DK305184D0 - Hexahydropyrrolo(2,1-a)isoquinolin-derivater - Google Patents
Hexahydropyrrolo(2,1-a)isoquinolin-derivaterInfo
- Publication number
- DK305184D0 DK305184D0 DK305184A DK305184A DK305184D0 DK 305184 D0 DK305184 D0 DK 305184D0 DK 305184 A DK305184 A DK 305184A DK 305184 A DK305184 A DK 305184A DK 305184 D0 DK305184 D0 DK 305184D0
- Authority
- DK
- Denmark
- Prior art keywords
- hexahydropyrrolo
- derivatives
- isoquinolin
- isoquinolines
- depression
- Prior art date
Links
- UFFWABKYFLFHDG-UHFFFAOYSA-N 1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline Chemical class C1=CC=C2C3CCCN3CCC2=C1 UFFWABKYFLFHDG-UHFFFAOYSA-N 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
- C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50725083A | 1983-06-23 | 1983-06-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK305184D0 true DK305184D0 (da) | 1984-06-22 |
| DK305184A DK305184A (da) | 1984-12-24 |
Family
ID=24017860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK305184A DK305184A (da) | 1983-06-23 | 1984-06-22 | Hexahydropyrrolo(2,1-a)isoquinolin-derivater |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0130069B1 (da) |
| JP (1) | JPS6069082A (da) |
| KR (1) | KR910002564B1 (da) |
| AT (1) | ATE59041T1 (da) |
| AU (1) | AU563990B2 (da) |
| CA (1) | CA1253155A (da) |
| DE (1) | DE3483735D1 (da) |
| DK (1) | DK305184A (da) |
| ES (1) | ES533657A0 (da) |
| FI (1) | FI76798C (da) |
| HK (1) | HK54891A (da) |
| HU (1) | HU193937B (da) |
| NO (1) | NO164474C (da) |
| NZ (1) | NZ208480A (da) |
| SG (1) | SG44391G (da) |
| ZA (1) | ZA844402B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4572911A (en) * | 1984-08-02 | 1986-02-25 | Mcneilab, Inc. | Hexahydroindolinzine compounds, pharmaceutical compositions and methods and intermediates |
| DE3717395A1 (de) * | 1987-05-23 | 1988-12-08 | Basf Ag | 5-phenyl-1,2,3a,4,5,9b-hexahydro-3h-benz(e) indole, ihre herstellung und verwendung als arzneimittel |
| GB8718980D0 (en) * | 1987-08-11 | 1987-09-16 | May & Baker Ltd | Compositions of matter |
| GB9326699D0 (en) * | 1993-12-22 | 1994-03-02 | Celltech Ltd | Chemical compounds |
| CA2612495A1 (en) | 2005-06-17 | 2006-12-28 | Janssen Pharmaceutica N.V. | Hexahydro-pyrrolo-isoquinoline compounds for the treatment of cns disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE690792A (da) * | 1966-12-07 | 1967-05-16 | ||
| CH538477A (de) * | 1970-01-06 | 1973-06-30 | Hoffmann La Roche | Verfahren zur Herstellung von Isochinolin-Derivaten |
-
1984
- 1984-06-11 ZA ZA844402A patent/ZA844402B/xx unknown
- 1984-06-12 NO NO842345A patent/NO164474C/no unknown
- 1984-06-12 NZ NZ208480A patent/NZ208480A/en unknown
- 1984-06-14 CA CA000456578A patent/CA1253155A/en not_active Expired
- 1984-06-21 FI FI842533A patent/FI76798C/fi not_active IP Right Cessation
- 1984-06-22 AU AU29777/84A patent/AU563990B2/en not_active Ceased
- 1984-06-22 HU HU842443A patent/HU193937B/hu not_active IP Right Cessation
- 1984-06-22 DE DE8484304247T patent/DE3483735D1/de not_active Expired - Lifetime
- 1984-06-22 DK DK305184A patent/DK305184A/da unknown
- 1984-06-22 EP EP84304247A patent/EP0130069B1/en not_active Expired - Lifetime
- 1984-06-22 ES ES533657A patent/ES533657A0/es active Granted
- 1984-06-22 AT AT84304247T patent/ATE59041T1/de not_active IP Right Cessation
- 1984-06-23 JP JP59129917A patent/JPS6069082A/ja active Pending
- 1984-06-23 KR KR1019840003577A patent/KR910002564B1/ko not_active Expired
-
1991
- 1991-06-14 SG SG44391A patent/SG44391G/en unknown
- 1991-07-18 HK HK548/91A patent/HK54891A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO164474C (no) | 1990-10-10 |
| ES8602676A1 (es) | 1985-10-01 |
| HK54891A (en) | 1991-07-26 |
| EP0130069B1 (en) | 1990-12-12 |
| NO164474B (no) | 1990-07-02 |
| FI76798C (fi) | 1988-12-12 |
| EP0130069A2 (en) | 1985-01-02 |
| JPS6069082A (ja) | 1985-04-19 |
| HU193937B (en) | 1987-12-28 |
| ES533657A0 (es) | 1985-10-01 |
| DE3483735D1 (en) | 1991-01-24 |
| KR910002564B1 (ko) | 1991-04-26 |
| ZA844402B (en) | 1986-01-29 |
| HUT34478A (en) | 1985-03-28 |
| FI842533A7 (fi) | 1984-12-24 |
| ATE59041T1 (de) | 1990-12-15 |
| FI842533A0 (fi) | 1984-06-21 |
| FI76798B (fi) | 1988-08-31 |
| AU2977784A (en) | 1985-01-03 |
| NO842345L (no) | 1984-12-27 |
| AU563990B2 (en) | 1987-07-30 |
| EP0130069A3 (en) | 1985-09-11 |
| DK305184A (da) | 1984-12-24 |
| CA1253155A (en) | 1989-04-25 |
| KR850000440A (ko) | 1985-02-27 |
| NZ208480A (en) | 1986-08-08 |
| SG44391G (en) | 1991-07-26 |
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