DK3143403T3 - Fremgangsmåder til påvisning og/eller måling af anti-lægemiddelantistoffer, især behandlingsinducerede anti-lægemiddelantistoffer - Google Patents
Fremgangsmåder til påvisning og/eller måling af anti-lægemiddelantistoffer, især behandlingsinducerede anti-lægemiddelantistoffer Download PDFInfo
- Publication number
- DK3143403T3 DK3143403T3 DK15723216.6T DK15723216T DK3143403T3 DK 3143403 T3 DK3143403 T3 DK 3143403T3 DK 15723216 T DK15723216 T DK 15723216T DK 3143403 T3 DK3143403 T3 DK 3143403T3
- Authority
- DK
- Denmark
- Prior art keywords
- drug antibodies
- inducted
- procedures
- measurement
- detection
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461994472P | 2014-05-16 | 2014-05-16 | |
| PCT/EP2015/060671 WO2015173342A1 (en) | 2014-05-16 | 2015-05-13 | Methods for detecting and/or measuring anti-drug antibodies, in particular treatment-emergent anti-drug antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3143403T3 true DK3143403T3 (da) | 2022-01-17 |
Family
ID=53189050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15723216.6T DK3143403T3 (da) | 2014-05-16 | 2015-05-13 | Fremgangsmåder til påvisning og/eller måling af anti-lægemiddelantistoffer, især behandlingsinducerede anti-lægemiddelantistoffer |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11009511B2 (da) |
| EP (2) | EP3143403B1 (da) |
| AU (2) | AU2015261467B2 (da) |
| CA (1) | CA2948945C (da) |
| CY (1) | CY1125342T1 (da) |
| DK (1) | DK3143403T3 (da) |
| ES (1) | ES2900852T3 (da) |
| HU (1) | HUE056738T2 (da) |
| WO (1) | WO2015173342A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201805064SA (en) | 2011-06-23 | 2018-07-30 | Ablynx Nv | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
| US11009511B2 (en) * | 2014-05-16 | 2021-05-18 | Ablynx N.V. | Methods for detecting and/or measuring anti-drug antibodies, in particular treatment-emergent anti-drug antibodies |
| AU2017281421B2 (en) * | 2016-06-23 | 2024-07-25 | Ablynx N.V. | Improved pharmacokinetic assays for immunoglobulin single variable domains |
| US12480957B2 (en) | 2017-03-31 | 2025-11-25 | Ablynx N.V. | Method of screening for anti-drug antibodies against immunoglobulin single variable domain-based drugs |
| WO2021136773A1 (en) * | 2020-01-02 | 2021-07-08 | F. Hoffmann-La Roche Ag | Ada-response specification assay |
| EP4605077A1 (en) | 2022-10-18 | 2025-08-27 | Confo Therapeutics N.V. | Amino acid sequences directed against the melanocortin 4 receptor and polypeptides comprising the same for the treatment of mc4r-related diseases and disorders |
| EP4713364A1 (en) | 2023-05-17 | 2026-03-25 | Odyssey Therapeutics, Inc. | Modified single-domain antibodies |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100081792A1 (en) | 2001-06-28 | 2010-04-01 | Smithkline Beecham Corporation | Ligand |
| AU2002360243A1 (en) | 2001-07-26 | 2003-05-06 | Tanox, Inc. | Agents that activate or inhibit toll-like receptor 9 |
| US20060002935A1 (en) | 2002-06-28 | 2006-01-05 | Domantis Limited | Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor |
| FR2846667B1 (fr) | 2002-11-06 | 2004-12-31 | Pasteur Institut | Fragments variables d'anticorps de camelides a chaine unique diriges contre le peptide beta-amyloide 1-42 et leurs applications pour le diagnostic et le traitement des maladies neuroagregatives |
| WO2004041863A2 (en) | 2002-11-08 | 2004-05-21 | Ablynx N.V. | Single domain antibodies directed against interferon- gamma and uses therefor |
| JP2006517789A (ja) | 2003-01-10 | 2006-08-03 | アブリンクス エン．ヴェー． | 治療用ポリペプチド、その相同物、その断片、および血小板媒介凝集の調節での使用 |
| MX2007006593A (es) | 2004-12-02 | 2008-03-04 | Domantis Ltd | Anticuerpos de dominio simple anti-il 1r1 y sus usos terapeuticos. |
| US8188223B2 (en) | 2005-05-18 | 2012-05-29 | Ablynx N.V. | Serum albumin binding proteins |
| ES2694247T3 (es) | 2005-05-20 | 2018-12-19 | Ablynx N.V. | NanobodiesTM mejorados para el tratamiento de trastornos mediados por agregación |
