DK3092901T3 - Quinolonanaloger og fremgangsmåder relateret dertil - Google Patents

Quinolonanaloger og fremgangsmåder relateret dertil Download PDF

Info

Publication number: DK3092901T3
Authority: DK; Denmark
Prior art keywords: quinolon; analogs; procedures related; procedures; quinolon analogs
Prior art date: 2007-10-05

Application number

DK16171555.2T

Other languages

English (en)

Inventor

Johnny Yasuo Nagasawa

Fabrice Pierre

Mustapha Haddach

Michael Schwaebe

Levan Darjania

Jeffrey P Whitten

Original Assignee

Senhwa Biosciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-05

Filing date

2008-10-03

Publication date

2020-05-18

2008-10-03 Application filed by Senhwa Biosciences Inc filed Critical Senhwa Biosciences Inc

2020-05-18 Application granted granted Critical

2020-05-18 Publication of DK3092901T3 publication Critical patent/DK3092901T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/16—Peri-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Epidemiology (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

DK16171555.2T 2007-10-05 2008-10-03 Quinolonanaloger og fremgangsmåder relateret dertil DK3092901T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US97804207P	2007-10-05	2007-10-05
US3868108P	2008-03-21	2008-03-21
US4593308P	2008-04-17	2008-04-17
EP08835342.0A EP2214491B1 (en)	2007-10-05	2008-10-03	Quinolone analogs and methods related thereto

Publications (1)

Publication Number	Publication Date
DK3092901T3 true DK3092901T3 (da)	2020-05-18

Family

ID=40523786

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK16171555.2T DK3092901T3 (da)	2007-10-05	2008-10-03	Quinolonanaloger og fremgangsmåder relateret dertil

Country Status (18)

