DK2992104T3 - Fremgangsmåde til ekspression - Google Patents

Fremgangsmåde til ekspression Download PDF

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Publication number
DK2992104T3
DK2992104T3 DK14721474.6T DK14721474T DK2992104T3 DK 2992104 T3 DK2992104 T3 DK 2992104T3 DK 14721474 T DK14721474 T DK 14721474T DK 2992104 T3 DK2992104 T3 DK 2992104T3
Authority
DK
Denmark
Prior art keywords
expression procedure
expression
procedure
Prior art date
Application number
DK14721474.6T
Other languages
English (en)
Inventor
Fay Louise Saunders
Anna Louise Dodds
Adeline Marie Geraldine Bayard
Bhupendra Vallabh Kara
Original Assignee
Fujifilm Diosynth Biotechnologies Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB201308017A external-priority patent/GB201308017D0/en
Priority claimed from GB201320339A external-priority patent/GB201320339D0/en
Application filed by Fujifilm Diosynth Biotechnologies Uk Ltd filed Critical Fujifilm Diosynth Biotechnologies Uk Ltd
Application granted granted Critical
Publication of DK2992104T3 publication Critical patent/DK2992104T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3092—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
DK14721474.6T 2013-05-03 2014-04-29 Fremgangsmåde til ekspression DK2992104T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201308017A GB201308017D0 (en) 2013-05-03 2013-05-03 Expression process
GB201320339A GB201320339D0 (en) 2013-11-18 2013-11-18 Expression Process
PCT/GB2014/000165 WO2014177826A1 (en) 2013-05-03 2014-04-29 Expression process

Publications (1)

Publication Number Publication Date
DK2992104T3 true DK2992104T3 (da) 2019-07-15

Family

ID=50639794

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14721474.6T DK2992104T3 (da) 2013-05-03 2014-04-29 Fremgangsmåde til ekspression

Country Status (12)

