DK3234187T3 - Fremgangsmåde til enkeltmolekyleanbringelse på et substrat - Google Patents
Fremgangsmåde til enkeltmolekyleanbringelse på et substrat Download PDFInfo
- Publication number
- DK3234187T3 DK3234187T3 DK15820734.0T DK15820734T DK3234187T3 DK 3234187 T3 DK3234187 T3 DK 3234187T3 DK 15820734 T DK15820734 T DK 15820734T DK 3234187 T3 DK3234187 T3 DK 3234187T3
- Authority
- DK
- Denmark
- Prior art keywords
- substrate
- single molecule
- molecule placement
- placement
- molecule
- Prior art date
Links
- 239000000758 substrate Substances 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462092171P | 2014-12-15 | 2014-12-15 | |
| PCT/US2015/065526 WO2016100196A1 (en) | 2014-12-15 | 2015-12-14 | Compositions and methods for single molecular placement on a substrate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3234187T3 true DK3234187T3 (da) | 2021-05-25 |
Family
ID=55071188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15820734.0T DK3234187T3 (da) | 2014-12-15 | 2015-12-14 | Fremgangsmåde til enkeltmolekyleanbringelse på et substrat |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10350570B2 (da) |
| EP (2) | EP3234187B1 (da) |
| CN (2) | CN114438172B (da) |
| DK (1) | DK3234187T3 (da) |
| ES (1) | ES2870097T3 (da) |
| PL (1) | PL3234187T3 (da) |
| PT (1) | PT3234187T (da) |
| WO (1) | WO2016100196A1 (da) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2625288T3 (es) | 2011-04-15 | 2017-07-19 | The Johns Hopkins University | Sistema de secuenciación segura |
| AU2013338393C1 (en) | 2012-10-29 | 2024-07-25 | The Johns Hopkins University | Papanicolaou test for ovarian and endometrial cancers |
| EP3234187B1 (en) * | 2014-12-15 | 2021-02-17 | Illumina, Inc. | Method for single molecular placement on a substrate |
| US11286531B2 (en) | 2015-08-11 | 2022-03-29 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| US11118206B2 (en) * | 2016-01-13 | 2021-09-14 | The Trustees Of The University Of Pennsylvania | Multiple stage isothermal enzymatic amplification |
| EP3472351B1 (de) | 2016-06-15 | 2020-10-28 | Ludwig-Maximilians-Universität München | Einzelmolekülnachweis bzw. -quantifizierung durch dna-nanotechnologie |
| WO2018071522A1 (en) * | 2016-10-11 | 2018-04-19 | Life Technologies Corporation | Rapid amplification of nucleic acids |
| GB201704754D0 (en) | 2017-01-05 | 2017-05-10 | Illumina Inc | Kinetic exclusion amplification of nucleic acid libraries |
| IL319255A (en) | 2017-08-07 | 2025-04-01 | Univ Johns Hopkins | Methods and materials for cancer assessment and treatment |
| US11009433B2 (en) * | 2018-03-02 | 2021-05-18 | iSun Technology LTD. | Composition and method for solid-state tissue clearing |
| SG11202011240YA (en) * | 2018-06-26 | 2020-12-30 | Broad Inst Inc | Crispr/cas and transposase based amplification compositions, systems and methods |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| US12529094B2 (en) | 2018-12-10 | 2026-01-20 | 10X Genomics, Inc. | Imaging system hardware |
| EP3894590B1 (en) * | 2018-12-10 | 2025-10-22 | 10X Genomics, Inc. | Methods of using master / copy arrays for spatial detection |
| CN109837277A (zh) * | 2019-03-01 | 2019-06-04 | 深圳生生凡非基因技术有限公司 | 一种cpgk嵌合型启动子、腺相关病毒载体及其应用 |
