ATE519109T1 - Präeklampsie-diagnose - Google Patents
Präeklampsie-diagnoseInfo
- Publication number
- ATE519109T1 ATE519109T1 AT05857213T AT05857213T ATE519109T1 AT E519109 T1 ATE519109 T1 AT E519109T1 AT 05857213 T AT05857213 T AT 05857213T AT 05857213 T AT05857213 T AT 05857213T AT E519109 T1 ATE519109 T1 AT E519109T1
- Authority
- AT
- Austria
- Prior art keywords
- pregnancy
- preeclampsia
- risk
- levels
- present
- Prior art date
Links
- 201000011461 pre-eclampsia Diseases 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 title 1
- 230000035935 pregnancy Effects 0.000 abstract 2
- 206010061452 Complication of pregnancy Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 108010082093 Placenta Growth Factor Proteins 0.000 abstract 1
- 102100035194 Placenta growth factor Human genes 0.000 abstract 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 abstract 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 abstract 1
- 239000002870 angiogenesis inducing agent Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/321—Arterial hypertension
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63794804P | 2004-12-21 | 2004-12-21 | |
| PCT/US2005/047010 WO2006069373A2 (en) | 2004-12-21 | 2005-12-21 | Diagnosis of preeclampsia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE519109T1 true ATE519109T1 (de) | 2011-08-15 |
Family
ID=36602368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05857213T ATE519109T1 (de) | 2004-12-21 | 2005-12-21 | Präeklampsie-diagnose |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7727733B2 (de) |
| EP (2) | EP1839056B1 (de) |
| JP (1) | JP5009811B2 (de) |
| CN (1) | CN101163970A (de) |
| AT (1) | ATE519109T1 (de) |
| ES (2) | ES2475975T3 (de) |
| WO (1) | WO2006069373A2 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101215701B1 (ko) | 2002-07-19 | 2012-12-26 | 베스 이스라엘 데코니스 메디칼 센터 | 자간전증 또는 자간의 진단 및 치료 방법 |
| US7335362B2 (en) | 2002-07-19 | 2008-02-26 | Beth Israel Deaconess Medical Center | Methods of treating pre-eclampsia or eclampsia |
| US7435419B2 (en) | 2002-07-19 | 2008-10-14 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating pre-eclampsia or eclampsia |
| US8273383B2 (en) | 2004-05-04 | 2012-09-25 | Children's Medical Center Corporation | Methods and compositions for treatment of preeclampsia |
| EP2347765B1 (de) | 2004-09-24 | 2014-01-22 | Beth Israel Deaconess Medical Center | Verfahren zur Diagnose und Behandlung von Schwangerschaftskomplikationen |
| US7740849B2 (en) | 2004-09-24 | 2010-06-22 | Beth Israel Deaconess Medical Center | Use of compounds that bind soluble endoglin and SFLT-1 for the treatment of pregnancy related hypertensive disorders |
| DE602005023216D1 (de) | 2004-12-15 | 2010-10-07 | Beth Israel Hospital | Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen |
| EP1839056B1 (de) * | 2004-12-21 | 2011-08-03 | Yale University | Präeklampsie-diagnose |
| US20060257901A1 (en) * | 2005-03-24 | 2006-11-16 | Beth Israel Deaconess Medical Center | Methods of diagnosing fetal trisomy 13 or a risk of fetal trisomy 13 during pregnancy |
| EP1946121A2 (de) | 2005-10-27 | 2008-07-23 | Yale University, Inc. | Proteomische harn-biomarkermuster bei präeklampsie |
