DK3129779T3 - Fremgangsmåder og sammensætninger til påvisning af fejlfoldede proteiner - Google Patents
Fremgangsmåder og sammensætninger til påvisning af fejlfoldede proteiner Download PDFInfo
- Publication number
- DK3129779T3 DK3129779T3 DK15776737.7T DK15776737T DK3129779T3 DK 3129779 T3 DK3129779 T3 DK 3129779T3 DK 15776737 T DK15776737 T DK 15776737T DK 3129779 T3 DK3129779 T3 DK 3129779T3
- Authority
- DK
- Denmark
- Prior art keywords
- proteins
- procedures
- compositions
- professional
- detecting
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6827—Total protein determination, e.g. albumin in urine
- G01N33/6839—Total protein determination, e.g. albumin in urine involving dyes, e.g. Coomassie blue, bromcresol green
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B69/00—Dyes not provided for by a single group of this subclass
- C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
- C09B69/106—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing an azo dye
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461978158P | 2014-04-10 | 2014-04-10 | |
| PCT/US2015/025432 WO2015157704A2 (en) | 2014-04-10 | 2015-04-10 | Methods and compositions for detecting misfolded proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3129779T3 true DK3129779T3 (da) | 2020-09-07 |
Family
ID=54264908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15776737.7T DK3129779T3 (da) | 2014-04-10 | 2015-04-10 | Fremgangsmåder og sammensætninger til påvisning af fejlfoldede proteiner |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10324094B2 (da) |
| EP (2) | EP3745127B1 (da) |
| JP (1) | JP6697394B2 (da) |
| CN (2) | CN106461644B (da) |
| AU (3) | AU2015243171B2 (da) |
| CA (2) | CA2945058C (da) |
| DK (1) | DK3129779T3 (da) |
| ES (1) | ES2817417T3 (da) |
| MX (2) | MX383381B (da) |
| WO (1) | WO2015157704A2 (da) |
| ZA (1) | ZA201606987B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105021821B (zh) | 2008-10-31 | 2018-05-11 | 耶鲁大学 | 先兆子痫检测和治疗的方法和组合物 |
| ES2817417T3 (es) | 2014-04-10 | 2021-04-07 | Univ Yale | Métodos y composiciones para la detección de proteínas mal plegadas |
| TWI800009B (zh) * | 2015-07-15 | 2023-04-21 | 美商蓋斯特維炫股份有限公司 | 用於檢測折疊錯誤蛋白質之裝置及其使用方法 |
| WO2017180984A1 (en) * | 2016-04-14 | 2017-10-19 | The Texas A&M University System | First trimester epigenetic and microrna biomarkers for preeclampsia |
| US10345244B2 (en) * | 2016-06-03 | 2019-07-09 | International Business Machines Corporation | Diagnostic test device with patterned material spots |
| US10335045B2 (en) | 2016-06-24 | 2019-07-02 | Universita Degli Studi Di Trento | Self-adaptive matrix completion for heart rate estimation from face videos under realistic conditions |
| US10269107B2 (en) * | 2017-02-23 | 2019-04-23 | Global Neighbor Inc | Selective plant detection and treatment using green luminance photometric machine vision scan with real time chromaticity operations and image parameter floors for low processing load |
| WO2019071240A1 (en) | 2017-10-06 | 2019-04-11 | The Research Foundation For The State University For The State Of New York | AQUEOUS AND NONAQUEOUS SELECTIVE OPTICAL DETECTION OF FREE SULPHITES |
| WO2019128506A1 (zh) * | 2017-12-28 | 2019-07-04 | 浙江数问生物技术有限公司 | 一种检测错误折叠蛋白质的装置、试剂盒和方法 |
| US11255844B2 (en) * | 2018-03-06 | 2022-02-22 | Fresenius Medical Care Holdings, Inc. | Peritoneal dialysis systems and related methods |
| CN109659011A (zh) * | 2018-12-29 | 2019-04-19 | 杭州脉流科技有限公司 | 利用移动设备采集处理十二导联ecg图像的方法以及移动设备和计算机可读存储介质 |
| EP4241285A4 (en) * | 2020-11-06 | 2024-09-04 | The Board of Trustees of the Leland Stanford Junior University | SYSTEMS AND METHODS FOR ASSESSING GESTATIONAL PROGRESS AND APPLICATIONS THEREOF |
| CA3199642A1 (en) * | 2020-11-21 | 2022-05-27 | Shuwen Biotech Co. Ltd. | Apparatus and method for detecting misfolded protein in biological sample |
| WO2022235564A1 (en) * | 2021-05-03 | 2022-11-10 | Memorial Sloan Kettering Cancer Center | Detection of labels in biomedical images |
| TW202409564A (zh) * | 2022-05-20 | 2024-03-01 | 大陸商數問生物技術（宣城）有限公司 | 用於檢測生物樣本中的錯誤折疊蛋白質的裝置和方法 |
| WO2024249849A2 (en) * | 2023-05-31 | 2024-12-05 | Northwestern University | Scalable platform for single cell proteomics via digitized detection of proteins and their proteoforms |
| CN117236201B (zh) * | 2023-11-16 | 2024-02-23 | 南京信息工程大学 | 一种基于Diffusion和ViT的降尺度方法 |
| CN120761295B (zh) * | 2025-08-21 | 2026-02-13 | 赛克赛斯生物科技股份有限公司 | 三苯甲烷类化合物在检测阿尔茨海默症中的应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US234610A (en) * | 1880-11-16 | Robert o | ||
| US4444879A (en) | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
| WO1992017769A1 (en) * | 1991-03-28 | 1992-10-15 | Micro Research Inc. | Controlled-release solid phase assay device including encapsulated reagents for detecting chemical substances |
| US5998216A (en) | 1996-10-01 | 1999-12-07 | Beth Israel Deaconess Medical Center | Stabilizing formulation for preserving the integrity of proteins present in a body fluid sampled ex-vivo for evaluation as a specimen |
| AU5331298A (en) | 1996-12-23 | 1998-07-17 | Cambridge University Technical Services Limited | Diagnosis and treatment of pathological pregnancies |
| US6444435B1 (en) * | 2000-11-30 | 2002-09-03 | Serim Research Corporation | Test strip for determining dialysate composition |
| US7355044B2 (en) | 2001-10-25 | 2008-04-08 | Agfa-Gevaert N.V. | Self-assembling dyes |
| BRPI0312818B8 (pt) | 2002-07-19 | 2021-05-25 | Beth Israel Deaconess Medical Ct Inc | uso de uma medida do nível do polipeptídeo sflt-1 em uma amostra de uma paciente e uso de uma medida dos níveis de pelo menos dois dos peptídeos sflt1, vegf livre ou polipeptídio pigf livre em uma amostra de um paciente usando um métrico |
| ATE506072T1 (de) | 2002-09-12 | 2011-05-15 | Univ California | Immunogene und entsprechende antikörper, die spezifisch sind für häufige hochmolekulare aggregations-zwischenprodukte von amyloiden aus proteinen unterschiedlicher sequenz |
| BRPI0519096A2 (pt) | 2004-12-15 | 2008-12-23 | Beth Israel Hospital | Ácidos nuclÉicos e polipeptÍdeos éteis para o diagnàstico e tratamento de complicaÇÕes na gravidez |
| ATE519109T1 (de) | 2004-12-21 | 2011-08-15 | Univ Yale | Präeklampsie-diagnose |
| EP1733762A1 (en) | 2005-05-25 | 2006-12-20 | 3M Espe AG | Dental composition for detection of carious tissue, detection method |
| WO2007051069A2 (en) | 2005-10-27 | 2007-05-03 | Yale University | Urinary proteomic biomarker patterns in preeclampsia |
| KR20100098606A (ko) * | 2007-10-18 | 2010-09-08 | 몸텍 라이프 리미티드 | 임신중에 양막 파열을 확인하는 진단기 |
| US20110065139A1 (en) * | 2007-11-27 | 2011-03-17 | Jacob Mullerad | diagnostic device for identifying rupture of membrane during pregnancy |
| CN105021821B (zh) | 2008-10-31 | 2018-05-11 | 耶鲁大学 | 先兆子痫检测和治疗的方法和组合物 |
| CN103012599B (zh) | 2012-11-28 | 2015-04-29 | 龙岩九健生物芯片技术研究所 | 一种调节硝酸纤维素硝化取代度的方法 |
| ES2817417T3 (es) | 2014-04-10 | 2021-04-07 | Univ Yale | Métodos y composiciones para la detección de proteínas mal plegadas |
-
2015
- 2015-04-10 ES ES15776737T patent/ES2817417T3/es active Active
- 2015-04-10 US US14/683,908 patent/US10324094B2/en active Active
- 2015-04-10 JP JP2016561743A patent/JP6697394B2/ja active Active
- 2015-04-10 EP EP20168843.9A patent/EP3745127B1/en active Active
- 2015-04-10 CA CA2945058A patent/CA2945058C/en active Active
- 2015-04-10 AU AU2015243171A patent/AU2015243171B2/en active Active
- 2015-04-10 CN CN201580031385.0A patent/CN106461644B/zh active Active
- 2015-04-10 WO PCT/US2015/025432 patent/WO2015157704A2/en not_active Ceased
- 2015-04-10 EP EP15776737.7A patent/EP3129779B1/en active Active
- 2015-04-10 CA CA3157573A patent/CA3157573C/en active Active
- 2015-04-10 DK DK15776737.7T patent/DK3129779T3/da active
- 2015-04-10 CN CN202210738173.8A patent/CN116027043A/zh active Pending
- 2015-04-10 MX MX2016013255A patent/MX383381B/es unknown
-
2016
- 2016-10-07 MX MX2021006791A patent/MX2021006791A/es unknown
- 2016-10-11 ZA ZA2016/06987A patent/ZA201606987B/en unknown
-
2019
- 2019-05-08 US US16/406,942 patent/US11079392B2/en active Active
-
2020
- 2020-10-02 AU AU2020244572A patent/AU2020244572B2/en active Active
-
2021
- 2021-06-29 US US17/361,967 patent/US11953505B2/en active Active
-
2022
- 2022-12-23 AU AU2022291625A patent/AU2022291625B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017518483A (ja) | 2017-07-06 |
| US11953505B2 (en) | 2024-04-09 |
| US10324094B2 (en) | 2019-06-18 |
| EP3745127A1 (en) | 2020-12-02 |
| EP3129779A2 (en) | 2017-02-15 |
| ES2817417T3 (es) | 2021-04-07 |
| WO2015157704A3 (en) | 2016-04-28 |
| CA2945058A1 (en) | 2015-10-15 |
| AU2020244572B2 (en) | 2022-12-15 |
| MX2016013255A (es) | 2017-05-03 |
| US20220043001A1 (en) | 2022-02-10 |
| CN106461644B (zh) | 2022-05-13 |
| CN116027043A (zh) | 2023-04-28 |
| EP3129779B1 (en) | 2020-06-03 |
| AU2020244572A1 (en) | 2020-11-05 |
| AU2015243171B2 (en) | 2020-10-15 |
| CN106461644A (zh) | 2017-02-22 |
| CA3157573C (en) | 2025-11-18 |
| AU2022291625B2 (en) | 2024-09-12 |
| EP3745127B1 (en) | 2024-08-28 |
| WO2015157704A2 (en) | 2015-10-15 |
| MX383381B (es) | 2025-03-13 |
| CA2945058C (en) | 2022-07-12 |
| MX2021006791A (es) | 2021-07-15 |
| ZA201606987B (en) | 2020-01-29 |
| CA3157573A1 (en) | 2015-10-15 |
| AU2015243171A1 (en) | 2016-10-27 |
| US20190353662A1 (en) | 2019-11-21 |
| JP6697394B2 (ja) | 2020-05-20 |
| AU2022291625A1 (en) | 2023-02-16 |
| US11079392B2 (en) | 2021-08-03 |
| US20150293115A1 (en) | 2015-10-15 |
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