DK3216780T3 - Fremgangsmåde til fremstilling af organisk fluorid-alifatisk forbindelse og fremgangsmåde til oprensning af organisk fluorid-alifatisk forbindelse - Google Patents
Fremgangsmåde til fremstilling af organisk fluorid-alifatisk forbindelse og fremgangsmåde til oprensning af organisk fluorid-alifatisk forbindelse Download PDFInfo
- Publication number
- DK3216780T3 DK3216780T3 DK15856189.4T DK15856189T DK3216780T3 DK 3216780 T3 DK3216780 T3 DK 3216780T3 DK 15856189 T DK15856189 T DK 15856189T DK 3216780 T3 DK3216780 T3 DK 3216780T3
- Authority
- DK
- Denmark
- Prior art keywords
- aliphatic compound
- organic fluoride
- purification
- preparation
- fluoride
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 238000002360 preparation method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/38—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/38—Separation; Purification; Stabilisation; Use of additives
- C07C17/383—Separation; Purification; Stabilisation; Use of additives by distillation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/38—Separation; Purification; Stabilisation; Use of additives
- C07C17/389—Separation; Purification; Stabilisation; Use of additives by adsorption on solids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C19/00—Acyclic saturated compounds containing halogen atoms
- C07C19/08—Acyclic saturated compounds containing halogen atoms containing fluorine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C21/00—Acyclic unsaturated compounds containing halogen atoms
- C07C21/02—Acyclic unsaturated compounds containing halogen atoms containing carbon-to-carbon double bonds
- C07C21/18—Acyclic unsaturated compounds containing halogen atoms containing carbon-to-carbon double bonds containing fluorine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/34—Separation; Purification; Stabilisation; Use of additives
- C07C41/36—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20140154592 | 2014-11-07 | ||
| KR1020140154593A KR101519425B1 (ko) | 2014-11-07 | 2014-11-07 | 역류방지 반응용기를 포함하는 카세트를 이용한 방사성 의약품의 제조방법 |
| KR1020150126731A KR101605291B1 (ko) | 2014-11-07 | 2015-09-08 | 유기 플루오르화 지방족 화합물의 제조방법 및 정제방법 |
| PCT/KR2015/011955 WO2016072801A1 (ko) | 2014-11-07 | 2015-11-06 | 유기 플루오르화 지방족 화합물의 제조방법 및 정제방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3216780T3 true DK3216780T3 (da) | 2021-01-11 |
| DK3216780T5 DK3216780T5 (da) | 2021-03-15 |
Family
ID=55909438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15856189.4T DK3216780T5 (da) | 2014-11-07 | 2015-11-06 | Fremgangsmåde til fremstilling af organisk fluorid-alifatisk forbindelse og fremgangsmåde til oprensning af organisk fluorid-alifatisk forbindelse |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10525151B2 (da) |
| EP (1) | EP3216780B1 (da) |
| JP (1) | JP6605034B2 (da) |
| CN (2) | CN111574515B (da) |
| AU (1) | AU2015343906B2 (da) |
| CA (1) | CA2971382C (da) |
| DK (1) | DK3216780T5 (da) |
| ES (1) | ES2838752T3 (da) |
| RU (1) | RU2710558C2 (da) |
| WO (1) | WO2016072801A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101842989B1 (ko) * | 2018-01-02 | 2018-03-28 | (주)퓨쳐켐 | 카보닐기를 갖는 알코올 용매를 이용한 플루오르화 화합물의 제조방법 |
| CN115160308A (zh) * | 2022-08-08 | 2022-10-11 | 江苏华益科技有限公司 | 一种18f-fpcit的自动化合成方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2224165A1 (en) * | 1996-04-09 | 1997-10-16 | Yamasa Corporation | 9-(2-deoxy-2-fluoro-4-thio-.beta.-d-arabinofuranosyl)purine derivatives |
| KR100549213B1 (ko) | 2003-01-15 | 2006-02-03 | 학교법인 인하학원 | 플루오린-18로 표지된 유기플루오로화합물의 제조방법 |
| KR100789847B1 (ko) * | 2004-12-15 | 2007-12-28 | (주)퓨쳐켐 | 알코올 용매하에서 유기플루오로 화합물의 제조방법 |
| JP4287502B2 (ja) * | 2006-09-06 | 2009-07-01 | 日本メジフィジックス株式会社 | 放射性フッ素標識有機化合物の製造方法、合成装置およびプログラム |
| KR101009712B1 (ko) | 2007-02-22 | 2011-01-19 | 재단법인 아산사회복지재단 | 양성자성 용매와 이에 녹는 염들을 이용한 음이온 교환고분자 지지체로부터의 플루오린-18 플루오라이드 용리와이를 이용한 플루오린-18의 표지방법 |
| CN101104627A (zh) * | 2007-07-20 | 2008-01-16 | 张锦明 | 18f－fdg自动化合成方法及设备 |
| EP2238074A2 (en) * | 2008-01-03 | 2010-10-13 | GE Healthcare UK Limited | Fluoride processing method |
| CN101585816B (zh) * | 2008-05-20 | 2011-04-20 | 中国科学院上海应用物理研究所 | 一种苯磺酰胺类羟基衍生物及其中间体及制备方法和应用 |
| CN103442738A (zh) * | 2010-09-09 | 2013-12-11 | 皮拉马影像股份公司 | 快速制备用于亲核[18f]氟化的适当[18f]氟化物的方法 |
| WO2012081880A2 (ko) * | 2010-12-14 | 2012-06-21 | 서강대학교산학협력단 | 18f 방사성의약품 제조를 위한 고체 지지체에 연결된 전구체 화합물, 이의 제조방법 및 응용 |
| CN103380058A (zh) | 2010-12-27 | 2013-10-30 | 通用电气健康护理有限公司 | 放射性药物制造和装置 |
| CN102336678A (zh) * | 2011-07-13 | 2012-02-01 | 中国人民解放军总医院 | 一种制备18f-fet的方法 |
| US20140213757A1 (en) | 2011-09-30 | 2014-07-31 | Ge Healthcare Limited | Cassette for radiopharmaceutical synthesis |
| KR101326000B1 (ko) | 2012-01-30 | 2013-11-07 | 재단법인 아산사회복지재단 | 수소이온 농도가 조절된 플루오린-18의 용리액 제조 및 이를 이용한 플루오린-18의 표지방법 |
| KR20130087816A (ko) | 2012-01-30 | 2013-08-07 | 재단법인 아산사회복지재단 | 방사성 동위원소 플루오린-18이 표지된 유기플루오로화합물의 제조방법 |
| US9468692B2 (en) * | 2014-01-23 | 2016-10-18 | General Electric Company | Labeled molecular imaging agents and methods of use |
-
2015
- 2015-11-06 DK DK15856189.4T patent/DK3216780T5/da active
- 2015-11-06 WO PCT/KR2015/011955 patent/WO2016072801A1/ko not_active Ceased
- 2015-11-06 AU AU2015343906A patent/AU2015343906B2/en active Active
- 2015-11-06 ES ES15856189T patent/ES2838752T3/es active Active
- 2015-11-06 EP EP15856189.4A patent/EP3216780B1/en active Active
- 2015-11-06 CN CN202010460956.5A patent/CN111574515B/zh active Active
- 2015-11-06 JP JP2017543693A patent/JP6605034B2/ja active Active
- 2015-11-06 CN CN201580065240.2A patent/CN107001213B/zh active Active
- 2015-11-06 RU RU2017120040A patent/RU2710558C2/ru active
- 2015-11-06 CA CA2971382A patent/CA2971382C/en active Active
- 2015-11-06 US US15/524,705 patent/US10525151B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN107001213B (zh) | 2021-01-15 |
| EP3216780A1 (en) | 2017-09-13 |
| ES2838752T3 (es) | 2021-07-02 |
| AU2015343906A1 (en) | 2017-06-15 |
| CA2971382A1 (en) | 2016-05-12 |
| AU2015343906B2 (en) | 2020-07-23 |
| EP3216780B1 (en) | 2020-10-07 |
| RU2017120040A3 (da) | 2019-06-06 |
| CA2971382C (en) | 2023-03-07 |
| CN107001213A (zh) | 2017-08-01 |
| CN111574515B (zh) | 2023-01-10 |
| JP6605034B2 (ja) | 2019-11-13 |
| RU2710558C2 (ru) | 2019-12-27 |
| JP2017535605A (ja) | 2017-11-30 |
| WO2016072801A1 (ko) | 2016-05-12 |
| RU2017120040A (ru) | 2018-12-10 |
| US10525151B2 (en) | 2020-01-07 |
| EP3216780A4 (en) | 2019-02-20 |
| DK3216780T5 (da) | 2021-03-15 |
| CN111574515A (zh) | 2020-08-25 |
| US20170319720A1 (en) | 2017-11-09 |
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