DK3207053T3 - Hidtil ukendte immunogene peptider - Google Patents

Hidtil ukendte immunogene peptider Download PDF

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Publication number
DK3207053T3
DK3207053T3 DK15787917T DK15787917T DK3207053T3 DK 3207053 T3 DK3207053 T3 DK 3207053T3 DK 15787917 T DK15787917 T DK 15787917T DK 15787917 T DK15787917 T DK 15787917T DK 3207053 T3 DK3207053 T3 DK 3207053T3
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Prior art keywords
immunogenic peptides
new immunogenic
new
peptides
immunogenic
Prior art date
Application number
DK15787917T
Other languages
English (en)
Inventor
Jean-Marie Saint-Remy
Vincent Carlier
Elst Luc Vander
David Burkhart
Original Assignee
Imcyse Sa Giga B34
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imcyse Sa Giga B34 filed Critical Imcyse Sa Giga B34
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Publication of DK3207053T3 publication Critical patent/DK3207053T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70539MHC-molecules, e.g. HLA-molecules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/64Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Rehabilitation Therapy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
DK15787917T 2014-10-17 2015-10-16 Hidtil ukendte immunogene peptider DK3207053T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1418433.7A GB201418433D0 (en) 2014-10-17 2014-10-17 Novel immunogenic peptides
PCT/EP2015/074063 WO2016059236A1 (en) 2014-10-17 2015-10-16 Novel immunogenic peptides

Publications (1)

Publication Number Publication Date
DK3207053T3 true DK3207053T3 (da) 2019-11-04

Family

ID=52013133

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15787917T DK3207053T3 (da) 2014-10-17 2015-10-16 Hidtil ukendte immunogene peptider

Country Status (16)

Country Link
US (3) US20180228912A1 (da)
EP (2) EP3207053B1 (da)
JP (2) JP6655626B2 (da)
KR (1) KR102556485B1 (da)
CN (1) CN107148427B (da)
AU (2) AU2015332621B2 (da)
BR (1) BR112017007773A2 (da)
CA (1) CA2964426C (da)
DK (1) DK3207053T3 (da)
ES (1) ES2751605T3 (da)
GB (1) GB201418433D0 (da)
MX (1) MX374635B (da)
PL (1) PL3207053T3 (da)
PT (1) PT3207053T (da)
RU (1) RU2709711C2 (da)
WO (1) WO2016059236A1 (da)

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EP3592765A1 (en) 2017-03-09 2020-01-15 ImCyse SA Peptides and methods for the treatment of diabetes
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US20230113747A1 (en) 2019-05-16 2023-04-13 Imcyse Sa Immunogenic peptides with an oxidoreductase motif comprising a modified cysteine

Also Published As

Publication number Publication date
US20240342297A1 (en) 2024-10-17
PT3207053T (pt) 2019-11-15
BR112017007773A2 (pt) 2018-01-16
MX374635B (es) 2025-03-06
EP3207053B1 (en) 2019-08-21
CA2964426A1 (en) 2016-04-21
JP2020079271A (ja) 2020-05-28
PL3207053T3 (pl) 2020-05-18
US20200397911A1 (en) 2020-12-24
AU2015332621B2 (en) 2019-07-18
EP3207053A1 (en) 2017-08-23
RU2017111657A (ru) 2018-11-19
EP3636666A1 (en) 2020-04-15
RU2709711C2 (ru) 2019-12-19
RU2017111657A3 (da) 2019-05-29
JP2018504419A (ja) 2018-02-15
KR20170069266A (ko) 2017-06-20
KR102556485B1 (ko) 2023-07-17
AU2015332621A1 (en) 2017-04-13
CA2964426C (en) 2023-01-24
JP6655626B2 (ja) 2020-02-26
US20180228912A1 (en) 2018-08-16
MX2017004780A (es) 2017-11-30
ES2751605T3 (es) 2020-04-01
US12023384B2 (en) 2024-07-02
GB201418433D0 (en) 2014-12-03
CN107148427A (zh) 2017-09-08
CN107148427B (zh) 2021-08-13
AU2019250206A1 (en) 2019-11-07
WO2016059236A1 (en) 2016-04-21

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