DK31476A - Olefiniske derivater af aminosyrer og fremgangsmade til deresfremstilling - Google Patents

Olefiniske derivater af aminosyrer og fremgangsmade til deresfremstilling

Info

Publication number
DK31476A
DK31476A DK31476*#A DK31476A DK31476A DK 31476 A DK31476 A DK 31476A DK 31476 A DK31476 A DK 31476A DK 31476 A DK31476 A DK 31476A
Authority
DK
Denmark
Prior art keywords
procedures
preparation
amino acids
olefinic derivatives
olefinic
Prior art date
Application number
DK31476*#A
Other languages
English (en)
Other versions
DK145339C (da
DK145339B (da
Inventor
B W Metcalf
M Jung
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of DK31476A publication Critical patent/DK31476A/da
Publication of DK145339B publication Critical patent/DK145339B/da
Application granted granted Critical
Publication of DK145339C publication Critical patent/DK145339C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK31476A 1975-03-18 1976-01-27 Analogifremgangsmaade til fremstilling af 4-amino-5-hexensyre eller farmaceutisk acceptable salte deraf DK145339C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/559,544 US3960927A (en) 1975-03-18 1975-03-18 Olefinic derivatives of amino acids
US55954475 1975-03-18

Publications (3)

Publication Number Publication Date
DK31476A true DK31476A (da) 1976-09-19
DK145339B DK145339B (da) 1982-11-01
DK145339C DK145339C (da) 1983-03-21

Family

ID=24233995

Family Applications (1)

Application Number Title Priority Date Filing Date
DK31476A DK145339C (da) 1975-03-18 1976-01-27 Analogifremgangsmaade til fremstilling af 4-amino-5-hexensyre eller farmaceutisk acceptable salte deraf

Country Status (20)

Country Link
US (1) US3960927A (da)
JP (1) JPS593988B2 (da)
BE (1) BE839657A (da)
CA (1) CA1077487A (da)
CH (1) CH631696A5 (da)
DE (1) DE2607620C2 (da)
DK (1) DK145339C (da)
ES (1) ES445659A1 (da)
FR (1) FR2304329A1 (da)
GB (1) GB1472525A (da)
IE (1) IE42410B1 (da)
IL (1) IL48912A (da)
MX (1) MX4654E (da)
NL (2) NL187161C (da)
NO (1) NO146428C (da)
NZ (1) NZ179834A (da)
PH (1) PH12100A (da)
PT (1) PT64761B (da)
SE (1) SE442295B (da)
ZA (1) ZA76411B (da)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039549A (en) * 1975-03-18 1977-08-02 Merrell Toraude Et Compagnie Olefinic derivatives of amino acids
US4041041A (en) * 1975-03-18 1977-08-09 Merrell Toraude Et Compagnie Acetylene derivatives of amino acids
US4147873A (en) * 1977-07-01 1979-04-03 Merrell Toraude Et Compagnie α-Vinyl derivatives of α-amino acids
US4139563A (en) * 1977-07-01 1979-02-13 Merrell Toraude Et Compagnie α-ACETYLENIC DERIVATIVES OF AMINES
CA1121375A (en) * 1977-07-01 1982-04-06 Brian W. Metcalf Derivatives of amines and amino acids
CA1157030A (en) * 1977-07-01 1983-11-15 Brian W. Metcalf .alpha.-VINYL AMINO ACIDS
US4326071A (en) * 1977-09-28 1982-04-20 Merrell Toraude Et Compagnie Halomethyl derivatives of gamma-aminobutyric acid and related compounds
US4187316A (en) * 1978-01-12 1980-02-05 Merrell Toraude Et Compagnie Substituted 1,5-cyclohexadiene carboxylic acid derivatives
US4254284A (en) * 1978-01-30 1981-03-03 Merrell Toraude Et Compagnie Process for preparing 4-aminohex-5-ynoic acid
US4178463A (en) * 1978-01-30 1979-12-11 Merrell Toraude Et Compagnie Process for making 4-aminohex-5-enoic acid
US5147868A (en) * 1978-07-24 1992-09-15 Merck & Co., Inc. Thienamycin renal peptidase inhibitors
US4880793A (en) * 1978-07-24 1989-11-14 Merck & Co., Inc. Combination of thienamycin-type antibiotics with dipeptidase inhibitors
US4323704A (en) * 1979-06-25 1982-04-06 Merrell Toraude Et Compagnie αAcetylene and α-vinyl derivatives of amino acids
US4539208A (en) * 1980-09-17 1985-09-03 Merck & Co., Inc. Combination of thienamycin-type antibiotics with dipeptidase inhibitors
US4372974A (en) * 1980-06-25 1983-02-08 New York University Anticonvulsive compositions and method of treating convulsive disorders
GB2120244B (en) * 1982-05-17 1985-05-01 Merrell Toraude & Co Aminoalkadiene derivative
GB2133002B (en) * 1982-12-30 1986-01-29 Merrell Toraude & Co Process for preparing 4-amino-5-hexenoic acid
GB8311804D0 (en) * 1983-04-29 1983-06-02 Merrell Toraude & Co Treatment of seizure disorders and pharmaceutical compositions
CA1252477A (en) * 1983-07-07 1989-04-11 Alexander Krantz .gamma.-ALLENYL-.gamma.-AMINOBUTYRIC ACIDS
US4668703A (en) * 1983-07-07 1987-05-26 Syntex (U.S.A.) Inc. γ-allenyl-γ-aminobutyric acids
US4661510A (en) * 1983-08-17 1987-04-28 Syntex (U.S.A.) Inc. α-allenic-α-amino acids as enzyme inhibitors
US4588825A (en) * 1983-10-11 1986-05-13 Merrell Dow Pharmaceuticals Inc. Intermediates for the synthesis of 4-amino-4,5-dihydro-2-furancarboxylic acid
US4632994A (en) * 1983-11-04 1986-12-30 Gruppo Lepetit S.P.A. Process for decomposing N-oxide derivatives producing 5-vinyl-2-pyrrolidones
JPS6137389U (ja) * 1984-08-09 1986-03-08 永大産業株式会社 家具用の戸
DE3536146A1 (de) * 1985-10-10 1987-04-16 Degussa Verfahren zur enantioselektiven herstellung von (alpha)-vinyl-(alpha)-aminocarbonsaeuren
US4806680A (en) * 1986-03-17 1989-02-21 Merck & Co., Inc. 3-halovinylglycine antibacterial agents
US4727062A (en) * 1986-03-17 1988-02-23 Merck & Co., Inc. 3-Halovinylglycine antibacterial agents
CA2028782C (en) * 1989-11-07 2003-10-14 Christian T. Goralski Process for the production of vinyl-gaba
US5208345A (en) * 1990-12-17 1993-05-04 Merrell Dow Pharmaceuticals Inc. Process for the production of (S)-vinyl and allenyl gaba
AU644919B2 (en) * 1990-12-17 1993-12-23 Aventisub Ii Inc. Process for the production of (S)-vinyl and allenyl gaba
EP0546230A1 (en) * 1991-12-10 1993-06-16 Merrell Dow Pharmaceuticals Inc. Novel process for preparing 4-amino-5-hexenoic acid
US5705660A (en) * 1994-08-22 1998-01-06 Board Of Regents, University Of Nebraska-Lincoln Method for the synthesis of α-oxiranyl amino acids
US7098206B2 (en) * 1998-01-21 2006-08-29 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6998400B2 (en) * 1998-01-22 2006-02-14 Smithkline Beecham Corporation Pharmaceutically active morpholinol
AU2349999A (en) 1998-01-29 1999-08-16 Sepracor, Inc. Pharmacological uses of pure (+) -bupropion
AU2483599A (en) 1998-01-29 1999-08-16 Sepracor, Inc. Pharmaceutical uses of optically pure (-)-bupropion
US6541520B1 (en) 1998-08-05 2003-04-01 Brookhaven Science Associates Treatment of addiction and addiction-related behavior
US6855820B2 (en) * 1999-01-20 2005-02-15 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6734213B2 (en) 1999-01-20 2004-05-11 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6337328B1 (en) * 1999-03-01 2002-01-08 Sepracor, Inc. Bupropion metabolites and methods of use
US6342496B1 (en) 1999-03-01 2002-01-29 Sepracor Inc. Bupropion metabolites and methods of use
CA2430298A1 (en) 2000-11-30 2002-06-06 Banavara Lakshman Mylari Combination of gaba agonists and sorbitol dehydrogenase inhibitors
WO2002043763A2 (en) 2000-11-30 2002-06-06 Pfizer Products Inc. Combination of gaba agonists and aldose reductase inhibitors
CA2525366A1 (en) * 2003-05-16 2004-11-25 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
WO2005082372A1 (en) * 2004-01-29 2005-09-09 Pfizer Products Inc. COMBINATION OF γ-AMINOBUTYRIC ACID MODULATORS AND 5-HT 1B RECEPTOR ANTAGONISTS
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP2275095A3 (en) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
AU2006308889A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
EP2382975A3 (en) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenesis by modulating angiotensin
AU2007292848A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
JP2010521453A (ja) * 2007-03-15 2010-06-24 サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド 新規プロドラッグ
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
EP2537827B1 (en) 2011-06-24 2014-06-11 Targeon SAS Process for preparing 4-amino-5-hexenoic acid from succinimide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2460708A (en) * 1946-03-22 1949-02-01 Merck & Co Inc Process for making acetamido dimethylacrylic acid
US2531595A (en) * 1949-06-09 1950-11-28 Sterling Drug Inc Preparation of alpha-acylamino-alpha-substituted-acetic acids
US2588969A (en) * 1949-11-26 1952-03-11 Eastman Kodak Co Certain acylamino-acrylates and-crotonates as insecticides
US3223729A (en) * 1962-06-06 1965-12-14 Sterling Drug Inc 3-allylhydantoic acid

Also Published As

Publication number Publication date
DE2607620C2 (de) 1984-09-13
MX4654E (es) 1982-07-19
NO146428B (no) 1982-06-21
CA1077487A (en) 1980-05-13
JPS593988B2 (ja) 1984-01-27
PT64761B (en) 1977-06-06
NL187161B (nl) 1991-01-16
BE839657A (fr) 1976-07-16
NZ179834A (en) 1978-06-20
NO760234L (da) 1976-09-21
JPS51125320A (en) 1976-11-01
ES445659A1 (es) 1977-06-01
AU1071676A (en) 1977-08-11
FR2304329B1 (da) 1980-07-18
CH631696A5 (de) 1982-08-31
SE7601205L (sv) 1976-09-19
IE42410B1 (en) 1980-07-30
US3960927A (en) 1976-06-01
DE2607620A1 (de) 1976-09-30
DK145339C (da) 1983-03-21
FR2304329A1 (fr) 1976-10-15
DK145339B (da) 1982-11-01
IE42410L (en) 1976-09-18
NL930125I1 (nl) 1993-11-01
IL48912A0 (en) 1976-03-31
GB1472525A (en) 1977-05-04
PT64761A (en) 1976-03-01
NL930125I2 (nl) 1997-08-01
NL7601116A (nl) 1976-09-21
NO146428C (no) 1982-09-29
NL187161C (nl) 1991-06-17
ZA76411B (en) 1977-01-26
IL48912A (en) 1980-09-16
SE442295B (sv) 1985-12-16
PH12100A (en) 1978-11-02

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Legal Events

Date Code Title Description
CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 1993 00048, 930630

CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 1993 00048, 930630

PUP Patent expired