Country	Link
US (2)	US7928100B2 (da)
EP (2)	EP2214491B1 (da)
JP (2)	JP5824213B2 (da)
KR (2)	KR101601332B1 (da)
CN (1)	CN101888780B (da)
AU (1)	AU2008308485B2 (da)
BR (1)	BRPI0817806A2 (da)
CA (1)	CA2701630C (da)
DK (1)	DK3092901T3 (da)
ES (2)	ES2791305T3 (da)
IL (2)	IL204844A (da)
MX (1)	MX2010003685A (da)
NO (1)	NO20100596L (da)
NZ (1)	NZ584892A (da)
PL (2)	PL2214491T3 (da)
PT (2)	PT3092901T (da)
RU (1)	RU2549895C2 (da)
WO (1)	WO2009046383A1 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20110065687A1 (en) *	2007-04-17	2011-03-17	Michael Schwaebe	Hydrazide compounds and uses thereof
US7928100B2 (en) *	2007-10-05	2011-04-19	Cylene Pharmaceuticals, Inc.	Quinolone analogs and methods related thereto
HRP20130951T1 (hr)	2009-08-28	2013-11-22	Takeda Pharmaceutical Company Limited	Spojevi heksahidrooksazinopteridina za uporabu kao inhibitori mtor
US8293925B2 (en) *	2009-09-21	2012-10-23	Chemocentryx, Inc.	Pyrrolidinone carboxamide derivatives
US8791107B2 (en)	2011-02-25	2014-07-29	Takeda Pharmaceutical Company Limited	N-substituted oxazinopteridines and oxazinopteridinones
US20140086839A1 (en)	2011-03-17	2014-03-27	Tel Hashomer Medical Research Infrastructure And Services Ltd.	Quinolone analogs for treating autoimmune diseases
GB201206384D0 (en) *	2012-04-11	2012-05-23	Redx Pharma Ltd	Antibacterial drug derivatives
CN104177379B (zh) *	2013-05-22	2016-12-28	中国科学院上海药物研究所	一种喹诺酮类化合物或其立体化学异构体、包含该化合物的药物组合物及其用途
ES2754207T3 (es)	2013-11-28	2020-04-16	Tel Hashomer Medical Res Infrastructure & Services Ltd	Inhibidores de la ARN polimerasa I y usos de los mismos
TR201809990T4 (en) *	2014-05-09	2018-08-27	Pimera Inc	NEW COMPOSITIONS, USES AND METHODS FOR THEIR MAKING.
US9758518B2 (en)	2015-03-04	2017-09-12	Pimera, Inc.	Compositions, uses and methods for making them
JP7017509B2 (ja)	2015-11-20	2022-02-08	センワバイオサイエンシズインコーポレイテッド	がんを治療するための四環式キノロン類似体の併用療法
JP2018537486A (ja) *	2015-12-14	2018-12-20	センワバイオサイエンシズインコーポレイテッド	キノロン類似体及びその塩の結晶形
US9957282B2 (en) *	2015-12-14	2018-05-01	Senhwa Biosciences, Inc.	Crystalline forms of quinolone analogs and their salts
TWI765848B (zh) *	2015-12-14	2022-06-01	生華生物科技股份有限公司	喹諾酮類似物及其鹽的結晶形式
CN109640959B (zh)	2016-04-29	2023-03-17	西奈山伊坎医学院	靶向先天免疫系统以诱导长期耐受性及解决动脉粥样硬化中的巨噬细胞累积
EP3601286A4 (en)	2017-03-28	2020-09-23	Pimera, Inc.	NEW CRYSTALLINE FORMS OF A POL1 INHIBITOR
US11071727B2 (en)	2018-01-26	2021-07-27	Northwestern University	Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors
CN112334133A (zh) *	2018-02-15	2021-02-05	生华生物科技股份有限公司	喹诺酮类似物及其盐、组合物及其使用方法
WO2020051342A1 (en) *	2018-09-06	2020-03-12	Cornell University	Methods for treating metastatic disease using ribosome biogenesis inhibitor cx 5461
EP4013421A4 (en)	2019-08-14	2023-08-23	Senhwa Biosciences, Inc.	TETRACYCLIC COMPOUNDS AND THEIR SALTS, COMPOSITIONS AND METHODS OF USE
CA3151116A1 (en) *	2019-08-14	2021-02-18	Hshiou-Ting Liu	Crystalline forms of quinoline analogs and salts thereof, compositions, and their methods for use
JP2020189888A (ja) *	2020-08-28	2020-11-26	センワバイオサイエンシズインコーポレイテッド	キノロン類似体及びその塩の結晶形
US12274700B1 (en)	2020-10-30	2025-04-15	Accencio LLC	Methods of treating symptoms of coronavirus infection with RNA polymerase inhibitors
CN114573604B (zh) *	2020-12-01	2024-06-18	中国科学院上海药物研究所	一类基于喹诺酮的化合物、其制备方法、包含其的药物组合物及其用途
AU2022239614A1 (en)	2021-03-19	2023-10-12	Icahn School Of Medicine At Mount Sinai	Compounds for regulating trained immunity, and their methods of use
CN114409681A (zh) *	2022-03-18	2022-04-29	信义核新(北京)生物科技有限公司	用于治疗dna损伤修复缺陷肿瘤的喹诺酮类似物及其应用
WO2024222630A1 (zh) *	2023-04-23	2024-10-31	信义核新(北京)生物科技有限公司	喹诺酮衍生物及其在抗肿瘤中的应用
CN118005653B (zh) *	2023-04-23	2024-12-10	信义核新(北京)生物科技有限公司	喹诺酮类似物及其用途
WO2025114459A1 (en) *	2023-11-28	2025-06-05	Genome Therapeutics Ltd	Tetracyclic compounds for use in antibody-drug conjugates for the treatment of cancer
WO2025133338A1 (en) *	2023-12-21	2025-06-26	Genome Therapeutics Ltd	Quinolone derivatves against cancer

