DK2952513T3 - Azolbenzenderivat - Google Patents

Azolbenzenderivat Download PDF

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Publication number
DK2952513T3
DK2952513T3 DK14746209.7T DK14746209T DK2952513T3 DK 2952513 T3 DK2952513 T3 DK 2952513T3 DK 14746209 T DK14746209 T DK 14746209T DK 2952513 T3 DK2952513 T3 DK 2952513T3
Authority
DK
Denmark
Prior art keywords
azolbenzender
derivative
azolbenzender derivative
Prior art date
Application number
DK14746209.7T
Other languages
English (en)
Inventor
Asahi Kawana
Chikashi Kanazawa
Yoshimasa Takahashi
Takashi Shirakura
Original Assignee
Teijin Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51262388&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2952513(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd
Application granted granted Critical
Publication of DK2952513T3 publication Critical patent/DK2952513T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK14746209.7T 2013-01-31 2014-01-30 Azolbenzenderivat DK2952513T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013017167 2013-01-31
PCT/JP2014/052154 WO2014119681A1 (ja) 2013-01-31 2014-01-30 アゾールベンゼン誘導体

Publications (1)

Publication Number Publication Date
DK2952513T3 true DK2952513T3 (da) 2019-09-02

Family

ID=51262388

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14746209.7T DK2952513T3 (da) 2013-01-31 2014-01-30 Azolbenzenderivat

Country Status (36)

Country Link
US (1) US9388174B2 (da)
EP (1) EP2952513B1 (da)
JP (1) JP5734532B2 (da)
KR (1) KR102199258B1 (da)
CN (1) CN104968662B (da)
AR (1) AR095098A1 (da)
AU (1) AU2014213396B2 (da)
BR (1) BR112015018033B1 (da)
CA (1) CA2897928C (da)
CL (1) CL2015002117A1 (da)
CY (1) CY1122015T1 (da)
DK (1) DK2952513T3 (da)
ES (1) ES2744817T3 (da)
HR (1) HRP20191554T1 (da)
HU (1) HUE047028T2 (da)
IL (2) IL239940B (da)
LT (1) LT2952513T (da)
MA (1) MA38295B1 (da)
ME (1) ME03516B (da)
MX (1) MX364483B (da)
MY (1) MY181731A (da)
NZ (1) NZ709407A (da)
PE (1) PE20151329A1 (da)
PH (2) PH12015501640A1 (da)
PL (1) PL2952513T3 (da)
PT (1) PT2952513T (da)
RS (1) RS59371B1 (da)
RU (1) RU2641891C2 (da)
SA (1) SA515360829B1 (da)
SG (1) SG11201505993PA (da)
SI (1) SI2952513T1 (da)
SM (1) SMT201900577T1 (da)
TW (1) TWI606048B (da)
UA (1) UA117124C2 (da)
WO (1) WO2014119681A1 (da)
ZA (1) ZA201505240B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105026373B (zh) 2013-01-31 2018-03-30 沃泰克斯药物股份有限公司 作为钠通道调节剂的吡啶酮酰胺
SG11201604477SA (en) 2013-12-13 2016-07-28 Vertex Pharma Prodrugs of pyridone amides useful as modulators of sodium channels
US20170217948A1 (en) 2014-07-30 2017-08-03 Teijin Pharma Limited Xanthine oxidase inhibitor
LT3176166T (lt) * 2014-07-30 2019-01-10 Teijin Pharma Limited Azolbenzeno dariniai ir jų kristalai
CN106536519B (zh) * 2014-07-30 2019-03-29 帝人制药株式会社 唑苯衍生物的晶体
JP6732004B2 (ja) * 2016-02-19 2020-07-29 国立大学法人鳥取大学 認知症治療薬または予防薬
TW201828939A (zh) 2016-11-28 2018-08-16 日商帝人製藥股份有限公司 糖尿病性腎病之治療藥或預防藥
KR102714561B1 (ko) 2017-05-16 2024-10-10 버텍스 파마슈티칼스 인코포레이티드 나트륨 채널의 조절제로서의 중수소화 피리돈 아미드 및 이의 프로드럭
US20190343817A1 (en) 2018-02-12 2019-11-14 Vertex Pharmaceuticals Incorporated Method of treating pain
PH12022551379A1 (en) 2019-12-06 2023-05-03 Vertex Pharma Substituted tetrahydrofurans as modulators of sodium channels
SI4347031T1 (sl) 2021-06-04 2026-01-30 Vertex Pharmaceuticals Incorporated N-(hidroksialkil (hetero)aril) tetrahidrofuran karboksamidi kot modulatorji natrijevih kanalčkov
US12030866B2 (en) * 2021-12-23 2024-07-09 Springworks Therapeutics, Inc. 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2073981C (en) 1990-11-30 2002-01-08 Shiro Kondo 2-arylthiazole derivatives and pharmaceutical composition thereof
US5843969A (en) * 1995-04-07 1998-12-01 Teijin Limited Protecting agent for organ or tissue
CA2218493C (en) * 1995-04-21 2005-02-22 Neurosearch A/S Benzimidazole compounds and their use as modulators of the gabaa receptor complex
JP2002105067A (ja) 2000-09-28 2002-04-10 Teijin Ltd 2−フェニルチアゾール誘導体、およびそれを有効成分とする医薬組成物
CA2623327A1 (en) 2005-10-07 2007-04-19 Kissei Pharmaceutical Co., Ltd. Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same
WO2008126770A1 (ja) 2007-04-05 2008-10-23 Astellas Pharma Inc. トリアリールカルボン酸誘導体の製造方法
MX2009010491A (es) 2007-04-11 2009-11-09 Kissei Pharmaceutical Derivado heterociclico de 5 miembros y su uso para propositos medicos.
WO2010018458A2 (en) 2008-08-12 2010-02-18 Crystalgenomics, Inc. Phenol derivatives and methods of use thereof
WO2010128163A2 (en) 2009-05-08 2010-11-11 Pike Pharma Gmbh Small molecule inhibitors of influenza a and b virus and respiratory syncytial virus replication
WO2011101867A2 (en) 2010-02-19 2011-08-25 Cadila Healthcare Limited Substantially pure salts of febuxostat and processes for preparation thereof
US8969582B2 (en) 2010-04-29 2015-03-03 Dr. Reddy's Laboratories Ltd. Preparation of febuxostat

Also Published As

Publication number Publication date
US9388174B2 (en) 2016-07-12
KR102199258B1 (ko) 2021-01-06
KR20150112955A (ko) 2015-10-07
NZ709407A (en) 2019-09-27
MY181731A (en) 2021-01-05
ME03516B (me) 2020-04-20
CA2897928A1 (en) 2014-08-07
EP2952513A4 (en) 2015-12-09
PH12015501640B1 (en) 2015-10-12
TWI606048B (zh) 2017-11-21
ES2744817T3 (es) 2020-02-26
PL2952513T3 (pl) 2020-01-31
MX364483B (es) 2019-04-26
IL239940A0 (en) 2015-08-31
RU2641891C2 (ru) 2018-01-23
AR095098A1 (es) 2015-09-30
PT2952513T (pt) 2019-09-27
SI2952513T1 (sl) 2019-08-30
EP2952513B1 (en) 2019-07-10
HK1215806A1 (zh) 2016-09-15
IL239940B (en) 2018-07-31
LT2952513T (lt) 2019-10-25
CA2897928C (en) 2021-02-16
AU2014213396A1 (en) 2015-07-23
SA515360829B1 (ar) 2018-10-11
HRP20191554T1 (hr) 2019-11-29
PE20151329A1 (es) 2015-10-12
MA38295A1 (fr) 2017-12-29
CL2015002117A1 (es) 2015-10-30
RS59371B1 (sr) 2019-11-29
RU2015132105A (ru) 2017-02-03
CN104968662B (zh) 2018-03-30
AU2014213396B2 (en) 2017-05-11
EP2952513A1 (en) 2015-12-09
US20150376174A1 (en) 2015-12-31
CN104968662A (zh) 2015-10-07
IL259824A (en) 2018-07-31
BR112015018033A8 (pt) 2019-11-05
PH12018500261A1 (en) 2018-09-10
TW201443047A (zh) 2014-11-16
PH12015501640A1 (en) 2015-10-12
IL259824B (en) 2020-04-30
UA117124C2 (uk) 2018-06-25
JP5734532B2 (ja) 2015-06-17
WO2014119681A1 (ja) 2014-08-07
SMT201900577T1 (it) 2019-11-13
MA38295B1 (fr) 2018-04-30
PH12018500261B1 (en) 2018-09-10
CY1122015T1 (el) 2020-10-14
JPWO2014119681A1 (ja) 2017-01-26
ZA201505240B (en) 2016-08-31
MX2015009655A (es) 2015-12-07
SG11201505993PA (en) 2015-08-28
BR112015018033B1 (pt) 2023-02-14
BR112015018033A2 (pt) 2017-07-11
HUE047028T2 (hu) 2020-04-28

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