| US20070111326A1 (en) * | 2005-11-14 | 2007-05-17 | Abbott Laboratories | Diagnostic method for proteinaceous binding pairs, cardiovascular conditions and preeclampsia |
| US20090286271A1 (en) * | 2006-05-31 | 2009-11-19 | Karumanchi Ananth S | Methods of Diagnosing and Treating Complications of Pregnancy |
| US20080071151A1 (en) * | 2006-06-30 | 2008-03-20 | Sogin David C | Method and Apparatus for Diagnosing Pre-eclampsia |
| ATE476665T1 (de) * | 2006-09-20 | 2010-08-15 | Hoffmann La Roche | Natriurethische peptide und plazenta- wachstumfaktor/löslicher vegf-rezeptor unterscheiden zwischen mit der plazenta verbundener herzdysfunktion und mit herzerkrankung verbundener herzdysfunktion |
| JP2010512781A (ja) | 2006-12-20 | 2010-04-30 | イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム リミテッド | Vegfrの変化体ならびに妊娠関連の医学的状態の診断および処置におけるその使用 |
| CN101259119B (zh) * | 2007-03-08 | 2010-05-19 | 上海市计划生育科学研究所 | 一种丝氨酸蛋白酶抑制剂及其衍生物在生育调节中的应用 |
| RU2523887C2 (ru) | 2008-01-07 | 2014-07-27 | Орто-Клиникал Дайэгностикс, Инк. | Калибратор/регулятор для синхронного анализа белков, способных к комплексообразованию друг с другом |
| CA2711071A1 (en) | 2008-01-07 | 2009-07-16 | Ortho-Clinical Diagnostics, Inc. | Determination of sflt-1:angiogenic factor complex |
| WO2009094665A1 (en) * | 2008-01-25 | 2009-07-30 | Perkinelmer Health Sciences, Inc. | Methods for determining the risk of prenatal complications |
| WO2009108073A1 (en) * | 2008-02-28 | 2009-09-03 | Auckland Uniservices Limited | Biomarkers for prediction of preeclampsia and/or cardiovascular disease |
| CN107677828A (zh) * | 2008-10-31 | 2018-02-09 | 耶鲁大学 | 子痫前期检测和治疗的方法和组合物 |
| BRPI0920897A2 (pt) * | 2008-11-24 | 2015-12-29 | Corthera Inc | prognóstico e prevenção de pré-eclampsia |
| WO2010091253A1 (en) | 2009-02-06 | 2010-08-12 | Women & Infants' Hospital Of Rhode Island | Compositions, formulations and methods of treating preeclampsia-type disorders of pregnancy |
| CN101643785B (zh) * | 2009-06-18 | 2011-12-21 | 中国人民解放军第二军医大学 | 用于妊娠高血压综合症检测的hsa-mir-210试剂盒及检测方法 |
| US20130045889A1 (en) * | 2010-04-13 | 2013-02-21 | Pronota N.V. | Biomarkers for hypertensive disorders of pregnancy |
| US20110251094A1 (en) | 2010-04-13 | 2011-10-13 | Pronota N.V. | Biomarkers for hypertensive disorders of pregnancy |
| EP2569253A4 (de) * | 2010-05-14 | 2013-10-02 | Beth Israel Hospital | Extrakorporale vorrichtungen und verfahren zur behandlung von komplikationen während einer schwangerschaft |
| EP2766726A1 (de) | 2011-10-14 | 2014-08-20 | Aarhus Universitet | Diagnostischr und prognostische verwendung von prombp-komplexen |
| US20150087553A1 (en) * | 2012-04-13 | 2015-03-26 | Bioscreening and Diagnostics, LLC | Early trimester screening for early- and late-onset preeclampsia |
| CN104487593A (zh) * | 2012-05-08 | 2015-04-01 | 斯坦福大学托管董事会 | 用于提供先兆子痫评估的方法和组合物 |
| MX356775B (es) | 2012-06-27 | 2018-06-13 | Hoffmann La Roche | Medios y metodos que aplican sflt-1/plgf o relacion de endoglina/plgf para descartar el inicio de preeclampsia en un determinado periodo de tiempo. |
| WO2014037863A1 (en) * | 2012-09-04 | 2014-03-13 | Pluristem Ltd. | Methods for prevention and treatment of preeclampsia |
| RU2519083C1 (ru) * | 2012-10-29 | 2014-06-10 | Федеральное государственное бюджетное учреждение "Уральский научно-исследовательский институт охраны материнства и младенчества" Министерства здравоохранения и социального развития Российской Федерации (ФГБУ "НИИ ОММ" Минздравсоцразвития России) | Способ прогноза гипертензионных осложнений беременности у пациенток с гестационным сахарным диабетом |
| GB201303649D0 (en) | 2013-03-01 | 2013-04-17 | Univ Aston | Hydrogen sulphide compounds |
| CN103207274B (zh) * | 2013-04-28 | 2015-02-25 | 成都中医药大学 | 一种胎儿7号染色体异常疾病的筛查试剂盒 |
| EP3097422B1 (de) | 2014-01-24 | 2018-07-11 | Roche Diagnostics GmbH | Vorhersage von postpartalem hellp-syndrom, postpartaler eklampsie oder postpartaler präeklampsie |
| FR3017955B1 (fr) * | 2014-02-27 | 2018-04-06 | Assistance Publique - Hopitaux De Paris | Biomarqueurs diagnostics de la cardiomyopathie du peripartum |
| AU2015243171B2 (en) | 2014-04-10 | 2020-10-15 | Yale University | Methods and compositions for detecting misfolded proteins |
| EP3175239A1 (de) * | 2014-07-30 | 2017-06-07 | Matthew Cooper | Verfahren und zusammensetzungen zur diagnose, prognose und bestätigung von präeklampsie |
| WO2016132136A1 (en) * | 2015-02-18 | 2016-08-25 | Aston University | Diagnostic assay and treatment for preeclampsia |
| CA2998275A1 (en) * | 2015-09-11 | 2017-03-16 | Universidad De Los Andes | In vitro method for identifying a pregnancy related disease |
| CL2018000664A1 (es) | 2015-09-11 | 2019-02-08 | Univ Los Andes | Método in vitro para identificar una enfermedad relacionada con el embarazo |
| CN107884570A (zh) * | 2016-09-29 | 2018-04-06 | 韦彦余 | 一种孕妇先兆子痫检测试剂盒 |
| WO2018076134A1 (en) * | 2016-10-24 | 2018-05-03 | Ldx Prognostics Limited Co. | Methods and kits for providing a preeclampsia assessment and prognosing preterm birth |
| CN110366597B (zh) * | 2016-12-20 | 2024-03-29 | 善威生物私人有限公司 | 用蛋白酶抑制剂进行血液图谱分析 |
| CA3075688A1 (en) | 2017-09-13 | 2019-03-21 | Progenity, Inc. | Preeclampsia biomarkers and related systems and methods |
| CN109557320A (zh) * | 2018-11-26 | 2019-04-02 | 余波澜 | 辅助检测胎盘植入的试剂盒及其应用 |
| EP4070113A4 (de) | 2019-12-04 | 2023-12-20 | Biora Therapeutics, Inc. | Beurteilung von präeklampsie unter verwendung von tests für freien und dissoziierten plazentalen wachstumsfaktor |
| US12436155B2 (en) | 2020-04-16 | 2025-10-07 | Kalia Health, Inc. | Preeclampsia screening device and methods measuring activin and/or inhibin A |
| US20230298758A1 (en) * | 2020-11-06 | 2023-09-21 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and Methods for Evaluating Gestational Progress and Applications Thereof |
| US20220298364A1 (en) | 2021-03-18 | 2022-09-22 | The Patent Well LLC | Corrosion-Inhibiting Coatings for Metal Mesh Gaskets and Metallic Particles |
| JP7851566B2 (ja) | 2021-12-08 | 2026-04-27 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 早発性子癇前症の予後についてのバイオマーカー |
| CN120380346A (zh) | 2022-12-08 | 2025-07-25 | B.R.A.H.M.S有限公司 | 用于早发型先兆子痫预后的多个sFlt-1测量值 |
| CN116953255A (zh) * | 2023-07-27 | 2023-10-27 | 山东大学 | 血清中总IgM和/或总IgG在子痫前期预测或诊断中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444879A (en) * | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