| EP3976820A1 (en) | 2019-05-30 | 2022-04-06 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| US11905532B2 (en) * | 2019-06-25 | 2024-02-20 | Massachusetts Institute Of Technology | Compositions and methods for molecular memory storage and retrieval |
| TWI886183B (zh) * | 2019-12-18 | 2025-06-11 | 美商伊路米納有限公司 | 成像系統及成像方法 |
| CN115135984B (zh) | 2019-12-23 | 2025-12-23 | 10X基因组学有限公司 | 可逆固定试剂及其使用方法 |
| EP4081656A1 (en) | 2019-12-23 | 2022-11-02 | 10X Genomics, Inc. | Compositions and methods for using fixed biological samples in partition-based assays |
| US12365942B2 (en) | 2020-01-13 | 2025-07-22 | 10X Genomics, Inc. | Methods of decreasing background on a spatial array |
| US12405264B2 (en) | 2020-01-17 | 2025-09-02 | 10X Genomics, Inc. | Electrophoretic system and method for analyte capture |
| US20210230681A1 (en) | 2020-01-24 | 2021-07-29 | 10X Genomics, Inc. | Methods for spatial analysis using proximity ligation |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| US12281357B1 (en) | 2020-02-14 | 2025-04-22 | 10X Genomics, Inc. | In situ spatial barcoding |
| JP2023513606A (ja) | 2020-02-14 | 2023-03-31 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 核酸を評価するための方法および材料 |
| BR112022019541A2 (pt) | 2020-03-30 | 2022-11-16 | Illumina Inc | Métodos e composições para preparação de bibliotecas de ácido nucleico |
| KR20230035237A (ko) | 2020-05-12 | 2023-03-13 | 일루미나, 인코포레이티드 | 재조합 말단 데옥시뉴클레오티딜 트랜스퍼라제를 사용하여 변형된 염기를 갖는 핵산의 생성 |
| KR20230069047A (ko) * | 2020-09-14 | 2023-05-18 | 일루미나, 인코포레이티드 | 폴리뉴클레오티드를 증폭시키기 위한 조성물 및 방법 |
| EP4729631A2 (en) | 2020-12-21 | 2026-04-22 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| WO2022183121A1 (en) * | 2021-02-26 | 2022-09-01 | Avery Digital Data, Inc. | Semiconductor chip devices and methods for polynucleotide synthesis |
| US20240141420A1 (en) * | 2021-03-09 | 2024-05-02 | Todx Inc. | Parallel detection and quantification of nucleic acid based markers |
| EP4320271B1 (en) | 2021-05-06 | 2025-03-19 | 10X Genomics, Inc. | Methods for increasing resolution of spatial analysis |
| CN117813391A (zh) * | 2021-07-23 | 2024-04-02 | 因美纳有限公司 | 制备用于dna测序的基底表面的方法 |
| WO2023086880A1 (en) | 2021-11-10 | 2023-05-19 | 10X Genomics, Inc. | Methods, compositions, and kits for determining the location of an analyte in a biological sample |
| CN116179668A (zh) * | 2021-11-26 | 2023-05-30 | 复旦大学 | 靶向反应复合物及其在靶向多重检测中的用途 |
| CN114807196B (zh) * | 2022-03-30 | 2023-08-15 | 南京农业大学 | 一种追踪土传植物致病菌传播耐药基因的荧光标记方法 |
| WO2024102809A1 (en) | 2022-11-09 | 2024-05-16 | 10X Genomics, Inc. | Methods, compositions, and kits for determining the location of multiple analytes in a biological sample |
| US20240294982A1 (en) * | 2023-03-01 | 2024-09-05 | Personal Genomics Taiwan, Inc. | Method, kit and cartridge for detecting nucleic acid molecule |
| CN116297415B (zh) * | 2023-05-11 | 2023-08-18 | 细胞生态海河实验室 | 一种protac药物的筛选方法及载体 |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2044616A1 (en) | 1989-10-26 | 1991-04-27 | Roger Y. Tsien | Dna sequencing |
| US5223414A (en) | 1990-05-07 | 1993-06-29 | Sri International | Process for nucleic acid hybridization and amplification |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| WO1998030575A1 (en) | 1997-01-08 | 1998-07-16 | Proligo Llc | Bioconjugation of macromolecules |
