DK2989200T3 - Fremgangsmåder til at opnå retinaprogenitorer, retinapigmenterede epitelceller og neurale retinaceller - Google Patents
Fremgangsmåder til at opnå retinaprogenitorer, retinapigmenterede epitelceller og neurale retinaceller Download PDFInfo
- Publication number
- DK2989200T3 DK2989200T3 DK14726419.6T DK14726419T DK2989200T3 DK 2989200 T3 DK2989200 T3 DK 2989200T3 DK 14726419 T DK14726419 T DK 14726419T DK 2989200 T3 DK2989200 T3 DK 2989200T3
- Authority
- DK
- Denmark
- Prior art keywords
- retina
- cells
- pigentized
- epitle
- progenitors
- Prior art date
Links
- 210000001525 retina Anatomy 0.000 title 2
- 238000000034 method Methods 0.000 title 1
- 210000005157 neural retina Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/062—Sensory transducers, e.g. photoreceptors; Sensory neurons, e.g. for hearing, taste, smell, pH, touch, temperature, pain
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/42—Notch; Delta; Jagged; Serrate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2527/00—Culture process characterised by the use of mechanical forces, e.g. strain, vibration
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Neurology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Acoustics & Sound (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Developmental Biology & Embryology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20130165654 EP2796545A1 (en) | 2013-04-26 | 2013-04-26 | Methods for obtaining retinal progenitors, retinal pigmented epithelial cells and neural retinal cells |
| PCT/IB2014/061010 WO2014174492A1 (en) | 2013-04-26 | 2014-04-25 | Methods for obtaining retinal progenitors, retinal pigmented epithelial cells and neural retinal cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2989200T3 true DK2989200T3 (da) | 2021-04-26 |
Family
ID=48190294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14726419.6T DK2989200T3 (da) | 2013-04-26 | 2014-04-25 | Fremgangsmåder til at opnå retinaprogenitorer, retinapigmenterede epitelceller og neurale retinaceller |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9994815B2 (da) |
| EP (2) | EP2796545A1 (da) |
| JP (1) | JP6482005B2 (da) |
| KR (1) | KR102146007B1 (da) |
| CN (1) | CN105492596B (da) |
| AU (1) | AU2014258981B2 (da) |
| CA (1) | CA2909851C (da) |
| DK (1) | DK2989200T3 (da) |
| ES (1) | ES2868360T3 (da) |
| IL (1) | IL242224B (da) |
| PT (1) | PT2989200T (da) |
| WO (1) | WO2014174492A1 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL281453B (en) | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
| US11241460B2 (en) | 2013-03-15 | 2022-02-08 | Astellas Institute For Regenerative Medicine | Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells |
| EP4292600A3 (en) | 2013-03-15 | 2024-04-10 | Astellas Institute for Regenerative Medicine | Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells |
| US10584314B2 (en) * | 2014-08-08 | 2020-03-10 | National Center For Child Health And Development | Method for preparation of retinal ganglion cells |
| CN106318909B (zh) * | 2015-06-23 | 2019-04-05 | 何伟 | 一种具有治疗视网膜退行性病变功能的视网膜祖细胞及其制剂 |
| WO2017219062A1 (en) * | 2016-06-23 | 2017-12-28 | The University Of Sydney | Methods for differentiating cells into cells with a muller cell phenotype, cells produced by the methods, and methods for using the cells |
| KR102638492B1 (ko) * | 2017-02-17 | 2024-02-19 | 쏘흐본느 유니베흐시테 | 망막 전구 세포, 망막 색소 상피 세포 및 신경 망막 세포를 얻기 위한 피더-비의존적(Feeder-free) 방법 |
| GB201703058D0 (en) * | 2017-02-24 | 2017-04-12 | Ucl Business Plc | Biomarkers |
| CN109423480B (zh) * | 2017-12-21 | 2022-04-12 | 中山大学中山眼科中心 | 一种人多能干细胞分化为视网膜组织的简易高效可机械化的诱导方法 |
| CN109988750A (zh) * | 2017-12-29 | 2019-07-09 | 江苏艾尔康生物医药科技有限公司 | 一种视网膜色素上皮细胞的培养方法 |
| US12497591B2 (en) | 2018-03-07 | 2025-12-16 | Sorbonne Universite | Compositions and methods for efficient amplification of retinal progenitors cells |