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4559157A (en)	1983-04-21	1985-12-17	Creative Products Resource Associates, Ltd.	Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr)	1983-08-30	1985-04-24	Oreal	Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4820508A (en)	1987-06-23	1989-04-11	Neutrogena Corporation	Skin protective composition
US4992478A (en)	1988-04-04	1991-02-12	Warner-Lambert Company	Antiinflammatory skin moisturizing composition and method of preparing same
US4938949A (en)	1988-09-12	1990-07-03	University Of New York	Treatment of damaged bone marrow and dosage units therefor
US5703055A (en)	1989-03-21	1997-12-30	Wisconsin Alumni Research Foundation	Generation of antibodies through lipid mediated DNA delivery
EG20543A (en) *	1992-10-30	1999-07-31	Procter & Gamble	Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones
EP1165508B1 (en)	1999-04-07	2004-06-23	The University of Virginia Patent Foundation	Anticancer calcium channel blockers
JP2005511743A (ja) *	2001-12-13	2005-04-28	ウォックハート・リミテッド	新世代の三重標的化したキラルな広域スペクトラム抗菌性の７位置換ピペリジノ−キノロンカルボン酸誘導体、その調製方法、組成物、および医薬としての使用
US6900224B2 (en)	2002-07-31	2005-05-31	The Procter & Gamble Company	Antimicrobial quinolones, their compositions and uses
WO2005033108A1 (en) *	2003-09-22	2005-04-14	Janssen Pharmaceutica, N.V.	7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
WO2006034113A2 (en) *	2004-09-17	2006-03-30	Cylene Pharmaceuticals, Inc.	Quinolone analogs as cell proliferation inhibitors
US7816524B2 (en) *	2005-08-05	2010-10-19	Cylene Pharmaceuticals, Inc.	Methods of preparing quinolone analogs
JP2009504192A (ja) *	2005-08-19	2009-02-05	サイリーンファーマシューティカルズインコーポレーティッド	ヒトリボソームＤＮＡ（ｒＤＮＡ）およびリボソームＲＮＡ（ｒＲＮＡ）核酸ならびにそれらの使用
AR057555A1 (es) *	2005-10-27	2007-12-05	Merck Frosst Canada Ltd	Un inhibidor de fosfodiesterasa-4 4-oxo-1-(3-sustituido fenil-1,4-dihidro-1,8-naftiridin-3-carboxamida y un procedimiento de preparacion del mismo
US20090291437A1 (en) *	2005-11-02	2009-11-26	O'brien Sean	Methods for targeting quadruplex sequences
EP2023720A4 (en) *	2006-05-17	2009-06-10	Cylene Pharmaceuticals Inc	TETRACYCLIC IMIDAZOLE ANALOG
WO2007146813A2 (en)	2006-06-08	2007-12-21	Cylene Pharmaceuticals, Inc.	Pyridinone analogs as cell proliferation inhibitors
WO2007146831A2 (en) *	2006-06-08	2007-12-21	Cylene Pharmaceuticals, Inc.	Quinolone analogs derivatized with sulfonic acid, sulfonate or sulfonamide
GB0701992D0 (en)	2007-02-02	2007-03-14	7Tm Pharma As	Grehlin Receptor Modulators
US20110065687A1 (en) *	2007-04-17	2011-03-17	Michael Schwaebe	Hydrazide compounds and uses thereof
US7928100B2 (en) *	2007-10-05	2011-04-19	Cylene Pharmaceuticals, Inc.	Quinolone analogs and methods related thereto

2008
- 2008-10-03 US US12/245,619 patent/US7928100B2/en active Active
- 2008-10-03 KR KR1020107009924A patent/KR101601332B1/ko active Active
- 2008-10-03 EP EP08835342.0A patent/EP2214491B1/en active Active
- 2008-10-03 PL PL08835342.0T patent/PL2214491T3/pl unknown
- 2008-10-03 PT PT161715552T patent/PT3092901T/pt unknown
- 2008-10-03 EP EP16171555.2A patent/EP3092901B1/en active Active
- 2008-10-03 AU AU2008308485A patent/AU2008308485B2/en active Active
- 2008-10-03 PT PT88353420T patent/PT2214491T/pt unknown
- 2008-10-03 MX MX2010003685A patent/MX2010003685A/es not_active Application Discontinuation
- 2008-10-03 PL PL16171555T patent/PL3092901T3/pl unknown
- 2008-10-03 RU RU2010117225/04A patent/RU2549895C2/ru not_active Application Discontinuation
- 2008-10-03 BR BRPI0817806-2A2A patent/BRPI0817806A2/pt not_active IP Right Cessation
- 2008-10-03 NZ NZ584892A patent/NZ584892A/en unknown
- 2008-10-03 JP JP2010528194A patent/JP5824213B2/ja active Active
- 2008-10-03 CN CN200880119635.6A patent/CN101888780B/zh active Active
- 2008-10-03 WO PCT/US2008/078859 patent/WO2009046383A1/en not_active Ceased
- 2008-10-03 CA CA2701630A patent/CA2701630C/en active Active
- 2008-10-03 ES ES16171555T patent/ES2791305T3/es active Active
- 2008-10-03 ES ES08835342.0T patent/ES2582662T3/es active Active
- 2008-10-03 DK DK16171555.2T patent/DK3092901T3/da active
- 2008-10-03 KR KR1020167002742A patent/KR101682867B1/ko active Active
2010
- 2010-04-06 IL IL204844A patent/IL204844A/en active IP Right Grant
- 2010-04-26 NO NO20100596A patent/NO20100596L/no not_active Application Discontinuation
2011
- 2011-03-09 US US13/043,956 patent/US8853234B2/en active Active
2014
- 2014-05-14 JP JP2014100136A patent/JP2014159474A/ja not_active Withdrawn
2017
- 2017-01-02 IL IL249906A patent/IL249906B/en active IP Right Grant