| US5998216A (en) * | 1996-10-01 | 1999-12-07 | Beth Israel Deaconess Medical Center | Stabilizing formulation for preserving the integrity of proteins present in a body fluid sampled ex-vivo for evaluation as a specimen |
| WO1998028006A1 (en) * | 1996-12-23 | 1998-07-02 | Cambridge University Technical Services Limited | Diagnosis and treatment of pathological pregnancies |
| CA2430889A1 (en) * | 2002-06-19 | 2003-12-19 | Bayer Corporation | Stabilization of brain natriuretic peptide (bnp) in blood samples, methods and compositions related thereto |
| AU2003277808A1 (en) | 2002-06-21 | 2004-01-06 | Exxonmobil Chemical Patents Inc. | Yttrium-based ethylene polymerization catalysts with bulky amidinate ancillary ligands |
| KR101215701B1 (ko) * | 2002-07-19 | 2012-12-26 | 베스 이스라엘 데코니스 메디칼 센터 | 자간전증 또는 자간의 진단 및 치료 방법 |
| DE60200248T2 (de) * | 2002-08-01 | 2005-01-27 | Mtm Laboratories Ag | Verfahren für Lösung-basierte Diagnose |
| EP1962096B1 (de) * | 2002-11-16 | 2012-07-18 | Siemens Healthcare Diagnostics Products GmbH | SCD40L, PAPP-A und plazentaler-Wachstumsfaktor (PIGF) als biochemische Markerkombination bei kardiovaskulären Erkrankungen |
| DE602005023216D1 (de) * | 2004-12-15 | 2010-10-07 | Beth Israel Hospital | Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen |
| EP1839056B1 (de) * | 2004-12-21 | 2011-08-03 | Yale University | Präeklampsie-diagnose |
| EP1946121A2 (de) | 2005-10-27 | 2008-07-23 | Yale University, Inc. | Proteomische harn-biomarkermuster bei präeklampsie |
-
2005
- 2005-12-21 EP EP05857213A patent/EP1839056B1/de not_active Expired - Lifetime
- 2005-12-21 EP EP11176350.4A patent/EP2434283B1/de not_active Expired - Lifetime
- 2005-12-21 AT AT05857213T patent/ATE519109T1/de not_active IP Right Cessation
- 2005-12-21 CN CN200580047028.XA patent/CN101163970A/zh active Pending
- 2005-12-21 ES ES11176350.4T patent/ES2475975T3/es not_active Expired - Lifetime
- 2005-12-21 US US11/314,073 patent/US7727733B2/en active Active
- 2005-12-21 ES ES05857213T patent/ES2371084T3/es not_active Expired - Lifetime
- 2005-12-21 WO PCT/US2005/047010 patent/WO2006069373A2/en not_active Ceased
- 2005-12-21 JP JP2007548575A patent/JP5009811B2/ja not_active Expired - Lifetime
-
2010
- 2010-05-17 US US12/781,474 patent/US7935496B2/en not_active Expired - Lifetime
-
2011
- 2011-03-21 US US13/053,045 patent/US8871448B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20120040371A1 (en) | 2012-02-16 |
| EP2434283B1 (de) | 2014-03-26 |
| JP2008524635A (ja) | 2008-07-10 |
| CN101163970A (zh) | 2008-04-16 |
| WO2006069373A3 (en) | 2006-11-23 |
| ES2475975T3 (es) | 2014-07-11 |
| US20100227342A1 (en) | 2010-09-09 |
| EP1839056A2 (de) | 2007-10-03 |
| US7935496B2 (en) | 2011-05-03 |
| EP2434283A2 (de) | 2012-03-28 |
| JP5009811B2 (ja) | 2012-08-22 |
| WO2006069373A8 (en) | 2006-09-14 |
| EP2434283A3 (de) | 2012-07-11 |
| EP1839056B1 (de) | 2011-08-03 |
| US8871448B2 (en) | 2014-10-28 |
| EP1839056A4 (de) | 2008-05-21 |
| ES2371084T3 (es) | 2011-12-27 |
| US20060183175A1 (en) | 2006-08-17 |
| US7727733B2 (en) | 2010-06-01 |
| WO2006069373A2 (en) | 2006-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |