DK310084A - Fremgangsmaade til fremstilling af praevitamin d - Google Patents

Fremgangsmaade til fremstilling af praevitamin d Download PDF

Info

Publication number: DK310084A
Authority: DK; Denmark
Prior art keywords: previtamin; tachysterol; procedure; preparation; photosensitizers
Prior art date: 1983-07-01

Application number

DK310084A

Other languages

English (en)

Other versions

DK310084D0 (da

Inventor

Hans-Juergen Hansen

Karlheinz Pfoertner

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-07-01

Filing date

1984-06-25

Publication date

1985-01-02

1984-06-25 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1984-06-25 Publication of DK310084D0 publication Critical patent/DK310084D0/da

1985-01-02 Publication of DK310084A publication Critical patent/DK310084A/da

Links

XQFJZHAVTPYDIQ-LETJEVNCSA-N (1s)-3-[(e)-2-[(1r,3ar,7ar)-1-[(e,2r,5r)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-1,2,3,3a,6,7-hexahydroinden-4-yl]ethenyl]-4-methylcyclohex-3-en-1-ol Chemical compound C=1([C@@H]2CC[C@@H]([C@]2(CCC=1)C)[C@H](C)/C=C/[C@H](C)C(C)C)\C=C\C1=C(C)CC[C@H](O)C1 XQFJZHAVTPYDIQ-LETJEVNCSA-N 0.000 abstract 3
BUNBVCKYYMRTNS-UHFFFAOYSA-N tachysterol Natural products C=1CCC2(C)C(C(C)CCC(C)C(C)C)CCC2C=1C=CC1=C(C)CCC(O)C1 BUNBVCKYYMRTNS-UHFFFAOYSA-N 0.000 abstract 3
239000003504 photosensitizing agent Chemical group 0.000 abstract 2
YUGCAAVRZWBXEQ-WHTXLNIXSA-N previtamin D3 Chemical compound C=1([C@@H]2CC[C@@H]([C@]2(CCC=1)C)[C@H](C)CCCC(C)C)\C=C/C1=C(C)CC[C@H](O)C1 YUGCAAVRZWBXEQ-WHTXLNIXSA-N 0.000 abstract 2
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical group [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
229910052783 alkali metal Inorganic materials 0.000 abstract 1
-1 alkali metal cation Chemical class 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
239000000460 chlorine Chemical group 0.000 abstract 1
229910052801 chlorine Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052711 selenium Inorganic materials 0.000 abstract 1
239000011669 selenium Chemical group 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Chemical group 0.000 abstract 1
238000009281 ultraviolet germicidal irradiation Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D345/00—Heterocyclic compounds containing rings having selenium or tellurium atoms as the only ring hetero atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Physical Or Chemical Processes And Apparatus (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Application Of Or Painting With Fluid Materials (AREA)
Vending Machines For Individual Products (AREA)

DK310084A 1983-07-01 1984-06-25 Fremgangsmaade til fremstilling af praevitamin d DK310084A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH363783		1983-07-01

Publications (2)

Publication Number	Publication Date
DK310084D0 DK310084D0 (da)	1984-06-25
DK310084A true DK310084A (da)	1985-01-02

Family

ID=4260262

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK310084A DK310084A (da)	1983-07-01	1984-06-25	Fremgangsmaade til fremstilling af praevitamin d

Country Status (6)

Country	Link
US (2)	US4551214A (da)
EP (1)	EP0130509B1 (da)
JP (2)	JPS6025965A (da)
AT (1)	ATE22074T1 (da)
DE (1)	DE3460694D1 (da)
DK (1)	DK310084A (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK353487A (da) *	1986-07-09	1988-01-10	Solarchem Res	Polymere fotokatalysatorer
ES2055019T3 (es) *	1988-12-12	1994-08-16	Duphar Int Res	Metodo para la conversion fotoquimica de compuestos de taquisterol en compuestos de previtamina d y de compuestos de trans-vitamina d en compuestos de cis-vitamina d.
US5175217A (en) *	1988-12-12	1992-12-29	Duphar International Research B.V.	Method for the photochemical conversion of tachysterol compounds into previtamin D compounds and of trans-vitamin D compounds into cis-vitamin D compounds using a polymeric photoinitiator
EP0454204B1 (en) *	1990-04-27	1995-06-28	Duphar International Research B.V	Method for the photochemical isomeration of organic compounds under the influence of a photosensitizer
US5543016A (en) *	1991-07-12	1996-08-06	Inrad	Photoconversion of steroids in microreactors
US20030220308A1 (en) *	2002-05-22	2003-11-27	Holick Michael F.	Compositions for providing vitamin D year round and uses thereof
US20040186082A1 (en) *	2003-03-20	2004-09-23	Hartman Raymond A.	Enhanced phototherapy for the treatment of cancer and autoimmune disease
CN100413604C (zh) *	2005-09-29	2008-08-27	河北衡丰发电有限责任公司	电厂粉煤灰的输送方法
US20070261933A1 (en) *	2006-04-26	2007-11-15	Scott C W	Conveyor roller assembly and conveyor roller insert
CN101830840B (zh) *	2010-05-17	2013-05-08	郭玉	一种维生素d3的生产方法
JP6116842B2 (ja) *	2012-09-25	2017-04-19	国立大学法人東京大学	標的細胞特異的な光増感用化合物。
US12358871B2 (en) *	2019-05-15	2025-07-15	Fermenta Biotech Limited	Photochemical synthesis of vitamin D3 using sensitizers
US20250296950A1 (en) *	2021-09-08	2025-09-25	Hunan Kyf Pharmaceutical. Co., Ltd.	Intermediate compound and preparation method therefor and application thereof
CN114380726B (zh) *	2021-12-31	2024-04-23	浙江花园生物医药股份有限公司	一种维生素d3粗品分离提纯的母液回收制备维生素d3的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US1532790A (en) *	1924-02-01	1925-04-07	Farbenfab Vorm Bayer F & Co	Pyrone dye
US2157351A (en) *	1934-12-28	1939-05-09	Agfa Ansco Corp	Sensitizing dyes for photographic emulsions
CH363342A (de) *	1955-06-14	1962-07-31	Philips Nv	Verfahren zur Herstellung von Tachysterol oder andern Verbindungen mit Tachysterolstruktur
US3575831A (en) *	1967-05-31	1971-04-20	Hoffmann La Roche	Process for the production of vitamin d
US3539590A (en) *	1968-05-20	1970-11-10	Monsanto Co	Substituted 3,3,6,6 - tetramethyl-1,8 - diketo - 9 - (2 - hydroxyphenyl) octahydroxanthenes
GB1592170A (en) *	1977-01-07	1981-07-01	Hoffmann La Roche	1a-hydroxycholecalciferol-25-hydroxy esters and their use in radioimmunoassay
DE3048698A1 (de) *	1980-12-23	1982-07-15	Wisconsin Alumni Research Foundation, 53707 Madison, Wis.	Verfahren zur herstellung einer 1(alpha)-hydroxylierten vitamin-d-verbindung, ausgehend von einer 5,6-trans-vitamin-d-verbindung
US4338250A (en) *	1981-04-27	1982-07-06	Wisconsin Alumni Research Foundation	1-Hydroxylation process

