DK294986A - 7-(substitueret amino)-8-((substitueret carbonyl)-methylamino)-1-oxaspiro(4.5)decaner - Google Patents
7-(substitueret amino)-8-((substitueret carbonyl)-methylamino)-1-oxaspiro(4.5)decaner Download PDFInfo
- Publication number
- DK294986A DK294986A DK294986A DK294986A DK294986A DK 294986 A DK294986 A DK 294986A DK 294986 A DK294986 A DK 294986A DK 294986 A DK294986 A DK 294986A DK 294986 A DK294986 A DK 294986A
- Authority
- DK
- Denmark
- Prior art keywords
- substituted
- decaner
- oxaspiro
- methylamino
- carbonyl
- Prior art date
Links
- -1 AMINO Chemical class 0.000 title 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75036585A | 1985-07-01 | 1985-07-01 | |
| US06/870,611 US4737493A (en) | 1985-07-01 | 1986-06-09 | 7-((substituted)amino)-8-((substituted)carbonyl)-methylamino)-1-oxaspiro(4,5)decanes as analgesic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK294986D0 DK294986D0 (da) | 1986-06-23 |
| DK294986A true DK294986A (da) | 1987-01-02 |
Family
ID=27115265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK294986A DK294986A (da) | 1985-07-01 | 1986-06-23 | 7-(substitueret amino)-8-((substitueret carbonyl)-methylamino)-1-oxaspiro(4.5)decaner |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4737493A (fr) |
| EP (1) | EP0207773B1 (fr) |
| JP (1) | JPH072731B2 (fr) |
| AU (1) | AU578837B2 (fr) |
| CA (1) | CA1264321A (fr) |
| DE (1) | DE3667974D1 (fr) |
| DK (1) | DK294986A (fr) |
| ES (1) | ES2000297A6 (fr) |
| HK (1) | HK26194A (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4855316A (en) * | 1988-02-18 | 1989-08-08 | Warner-Lambert Company | 1,2-diamino-4,5-dimethoxycyclohexyl amide analgesic compounds |
| US5051428A (en) * | 1988-12-06 | 1991-09-24 | Warner-Lambert Company | 2-amino-4 or 5-methoxycyclohexyl amides useful as analgesics |
| US4906655A (en) * | 1989-01-24 | 1990-03-06 | Warner-Lambert Company | Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents |
| US4965278A (en) * | 1989-04-21 | 1990-10-23 | Warner-Lambert Company | 7-(substituted)amino)-8-((substituted)carbonyl)-methylamino)-1-oxaspiro[4,5]decanes as diuretics antiiflammatory, and cerebrovascular agents |
| US5063242A (en) * | 1989-04-21 | 1991-11-05 | Warner-Lambert Company | 7-((substituted)amino)-8-((substituted)carbonyl)-methylamino-1-oxaspiro[4,5]decanes as diuretics antiinflammatory, and cerebrovascular agents |
| US5506257A (en) * | 1992-03-26 | 1996-04-09 | University Of British Columbia | Aminocyclohexylamides for antiarrhythmic and anaesthetic uses |
| EP0632806B1 (fr) * | 1992-03-26 | 1997-07-02 | The University Of British Columbia | Aminocyclohexylamides destines a des utilisations antiarythmiques et anesthesiques |
| US5317028A (en) * | 1992-09-08 | 1994-05-31 | Warner-Lambert Co. | 7-((substituted)amino)-8((substituted)carbonyl)-methylamino-1-oxaspiro(4,5)decanes useful in Parkinson's disease, dystonia, and other movement disorders |
| US5369120A (en) * | 1993-07-28 | 1994-11-29 | Warner-Lambert Company | Pharmaceutical composition of 7-((substituted)amino-8-((substituted)carbonyl)-(methylamino)-1-oxasp iro(4,5)decanes and L-dopa |
| DE69429524T2 (de) | 1993-09-24 | 2002-08-08 | The University Of British Columbia, Vancouver | Aminocyclohexylester und ihre anwendung |
| US5489607A (en) * | 1995-02-16 | 1996-02-06 | Warner-Lambert Company | Use of enadoline in the treatment of benign prostatic enlargement |
| USRE38133E1 (en) * | 1996-03-08 | 2003-06-03 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| US6057323A (en) * | 1996-03-08 | 2000-05-02 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
| US5763445A (en) * | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
