (2)

Publication Number Publication Date
DK2886D0 DK2886D0 (da) 1986-01-03
DK2886A true DK2886A (da) 1986-07-09

Family

ID=24769487

Family Applications (1)

Application Number Title Priority Date Filing Date
DK2886A DK2886A (da) 1985-01-08 1986-01-03 Dopamin-beta-hydroxylaseinhibitorer

Country Status (12)

Country Link
US (1) US4728741A (da)
EP (1) EP0190817B1 (da)
JP (1) JPS61161267A (da)
AT (1) ATE56207T1 (da)
AU (2) AU588562B2 (da)
CA (1) CA1269668A (da)
DE (1) DE3673835D1 (da)
DK (1) DK2886A (da)
ES (1) ES8703844A1 (da)
GR (1) GR860018B (da)
PT (1) PT81786B (da)
ZA (1) ZA8665B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61151176A (ja) * 1984-12-24 1986-07-09 Sumitomo Chem Co Ltd ベンズイミダゾール誘導体およびそれを有効成分とする殺虫、殺ダニ剤
JPS63101380A (ja) * 1986-10-17 1988-05-06 Zeria Shinyaku Kogyo Kk 新規な２−メルカプトベンズイミダゾ−ル誘導体、それらの製造法およびそれらを有効成分として含有する抗潰瘍剤
IT1226100B (it) * 1988-07-07 1990-12-10 Dompe Farmaceutici Spa Derivati benzimidazolici farmacologicamente attivi.
GB8904174D0 (en) * 1989-02-23 1989-04-05 British Bio Technology Compounds
EP0515535A4 (en) * 1990-02-13 1996-01-17 Merck & Co Inc Angiotensin ii antagonists incorporating a substituted benzyl element
US5106863A (en) * 1990-03-26 1992-04-21 Ortho Pharmaceutical Corporation Substituted imidazole and pyridine derivatives
EP0474109A1 (de) * 1990-09-03 1992-03-11 Richter Gedeon Vegyeszeti Gyar R.T. Neue 5-Benzyl-substituierte Benzimidazolin-2-Thion-Derivate und Verfahren zu ihrer Herstellung
GB9101448D0 (en) * 1991-01-23 1991-03-06 Cox John H Improved door assembly
TW300219B (da) * 1991-09-14 1997-03-11 Hoechst Ag
US6114532A (en) * 1998-02-03 2000-09-05 Boehringer Ingelheim Pharma Kg Bicyclic heterocycles, the preparation thereof, and their use as pharmaceuticals
US20060148805A1 (en) * 2003-07-01 2006-07-06 Meng Hsin Chen Opthalmic compositions for treating ocular hypertension
DE102007037579B4 (de) * 2007-08-09 2012-05-16 Emc Microcollections Gmbh Neue Benzimidazol-2-yl-alkylamine und ihre Anwendung als mikrobizide Wirkstoffe
JOP20190050A1 (ar) * 2016-09-23 2019-03-20 Bial Portela & C? S A مثبطات دوبامين-b-هيدروكسيلاز تخترق حاجز المخ الدموي

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL302847A (da) * 1963-01-10
DE1542886A1 (de) * 1966-10-04 1970-05-14 Bayer Ag Fungizide Mittel
BE732508A (da) * 1968-05-08 1969-10-16
DE2235093C2 (de) * 1972-07-18 1974-07-04 Bayer Ag, 5090 Leverkusen Korrosionsschutzmittel
FR2521141A1 (fr) * 1982-02-09 1983-08-12 Rhone Poulenc Agrochimie Nouveaux derives du cyano-2 benzimidazole, leur preparation et leur utilisation comme fongicides
US4492708A (en) * 1982-09-27 1985-01-08 Eli Lilly And Company Antiviral benzimidazoles
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
EP0269230A1 (en) * 1986-10-09 1988-06-01 The Wellcome Foundation Limited Heterocyclic compounds

Also Published As

Publication number Publication date
US4728741A (en) 1988-03-01
ES8703844A1 (es) 1987-03-01
AU3788789A (en) 1989-10-19
CA1269668A (en) 1990-05-29
AU588562B2 (en) 1989-09-21
DE3673835D1 (de) 1990-10-11
ZA8665B (en) 1986-08-27
ATE56207T1 (de) 1990-09-15
PT81786B (pt) 1988-05-27
ES550699A0 (es) 1987-03-01
GR860018B (en) 1986-04-29
JPS61161267A (ja) 1986-07-21
EP0190817B1 (en) 1990-09-05
DK2886D0 (da) 1986-01-03
EP0190817A1 (en) 1986-08-13
AU5180186A (en) 1986-07-17
PT81786A (en) 1986-02-01

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AHS Application shelved for other reasons than non-payment