DK3083970T4 - Fremgangsmåde til oprensning af kappebærende virusser eller virale vektorer - Google Patents
Fremgangsmåde til oprensning af kappebærende virusser eller virale vektorer Download PDFInfo
- Publication number
- DK3083970T4 DK3083970T4 DK14828237.9T DK14828237T DK3083970T4 DK 3083970 T4 DK3083970 T4 DK 3083970T4 DK 14828237 T DK14828237 T DK 14828237T DK 3083970 T4 DK3083970 T4 DK 3083970T4
- Authority
- DK
- Denmark
- Prior art keywords
- purification
- procedure
- viral vectors
- enveloped viruses
- enveloped
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- 239000013603 viral vector Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15051—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16051—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1362835A FR3014901B1 (fr) | 2013-12-17 | 2013-12-17 | Procede de purification de virus ou vecteurs viraux enveloppes |
| PCT/FR2014/053406 WO2015092287A1 (fr) | 2013-12-17 | 2014-12-17 | Procédé de purification de virus ou vecteurs viraux enveloppes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3083970T3 DK3083970T3 (da) | 2019-11-11 |
| DK3083970T4 true DK3083970T4 (da) | 2024-06-17 |
Family
ID=50933209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14828237.9T DK3083970T4 (da) | 2013-12-17 | 2014-12-17 | Fremgangsmåde til oprensning af kappebærende virusser eller virale vektorer |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10465169B2 (da) |
| EP (1) | EP3083970B2 (da) |
| JP (1) | JP6553043B2 (da) |
| CN (1) | CN105980571A (da) |
| DK (1) | DK3083970T4 (da) |
| ES (1) | ES2753300T5 (da) |
| FR (1) | FR3014901B1 (da) |
| SG (1) | SG11201605805RA (da) |
| WO (1) | WO2015092287A1 (da) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3010720B1 (fr) | 2013-09-16 | 2017-08-11 | Genethon | Procede de production de virus enveloppes |
| JP7221049B2 (ja) * | 2015-11-19 | 2023-02-13 | ノバルティス アーゲー | レンチウイルス調製物の安定化のための緩衝液 |
| US10358626B2 (en) | 2016-04-12 | 2019-07-23 | Artemis Biosystems, Inc. | Perfusion filtration systems |
| CN108524929B (zh) * | 2017-03-06 | 2019-05-07 | 广州瑞贝斯药业有限公司 | 一种狂犬病疫苗的生产方法 |
| CN107630037A (zh) * | 2017-10-19 | 2018-01-26 | 和元生物技术（上海）股份有限公司 | 一种获得高纯度腺相关病毒载体的纯化工艺 |
| CN110317832B (zh) | 2018-03-28 | 2022-07-05 | 西比曼生物科技（香港）有限公司 | Gmp级规模化制备重组慢病毒载体的纯化制剂的方法 |
| CN110317791A (zh) | 2018-03-29 | 2019-10-11 | 西比曼生物科技（香港）有限公司 | Gmp级无血清悬浮细胞大规模生产慢病毒的方法 |
| GB201806736D0 (en) * | 2018-04-25 | 2018-06-06 | Ge Healthcare Bioprocess R&D Ab | Method for virus purification |
| IL279295B2 (en) | 2018-06-12 | 2026-03-01 | Kentucky Bioprocessing Inc | Purification and cross-linking of virus and antigen |
| US11696948B2 (en) | 2018-06-12 | 2023-07-11 | Kbio Holdings Limited | Vaccines formed by virus and antigen conjugation |
| US11529413B2 (en) | 2018-06-12 | 2022-12-20 | Kbio Holdings Limited | Virus and antigen purification and conjugation |
| EP3581646A1 (en) * | 2018-06-15 | 2019-12-18 | Themis Bioscience GmbH | Integrated manufacturing and chromatographic system for virus production |
| US11999975B2 (en) * | 2018-07-04 | 2024-06-04 | Probiogen Ag | Method for purifying an enveloped virus |
| WO2020214676A1 (en) * | 2019-04-15 | 2020-10-22 | Children's Hospital Medical Center | Viral vector manufacturing methods |
| WO2021041322A1 (en) | 2019-08-23 | 2021-03-04 | Lonza Walkersville, Inc. | Methods and constructs for production of lentiviral vector |
| CN110540956B (zh) * | 2019-08-30 | 2021-07-20 | 博雅干细胞科技有限公司 | 由胎盘间充质干细胞简易制备细胞因子的方法 |
| CN110499287B (zh) * | 2019-08-30 | 2021-07-23 | 博雅干细胞科技有限公司 | 简易制备胎盘间充质干细胞外泌体的方法 |
| BR112022015710A2 (pt) | 2020-02-27 | 2022-09-27 | Takeda Vaccines Inc | Método para remover dna de célula hospedeira a partir da preparação de vírus |
| KR20230024891A (ko) * | 2020-06-11 | 2023-02-21 | 2세븐티 바이오, 인코포레이티드 | 바이러스 벡터 제조 방법 |
