DK320786A - Vaccine - Google Patents

Vaccine Download PDF

Info

Publication number
DK320786A
DK320786A DK320786A DK320786A DK320786A DK 320786 A DK320786 A DK 320786A DK 320786 A DK320786 A DK 320786A DK 320786 A DK320786 A DK 320786A DK 320786 A DK320786 A DK 320786A
Authority
DK
Denmark
Prior art keywords
toxin
polysaccharide
conjugate
antibody
tetanus toxoid
Prior art date
Application number
DK320786A
Other languages
English (en)
Other versions
DK163176B (da
DK320786D0 (da
DK163176C (da
Inventor
Stanley J Cryz
Emil Fuerer
Original Assignee
Schweiz Serum & Impfinst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schweiz Serum & Impfinst filed Critical Schweiz Serum & Impfinst
Publication of DK320786D0 publication Critical patent/DK320786D0/da
Publication of DK320786A publication Critical patent/DK320786A/da
Publication of DK163176B publication Critical patent/DK163176B/da
Application granted granted Critical
Publication of DK163176C publication Critical patent/DK163176C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/104—Pseudomonadales, e.g. Pseudomonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DK320786A 1985-09-27 1986-07-04 Ugiftig konjugatvaccine mod infektioner af pseudomonas aeruginosa- og escherichia coli- bakterier, fremgangsmaade til fremstilling heraf og anvendelse af vaccinen DK163176C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH419985 1985-09-27
CH419985 1985-09-27

Publications (4)

Publication Number Publication Date
DK320786D0 DK320786D0 (da) 1986-07-04
DK320786A true DK320786A (da) 1987-03-28
DK163176B DK163176B (da) 1992-02-03
DK163176C DK163176C (da) 1992-06-22

Family

ID=4271640

Family Applications (1)

Application Number Title Priority Date Filing Date
DK320786A DK163176C (da) 1985-09-27 1986-07-04 Ugiftig konjugatvaccine mod infektioner af pseudomonas aeruginosa- og escherichia coli- bakterier, fremgangsmaade til fremstilling heraf og anvendelse af vaccinen

Country Status (11)

Country Link
US (1) US4771127A (da)
EP (1) EP0220387B1 (da)
JP (1) JPH0662434B2 (da)
AT (1) ATE56615T1 (da)
AU (1) AU587865B2 (da)
CA (1) CA1276552C (da)
DE (1) DE3674328D1 (da)
DK (1) DK163176C (da)
ES (1) ES2000140A6 (da)
PT (1) PT83096B (da)
ZA (1) ZA866564B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5360897A (en) * 1981-08-31 1994-11-01 The University Of Rochester Immunogenic conjugates of streptococcus pneumonial capsular polymer and toxin or in toxiad
US5057301A (en) * 1988-04-06 1991-10-15 Neorx Corporation Modified cellular substrates used as linkers for increased cell retention of diagnostic and therapeutic agents
JP2639416B2 (ja) * 1988-04-23 1997-08-13 財団法人化学及血清療法研究所 真珠生産用二枚貝の血球活性化製剤および該製剤を用いる真珠の生産方法
NZ239643A (en) * 1990-09-17 1996-05-28 North American Vaccine Inc Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group.
US6139843A (en) * 1991-04-02 2000-10-31 Albert Einstein College Of Medicine Of Yeshiva University Peptide compositions for the treatment of HIV
US5370872A (en) * 1991-08-12 1994-12-06 Swiss Serum And Vaccine Institute Berne Escherichia coliO-polysaccharide-protein conjugate vaccine
ES2126616T3 (es) * 1992-10-27 1999-04-01 American Cyanamid Co Vacuna pediatrica combinada, con una inmunogenecidad aumentada de cada componente de la vacuna.
US5554730A (en) * 1993-03-09 1996-09-10 Middlesex Sciences, Inc. Method and kit for making a polysaccharide-protein conjugate
US5866132A (en) * 1995-06-07 1999-02-02 Alberta Research Council Immunogenic oligosaccharide compositions
US5695768A (en) * 1995-06-07 1997-12-09 Alberta Research Council Immunostimulating activity of Streptococcus pneumoniae serotype 8 oligosaccharides
US6749831B1 (en) 1997-05-16 2004-06-15 Medical Defense Technology, Llc Vaccine against lipopolysaccharide core
KR100680014B1 (ko) * 1997-10-03 2007-02-09 갈레니카 파마슈티칼스 인크. 이민 형성 폴리사카라이드, 이의 제조 방법 및 이것의 아쥬반트 및 면역자극제로서의 용도
WO1999055715A2 (en) 1998-04-28 1999-11-04 Galenica Pharmaceuticals, Inc. Polysaccharide-antigen conjugates
US7749511B2 (en) 2000-04-18 2010-07-06 Endobiologics, Incorporated Anti-sepsis conjugate vaccine
EP1278548A2 (en) * 2000-04-18 2003-01-29 Endobiologics, Incorporated Lipopolysaccharide-conjugate vaccine for sepsis treatment
US8048432B2 (en) 2003-08-06 2011-11-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Polysaccharide-protein conjugate vaccines
CA2844154C (en) * 2003-08-06 2016-12-20 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Polysaccharide-protein conjugate vaccines
WO2005117965A1 (en) * 2004-06-04 2005-12-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Methods for preparing immunogenic conjugates
US7625736B2 (en) * 2004-06-04 2009-12-01 The United States Of America As Represented By The Department Of Health And Human Services Methods for preparing immunogenic conjugates
WO2010046778A2 (en) * 2008-10-21 2010-04-29 International Vaccine Institute Novel shigella frotein antigens and methods
CN101912609B (zh) * 2009-08-20 2012-02-01 成都蓉生药业有限责任公司 防治绿脓杆菌感染的组合物及其制备方法
US9416173B2 (en) 2011-04-21 2016-08-16 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Peptide and conjugate vaccines for fungal infections

