DK3008213T3 - Detektion af protein-til-protein-interaktioner - Google Patents

Detektion af protein-til-protein-interaktioner Download PDF

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Publication number
DK3008213T3
DK3008213T3 DK14810600.8T DK14810600T DK3008213T3 DK 3008213 T3 DK3008213 T3 DK 3008213T3 DK 14810600 T DK14810600 T DK 14810600T DK 3008213 T3 DK3008213 T3 DK 3008213T3
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DK
Denmark
Prior art keywords
protein
detection
interactions
protein interactions
Prior art date
Application number
DK14810600.8T
Other languages
English (en)
Inventor
Igor Stagljar
Julia Petschnigg
Bella Groisman
Original Assignee
Governing Council Univ Toronto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Governing Council Univ Toronto filed Critical Governing Council Univ Toronto
Application granted granted Critical
Publication of DK3008213T3 publication Critical patent/DK3008213T3/da

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1055Protein x Protein interaction, e.g. two hybrid selection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK14810600.8T 2013-06-10 2014-06-10 Detektion af protein-til-protein-interaktioner DK3008213T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361833304P 2013-06-10 2013-06-10
PCT/CA2014/050539 WO2014197986A1 (en) 2013-06-10 2014-06-10 Detection of protein to protein interactions

Publications (1)

Publication Number Publication Date
DK3008213T3 true DK3008213T3 (da) 2020-08-24

Family

ID=52021527

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14810600.8T DK3008213T3 (da) 2013-06-10 2014-06-10 Detektion af protein-til-protein-interaktioner

Country Status (6)

Country Link
US (1) US9958461B2 (da)
EP (1) EP3008213B1 (da)
CA (1) CA2914980C (da)
DK (1) DK3008213T3 (da)
ES (1) ES2811874T3 (da)
WO (1) WO2014197986A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11718849B2 (en) 2018-02-19 2023-08-08 Agilent Technologies, Inc. Phosphopeptide-encoding oligonucleotide libraries and methods for detecting phosphorylation-dependent molecular interactions
GB201909491D0 (en) * 2019-07-01 2019-08-14 Governing Council Of The Univ Of Toronto Detection of protein to protein interactions
EP4077399A4 (en) * 2019-12-17 2024-03-06 Orionis Biosciences, Inc. DETECTION OF MOLECULAR INTERACTIONS
WO2024011360A1 (zh) * 2022-07-11 2024-01-18 清华大学 基于生存压力的筛选系统及高通量筛选装置
WO2024259644A1 (zh) * 2023-06-21 2024-12-26 清华大学 一种融合蛋白的组合物、包含其的基于生存压力的负向筛选系统

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1325148A1 (en) * 2000-09-29 2003-07-09 Universität Zürich Method and kit for detecting membrane protein - protein interactions
DE60216721T2 (de) 2002-03-28 2007-10-18 Dualsystems Biotech Ag Verfahren zum Nachweis von Protein-Proteininteraktionen in Membranen
EP1808495A1 (en) * 2006-01-12 2007-07-18 Dualsystems Biotech AG Method and kit for detecting interactions between transcriptionally active proteins
US8617549B2 (en) * 2009-09-11 2013-12-31 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Bispecific nanobodies as a therapeutic for alzheimer's disease

Also Published As

Publication number Publication date
WO2014197986A1 (en) 2014-12-18
EP3008213A4 (en) 2017-02-22
US9958461B2 (en) 2018-05-01
CA2914980C (en) 2019-03-26
ES2811874T3 (es) 2021-03-15
US20160124000A1 (en) 2016-05-05
EP3008213B1 (en) 2020-07-15
EP3008213A1 (en) 2016-04-20
CA2914980A1 (en) 2014-12-18

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