Also Published As

Publication number	Publication date
PL3092901T3 (pl)	2020-10-19
AU2008308485B2 (en)	2014-08-07
CA2701630A1 (en)	2009-04-09
KR101601332B1 (ko)	2016-03-08
KR20100064392A (ko)	2010-06-14
EP3092901A1 (en)	2016-11-16
EP2214491B1 (en)	2016-07-13
WO2009046383A1 (en)	2009-04-09
EP3092901B1 (en)	2020-04-29
KR101682867B1 (ko)	2016-12-05
US20110218184A1 (en)	2011-09-08
ES2791305T3 (es)	2020-11-03
RU2010117225A (ru)	2011-11-10
IL204844A (en)	2017-01-31
EP2214491A1 (en)	2010-08-11
CN101888780A (zh)	2010-11-17
AU2008308485A1 (en)	2009-04-09
PT3092901T (pt)	2020-05-21
HK1150728A1 (en)	2012-01-13
JP5824213B2 (ja)	2015-11-25
KR20160020578A (ko)	2016-02-23
IL204844A0 (en)	2010-11-30
PL2214491T3 (pl)	2016-11-30
JP2014159474A (ja)	2014-09-04
US8853234B2 (en)	2014-10-07
IL249906B (en)	2020-10-29
US7928100B2 (en)	2011-04-19
CA2701630C (en)	2016-10-25
NO20100596L (no)	2010-06-10
US20090093455A1 (en)	2009-04-09
ES2582662T3 (es)	2016-09-14
CN101888780B (zh)	2014-08-13
NZ584892A (en)	2012-06-29
MX2010003685A (es)	2010-06-02
EP2214491A4 (en)	2010-11-10
IL249906A0 (en)	2017-03-30
RU2549895C2 (ru)	2015-05-10
BRPI0817806A2 (pt)	2014-10-07
JP2010540663A (ja)	2010-12-24
PT2214491T (pt)	2016-10-25

Publication	Publication Date	Title
DK3092901T3 (da)	2020-05-18	Quinolonanaloger og fremgangsmåder relateret dertil
BRPI0813647A2 (pt)	2014-12-23	Piperazinil oxoalquil tetrahidro-beta-carbolinas e análogos relacionados
EP2131749A4 (en)	2014-04-02	Surgical stapling apparatus
DK2222675T3 (da)	2013-11-04	5-anilinoimidazopyridiner og fremgangsmåder til deres anvendelse
DE602008006310D1 (de)	2011-06-01	Endoskopischer Reprozessor
DK2185164T3 (da)	2017-11-13	Sammensætning og terapeutisk antitumorvaccine
DK2170827T3 (da)	2013-11-18	Indolin-2-oner og aza-indolin-2-oner
LU92600I2 (fr)	2015-11-24	Sovaldi (sofosbuvir)
DK3338790T3 (da)	2022-05-09	Oligopeptid-forbindelser og anvendelser deraf
DK2185552T3 (da)	2014-06-10	Dipeptoid-prodrugs og anvendelse heraf
BRPI0813546A2 (pt)	2017-05-23	interface ortopédica
DK2146786T3 (da)	2013-04-15	Målanordning
BRPI0821573A2 (pt)	2016-08-09	benzofuropirimidonas
ATE501136T1 (de)	2011-03-15	Imidazopyridinone
DE102007041169B8 (de)	2014-09-04	Flugkorbball
BRPI0814876A2 (pt)	2014-09-30	Análogos de pirona fosforilados e métodos
DK2001556T3 (da)	2014-11-10	Thioninium-forbindelser og anvendelse deraf
DK2805746T3 (da)	2020-08-10	Alkylamido-forbindelser og anvendelser deraf
DK2160336T3 (da)	2013-07-22	Forbindelsesmekanisme og fremgangsmåde
EP2233177A4 (en)	2012-02-08	DEVICE FOR ASSISTING THE EXERCISE
DK2086213T3 (da)	2010-10-18	Billedlæseapparat og billeddannelseapparat
BRPI0812231A2 (pt)	2015-06-23	Dispositivo cirúrgico
DE602008004695D1 (de)	2011-03-10	Katalysatorträgerwabe
DK1999403T3 (da)	2014-06-16	Multikoblingssystem og fremgangsmåde relateret dertil
BRPI0818598A2 (pt)	2017-05-16	agentes terapêuticos - 802