| WO2006129843A2 (en) | 2005-05-31 | 2006-12-07 | Canon Kabushiki Kaisha | Bispecific capturing molecule |
| JP2009519011A (ja) | 2005-12-01 | 2009-05-14 | ドマンティス リミテッド | インターロイキン１受容体１型に結合する非競合ドメイン抗体フォーマット |
| EA200801166A1 (ru) | 2005-12-01 | 2008-12-30 | Домантис Лимитед | Форматы конкурентного доменного антитела, которые связываются с рецептором интерлейкина 1 первого типа |
| FR2894741B1 (fr) | 2005-12-08 | 2009-12-04 | Centre Nat Etd Spatiales | Chaine de reception par satellite |
| US20100047171A1 (en) | 2006-01-24 | 2010-02-25 | Roland Beckmann | Fusion Proteins That Contain Natural Junctions |
| WO2008020079A1 (en) | 2006-08-18 | 2008-02-21 | Ablynx N.V. | Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling |
| EP2650311A3 (en) | 2007-11-27 | 2014-06-04 | Ablynx N.V. | Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same |
| DE102008023620A1 (de) | 2008-05-15 | 2009-11-19 | Mettler-Toledo (Albstadt) Gmbh | Funktionseinheit mit einer aufrufbaren Funktion und Verfahren zu deren Aufruf |
| EP2285833B1 (en) | 2008-05-16 | 2014-12-17 | Ablynx N.V. | AMINO ACID SEQUENCES DIRECTED AGAINST CXCR4 AND OTHER GPCRs AND COMPOUNDS COMPRISING THE SAME |
| WO2010042815A2 (en) | 2008-10-09 | 2010-04-15 | Duke University | Vhh antibody fragments for use in the detection and treatment of cancer |
| WO2010130832A2 (en) | 2009-05-15 | 2010-11-18 | Ablynx N.V. | Amino acid sequences directed against dickkopf-1 and polypeptides comprising the same for the treatment of diseases and disorders associated with bone loss and/or osteolytic lesions |
| WO2011003622A1 (en) | 2009-07-10 | 2011-01-13 | Ablynx N.V. | Method for the production of variable domains |
| US8306355B2 (en) | 2009-07-13 | 2012-11-06 | Sharp Laboratories Of America, Inc. | Methods and systems for reducing compression artifacts |
| KR101721187B1 (ko) * | 2009-12-23 | 2017-03-29 | 에스바테크 - 어 노바티스 컴파니 엘엘씨 | 면역원성의 감소 방법 |
| JP2013145769A (ja) | 2010-08-04 | 2013-07-25 | Kri Inc | 異方性希土類ボンド磁石とその製造方法 |
| EP2723771B1 (en) | 2011-06-23 | 2019-09-11 | Ablynx NV | Serum albumin binding proteins |
| SG10201805064SA (en) | 2011-06-23 | 2018-07-30 | Ablynx Nv | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
| PE20141522A1 (es) | 2011-08-17 | 2014-11-17 | Glaxo Group Ltd | Proteinas y peptidos modificados |
| US11009511B2 (en) * | 2014-05-16 | 2021-05-18 | Ablynx N.V. | Methods for detecting and/or measuring anti-drug antibodies, in particular treatment-emergent anti-drug antibodies |
-
2015
- 2015-05-13 US US15/311,645 patent/US11009511B2/en active Active
- 2015-05-13 AU AU2015261467A patent/AU2015261467B2/en active Active
- 2015-05-13 HU HUE15723216A patent/HUE056738T2/hu unknown
- 2015-05-13 WO PCT/EP2015/060671 patent/WO2015173342A1/en not_active Ceased
- 2015-05-13 ES ES15723216T patent/ES2900852T3/es active Active
- 2015-05-13 EP EP15723216.6A patent/EP3143403B1/en active Active
- 2015-05-13 EP EP21196545.4A patent/EP3982124A1/en not_active Withdrawn
- 2015-05-13 DK DK15723216.6T patent/DK3143403T3/da active
- 2015-05-13 CA CA2948945A patent/CA2948945C/en active Active
-
2021
- 2021-03-16 AU AU2021201640A patent/AU2021201640B2/en active Active
- 2021-04-13 US US17/229,119 patent/US12553901B2/en active Active
-
2022
- 2022-01-25 CY CY20221100056T patent/CY1125342T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015261467B2 (en) | 2020-12-17 |
| HUE056738T2 (hu) | 2022-03-28 |
| US20170082637A1 (en) | 2017-03-23 |
| US12553901B2 (en) | 2026-02-17 |
| AU2021201640A1 (en) | 2021-04-08 |
| CA2948945C (en) | 2023-08-08 |
| CA2948945A1 (en) | 2015-11-19 |
| US11009511B2 (en) | 2021-05-18 |
| US20210341490A1 (en) | 2021-11-04 |
| CY1125342T1 (el) | 2024-02-16 |
| AU2015261467A1 (en) | 2016-12-01 |
| AU2021201640B2 (en) | 2024-08-01 |
| ES2900852T3 (es) | 2022-03-18 |
| EP3143403A1 (en) | 2017-03-22 |
| WO2015173342A1 (en) | 2015-11-19 |
| EP3982124A1 (en) | 2022-04-13 |
| EP3143403B1 (en) | 2021-10-27 |
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