DK3050569T3 - Modificeret agrin-fragment til gendannelse af muskel-styrke til brug som medikament - Google Patents

Modificeret agrin-fragment til gendannelse af muskel-styrke til brug som medikament Download PDF

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Publication number
DK3050569T3
DK3050569T3 DK16157895.0T DK16157895T DK3050569T3 DK 3050569 T3 DK3050569 T3 DK 3050569T3 DK 16157895 T DK16157895 T DK 16157895T DK 3050569 T3 DK3050569 T3 DK 3050569T3
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DK
Denmark
Prior art keywords
medicine
recovery
muscle strength
agrin fragment
modified agrin
Prior art date
Application number
DK16157895.0T
Other languages
English (en)
Inventor
Jan Willem Vrijbloed
Stefan Hettwer
Stefan Kucsera
Original Assignee
Neurotune Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurotune Ag filed Critical Neurotune Ag
Application granted granted Critical
Publication of DK3050569T3 publication Critical patent/DK3050569T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK16157895.0T 2009-09-04 2010-09-01 Modificeret agrin-fragment til gendannelse af muskel-styrke til brug som medikament DK3050569T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09011367A EP2295068A1 (en) 2009-09-04 2009-09-04 Modified agrin-fragment capable of restoring muscle strength for use as a medicament
EP10759572.0A EP2473184B1 (en) 2009-09-04 2010-09-01 Modified agrin-fragment capable of restoring muscle strength for use as a medicament

Publications (1)

Publication Number Publication Date
DK3050569T3 true DK3050569T3 (da) 2019-09-02

Family

ID=41278553

Family Applications (2)

Application Number Title Priority Date Filing Date
DK16157895.0T DK3050569T3 (da) 2009-09-04 2010-09-01 Modificeret agrin-fragment til gendannelse af muskel-styrke til brug som medikament
DK10759572.0T DK2473184T3 (da) 2009-09-04 2010-09-01 Modificeret agrin-fragment, der kan genoprette muskelstyrke, til anvendelse som et lægemiddel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK10759572.0T DK2473184T3 (da) 2009-09-04 2010-09-01 Modificeret agrin-fragment, der kan genoprette muskelstyrke, til anvendelse som et lægemiddel

Country Status (15)

Country Link
US (1) US8685915B2 (da)
EP (3) EP2295068A1 (da)
JP (1) JP5752124B2 (da)
KR (1) KR20120060878A (da)
CN (1) CN102481339B (da)
AU (1) AU2010291560B2 (da)
BR (1) BR112012008104B1 (da)
CA (1) CA2769602A1 (da)
DK (2) DK3050569T3 (da)
EA (1) EA026814B1 (da)
ES (2) ES2572835T3 (da)
IL (1) IL217741A0 (da)
MX (1) MX2012001409A (da)
NZ (1) NZ597853A (da)
WO (1) WO2011026615A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2484695A1 (en) * 2011-02-04 2012-08-08 Neurotune AG A method for the production of hybridoma cell lines producing monoclonal antibodies capable to specifically binding to a human C44-fragment of agrin
CN103869078A (zh) * 2014-03-04 2014-06-18 南昌大学 利用聚集蛋白针对神经传递障碍疾病的诊断组合物
US20170306400A1 (en) * 2014-04-03 2017-10-26 Tokyo Metropolitan Geriatric Hospital And Institute Of Gerontology Biomarker for diagnosis of aging or amyotrophia
IL242380A0 (en) 2015-10-29 2016-02-01 Yeda Res & Dev A method of inducing cardiomyocytes proliferation and treating heart diseases
GB201620119D0 (en) * 2016-11-29 2017-01-11 Pharmafox Therapeutics Ag Compounds
WO2018223062A1 (en) * 2017-06-01 2018-12-06 Baylor College Of Medicine Dystrophin glycoprotein complex sequesters yap to inhibit cardiomyocyte proliferation
WO2019106680A1 (en) * 2017-12-03 2019-06-06 Yeda Research And Development Co. Ltd. Treatment of an ischemic heart disease
CN118488952A (zh) * 2021-12-27 2024-08-13 安斯泰来制药有限公司 取代的喹啉衍生物
KR20240151850A (ko) * 2022-03-02 2024-10-18 유니버시타트 바셀 새로운 단백질과 핵산 서열 및 선천성 근이영양증에 대한 이의 예방 및/또는 치료 용도

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5814478A (en) * 1995-12-15 1998-09-29 Regeneron Pharmaceuticals, Inc. Tyrosine kinase receptors and ligands
US20080295186A1 (en) * 1998-04-24 2008-11-27 Peter Sonderegger Neurotrypsin overexpressing animal
EP1868989A2 (en) * 2005-03-30 2007-12-26 University of Zurich Inhibitors of neurotrypsin and determination thereof
WO2008074813A2 (en) * 2006-12-21 2008-06-26 Neurotune Ag Optiogenin for the treatment of neural diseases

Also Published As

Publication number Publication date
MX2012001409A (es) 2012-05-23
CN102481339A (zh) 2012-05-30
JP5752124B2 (ja) 2015-07-22
BR112012008104A2 (pt) 2016-09-13
ES2743239T3 (es) 2020-02-18
CN102481339B (zh) 2015-01-14
EP2295068A1 (en) 2011-03-16
EA201270345A1 (ru) 2012-09-28
EA026814B1 (ru) 2017-05-31
HK1167092A1 (en) 2012-11-23
EP2473184A1 (en) 2012-07-11
NZ597853A (en) 2014-04-30
US20120208765A1 (en) 2012-08-16
JP2013503825A (ja) 2013-02-04
EP3050569B1 (en) 2019-05-29
IL217741A0 (en) 2012-03-29
KR20120060878A (ko) 2012-06-12
BR112012008104B1 (pt) 2019-12-03
EP3050569A1 (en) 2016-08-03
WO2011026615A1 (en) 2011-03-10
AU2010291560B2 (en) 2016-09-29
ES2572835T3 (es) 2016-06-02
DK2473184T3 (da) 2016-06-13
EP2473184B1 (en) 2016-03-02
US8685915B2 (en) 2014-04-01
AU2010291560A1 (en) 2012-02-16
CA2769602A1 (en) 2011-03-10

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