DK3186283T3 - Kombinationsbehandling med tumormålrettede IL-2- immuncytokinervarianter og antistoffer mod humant PD-L1 - Google Patents
Kombinationsbehandling med tumormålrettede IL-2- immuncytokinervarianter og antistoffer mod humant PD-L1 Download PDFInfo
- Publication number
- DK3186283T3 DK3186283T3 DK15753700.2T DK15753700T DK3186283T3 DK 3186283 T3 DK3186283 T3 DK 3186283T3 DK 15753700 T DK15753700 T DK 15753700T DK 3186283 T3 DK3186283 T3 DK 3186283T3
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- DK
- Denmark
- Prior art keywords
- immunocytokine
- tumor
- variants
- targeted
- combination therapy
- Prior art date
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C—CHEMISTRY; METALLURGY
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- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- C—CHEMISTRY; METALLURGY
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- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
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- Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
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- Microbiology (AREA)
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- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
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- Toxicology (AREA)
- Gynecology & Obstetrics (AREA)
- Developmental Biology & Embryology (AREA)
- Pregnancy & Childbirth (AREA)
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- Urology & Nephrology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14182778 | 2014-08-29 | ||
| PCT/EP2015/069399 WO2016030350A1 (en) | 2014-08-29 | 2015-08-25 | Combination therapy of tumor-targeted il-2 variant immunocytokines and antibodies against human pd-l1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3186283T3 true DK3186283T3 (da) | 2020-03-02 |
Family
ID=51535312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15753700.2T DK3186283T3 (da) | 2014-08-29 | 2015-08-25 | Kombinationsbehandling med tumormålrettede IL-2- immuncytokinervarianter og antistoffer mod humant PD-L1 |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US20160175397A1 (da) |
| EP (1) | EP3186283B1 (da) |
| JP (3) | JP6603707B2 (da) |
| KR (1) | KR102058846B1 (da) |
| CN (1) | CN106794245B (da) |
| AR (1) | AR101697A1 (da) |
| AU (1) | AU2015308527C1 (da) |
| BR (1) | BR112016030670A2 (da) |
| CA (1) | CA2951604A1 (da) |
| DK (1) | DK3186283T3 (da) |
| ES (1) | ES2774380T3 (da) |
| HR (1) | HRP20200272T1 (da) |
| HU (1) | HUE047806T2 (da) |
| IL (1) | IL249162B (da) |
| LT (1) | LT3186283T (da) |
| MX (1) | MX379475B (da) |
| MY (1) | MY193723A (da) |
| PL (1) | PL3186283T3 (da) |
| PT (1) | PT3186283T (da) |
| RS (1) | RS59939B1 (da) |
| RU (1) | RU2710354C2 (da) |
| SG (1) | SG11201701157UA (da) |
| SI (1) | SI3186283T1 (da) |
| WO (1) | WO2016030350A1 (da) |
Families Citing this family (127)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009333580B2 (en) | 2008-12-09 | 2016-07-07 | Genentech, Inc. | Anti-PD-L1 antibodies and their use to enhance T-cell function |
| US9428567B2 (en) | 2010-12-22 | 2016-08-30 | The Board Of Trustees Of The Leland Stanford Junior University | Antagonists of interleukin-2 receptor |
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| HUE029139T2 (hu) * | 2011-02-10 | 2017-02-28 | Roche Glycart Ag | Mutáns interleukin-2 polipeptidek |
| EP2686345B1 (en) * | 2011-03-16 | 2018-04-25 | Amgen Inc. | Fc variants |
| EA201892619A1 (ru) * | 2011-04-29 | 2019-04-30 | Роше Гликарт Аг | Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2 |
| CN102199218A (zh) * | 2011-04-29 | 2011-09-28 | 中国人民解放军军事医学科学院基础医学研究所 | 一种抗Her2抗体-白细胞介素2融合蛋白及其用途 |
| AR092044A1 (es) * | 2012-08-07 | 2015-03-18 | Roche Glycart Ag | Inmunoterapia mejorada |
| MY193723A (en) * | 2014-08-29 | 2022-10-27 | Hoffmann La Roche | Combination therapy of tumor-targeted il-2 variant immunocytokines and antibodies against human pd-l1 |
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2015
- 2015-08-25 MY MYPI2017700629A patent/MY193723A/en unknown
- 2015-08-25 MX MX2017002426A patent/MX379475B/es unknown
- 2015-08-25 AU AU2015308527A patent/AU2015308527C1/en not_active Ceased
- 2015-08-25 RU RU2017110279A patent/RU2710354C2/ru active
- 2015-08-25 ES ES15753700T patent/ES2774380T3/es active Active
- 2015-08-25 SI SI201531096T patent/SI3186283T1/sl unknown
- 2015-08-25 LT LTEP15753700.2T patent/LT3186283T/lt unknown
- 2015-08-25 SG SG11201701157UA patent/SG11201701157UA/en unknown
- 2015-08-25 HR HRP20200272TT patent/HRP20200272T1/hr unknown
- 2015-08-25 CA CA2951604A patent/CA2951604A1/en not_active Abandoned
- 2015-08-25 PL PL15753700T patent/PL3186283T3/pl unknown
- 2015-08-25 EP EP15753700.2A patent/EP3186283B1/en active Active
- 2015-08-25 CN CN201580039074.9A patent/CN106794245B/zh not_active Expired - Fee Related
- 2015-08-25 DK DK15753700.2T patent/DK3186283T3/da active
- 2015-08-25 BR BR112016030670A patent/BR112016030670A2/pt not_active IP Right Cessation
- 2015-08-25 WO PCT/EP2015/069399 patent/WO2016030350A1/en not_active Ceased
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- 2015-08-25 JP JP2017511708A patent/JP6603707B2/ja not_active Expired - Fee Related
- 2015-08-25 KR KR1020177005273A patent/KR102058846B1/ko not_active Expired - Fee Related
- 2015-08-25 HU HUE15753700A patent/HUE047806T2/hu unknown
- 2015-08-25 RS RS20200202A patent/RS59939B1/sr unknown
- 2015-08-26 AR ARP150102736A patent/AR101697A1/es unknown
- 2015-08-28 US US14/839,410 patent/US20160175397A1/en not_active Abandoned
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2016
- 2016-11-23 IL IL249162A patent/IL249162B/en active IP Right Grant
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2017
- 2017-12-21 US US15/851,253 patent/US20180200338A1/en not_active Abandoned
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2019
- 2019-02-14 JP JP2019024360A patent/JP6594573B2/ja not_active Expired - Fee Related
- 2019-08-15 US US16/542,135 patent/US20190374609A1/en not_active Abandoned
- 2019-10-11 JP JP2019187434A patent/JP2020033362A/ja active Pending
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