1984
- 1984-06-14 US US06/620,418 patent/US4551214A/en not_active Expired - Lifetime
- 1984-06-23 EP EP84107214A patent/EP0130509B1/de not_active Expired
- 1984-06-23 DE DE8484107214T patent/DE3460694D1/de not_active Expired
- 1984-06-23 AT AT84107214T patent/ATE22074T1/de active
- 1984-06-25 DK DK310084A patent/DK310084A/da not_active Application Discontinuation
- 1984-06-30 JP JP59134140A patent/JPS6025965A/ja active Granted
1985
- 1985-06-26 US US06/749,072 patent/US4582641A/en not_active Expired - Lifetime
1991
- 1991-12-10 JP JP3349803A patent/JPH0791287B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE3460694D1 (en)	1986-10-16
DK310084D0 (da)	1984-06-25
JPH0434990B2 (da)	1992-06-09
JPS6025965A (ja)	1985-02-08
EP0130509B1 (de)	1986-09-10
JPH06293752A (ja)	1994-10-21
EP0130509A1 (de)	1985-01-09
ATE22074T1 (de)	1986-09-15
US4582641A (en)	1986-04-15
JPH0791287B2 (ja)	1995-10-04
US4551214A (en)	1985-11-05

Legal Events

Date	Code	Title	Description
1987-09-28	AHB	Application shelved due to non-payment
2000-01-24	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK310084D0 (da)	1984-06-25	Fremgangsmaade til fremstilling af praevitamin d
DE3373308D1 (en)	1987-10-08	Process for the preparation of sulphur-containing organosilicon compounds
FR2477128B1 (da)	1982-06-18
ATE77401T1 (de)	1992-07-15	Thixotrope zubereitungen, verwendung von polycarbonsaeureamiden zu ihrer herstellung und mit polycarbonsaeureamiden beschichtetes siliciumdioxid.
DK0822920T3 (da)	2002-01-21	Fremgangsmåde til fremstilling af en chlordioxidholdig desinfektionsopløsning til vandrensning
ES8603372A1 (es)	1985-12-16	Un procedimiento para la preparacion de oxo-analogos de compuestos del tipo de la mevinolina.
ES551531A0 (es)	1987-01-01	Procedimiento para detectar peroxido de hidrogeno o sustancias formadoras de peroxido de hidrogeno
PH15281A (en)	1982-11-02	Pyrimido(6,1-a)isoquinolin-4-ones
DE3560902D1 (en)	1987-12-10	Vitamin d3 derivatives
DE3664909D1 (en)	1989-09-14	Vitamin d3 derivatives
GB2020300A (en)	1979-11-14	Polyarylether sulphone mixtures
GB1459379A (en)	1976-12-22	Process for producing a-type calcium sulphate hemihydrate
AU534773B2 (en)	1984-02-16	Gh-1,2,4,6-thiatriazine 1,1-dioxides herbicides
NO169176C (no)	1992-05-20	Tyroninderivater, og deres fremstillig og anvendelse
NO167085C (no)	1991-10-02	Fremgangsmaate for fremstilling av (1-fenylethyl)-hydrokinon.
JPS5518259A (en)	1980-02-08	Available chlorine activity maintainer in water
ATE17228T1 (de)	1986-01-15	Verfahren zur oxydation von vinylbenzenverbindungen zu beta-phenylaldehyden.
GR82125B (da)	1984-12-13
KR840001957A (ko)	1984-06-07	신규의 이소프로필 아미노 피리미딘 유도체의 제조방법
JPS5299966A (en)	1977-08-22	Treatment for removing halogen gas
JPS5711818A (en)	1982-01-21	Novel crystalline silicate and its preparation
GB1525372A (en)	1978-09-20	4-deacetoxyvincristine
GB1060263A (en)	1967-03-01	Benzenesulphonyl isourea ethers and a process for their manufacture
JPS57149816A (en)	1982-09-16	Manufacture of sodium silicofluoride from waste gas containing fluorine
ES8400424A1 (es)	1983-11-01	Procedimiento para preparar 5,6-dihidro-2-metil-n-fenil-1,4-oxatiin-3-carboxamida.