Country Link
US (3) US9873891B2 (da)
EP (1) EP2992104B1 (da)
JP (1) JP6545153B2 (da)
KR (1) KR102180660B1 (da)
CN (2) CN105392889A (da)
BR (1) BR112015027373A2 (da)
CA (1) CA2910877C (da)
DK (1) DK2992104T3 (da)
ES (1) ES2732907T3 (da)
RU (1) RU2731717C2 (da)
SG (1) SG11201508447TA (da)
WO (1) WO2014177826A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3323826A1 (en) * 2016-11-21 2018-05-23 Danmarks Tekniske Universitet Native chinese hamster ovary cell secretion signal peptides for production of recombinant polypeptides
CN111465686B (zh) 2017-12-11 2024-03-22 富士胶片株式会社 动物细胞、动物细胞的制造方法及靶蛋白的制造方法
CN113242907B (zh) 2018-12-11 2025-01-07 富士胶片株式会社 动物细胞、动物细胞的制造方法及靶蛋白的制造方法
CN109837277A (zh) * 2019-03-01 2019-06-04 深圳生生凡非基因技术有限公司 一种cpgk嵌合型启动子、腺相关病毒载体及其应用
JP7352650B2 (ja) 2019-11-29 2023-09-28 富士フイルム株式会社 細胞培養方法、抗体製造方法、有機酸除去方法、及び、抗体
JPWO2022149607A1 (da) 2021-01-07 2022-07-14
EP4310175A1 (en) 2021-03-17 2024-01-24 FUJIFILM Corporation Cell culturing method, and method for producing useful substance
CN112980852B (zh) * 2021-05-18 2021-08-13 北京华芢生物技术有限公司 新型冠状病毒b.1.351南非突变株rbd的基因及其应用
WO2022249089A1 (en) 2021-05-27 2022-12-01 Janssen Biotech, Inc. Compositions and methods for the treatment of prostate cancer
JPWO2023054556A1 (da) 2021-09-30 2023-04-06
JPWO2023112952A1 (da) 2021-12-15 2023-06-22
EP4502169A4 (en) 2022-03-28 2025-12-31 Fujifilm Corp PRODUCT PRODUCTION PROCESS AND PRODUCT
JPWO2023190829A1 (da) 2022-03-31 2023-10-05
EP4538379A1 (en) * 2022-06-10 2025-04-16 Fujifilm Diosynth Biotechnologies UK Limited Method for producing cells, method for producing heteromultimeric protein, method for producing bispecific antibody, and method for producing vector set, mammalian cells, cho cells, and cell pool
EP4596704A4 (en) 2022-09-29 2026-03-11 Fujifilm Corp PRODUCT PRODUCTION PROCESS
EP4722338A1 (en) 2023-05-31 2026-04-08 FUJIFILM Corporation Cell culture method and product producing method
EP4722378A1 (en) 2023-05-31 2026-04-08 FUJIFILM Corporation Method for producing product
CN121285635A (zh) 2023-05-31 2026-01-06 富士胶片株式会社 生产物的生产方法
WO2025244971A1 (en) 2024-05-20 2025-11-27 Janssen Biotech, Inc. Compositions and methods for the treatment of prostate cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7071172B2 (en) * 2002-04-30 2006-07-04 The University Of North Carolina At Chapel Hill Secretion signal vectors
US7186699B2 (en) * 2003-06-03 2007-03-06 Cell Genesys, Inc. Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes
US8029783B2 (en) * 2005-02-02 2011-10-04 Genentech, Inc. DR5 antibodies and articles of manufacture containing same
EP1739179A1 (en) * 2005-06-30 2007-01-03 Octapharma AG Serum-free stable transfection and production of recombinant human proteins in human cell lines
GB0602173D0 (en) * 2006-02-03 2006-03-15 Avecia Ltd Expression system
CN101646775B (zh) * 2006-12-28 2016-08-24 森托科尔奥索生物科技公司 用于产生脱唾液酸化免疫球蛋白的方法和载体
KR101618767B1 (ko) * 2008-09-02 2016-05-09 한국생명공학연구원 외래단백질을 고효율로 생산하는 리더서열
ES2692173T3 (es) * 2008-12-31 2018-11-30 Bharat Serums And Vaccines Ltd. Anticuerpos monoclonales anti-RHD
EP2403531A4 (en) 2009-03-05 2013-02-27 Abbott Lab IL-17 BINDING PROTEINS
GB0905331D0 (en) * 2009-03-27 2009-05-13 Avecia Biolog Ltd Expression process
KR101420274B1 (ko) * 2011-06-13 2014-07-21 주식회사 종근당 Ｃｓｐ－ｂ ５＇ｓａｒ 인자를 포함하는 동물세포 발현 벡터 및 이를 이용한 재조합 단백질의 제조방법

Also Published As

Publication number Publication date
EP2992104A1 (en) 2016-03-09
KR20160003705A (ko) 2016-01-11
US11306323B2 (en) 2022-04-19
US20160076051A1 (en) 2016-03-17
JP6545153B2 (ja) 2019-07-17
US20220213500A1 (en) 2022-07-07
CA2910877C (en) 2021-08-03
KR102180660B1 (ko) 2020-11-19
CN114395584A (zh) 2022-04-26
RU2015151626A (ru) 2017-06-08
RU2015151626A3 (da) 2018-03-20
CA2910877A1 (en) 2014-11-06
EP2992104B1 (en) 2019-04-17
RU2731717C2 (ru) 2020-09-08
US20180127777A1 (en) 2018-05-10
US9873891B2 (en) 2018-01-23
CN114395584B (zh) 2025-01-28
JP2016517691A (ja) 2016-06-20
SG11201508447TA (en) 2015-11-27
CN105392889A (zh) 2016-03-09
ES2732907T3 (es) 2019-11-26
WO2014177826A1 (en) 2014-11-06
BR112015027373A2 (pt) 2017-08-29

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