| JP2021521792A (ja) | 2018-04-20 | 2021-08-30 | フジフィルム セルラー ダイナミクス，インコーポレイテッド | 眼球細胞の分化方法及びその使用 |
| CN108795864B (zh) * | 2018-05-24 | 2021-08-24 | 中山大学中山眼科中心 | 一种利用人诱导多能干细胞获得富含视锥及视杆细胞的类视网膜组织的方法 |
| CA3132804A1 (en) * | 2019-03-13 | 2020-09-17 | Sumitomo Dainippon Pharma Co., Ltd. | Method for evaluating quality of transplant neural retina, and transplant neural retina sheet |
| EP3969570A1 (en) * | 2019-05-15 | 2022-03-23 | Novo Nordisk A/S | Methods for obtaining eye field progenitor cells from human pluripotent stem cells |
| EP4110899A4 (en) * | 2020-02-28 | 2024-03-20 | Riken | METHOD FOR PREPARING A RETINAL PIGMENT EPITHELIAL CELL |
| FR3125538B1 (fr) * | 2021-07-22 | 2024-01-19 | Centre Detude Des Cellules Souches Cecs | Echafaudage microstructure pour la preparation d’un implant tissulaire |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE464373T1 (de) * | 2001-12-21 | 2010-04-15 | Mount Sinai Hospital Corp | Zelluläre zusammensetzungen und verfahren zur deren bereitung und verwendung |
| DE602004024529D1 (de) * | 2003-06-11 | 2010-01-21 | Japan Science & Tech Agency | Verfahren zur herstellung eines retinalen neurozyten aus einer von irisgewebe abgeleiteten stammzelle sowie mit dem verfahren hergestellter retinaler neurozyt |
| EP2929782A1 (en) * | 2004-01-23 | 2015-10-14 | Ocata Therapeutics, Inc. | Improved modalities for the treatment of degenerative diseases of the retina |
| US8481313B2 (en) * | 2008-04-22 | 2013-07-09 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| EP2470645B1 (en) * | 2009-08-24 | 2019-06-26 | Wisconsin Alumni Research Foundation | Substantially pure human retinal progenitor, forebrain progenitor, and retinal pigment epithelium cell cultures and methods of making the same |
| IL281453B (en) * | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
| ES2542226T3 (es) * | 2010-04-28 | 2015-08-03 | Technische Universität Dresden | Método para producir células progenitoras retinianas polarizadas a partir de células madre pluripotentes y su diferenciación para dar células del epitelio pigmentario retiniano |
| FI20106354A0 (fi) * | 2010-12-20 | 2010-12-20 | Suomen Punainen Risti Veripalvelu | Menetelmä ihmisen retinan pigmentti-epiteelisolujen valmistamiseksi |
-
2013
- 2013-04-26 EP EP20130165654 patent/EP2796545A1/en not_active Withdrawn
-
2014
- 2014-04-25 JP JP2016509595A patent/JP6482005B2/ja active Active
- 2014-04-25 US US14/786,427 patent/US9994815B2/en active Active
- 2014-04-25 ES ES14726419T patent/ES2868360T3/es active Active
- 2014-04-25 CN CN201480029524.1A patent/CN105492596B/zh active Active
- 2014-04-25 KR KR1020157033001A patent/KR102146007B1/ko active Active
- 2014-04-25 WO PCT/IB2014/061010 patent/WO2014174492A1/en not_active Ceased
- 2014-04-25 EP EP14726419.6A patent/EP2989200B1/en active Active
- 2014-04-25 DK DK14726419.6T patent/DK2989200T3/da active
- 2014-04-25 PT PT147264196T patent/PT2989200T/pt unknown
- 2014-04-25 AU AU2014258981A patent/AU2014258981B2/en active Active
- 2014-04-25 CA CA2909851A patent/CA2909851C/en active Active
-
2015
- 2015-10-22 IL IL242224A patent/IL242224B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ES2868360T3 (es) | 2021-10-21 |
| EP2989200B1 (en) | 2021-01-20 |
| KR20160002969A (ko) | 2016-01-08 |
| JP6482005B2 (ja) | 2019-03-13 |
| PT2989200T (pt) | 2021-04-26 |
| US20160060596A1 (en) | 2016-03-03 |
| EP2989200A1 (en) | 2016-03-02 |
| US9994815B2 (en) | 2018-06-12 |
| CN105492596A (zh) | 2016-04-13 |
| CA2909851C (en) | 2021-11-09 |
| AU2014258981B2 (en) | 2019-12-05 |
| EP2796545A1 (en) | 2014-10-29 |
| CN105492596B (zh) | 2020-03-17 |
| CA2909851A1 (en) | 2014-10-30 |
| IL242224B (en) | 2020-03-31 |
| KR102146007B1 (ko) | 2020-08-19 |
| JP2016516434A (ja) | 2016-06-09 |
| AU2014258981A1 (en) | 2015-12-03 |
| WO2014174492A1 (en) | 2014-10-30 |
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