| US5688955A (en) * | 1996-03-08 | 1997-11-18 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| US5646151A (en) * | 1996-03-08 | 1997-07-08 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| US6057357A (en) * | 1997-04-30 | 2000-05-02 | Warner-Lambert Company | Peripherally selective kappa opioid agonists |
| WO1998049158A1 (fr) * | 1997-04-30 | 1998-11-05 | Warner-Lambert Company | Kappa agonistes opioides peripheriquement selectifs |
| US7053087B1 (en) * | 1999-03-04 | 2006-05-30 | Cardiome Pharma Corp. | Aminocycloalkyl cinnamide compounds for arrhythmia and analgesics and anesthetics |
| AU2002322720B2 (en) | 2001-07-25 | 2008-11-13 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| CA2789262C (fr) | 2005-04-28 | 2016-10-04 | Proteus Digital Health, Inc. | Systeme pharma-informatique |
| EP2063905B1 (fr) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Traitement des troubles hépatiques par l'administration de conjugués de protéine associée au récepteur (rap) |
| TR201908314T4 (tr) | 2009-02-20 | 2019-06-21 | 2 Bbb Medicines B V | Glutatyon bazlı ilaç dağıtım sistemi. |
| KR101909711B1 (ko) | 2009-05-06 | 2018-12-19 | 라보라토리 스킨 케어, 인크. | 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| JP7734917B2 (ja) | 2019-01-28 | 2025-09-08 | ミトコンドリア エモーション， インク． | トランス－４－ヒドロキシシクロヘキシルフェニルアミドマイトフュージン活性化物質及びその使用方法 |
| AU2019427489B2 (en) | 2019-01-28 | 2025-03-13 | Mitochondria Emotion, Inc. | Mitofusin activators and methods of use thereof |
| JPWO2023277116A1 (fr) * | 2021-06-30 | 2023-01-05 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4065573A (en) * | 1976-06-03 | 1977-12-27 | The Upjohn Company | 4-Amino-4-phenylcyclohexanone ketal compositions and process of use |
| US4145435A (en) * | 1976-11-12 | 1979-03-20 | The Upjohn Company | 2-aminocycloaliphatic amide compounds |
| US4098904A (en) * | 1976-11-12 | 1978-07-04 | The Upjohn Company | Analgesic n-(2-aminocycloaliphatic)benzamides |
| US4212878A (en) * | 1978-01-26 | 1980-07-15 | The Upjohn Company | Phenylacetamide derivative analgesics |
| US4359476A (en) * | 1981-04-09 | 1982-11-16 | The Upjohn Company | Adjacently substituted cycloalkane-amide analgesics |
| US4360531A (en) * | 1981-04-09 | 1982-11-23 | The Upjohn Company | Substituted cycloalkanes |
| US4438130A (en) * | 1981-11-12 | 1984-03-20 | The Upjohn Company | Analgesic 1-oxa-, aza- and thia-spirocyclic compounds |
| CA1242195A (fr) * | 1983-07-18 | 1988-09-20 | David K. Herron | Inhibiteurs de leucotrienes |
| US4598087A (en) * | 1983-12-06 | 1986-07-01 | Warner-Lambert Company | Substituted trans-1,2-diaminocyclohexyl amide compounds |
-
1986
- 1986-06-09 US US06/870,611 patent/US4737493A/en not_active Expired - Lifetime
- 1986-06-23 AU AU59194/86A patent/AU578837B2/en not_active Ceased
- 1986-06-23 DK DK294986A patent/DK294986A/da not_active Application Discontinuation
- 1986-06-26 CA CA000512571A patent/CA1264321A/fr not_active Expired - Fee Related
- 1986-06-30 DE DE8686305071T patent/DE3667974D1/de not_active Expired - Fee Related
- 1986-06-30 EP EP86305071A patent/EP0207773B1/fr not_active Expired - Lifetime
- 1986-06-30 JP JP61151856A patent/JPH072731B2/ja not_active Expired - Fee Related
- 1986-07-01 ES ES8600068A patent/ES2000297A6/es not_active Expired
-
1994
- 1994-03-24 HK HK261/94A patent/HK26194A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3667974D1 (de) | 1990-02-08 |
| EP0207773B1 (fr) | 1990-01-03 |
| JPS6259271A (ja) | 1987-03-14 |
| JPH072731B2 (ja) | 1995-01-18 |
| DK294986D0 (da) | 1986-06-23 |
| EP0207773A2 (fr) | 1987-01-07 |
| EP0207773A3 (en) | 1987-11-04 |
| AU578837B2 (en) | 1988-11-03 |
| AU5919486A (en) | 1987-01-08 |
| CA1264321A (fr) | 1990-01-09 |
| US4737493A (en) | 1988-04-12 |
| HK26194A (en) | 1994-03-31 |
| ES2000297A6 (es) | 1988-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |