DK3170842T3 - Immunologisk effektorcelle af målrettet cld18a2, fremstillingsfremgangsmåde og anvendelse deraf - Google Patents

Immunologisk effektorcelle af målrettet cld18a2, fremstillingsfremgangsmåde og anvendelse deraf Download PDF

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Publication number
DK3170842T3
DK3170842T3 DK15821331.4T DK15821331T DK3170842T3 DK 3170842 T3 DK3170842 T3 DK 3170842T3 DK 15821331 T DK15821331 T DK 15821331T DK 3170842 T3 DK3170842 T3 DK 3170842T3
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cld18a2
targeted
preparation
application
effect cell
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DK15821331.4T
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Huamao Wang
Bo Song
Xiumei Cai
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Carsgen Therapeutics Ltd
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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DK15821331.4T 2014-07-17 2015-07-15 Immunologisk effektorcelle af målrettet cld18a2, fremstillingsfremgangsmåde og anvendelse deraf DK3170842T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410341504.XA CN105315375B (zh) 2014-07-17 2014-07-17 靶向cld18a2的t淋巴细胞及其制备方法和应用
PCT/CN2015/084023 WO2016008405A1 (zh) 2014-07-17 2015-07-15 靶向cld18a2的免疫效应细胞及其制备方法和应用

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DK3170842T3 true DK3170842T3 (da) 2019-10-07

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DK15821331.4T DK3170842T3 (da) 2014-07-17 2015-07-15 Immunologisk effektorcelle af målrettet cld18a2, fremstillingsfremgangsmåde og anvendelse deraf

Country Status (10)

Country Link
US (4) US10377822B2 (da)
EP (1) EP3170842B1 (da)
JP (2) JP2017522024A (da)
KR (1) KR101950747B1 (da)
CN (6) CN120137055A (da)
DK (1) DK3170842T3 (da)
ES (1) ES2746555T3 (da)
PL (1) PL3170842T3 (da)
PT (1) PT3170842T (da)
WO (1) WO2016008405A1 (da)

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CN120137055A (zh) 2014-07-17 2025-06-13 恺兴生命科技(上海)有限公司 靶向cld18a2的t淋巴细胞及其制备方法和应用
WO2016180468A1 (en) * 2015-05-11 2016-11-17 Biontech Cell & Gene Therapies Gmbh Claudin-18.2-specific immunoreceptors and t cell epitopes
CN109414512A (zh) 2016-04-22 2019-03-01 科济生物医药（上海）有限公司 用于细胞免疫疗法的组合物和方法
WO2017186121A1 (zh) * 2016-04-26 2017-11-02 科济生物医药（上海）有限公司 一种改善免疫应答细胞功能的方法
CA3023143A1 (en) 2016-06-15 2017-12-21 Icahn School Of Medicine At Mount Sinai Influenza virus hemagglutinin proteins and uses thereof
CN114891751A (zh) * 2016-06-20 2022-08-12 上海细胞治疗研究院 一种高效稳定表达激活型抗体的car-t细胞及其用途
AU2017294276B2 (en) * 2016-07-08 2024-08-01 Crage Medical Co., Limited Antibody for anti-claudin 18A2 and use thereof
WO2018040537A1 (zh) * 2016-08-31 2018-03-08 南京凯地生物科技有限公司 人pd-1基因敲除的cldn18.2 特异性嵌合抗原受体t细胞的制备方法以及应用
CN106754725A (zh) * 2016-12-26 2017-05-31 北京普瑞金科技有限公司 一种嵌合抗原受体t细胞及其制备方法与应用
WO2018187706A2 (en) 2017-04-07 2018-10-11 Icahn School Of Medicine At Mount Sinai Anti-influenza b virus neuraminidase antibodies and uses thereof
KR20200143672A (ko) 2018-02-02 2020-12-24 카르스젠 테라퓨틱스 컴퍼니, 리미티드 세포 면역 치료의 조합
CN111989344A (zh) 2018-03-09 2020-11-24 科济生物医药（上海）有限公司 用于治疗肿瘤的方法和组合物
CN112074600A (zh) 2018-05-03 2020-12-11 科济生物医药（上海）有限公司 免疫效应细胞及其应用
CA3100446A1 (en) 2018-05-15 2019-11-21 Carsgen Therapeutics Co., Ltd. Genetically engineered cell and application thereof
SG11202007074PA (en) * 2018-05-18 2020-08-28 Lanova Medicines Ltd Company Anti-claudin 18.2 antibodies and uses thereof
CN111867630B (zh) 2018-06-17 2023-10-13 上海健信生物医药科技有限公司 靶向cldn18.2的抗体、双特异性抗体、adc和car及其应用
CN110615842B (zh) * 2018-06-20 2023-05-09 上海隆耀生物科技有限公司 一种包含共刺激受体的嵌合抗原受体及应用
EP3810634A4 (en) 2018-06-21 2022-07-27 Icahn School of Medicine at Mount Sinai Mosaic influenza virus hemagglutinin polypeptides and uses thereof
KR20210055034A (ko) 2018-07-24 2021-05-14 카파 테라퓨틱스 리미티드 면역 이펙터 세포를 사용하여 종양을 치료하는 방법
EP3878863A4 (en) * 2018-08-27 2022-06-22 Nanjing Sanhome Pharmaceutical Co., Ltd. ANTI-CLAUDIN18.2 ANTIBODIES AND ITS USE
US20240165232A1 (en) * 2018-09-24 2024-05-23 Fred Hutchinson Cancer Research Center Chimeric receptor proteins and uses thereof
CN109206524B (zh) * 2018-09-25 2022-04-05 山东兴瑞生物科技有限公司 抗Claudin18A2嵌合抗原受体、其修饰的T细胞及T细胞制备方法和用途
US20230158071A1 (en) 2018-12-07 2023-05-25 Crage Medical Co., Limited Tumor combined immunotherapy
CN113227146B (zh) * 2018-12-28 2024-03-01 南京金斯瑞生物科技有限公司 密蛋白18.2结合部分和其用途
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