DK3148541T3 - Thiazolidinoner som cellulære anandamidoptagelseshæmmere og anvendelse deraf i behandling af psykiatriske eller neurologiske forstyrrelser og inflammation, navnlig neuroinflammation - Google Patents

Thiazolidinoner som cellulære anandamidoptagelseshæmmere og anvendelse deraf i behandling af psykiatriske eller neurologiske forstyrrelser og inflammation, navnlig neuroinflammation Download PDF

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Publication number
DK3148541T3
DK3148541T3 DK15725041.6T DK15725041T DK3148541T3 DK 3148541 T3 DK3148541 T3 DK 3148541T3 DK 15725041 T DK15725041 T DK 15725041T DK 3148541 T3 DK3148541 T3 DK 3148541T3
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DK
Denmark
Prior art keywords
inflammation
thiazolidinons
anandamid
neuro
psychiatric
Prior art date
Application number
DK15725041.6T
Other languages
English (en)
Inventor
Jean-Louis Reymond
Jürg Gertsch
Simon Nicolussi
Original Assignee
Univ Bern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP14171022.8A external-priority patent/EP2952188A1/en
Application filed by Univ Bern filed Critical Univ Bern
Application granted granted Critical
Publication of DK3148541T3 publication Critical patent/DK3148541T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK15725041.6T 2014-05-28 2015-05-28 Thiazolidinoner som cellulære anandamidoptagelseshæmmere og anvendelse deraf i behandling af psykiatriske eller neurologiske forstyrrelser og inflammation, navnlig neuroinflammation DK3148541T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14170448 2014-05-28
EP14171022.8A EP2952188A1 (en) 2014-06-03 2014-06-03 Thiazolidinones as cellular anandamide uptake inhibitors and their use in the treatment of psychiatric or neurological disorders and inflammation, in particular neuroinflammation
PCT/EP2015/061914 WO2015181336A1 (en) 2014-05-28 2015-05-28 Thiazolidinones as cellular anandamide uptake inhibitors and their use in the treatment of psychiatric or neurological disorders and inflammation, in particular neuroinflammation

Publications (1)

Publication Number Publication Date
DK3148541T3 true DK3148541T3 (da) 2020-12-07

Family

ID=54698144

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15725041.6T DK3148541T3 (da) 2014-05-28 2015-05-28 Thiazolidinoner som cellulære anandamidoptagelseshæmmere og anvendelse deraf i behandling af psykiatriske eller neurologiske forstyrrelser og inflammation, navnlig neuroinflammation

Country Status (5)

Country Link
US (1) US10300048B2 (da)
EP (1) EP3148541B1 (da)
DK (1) DK3148541T3 (da)
ES (1) ES2845636T3 (da)
WO (1) WO2015181336A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190352297A1 (en) * 2017-01-06 2019-11-21 Universitat Bern Selective aurora a kinase inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43728E1 (en) * 2003-11-21 2012-10-09 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
MX2007001539A (es) 2004-08-10 2007-04-23 Exelisis Inc Compuestos heterociclicos como agentes farmaceuticos.
WO2007059195A1 (en) * 2005-11-14 2007-05-24 University Of Southern California Integrin-binding small molecules
CN101274918A (zh) 2007-03-30 2008-10-01 中国科学院上海药物研究所 一类取代五元杂环化合物,其制备方法和医学用途
WO2009109998A1 (en) * 2008-03-03 2009-09-11 Lupin Limited Novel protein tyrosine phosphatase - ib inhibitors
CN101565408A (zh) 2008-04-25 2009-10-28 国家新药筛选中心 一类受体信号转导增效剂,其制备方法和用途
WO2010136221A1 (en) 2009-05-29 2010-12-02 Dr. August Wolff Gmbh & Co. Kg Arzneimittel Dodeca-2e,4e-diene amides and their use as medicaments and cosmetics
WO2012170839A2 (en) * 2011-06-09 2012-12-13 Cardeus Pharmaceuticals, Inc. Treatment of neuroinflammatory disease with selective cox1 inhibitors
PL3148990T3 (pl) * 2014-05-28 2022-05-30 Universität Bern Związki tiazolidynonu i ich zastosowanie w leczeniu zaburzeń psychiatrycznych neurologicznych i stanów zapalnych, w szczególności stanów zapalnych układu nerwowego

Also Published As

Publication number Publication date
EP3148541B1 (en) 2020-09-02
US20170296515A1 (en) 2017-10-19
US10300048B2 (en) 2019-05-28
ES2845636T3 (es) 2021-07-27
WO2015181336A1 (en) 2015-12-03
EP3148541A1 (en) 2017-04-05

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