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4619828A (en) * 1982-07-06 1986-10-28 Connaught Laboratories, Inc. Polysaccharide exotoxoid conjugate vaccines
US4663160A (en) * 1983-03-14 1987-05-05 Miles Laboratories, Inc. Vaccines for gram-negative bacteria
US4693891A (en) * 1985-09-09 1987-09-15 Miles Laboratories, Inc. Vaccine for Pseudomonas aeruginosa
US4707543A (en) * 1985-09-17 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines

Also Published As

Publication number Publication date
AU587865B2 (en) 1989-08-31
DE3674328D1 (de) 1990-10-25
DK163176B (da) 1992-02-03
EP0220387A2 (de) 1987-05-06
AU6322986A (en) 1987-04-02
PT83096A (en) 1986-08-01
US4771127A (en) 1988-09-13
DK320786D0 (da) 1986-07-04
JPH0662434B2 (ja) 1994-08-17
ATE56615T1 (de) 1990-10-15
ES2000140A6 (es) 1987-12-16
ZA866564B (en) 1987-05-27
EP0220387A3 (en) 1989-03-22
EP0220387B1 (de) 1990-09-19
JPS6289632A (ja) 1987-04-24
DK163176C (da) 1992-06-22
CA1276552C (en) 1990-11-20
PT83096B (pt) 1988-07-01

Similar Documents

Publication Publication Date Title
DK320786D0 (da) Vaccine
CA1336308C (en) Polysaccharide-protein conjugates
US4356170A (en) Immunogenic polysaccharide-protein conjugates
US5370872A (en) Escherichia coliO-polysaccharide-protein conjugate vaccine
Cryz et al. Safety and immunogenicity of a Pseudomonas aeruginosa O-polysaccharide toxin A conjugate vaccine in humans.
KR100593466B1 (ko) 다당류-펩타이드접합체
KR920003982A (ko) 면역원성 콘쥬게이트 및 이를 함유하는 백신 조성물
DK93584A (da) Haemophilus-b-influenza polysaccharid exotoxoid-konjugatvaccine
AU740784B2 (en) Coupling of unmodified proteins to haloacyl or dihaloacyl derivatized polysaccharides for the preparation of protein-polysaccharide vaccines
LU91924I2 (fr) Composition vaccinale comprenant le polysaccharidecapsulaire et Haemophilus influenzae type b coupl é à l'anatoxine tétanique, l'antigène diphtérique,l'antigène tétanique, des antigènes de la polio, des antigènes de la coqueluche et du phosphate d'aluminium
US20060134141A1 (en) Glycoconjugate vaccines containing peptidoglycan
KR970705410A (ko) 폐렴구균 감염에 대한 면역용 폐렴구균 다당류-재조합 뉴모리신 결합체 백신(pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections)
CA2071811A1 (en) Improved meningococcal polysaccharide conjugate vaccine
Seid et al. Preparation and characterization of detoxified lipopolysaccharide-protein conjugates.
CA2145397A1 (en) Group b streptococcus type ii and type v polysaccharide-protein conjugate vaccines
Midwinter et al. Vaccination of mice with lipopolysaccharide (LPS) and LPS-derived immuno-conjugates from Leptospira interrogans
WO1994010317A3 (en) Conjugate vaccine against group b streptococcus
AU678549B2 (en) Detoxified LPS-cholera toxin conjugate vaccine for prevention of cholera
Singh et al. Protective efficacy and immunogenicity of Vi-porin conjugate against Salmonella typhi
Tsay et al. Preparation and characterization of a nontoxic polysaccharide-protein conjugate that induces active immunity and passively protective antibody against Pseudomonas aeruginosa immunotype 1 in mice
Polotsky et al. Comparison of conjugates composed of lipopolysaccharide from Shigella flexneri type 2a detoxified by two methods and bound to tetanus toxoid
Aron et al. Salmonella typhi O: 9, 12 polysaccharide-protein conjugates: characterization and immunoreactivity with pooled and individual normal human sera, sera from patients with paratyphoid A and B and typhoid fever, and animal sera
MXPA98007617A (es) Conjugados de polisacaridos peptidos

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK