DK3008213T3 - Detektion af protein-til-protein-interaktioner - Google Patents
Detektion af protein-til-protein-interaktioner Download PDFInfo
- Publication number
- DK3008213T3 DK3008213T3 DK14810600.8T DK14810600T DK3008213T3 DK 3008213 T3 DK3008213 T3 DK 3008213T3 DK 14810600 T DK14810600 T DK 14810600T DK 3008213 T3 DK3008213 T3 DK 3008213T3
- Authority
- DK
- Denmark
- Prior art keywords
- protein
- detection
- interactions
- protein interactions
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title 1
- 230000003993 interaction Effects 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Endocrinology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361833304P | 2013-06-10 | 2013-06-10 | |
| PCT/CA2014/050539 WO2014197986A1 (en) | 2013-06-10 | 2014-06-10 | Detection of protein to protein interactions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3008213T3 true DK3008213T3 (da) | 2020-08-24 |
Family
ID=52021527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14810600.8T DK3008213T3 (da) | 2013-06-10 | 2014-06-10 | Detektion af protein-til-protein-interaktioner |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9958461B2 (da) |
| EP (1) | EP3008213B1 (da) |
| CA (1) | CA2914980C (da) |
| DK (1) | DK3008213T3 (da) |
| ES (1) | ES2811874T3 (da) |
| WO (1) | WO2014197986A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11718849B2 (en) | 2018-02-19 | 2023-08-08 | Agilent Technologies, Inc. | Phosphopeptide-encoding oligonucleotide libraries and methods for detecting phosphorylation-dependent molecular interactions |
| GB201909491D0 (en) * | 2019-07-01 | 2019-08-14 | Governing Council Of The Univ Of Toronto | Detection of protein to protein interactions |
| EP4077399A4 (en) * | 2019-12-17 | 2024-03-06 | Orionis Biosciences, Inc. | DETECTION OF MOLECULAR INTERACTIONS |
| WO2024011360A1 (zh) * | 2022-07-11 | 2024-01-18 | 清华大学 | 基于生存压力的筛选系统及高通量筛选装置 |
| WO2024259644A1 (zh) * | 2023-06-21 | 2024-12-26 | 清华大学 | 一种融合蛋白的组合物、包含其的基于生存压力的负向筛选系统 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1325148A1 (en) * | 2000-09-29 | 2003-07-09 | Universität Zürich | Method and kit for detecting membrane protein - protein interactions |
| DE60216721T2 (de) | 2002-03-28 | 2007-10-18 | Dualsystems Biotech Ag | Verfahren zum Nachweis von Protein-Proteininteraktionen in Membranen |
| EP1808495A1 (en) * | 2006-01-12 | 2007-07-18 | Dualsystems Biotech AG | Method and kit for detecting interactions between transcriptionally active proteins |
| US8617549B2 (en) * | 2009-09-11 | 2013-12-31 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University | Bispecific nanobodies as a therapeutic for alzheimer's disease |
-
2014
- 2014-06-10 CA CA2914980A patent/CA2914980C/en active Active
- 2014-06-10 DK DK14810600.8T patent/DK3008213T3/da active
- 2014-06-10 WO PCT/CA2014/050539 patent/WO2014197986A1/en not_active Ceased
- 2014-06-10 ES ES14810600T patent/ES2811874T3/es active Active
- 2014-06-10 EP EP14810600.8A patent/EP3008213B1/en active Active
- 2014-06-10 US US14/897,048 patent/US9958461B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014197986A1 (en) | 2014-12-18 |
| EP3008213A4 (en) | 2017-02-22 |
| US9958461B2 (en) | 2018-05-01 |
| CA2914980C (en) | 2019-03-26 |
| ES2811874T3 (es) | 2021-03-15 |
| US20160124000A1 (en) | 2016-05-05 |
| EP3008213B1 (en) | 2020-07-15 |
| EP3008213A1 (en) | 2016-04-20 |
| CA2914980A1 (en) | 2014-12-18 |
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