| CN111876393A (zh) * | 2020-06-30 | 2020-11-03 | 恒瑞源正（上海）生物科技有限公司 | 一种大规模快速生产高纯度高活性慢病毒载体的方法 |
| CN116590346B (zh) * | 2020-09-15 | 2024-05-14 | 上海药明巨诺生物医药研发有限公司 | 一种慢病毒载体纯化方法 |
| AU2022212090A1 (en) | 2021-01-28 | 2023-07-06 | Allogene Therapeutics, Inc. | Methods for transducing immune cells |
| CN113373120B (zh) * | 2021-06-18 | 2022-04-26 | 浙江康佰裕生物科技有限公司 | Gmp级逆转录病毒载体的纯化方法与应用 |
| US20250137024A1 (en) * | 2021-09-01 | 2025-05-01 | Glaxosmithkline Biologicals Sa | Plasmid dna purification methods |
| CN119256087A (zh) * | 2022-03-14 | 2025-01-03 | 布拉默生物有限责任公司 | 慢病毒制造平台 |
| CN115505578A (zh) * | 2022-09-20 | 2022-12-23 | 苏州博腾生物制药有限公司 | 可放大的用于纯化重组病毒的方法 |
| CN115975955B (zh) * | 2023-01-17 | 2026-03-27 | 珠海市丽珠单抗生物技术有限公司 | 纯化逆转录病毒的试剂盒及纯化方法 |
| CN118813560A (zh) * | 2023-04-20 | 2024-10-22 | 生物岛实验室 | 一种腺病毒制品的纯化方法及其应用 |
| WO2024226858A1 (en) * | 2023-04-26 | 2024-10-31 | Juno Therapeutics, Inc. | Methods for viral vector manufacturing |
| CN118931968B (zh) * | 2024-10-15 | 2025-01-24 | 成都蓉生药业有限责任公司 | 一种BaEV包膜假型慢病毒的纯化方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1358909A (fr) | 1962-06-13 | 1964-04-17 | Autelca Ag | Installation téléphonique d'abonnés avec postes d'abonnés équipés avec un accumulateur |
| JPS63153016A (ja) | 1987-11-10 | 1988-06-25 | 株式会社東芝 | 電気炊飯器 |
| WO1989006276A2 (en) | 1988-01-08 | 1989-07-13 | Dpz Deutsches Primatenzentrum Gesellschaft Mbh | Hiv-2-type retroviruses of primates, vaccines, diagnostic and pharmaceutical compositions |
| EP0738319A4 (en) | 1994-01-12 | 2000-03-29 | Genetic Therapy Inc | Purification of retroviral vectors |
| DE60327069D1 (de) | 2002-04-30 | 2009-05-20 | Oncolytics Biotech Inc | Verbesserte reinigungsmethode für viren |
| KR101400379B1 (ko) * | 2004-11-05 | 2014-05-28 | 웰스테트 바이올로직스 코포레이션 | 안정하고 여과 가능한 외피보유 바이러스 조성물 |
| US7875446B2 (en) * | 2006-04-20 | 2011-01-25 | Wyeth Llc | Purification processes for isolating purified vesicular stomatitis virus from cell culture |
| DK2307551T3 (da) * | 2008-06-18 | 2017-03-20 | Oxford Biomedica (Uk) Ltd | Oprensning af retrovirale vektorer |
| TWI469992B (zh) | 2008-08-28 | 2015-01-21 | Baxter Int | 濃縮剪切靈敏生物聚合物的方法 |
| ES2639307T3 (es) | 2011-06-30 | 2017-10-26 | Genethon | Péptidos con propiedades potenciadoras de infección vírica y su uso |
| US20140315294A1 (en) | 2011-11-24 | 2014-10-23 | Genethon | Scalable lentiviral vector production system compatible with industrial pharmaceutical applications |
| FR3010720B1 (fr) | 2013-09-16 | 2017-08-11 | Genethon | Procede de production de virus enveloppes |
| JP6919827B2 (ja) | 2013-12-20 | 2021-08-18 | ディーエスエム ニュートリショナル プロダクツ アーゲーＤＳＭ Ｎｕｔｒｉｔｉｏｎａｌ Ｐｒｏｄｕｃｔｓ ＡＧ | 微生物から油を回収する方法 |
-
2013
- 2013-12-17 FR FR1362835A patent/FR3014901B1/fr active Active
-
2014
- 2014-12-17 US US15/105,880 patent/US10465169B2/en active Active
- 2014-12-17 SG SG11201605805RA patent/SG11201605805RA/en unknown
- 2014-12-17 EP EP14828237.9A patent/EP3083970B2/fr active Active
- 2014-12-17 WO PCT/FR2014/053406 patent/WO2015092287A1/fr not_active Ceased
- 2014-12-17 DK DK14828237.9T patent/DK3083970T4/da active
- 2014-12-17 ES ES14828237T patent/ES2753300T5/es active Active
- 2014-12-17 CN CN201480075550.8A patent/CN105980571A/zh active Pending
- 2014-12-17 JP JP2016540514A patent/JP6553043B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| FR3014901B1 (fr) | 2017-06-09 |
| JP6553043B2 (ja) | 2019-07-31 |
| FR3014901A1 (fr) | 2015-06-19 |
| EP3083970B1 (fr) | 2019-09-04 |
| JP2017503486A (ja) | 2017-02-02 |
| ES2753300T5 (es) | 2024-09-20 |
| EP3083970A1 (fr) | 2016-10-26 |
| EP3083970B2 (fr) | 2024-03-13 |
| US10465169B2 (en) | 2019-11-05 |
| ES2753300T3 (es) | 2020-04-08 |
| WO2015092287A1 (fr) | 2015-06-25 |
| DK3083970T3 (da) | 2019-11-11 |
| CN105980571A (zh) | 2016-09-28 |
| SG11201605805RA (en) | 2016-09-29 |
| US20170002332A1 (en) | 2017-01-05 |
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