DK302190D0 - Fremgangsmaade til behandling af neurologiske tilstande - Google Patents

Fremgangsmaade til behandling af neurologiske tilstande

Info

Publication number
DK302190D0
DK302190D0 DK302190A DK302190A DK302190D0 DK 302190 D0 DK302190 D0 DK 302190D0 DK 302190 A DK302190 A DK 302190A DK 302190 A DK302190 A DK 302190A DK 302190 D0 DK302190 D0 DK 302190D0
Authority
DK
Denmark
Prior art keywords
neurological conditions
treating neurological
chem
compositions
disclosed
Prior art date
Application number
DK302190A
Other languages
English (en)
Other versions
DK302190A (da
Inventor
Joel G Berger
Wei K Chang
Elijah H Gold
John W Clader
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DK302190D0 publication Critical patent/DK302190D0/da
Publication of DK302190A publication Critical patent/DK302190A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK302190A 1988-07-18 1990-12-20 Fremgangsmaade til behandling af neurologiske tilstande DK302190A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/223,739 US4973586A (en) 1986-01-16 1988-07-18 Fused benzazepines, compositions of, and medical use thereof
PCT/US1989/002997 WO1990000853A2 (en) 1988-07-18 1989-07-14 Method of treating neurological disorders

Publications (2)

Publication Number Publication Date
DK302190D0 true DK302190D0 (da) 1990-12-20
DK302190A DK302190A (da) 1991-01-11

Family

ID=22837795

Family Applications (1)

Application Number Title Priority Date Filing Date
DK302190A DK302190A (da) 1988-07-18 1990-12-20 Fremgangsmaade til behandling af neurologiske tilstande

Country Status (13)

Country Link
US (1) US4973586A (da)
EP (2) EP0351733B1 (da)
JP (1) JPH0662420B2 (da)
KR (1) KR900701275A (da)
AT (1) ATE131056T1 (da)
AU (1) AU634973B2 (da)
CA (1) CA1336823C (da)
DE (1) DE68925004T2 (da)
DK (1) DK302190A (da)
ES (1) ES2080736T3 (da)
IL (1) IL90973A (da)
WO (1) WO1990000853A2 (da)
ZA (1) ZA895343B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
US5091526A (en) * 1988-07-29 1992-02-25 Schering Corporation Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
CA2016465A1 (en) * 1989-06-02 1990-12-02 Zola Phillip Horovitz Method for preventing or treating anxiety employing a calcium channel blocker
AU646432B2 (en) * 1990-02-02 1994-02-24 Schering Corporation 4,5-cycloalkano-3-benzazepin-7-ol-derivatives and their use
US5312819A (en) * 1990-08-20 1994-05-17 Sandoz Ltd. Pharmaceutical compositions comprising clozapine and a radical scavenger
US5461148A (en) * 1993-09-27 1995-10-24 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5461147A (en) * 1993-09-27 1995-10-24 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5463051A (en) * 1993-09-27 1995-10-31 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
WO1999015161A2 (en) * 1997-09-24 1999-04-01 The General Hospital Corporation Inhibition of psychostimulant-induced and nicotine-induced craving
US6410527B1 (en) 1998-03-02 2002-06-25 Schering Corporation Method of treating obsessive compulsive disorders, somatoform disorders, dissociative disorders, eating disorders, impulse control disorders, and autism
US6875866B2 (en) * 2002-02-21 2005-04-05 Schering Corporation Process for synthesis of D1 receptor antagonists
EP1537115B1 (en) * 2002-08-29 2008-05-28 Schering Corporation Selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders
CA2526017A1 (en) * 2003-05-22 2005-04-21 Schering Corporation 5-h-benzo[d]naphth[2,1-b]azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders
PL2872145T3 (pl) 2012-07-12 2022-06-20 Emalex Biosciences, Inc. Połączone benzazepiny w leczeniu zespołu tourette’a
LT3057595T (lt) 2013-10-18 2020-08-10 Emalex Biosciences, Inc. Sintezuoti benzazepinai, skirti mikčiojimui gydyti
US12594281B2 (en) 2024-03-15 2026-04-07 Emalex Biosciences, Inc. Pharmaceutical dosage forms and methods of use
WO2025194153A1 (en) 2024-03-15 2025-09-18 Emalex Biosciences, Inc. Pharmaceutical dosage forms and methods of use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
GB1118688A (en) * 1967-02-17 1968-07-03 Scherico Ltd Novel benzazepines and process for making same
CH481110A (de) * 1967-02-17 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
US3609138A (en) * 1967-12-22 1971-09-28 Ciba Geigy Corp 1-aryl-3-benzazepines
NL7206204A (da) * 1971-05-10 1972-11-14
US3983234A (en) * 1974-07-04 1976-09-28 Sandoz Ltd. Treatment of dyskinesias
US3939165A (en) * 1974-11-14 1976-02-17 Morton-Norwich Products, Inc. 5,6,6A,6B,7,8-Hexahydrobenz[a]phenanthridine hydrochloride
US4011319A (en) * 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
US4284555A (en) * 1979-04-27 1981-08-18 Schering Corporation 7-Chloro-8(substituted amino carbonyloxy)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4315926A (en) * 1979-12-26 1982-02-16 Ciba-Geigy Corporation Dibenz[c,e]azepines
US4477378A (en) * 1980-02-05 1984-10-16 Schering Corp. Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
DE3007710C2 (de) * 1980-02-29 1982-04-15 Gödecke AG, 1000 Berlin 5,6;8,9-Tetrahydro-7H-dibenz(d,f)azonin-derivate, Verfahren zu deren Herstellung und Arzneimittel
KR900007781B1 (ko) 1986-01-16 1990-10-20 쉐링 코포레이션 융합된 벤즈아제핀
ZA875183B (en) 1987-07-15 1988-04-08 Schering Corporation Fused benzazepines

Also Published As

Publication number Publication date
ATE131056T1 (de) 1995-12-15
JPH0662420B2 (ja) 1994-08-17
KR900701275A (ko) 1990-12-01
WO1990000853A8 (en) 2005-06-16
JPH03502100A (ja) 1991-05-16
WO1990000853A2 (en) 1990-02-08
CA1336823C (en) 1995-08-29
DK302190A (da) 1991-01-11
EP0434695A1 (en) 1991-07-03
DE68925004T2 (de) 1996-05-15
DE68925004D1 (de) 1996-01-18
US4973586A (en) 1990-11-27
AU3988489A (en) 1990-02-19
AU634973B2 (en) 1993-03-11
EP0351733A1 (en) 1990-01-24
IL90973A (en) 1994-04-12
ZA895343B (en) 1991-03-27
ES2080736T3 (es) 1996-02-16
EP0351733B1 (en) 1995-12-06

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment