DK2989239T4 - Selektion af Fab-fragmenter ved anvendelse af ribosomfremvisningsteknologi - Google Patents

Selektion af Fab-fragmenter ved anvendelse af ribosomfremvisningsteknologi Download PDF

Info

Publication number: DK2989239T4
Authority: DK; Denmark
Prior art keywords: selection; fab fragments; display technology; ribosome display; ribosome
Prior art date: 2013-04-25

Application number

DK14788445.6T

Other languages

English (en)

Other versions

DK2989239T3 (da

Inventor

Ryan Stafford

Christopher D Thanos

Original Assignee

Sutro Biopharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-04-25

Filing date

2014-04-23

Publication date

2025-04-07

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51792506&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2989239(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2014-04-23 Application filed by Sutro Biopharma Inc filed Critical Sutro Biopharma Inc

2018-09-03 Application granted granted Critical

2018-09-03 Publication of DK2989239T3 publication Critical patent/DK2989239T3/da

2025-04-07 Publication of DK2989239T4 publication Critical patent/DK2989239T4/da

Links

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Cell Biology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Peptides Or Proteins (AREA)

DK14788445.6T 2013-04-25 2014-04-23 Selektion af Fab-fragmenter ved anvendelse af ribosomfremvisningsteknologi DK2989239T4 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201361816075P	2013-04-25	2013-04-25
PCT/US2014/035130 WO2014176327A2 (en)	2013-04-25	2014-04-23	Selection of fab fragments using ribosomal display technology

Publications (2)

Publication Number	Publication Date
DK2989239T3 DK2989239T3 (da)	2018-09-03
DK2989239T4 true DK2989239T4 (da)	2025-04-07

Family

ID=51792506

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK14788445.6T DK2989239T4 (da)	2013-04-25	2014-04-23	Selektion af Fab-fragmenter ved anvendelse af ribosomfremvisningsteknologi

Country Status (4)

Country	Link
US (1)	US20160069897A1 (da)
EP (1)	EP2989239B2 (da)
DK (1)	DK2989239T4 (da)
WO (1)	WO2014176327A2 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2657334B1 (en)	2012-04-26	2016-07-06	GeneFrontier Corporation	Efficient method for displaying protein multimer
EP2989202B1 (en)	2013-04-25	2019-04-10	Sutro Biopharma, Inc.	The use of lambda-gam protein in ribosomal display technology
WO2018156777A1 (en)	2017-02-22	2018-08-30	Sutro Biopharma, Inc.	Pd-1/tim-3 bi-specific antibodies, compositions thereof, and methods of making and using the same
EP3630292A2 (en)	2017-05-24	2020-04-08	Sutro Biopharma, Inc.	Pd-1/lag3 bi-specific antibodies, compositions thereof, and methods of making and using the same
WO2023019144A1 (en) *	2021-08-10	2023-02-16	The Regents Of The University Of California	Hla-a2-specific regulatory t cells

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5922545A (en) *	1993-10-29	1999-07-13	Affymax Technologies N.V.	In vitro peptide and antibody display libraries
DE69834032T2 (de)	1997-04-23	2006-12-07	Universität Zürich	Verfahren zur erkennung von nucleinsäuremolekülen codierend für (poly)peptide, welche mit zielmolekülen interagieren
ES2253358T3 (es) *	2000-03-31	2006-06-01	Cambridge Antibody Technology Limited	Mejoras en la visualizacion del ribosoma.
US20040067532A1 (en) *	2002-08-12	2004-04-08	Genetastix Corporation	High throughput generation and affinity maturation of humanized antibody
ATE445699T1 (de)	2002-08-19	2009-10-15	Univ Leland Stanford Junior	Verbesserte verfahren zur in-vitro- proteinsynthese
US20080275219A1 (en) *	2004-06-21	2008-11-06	The Johns Hopkins University	In Vitro Reconstitution of Ribonucleoprotein Complexes, and Methods of Use Therefor
JP4939410B2 (ja) *	2004-07-06	2012-05-23	バイオレン，インク．	強化された特性を持つ変性ポリペプチドを発生させるためのルックスルー変異誘発
US7351563B2 (en)	2005-06-10	2008-04-01	The Board Of Trustees Of The Leland Stanford Junior University	Cell-free extracts and synthesis of active hydrogenase
DK2356270T3 (da) *	2008-11-07	2016-12-12	Fabrus Llc	Kombinatoriske antistofbiblioteker og anvendelser deraf
CN102348807B (zh)	2009-01-12	2015-04-15	苏特罗生物制药公司	利用体外蛋白合成体系将非天然氨基酸引入蛋白的单装载体系
EP2647704B1 (en) *	2010-12-01	2017-11-01	Mitsubishi Tanabe Pharma Corporation	Polynucleotide construct capable of presenting fab in acellular translation system, and method for manufacturing and screening fab using same
EP2657334B1 (en)	2012-04-26	2016-07-06	GeneFrontier Corporation	Efficient method for displaying protein multimer

2014
- 2014-04-23 US US14/786,804 patent/US20160069897A1/en not_active Abandoned
- 2014-04-23 EP EP14788445.6A patent/EP2989239B2/en active Active
- 2014-04-23 DK DK14788445.6T patent/DK2989239T4/da active
- 2014-04-23 WO PCT/US2014/035130 patent/WO2014176327A2/en not_active Ceased

Also Published As

Publication number	Publication date
EP2989239B1 (en)	2018-07-04
US20160069897A1 (en)	2016-03-10
EP2989239B2 (en)	2025-01-15
EP2989239A2 (en)	2016-03-02
WO2014176327A3 (en)	2014-12-31
DK2989239T3 (da)	2018-09-03
EP2989239A4 (en)	2016-11-16
WO2014176327A2 (en)	2014-10-30

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EP3525454C0 (en)	2025-02-26	DISPLAY DEVICE
HUE052125T2 (hu)	2021-04-28	Billenõ csukló
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EP3054159A4 (en)	2016-09-28	COMPRESSOR
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EP2980406A4 (en)	2016-11-09	COMPRESSOR
UA27558S (uk)	2014-08-11	Лінза
DK2989239T4 (da)	2025-04-07	Selektion af Fab-fragmenter ved anvendelse af ribosomfremvisningsteknologi
FR3005670B1 (fr)	2015-12-18	Panneau de construction bois-beton