| US6023540A (en) | 1997-03-14 | 2000-02-08 | Trustees Of Tufts College | Fiber optic sensor with encoded microspheres |
| US6327410B1 (en) | 1997-03-14 | 2001-12-04 | The Trustees Of Tufts College | Target analyte sensors utilizing Microspheres |
| US7427678B2 (en) | 1998-01-08 | 2008-09-23 | Sigma-Aldrich Co. | Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method |
| EP1923471B1 (en) | 1999-04-20 | 2012-12-19 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| US6355431B1 (en) | 1999-04-20 | 2002-03-12 | Illumina, Inc. | Detection of nucleic acid amplification reactions using bead arrays |
| US6274320B1 (en) | 1999-09-16 | 2001-08-14 | Curagen Corporation | Method of sequencing a nucleic acid |
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| US7001792B2 (en) | 2000-04-24 | 2006-02-21 | Eagle Research & Development, Llc | Ultra-fast nucleic acid sequencing device and a method for making and using the same |
| WO2002004680A2 (en) | 2000-07-07 | 2002-01-17 | Visigen Biotechnologies, Inc. | Real-time sequence determination |
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| EP2801624B1 (en) * | 2001-03-16 | 2019-03-06 | Singular Bio, Inc | Arrays and methods of use |
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| US8895249B2 (en) * | 2012-06-15 | 2014-11-25 | Illumina, Inc. | Kinetic exclusion amplification of nucleic acid libraries |
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| WO2014189768A1 (en) * | 2013-05-19 | 2014-11-27 | The Board Of Trustees Of The Leland | Devices and methods for display of encoded peptides, polypeptides, and proteins on dna |
| EP3234187B1 (en) * | 2014-12-15 | 2021-02-17 | Illumina, Inc. | Method for single molecular placement on a substrate |
-
2015
- 2015-12-14 EP EP15820734.0A patent/EP3234187B1/en active Active
- 2015-12-14 WO PCT/US2015/065526 patent/WO2016100196A1/en not_active Ceased
- 2015-12-14 CN CN202210176285.9A patent/CN114438172B/zh active Active
- 2015-12-14 EP EP21157018.9A patent/EP3882356A1/en active Pending
- 2015-12-14 ES ES15820734T patent/ES2870097T3/es active Active
- 2015-12-14 US US15/535,695 patent/US10350570B2/en active Active
- 2015-12-14 PT PT158207340T patent/PT3234187T/pt unknown
- 2015-12-14 DK DK15820734.0T patent/DK3234187T3/da active
- 2015-12-14 PL PL15820734T patent/PL3234187T3/pl unknown
- 2015-12-14 CN CN201580068109.1A patent/CN107223161B/zh active Active
-
2019
- 2019-06-06 US US16/433,346 patent/US10960377B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN107223161A (zh) | 2017-09-29 |
| EP3234187B1 (en) | 2021-02-17 |
| CN107223161B (zh) | 2022-03-22 |
| EP3234187A1 (en) | 2017-10-25 |
| WO2016100196A1 (en) | 2016-06-23 |
| US20190374923A1 (en) | 2019-12-12 |
| CN114438172B (zh) | 2025-02-21 |
| PL3234187T3 (pl) | 2021-10-25 |
| PT3234187T (pt) | 2021-05-26 |
| CN114438172A (zh) | 2022-05-06 |
| EP3882356A1 (en) | 2021-09-22 |
| US10960377B2 (en) | 2021-03-30 |
| US10350570B2 (en) | 2019-07-16 |
| US20180141020A1 (en) | 2018-05-24 |
| ES2870097T3 (es) | 2021-10-26 |
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