DK3200771T3 - Direkte kompressionshjælpestof på basis af lactose, cellulose og stivelse - Google Patents

Direkte kompressionshjælpestof på basis af lactose, cellulose og stivelse Download PDF

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Publication number
DK3200771T3
DK3200771T3 DK15778237.6T DK15778237T DK3200771T3 DK 3200771 T3 DK3200771 T3 DK 3200771T3 DK 15778237 T DK15778237 T DK 15778237T DK 3200771 T3 DK3200771 T3 DK 3200771T3
Authority
DK
Denmark
Prior art keywords
lactose
starch
cellulose
direct compression
aid based
Prior art date
Application number
DK15778237.6T
Other languages
English (en)
Inventor
Eugen Schwarz
Vera Fichtner
Original Assignee
Molkerei Meggle Wasserburg Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molkerei Meggle Wasserburg Gmbh & Co Kg filed Critical Molkerei Meggle Wasserburg Gmbh & Co Kg
Application granted granted Critical
Publication of DK3200771T3 publication Critical patent/DK3200771T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK15778237.6T 2014-09-30 2015-09-29 Direkte kompressionshjælpestof på basis af lactose, cellulose og stivelse DK3200771T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14187045.1A EP3002005A1 (en) 2014-09-30 2014-09-30 Direct compression excipient based on lactose, cellulose and starch
PCT/EP2015/072420 WO2016050768A1 (en) 2014-09-30 2015-09-29 Direct compression excipient based on lactose, cellulose and starch

Publications (1)

Publication Number Publication Date
DK3200771T3 true DK3200771T3 (da) 2020-10-26

Family

ID=51625954

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15778237.6T DK3200771T3 (da) 2014-09-30 2015-09-29 Direkte kompressionshjælpestof på basis af lactose, cellulose og stivelse

Country Status (7)

Country Link
US (1) US10058508B2 (da)
EP (2) EP3002005A1 (da)
BR (1) BR112017006075A2 (da)
DK (1) DK3200771T3 (da)
ES (1) ES2829873T3 (da)
PT (1) PT3200771T (da)
WO (1) WO2016050768A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106344928A (zh) * 2016-08-31 2017-01-25 安徽逸能生物科技有限公司 一种变性淀粉在医药中的应用
CN113456639B (zh) * 2020-03-31 2024-01-26 江苏康缘药业股份有限公司 一种抗心律失常的药物组合物及制备方法
CN112076166A (zh) * 2020-09-21 2020-12-15 湖州展望药业有限公司 一种直压淀粉及其生产方法
CN114796507A (zh) * 2022-03-31 2022-07-29 江苏西典药用辅料有限公司 一种乳糖、微晶纤维素共处理物的制备工艺
WO2026068479A1 (en) 2024-09-24 2026-04-02 Meggle Group GmbH Novel tabletting excipient and method of manufacture

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3433239A1 (de) * 1984-09-11 1986-03-20 Bayer Ag, 5090 Leverkusen Feste arzneizubereitung enthaltend nitrendipin und verfahren zu ihrer herstellung
DE3506276C1 (de) 1985-02-22 1986-04-24 Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring Direkttablettiermittel
DK0812195T3 (da) * 1995-02-28 2003-03-03 Aventis Pharma Inc Farmaceutisk sammensætning til piperidinoalkanolforbindelser
JP2001505899A (ja) 1996-12-12 2001-05-08 デーデーエス ドラッグ デリバリー サービス ゲセルシャフト ツーア フェアデルング デア フォルシュング イン ファーマシューティッシャー テクノロジー ウント バイオファーマジー エムベーハー 任意に活性物質を含むマトリクス材料−賦形剤コンパウンドの形態の処方物
GB9914936D0 (en) * 1999-06-26 1999-08-25 Cerestar Holding Bv Directly compressible starch as enhancer of properties of excipients when used as binder and disintegrant for compression tablets
ES2292414T3 (es) 2000-07-27 2008-03-16 Roquette Freres Granulos a base de almidon y de lactosa.
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
IS6633A (is) * 2002-11-22 2004-05-23 Omega Farma Ehf. Samsetningar af fínasteríð töflum
DE602005020516D1 (de) 2004-12-22 2010-05-20 Campina Nederland Holding Bv Wasserfreie lactoseagglomerate und deren herstellung
DE602006004694D1 (de) * 2006-01-05 2009-02-26 Teva Pharma Feuchtgranulierungsmethode zur Herstellung pharmazeutischer Aripiprazolzusammensetzungen
CN103751186B (zh) * 2006-04-05 2016-08-24 欧科生医股份有限公司 药物制剂：8-[{1-(3,5-双-(三氟甲基)苯基)-乙氧基}-甲基]-8-苯基-1,7-二氮杂-螺[4.5]癸-2-酮的盐及用其治疗的方法
JP5714600B2 (ja) 2009-12-18 2015-05-07 フリースランドカンピナ・ネーデルランド・ホールディング・ビー．ブイ．ＦｒｉｅｓｌａｎｄＣａｍｐｉｎａ Ｎｅｄｅｒｌａｎｄ Ｈｏｌｄｉｎｇ Ｂ．Ｖ． 共加工された錠用賦形剤混合物、その調製及び使用
US9561186B2 (en) * 2012-11-30 2017-02-07 Pharmathen S.A. Method for improving the bioavailability of low aqueous solubility drugs

Also Published As

Publication number Publication date
ES2829873T3 (es) 2021-06-02
BR112017006075A2 (pt) 2017-12-19
EP3200771A1 (en) 2017-08-09
EP3200771B1 (en) 2020-10-14
WO2016050768A1 (en) 2016-04-07
PT3200771T (pt) 2020-11-10
EP3002005A1 (en) 2016-04-06
US20170216209A1 (en) 2017-08-03
US10058508B2 (en) 2018-08-28

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