DK3150126T3 - Frembringelse af en egnet model til estimering af patientgivet strålingsdosis, der resulterer fra medicinske billedscanninger - Google Patents

Frembringelse af en egnet model til estimering af patientgivet strålingsdosis, der resulterer fra medicinske billedscanninger Download PDF

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DK3150126T3
DK3150126T3 DK16192895.7T DK16192895T DK3150126T3 DK 3150126 T3 DK3150126 T3 DK 3150126T3 DK 16192895 T DK16192895 T DK 16192895T DK 3150126 T3 DK3150126 T3 DK 3150126T3
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image
phantom
scan
dose
simulations
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Gregory Couch
James Couch
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Bayer Healthcare Llc
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/10—Safety means specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/48—Diagnostic techniques
    • A61B6/488—Diagnostic techniques involving pre-scan acquisition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5229—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/54—Control of apparatus or devices for radiation diagnosis
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/58—Testing, adjusting or calibrating thereof
    • A61B6/582—Calibration
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/02—Dosimeters
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
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    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/11—Region-based segmentation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/30—Determination of transform parameters for the alignment of images, i.e. image registration
    • G06T7/33—Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
    • G06T7/337—Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods involving reference images or patches
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/60—Analysis of geometric attributes
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/70—Determining position or orientation of objects or cameras
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/40—Extraction of image or video features
    • G06V10/42—Global feature extraction by analysis of the whole pattern, e.g. using frequency domain transformations or autocorrelation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
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    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10081—Computed x-ray tomography [CT]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS

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Claims (8)

1. Computerimplementeret fremgangsmåde (1000) til bestemmelse af et estimat af strålingsdosis, der er absorberet af et individ ved modtagelse af en billedscanning, hvor fremgangsmåden omfatter: modtagelse (1010) af et sæt af parametre, der beskriver billedscanningen og en billedscanningsanordning, der anvendes til at udføre billedscanningen; modtagelse (1005) af et deformeret fantombillede, der svarer til individet; kendetegnet ved evaluering (1015) af en flerhed af tidligere gennemførte simuleringer, der estimerer strålingsdosisabsorption; og ved bestemmelse (1020), der er baseret på evalueringen, af at to eller flere af simuleringerne matcher til de modtagne sæt af parametre og det modtagne fantombillede inden for en specificeret tolerancemåling, interpolering (1030) af estimaterne af strålingsdosis i de to eller flere simuleringer for at bestemme estimatet af strålingsdosis, der er absorberet af individet ved modtagelse af billedscanningen.
2. Fremgangsmåde ifølge krav 1, der yderligere omfatter, ved bestemmelse af at flerheden af simuleringer ikke indbefatter i det mindste to simuleringer, matchning af de modtagne sæt af parametre og det modtagne fantombillede inden for den specificerede tolerancemåling: udførelse af en simulering af billedscanningen ved anvendelse af det deformerede fantombillede og sættet af parametre; estimering, der er baseret på simuleringen, af mængden af stråling, der er absorberet af individet som et resultat af udførelsen af billedscanningen; og tilføjelse af den udførte simulering til flerheden af simuleringer.
3. Fremgangsmåde ifølge krav2, hvor fantombilledet er deformeret ved bestemmelse, via en billedregistreringsproces, af en transformation mellem i det mindste et lokaliseringsbillede, der er forbundet med fantombilledet og i det mindste et overbliksbillede af individet.
4. Fremgangsmåde ifølge krav 2, hvor fantombilledet er deformeret ved: segmentering af en reference- CT scanning, der forbundet med individet for at identificere en tredimensionel (3D) position af en flerhed af anatomiske vartegn af individet, der er til stede i reference- CT scanningen, matchning af et eller flere af de identificerede anatomiske vartegn i den segmenterede reference- CT scanning til tilsvarende anatomiske vartegn i et første fantombillede; bestemmelse af et tredimensionelt (3D) forskydningskort fra de matchede anatomiske vartegn; voxelisering af det første fantombillede; og transformering af det voxeliserede fantombillede til at matche forskydningskortet.
5. System (130), der omfatter: en processor (305); og en hukommelse (320), der lagrer et applikationsprogram, som er konfigureret til at udføre en operation til bestemmelse af et estimat af strålingsdosis, der er absorberet af et individ ved modtagelse af en billedscanning, hvor operationen omfatter: modtagelse af et sæt af parametre, der beskriver billedscanningen, og en billedscanningsanordning, der anvendes til at udføre billedscanningen, modtagelse af et deformeret fantombillede, der svarer til individet, kendetegnet ved evaluering af en flerhed af tidligere gennemførte simuleringer, der estimerer strålingsdosisabsorption, og ved bestemmelse, der er baseret på evalueringen, af at to eller flere af simuleringerne matcher til de modtagne sæt af parametre og det modtagne fantombillede inden for en specificeret tolerancemåling, interpolering af estimaterne af strålingsdosis i de to eller flere simuleringer for at bestemme estimatet af strålingsdosis, der er absorberet af individet ved modtagelse af billedscanningen.
6. System ifølge krav 5, der yderligere omfatter, ved bestemmelse af at flerheden af simuleringer ikke indbefatter i det mindste to simuleringer, matchning af de modtagne sæt af parametre og det modtagne fantombillede inden for den specificerede tolerancemåling: udførelse af en simulering af billedscanningen ved anvendelse af det deformerede fantombillede og sættet af parametre; estimering, der er baseret på simuleringen, af mængden af stråling, der er absorberet af individet som et resultat af udførelsen af billedscanningen; og tilføjelse af den udførte simulering til flerheden af simuleringer.
7. System ifølge krav 6, hvor fantombilledet er deformeret ved bestemmelse, via en billedregistreringsproces, af en transformation mellem i det mindste et lokaliseringsbillede, der forbundet med fantombilledet, og i det mindste et overbliksbillede af individet.
8. System ifølge krav 6 eller 7, hvor fantombilledet er deformeret ved: segmentering af en reference- CT scanning, der forbundet med individet for at identificere en tredimensionel (3D) position af en flerhed af anatomiske vartegn af individet, der er til stede i reference- CT scanningen, matchning af et eller flere af de identificerede anatomiske vartegn i den segmenterede reference- CT scanning til tilsvarende anatomiske vartegn i et første fantombillede; bestemmelse af et tredimensionelt (3D) forskydningskort fra de matchede anatomiske vartegn; voxelisering af det første fantombillede; og transformering af det voxeliserede fantombillede til at matche forskydningskortet.
DK16192895.7T 2010-12-08 2011-12-08 Frembringelse af en egnet model til estimering af patientgivet strålingsdosis, der resulterer fra medicinske billedscanninger DK3150126T3 (da)

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US42083410P 2010-12-08 2010-12-08
EP11846200.1A EP2648621B1 (en) 2010-12-08 2011-12-08 Generating a suitable model for estimating patient radiation dose resulting from medical imaging scans

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DK17188619.5T DK3281586T3 (da) 2010-12-08 2011-12-08 Generering af et estimat for patientstrålingsdosis som følge af medicinske billeddannelsesscanninger
DK19164751.0T DK3524159T3 (da) 2010-12-08 2011-12-08 Frembringelse af en egnet model til estimering af strålingsdosis modtaget af patient under scanninger til medicinsk billeddannelse
DK11846200.1T DK2648621T3 (da) 2010-12-08 2011-12-08 Generering af en egnet model til estimering af patientstrålingsdosis som følge af medicinske billeddannelsesscanninger
DK16192895.7T DK3150126T3 (da) 2010-12-08 2011-12-08 Frembringelse af en egnet model til estimering af patientgivet strålingsdosis, der resulterer fra medicinske billedscanninger

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DK17188619.5T DK3281586T3 (da) 2010-12-08 2011-12-08 Generering af et estimat for patientstrålingsdosis som følge af medicinske billeddannelsesscanninger
DK19164751.0T DK3524159T3 (da) 2010-12-08 2011-12-08 Frembringelse af en egnet model til estimering af strålingsdosis modtaget af patient under scanninger til medicinsk billeddannelse
DK11846200.1T DK2648621T3 (da) 2010-12-08 2011-12-08 Generering af en egnet model til estimering af patientstrålingsdosis som følge af medicinske billeddannelsesscanninger

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EP (4) EP3524159B1 (da)
JP (4) JP5917552B2 (da)
KR (4) KR101845576B1 (da)
CN (3) CN103442644B (da)
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CA3033428C (en) 2022-03-22
AU2017251775B2 (en) 2019-08-29
JP5917552B2 (ja) 2016-05-18
AU2017251773B2 (en) 2019-08-08
US20120148132A1 (en) 2012-06-14
AU2011340078B2 (en) 2016-06-30

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